Biomolecular imaging and electronic damage using X-ray free-electron lasers

Proposals to determine biomolecular structures from diffraction experiments using femtosecond X-ray free-electron laser (XFEL) pulses involve a conflict between the incident brightness required to achieve diffraction-limited atomic resolution and the electronic and structural damage induced by the illumination. Here we show that previous estimates of the conditions under which biomolecular structures may be obtained in this manner are unduly restrictive, because they are based on a coherent diffraction model that is not appropriate to the proposed interaction conditions. A more detailed imaging model derived from optical coherence theory and quantum electrodynamics is shown to be far more tolerant of electronic damage. The nuclear density is employed as the principal descriptor of molecular structure. The foundations of the approach may also be used to characterize electrodynamical processes by performing scattering experiments on complex molecules of known structure.Comment: 16 pages, 2 figure

An Observational Limit on the Dwarf Galaxy Population of the Local Group

We present the results of an all-sky, deep optical survey for faint Local Group dwarf galaxies. Candidate objects were selected from the second Palomar survey (POSS-II) and ESO/SRC survey plates and follow-up observations performed to determine whether they were indeed overlooked members of the Local Group. Only two galaxies (Antlia and Cetus) were discovered this way out of 206 candidates. Based on internal and external comparisons, we estimate that our visual survey is more than 77% complete for objects larger than one arc minute in size and with a surface brightness greater than an extremely faint limit over the 72% of the sky not obstructed by the Milky Way. Our limit of sensitivity cannot be calculated exactly, but is certainly fainter than 25 magnitudes per square arc second in R, probably 25.5 and possibly approaching 26. We conclude that there are at most one or two Local Group dwarf galaxies fitting our observational criteria still undiscovered in the clear part of the sky, and a roughly a dozen hidden behind the Milky Way. Our work places the "missing satellite problem" on a firm quantitative observational basis. We present detailed data on all our candidates, including surface brightness measurements.Comment: 58 pages in AJ manuscript format; some figures at slightly reduced quality; accepted by the Astronomical Journa

Superradiant light scattering and grating formation in cold atomic vapours

A semi-classical theory of coherent light scattering from an elongated sample of cold atoms exposed to an off-resonant laser beam is presented. The model, which is a direct extension of that of the collective atomic recoil laser (CARL), describes the emission of two superradiant pulses along the sample's major axis simultaneous with the formation of a bidimensional atomic grating inside the sample. It provides a simple physical picture of the recent observation of collective light scattering from a Bose-Einstein condensate [S. Inouye et al., Science N.285, p. 571 (1999)]. In addition, the model provides an analytical description of the temporal evolution of the scattered light intensity which shows good quantitative agreement with the experimental results of Inouye et al.Comment: submitted to Optics Communications, LaTex version, 2 postscript figure

Novelty Induces Behavioural And Glucocorticoid Responses In A Songbird Artificially Selected For Divergent Personalities

Stress physiology is thought to contribute to individual differences in behaviour. In part this reflects the fact that canonical personality measures consist of responses to challenges, including novel objects and environments. Exposure to novelty is typically assumed to induce a moderate increase in glucocorticoids (CORT), although this has rarely been tested. We tested this assumption using great tits, Parus major, selected for divergent personalities (bold-fast and shy-slow explorers), predicting that the shy birds would exhibit higher CORT following exposure to a novel object. We also scored behavioural responses to the novel object, predicting that bold birds would more frequently approach the novel object and exhibit more abnormal repetitive behaviours. We found that the presence of a novel object did induce a moderate CORT response, but selection lines did not differ in the magnitude of this response. Furthermore, although both selection lines showed a robust CORT elevation to a subsequent restraint stressor, the CORT response was stronger in bold birds and this effect was specific to novel object exposure. Shy birds showed a strong positive phenotypic correlation between CORT concentrations following the novel object exposure and the subsequent restraint stress. Behaviourally, the selection lines differed in their response during novel object exposure: as predicted, bold birds more frequently approached the novel object and shy birds more strongly decreased overall locomotion during the novel object trial, but birds from both selection lines showed significant and similar frequencies of abnormal repetitive behaviours during novel object exposure. Our findings support the hypothesis that personality emerges as a result of correlated selection on behaviour and underlying endocrine mechanisms and suggest that the relationship between endocrine stress physiology and personality is context dependent

