Iron Chelation in Patients with Myelodysplastic Syndromes and Myeloproliferative Neoplasms—Real-World Data from the German Noninterventional Study EXCALIBUR

Myelodysplastic syndromes and myeloproliferative neoplasms both represent hematologic diseases associated with bone marrow failure often resulting in anemia. For those patients, transfusion of red blood cell (RBC) units is essential but results in iron overload (IOL) that may affect various organ functions. Therefore, iron chelation therapy plays a major role in anemic patients, not only because it reduces IOL, but also because it may improve hematopoietic function by increasing hemoglobin or diminishing the requirement for RBC transfusions. To assess the utility, efficacy, and safety of the different iron chelation medications approved in Germany, as well as to examine the effect of chelation on hematopoietic insufficiency, a prospective, multicenter, noninterventional study named EXCALIBUR was designed. In total, 502 patients from 106 German hospitals and medical practices were enrolled. A large proportion of patients switched from a deferasirox dispersible tablet to a deferasirox-film-coated tablet, mainly because of more convenient application, which was reflected in the treatment satisfaction questionnaire for medication scores. Iron chelation was effective in lowering serum ferritin levels, with the observed adverse drug reactions being in line with the known safety profile. Hematologic response occurred in a few patients, comparable to other studies that examined hematologic improvement in patients with MDS

Выбор оптимального метода повышения нефтеотдачи на Новопортовском нефтегазоконденсатном месторождении (ЯНАО)

В работе проведен анализ современных методов увеличения нефтеотдачи. Выполнен анализ применяемых мероприятий, направленных на увеличения нефтеотдачи в рамках Новопортовского месторождения. Предложена технология увеличения нефтеотдачи, показана положительная эффективность применения технологии смешивающихся вытеснений.The analysis of modern methods of enhanced oil recovery is carried out. The analysis of the measures applied to increase oil recovery within the Novoportovskoye field has been carried out. The technology of enhanced oil recovery is proposed, the positive efficiency of the application of the technology of miscible displacement is shown

Development of a three-phase mathematical model of the catalytic cracking feedstock hydrotreating

Integration of mathematical models to the oil refining industry allows predicting the product composition and properties, as well as optimizing the process technological parameters without significant material and time costs. This paper describes an improved mathematical model of the vacuum distillate hydrotreating, taking into account presence of three phases in the system

Автоматизация построения геолого-технического наряда на строительство скважин

Tunnel junctions of Co(10 nm)/AlOx (nominally 2 nm)/Co(20 nm) have been prepared by molecular beam epitaxy applying a shadow mask technique in conjunction with an UV light-assisted oxidation process of the AlOx barrier. The quality of the AlOx barrier has been proven by x-ray photoelectron spectroscopy and temperature dependent tunneling magnetoresistance (TMR) measurements. Optimum-oxidized tunnel junctions show a TMR of 20% at 285 K and up to 36% at 100 K. At 285 K the TMR values as a function of oxidation time are not symmetric about the optimum time. For underoxidized junctions the TMR is reduced more strongly than for overoxidized junctions. The temperature dependence of the junction s resistance is a clear and reliable indicator whether pinholes (or imperfections)contribute to the conduction across the barrier

Разработка технологии изготовления детали «Втулка подшипника»

Цели и задачи исследования: создание эффективного маршрута технологического процесса изготовления детали "Втулка подшипника". В работе изложено обоснование выполнение ВКР, выполнен анализ чертежа детали и её технологичности, определен тип производства, описан принцип выбора заготовки в соответствие с её материалом и серийностью производства, выполнен чертёж заготовки, разработан маршрут обработки детали с представлением операционных эскизов и описанием переходов по каждой операции, рассчитаны припуски на обработку и технологические размеры, выполнен размерный анализ техпроцесса с уточнением технологических размеров, рассчитаны режимы резания и требуемая мощность оборудования для каждой операции, назначена модель станка, рассчитано время выполнения каждой операции.The paper presents the rationale for the implementation of Diploma Thesis, the analysis of the drawing of the part and its technology, the type of production, the principle of selection of procurement in accordance with its material and serial production, carried out a drawing of the initial workpiece, the route processing of detail with operational sketches and descriptions of transitions for each operation, calculated allowances for processing and technological dimensions, is made dimensional analysis of the process with the specification of the technological dimensions, the cutting modes for each technological transition and the required power of the equipment for each operation are calculated, the machine model is assigned, and the execution time for each operation is calculated