Fish schooling as a basis for vertical axis wind turbine farm design

Most wind farms consist of horizontal axis wind turbines (HAWTs) due to the high power coefficient (mechanical power output divided by the power of the free-stream air through the turbine cross-sectional area) of an isolated turbine. However when in close proximity to neighbouring turbines, HAWTs suffer from a reduced power coefficient. In contrast, previous research on vertical axis wind turbines (VAWTs) suggests that closely-spaced VAWTs may experience only small decreases (or even increases) in an individual turbine's power coefficient when placed in close proximity to neighbours, thus yielding much higher power outputs for a given area of land. A potential flow model of inter-VAWT interactions is developed to investigate the effect of changes in VAWT spatial arrangement on the array performance coefficient, which compares the expected average power coefficient of turbines in an array to a spatially-isolated turbine. A geometric arrangement based on the configuration of shed vortices in the wake of schooling fish is shown to significantly increase the array performance coefficient based upon an array of 16x16 wind turbines. Results suggest increases in power output of over one order of magnitude for a given area of land as compared to HAWTs.Comment: Submitted for publication in BioInspiration and Biomimetics. Note: The technology described in this paper is protected under both US and international pending patents filed by the California Institute of Technolog

The limits of the rotating wave approximation in the electromagnetic field propagation in a cavity

We consider three two-level atoms inside a one-dimensional cavity, interacting with the electromagnetic field in the rotating wave approximation (RWA), commonly used in the atom-radiation interaction. One of the three atoms is initially excited, and the other two are in their ground state. We numerically calculate the propagation of the field spontaneously emitted by the excited atom and scattered by the second atom, as well as the excitation probability of the second and third atom. The results obtained are analyzed from the point of view of relativistic causality in the atom-field interaction. We show that, when the RWA is used, relativistic causality is obtained only if the integrations over the field frequencies are extended to $-\infty$; on the contrary, noncausal tails remain even if the number of field modes is increased. This clearly shows the limit of the RWA in dealing with subtle problems such as relativistic causality in the atom-field interaction.Comment: 13 pages, 6 figure

The perceived quality and impact of the Tulsa model evaluation: a survey of teachers and principals in Oklahoma public schools

Oklahoma began implementing its Teacher Leader Effectiveness Law in 2011, the state’s response to competing for federal Race to the Top grant money and the nation-wide cry from education reformers for tougher teacher evaluation mandates in public schools. This quantitative analysis of variance study explores the effectiveness of the law’s implementation in Oklahoma school districts using the Tulsa Model Evaluation process in the fall of 2019. A guiding theoretical framework for this study is based in the research of Stiggins and Nickel (1989) and Stiggins and Duke (1988) and their findings of the usefulness of the Teacher Evaluation Profile to measure conditions for teacher growth using standards-based evaluation instruments. A cross-sectional survey distributed to principals and teachers gathered perceptions of the quality and impact of the Tulsa Model Evaluation process based on six key areas: knowledge and understanding of the evaluation system; perceptions regarding usefulness; qualifications and evaluator leadership; quality of data and feedback from principals; impact on professional practices; and personal impressions of the evaluation system on professional conversations. The study uses a Welch alternative ANOVA to determine the differences in perceived quality and impact of the Tulsa Model evaluation instrument between principals and teachers in 54 Oklahoma schools. The following research questions were addressed: 1. Do principals and teachers differ in their perceptions of knowledge and understanding of the Tulsa Model Evaluation process and if so, to what degree? 2. Do principals and teachers differ in their perceptions of the usefulness of the Tulsa Model Evaluation process and if so, to what degree? 3. Do principals and teachers differ in their perceptions of the qualification of the evaluator and if so, to what degree? 4. Do principals and teachers differ in their perceptions of the quality of data and feedback in the Tulsa Model Evaluation process and if so, to what degree? 5. Do principals and teachers differ in their perceptions of the impact on professional practices for the Tulsa Model Evaluation process and if so, to what degree? 6. Do principals and teachers differ in their perceptions of the context of professional conversations during the Tulsa Model Evaluation process and if so, to what degree? Results determined there are significant differences between principal and teacher responses to survey questions with the greatest degree of difference in three key areas: 1. knowledge and understanding of the evaluation; 2. usefulness of the process; and 3. quality of data and feedback