Device Performance of Emerging Photovoltaic Materials (Version 3)

Following the 2nd release of the “Emerging PV reports,” the best achievements in the performance of emerging photovoltaic devices in diverse emerging photovoltaic research subjects are summarized, as reported in peer-reviewed articles in academic journals since August 2021. Updated graphs, tables, and analyses are provided with several performance parameters, e.g., power conversion efficiency, open-circuit voltage, short-circuit current density, fill factor, light utilization efficiency, and stability test energy yield. These parameters are presented as a function of the photovoltaic bandgap energy and the average visible transmittance for each technology and application, and are put into perspective using, e.g., the detailed balance efficiency limit. The 3rd installment of the “Emerging PV reports” extends the scope toward triple junction solar cells

Device Performance of Emerging Photovoltaic Materials (Version 3)

Following the 2nd release of the “Emerging PV reports,” the best achievements in the performance of emerging photovoltaic devices in diverse emerging photovoltaic research subjects are summarized, as reported in peer-reviewed articles in academic journals since August 2021. Updated graphs, tables, and analyses are provided with several performance parameters, e.g., power conversion efficiency, open-circuit voltage, short-circuit current density, fill factor, light utilization efficiency, and stability test energy yield. These parameters are presented as a function of the photovoltaic bandgap energy and the average visible transmittance for each technology and application, and are put into perspective using, e.g., the detailed balance efficiency limit. The 3rd installment of the “Emerging PV reports” extends the scope toward triple junction solar cells

Device Performance of Emerging Photovoltaic Materials (Version 2)

Following the 1st release of the “Emerging photovoltaic (PV) reports”, the best achievements in the performance of emerging photovoltaic devices in diverse emerging photovoltaic research subjects are summarized, as reported in peer-reviewed articles in academic journals since August 2020. Updated graphs, tables, and analyses are provided with several performance parameters, e.g., power conversion efficiency, open-circuit voltage, short-circuit current density, fill factor, light utilization efficiency, and stability test energy yield. These parameters are presented as a function of the photovoltaic bandgap energy and the average visible transmittance for each technology and application and are put into perspective using, e.g., the detailed balance efficiency limit. The 2nd instalment of the “Emerging PV reports” extends the scope toward tandem solar cells and presents the current state-of-the-art in tandem solar cell performance for various material combinations.</p

Device Performance of Emerging Photovoltaic Materials (Version 1)

Emerging photovoltaics (PVs) focus on a variety of applications complementing large scale electricity generation. Organic, dye‐sensitized, and some perovskite solar cells are considered in building integration, greenhouses, wearable, and indoor applications, thereby motivating research on flexible, transparent, semitransparent, and multi‐junction PVs. Nevertheless, it can be very time consuming to find or develop an up‐to‐date overview of the state‐of‐the‐art performance for these systems and applications. Two important resources for recording research cells efficiencies are the National Renewable Energy Laboratory chart and the efficiency tables compiled biannually by Martin Green and colleagues. Both publications provide an effective coverage over the established technologies, bridging research and industry. An alternative approach is proposed here summarizing the best reports in the diverse research subjects for emerging PVs. Best performance parameters are provided as a function of the photovoltaic bandgap energy for each technology and application, and are put into perspective using, e.g., the Shockley–Queisser limit. In all cases, the reported data correspond to published and/or properly described certified results, with enough details provided for prospective data reproduction. Additionally, the stability test energy yield is included as an analysis parameter among state‐of‐the‐art emerging PVs