56 research outputs found

    \u3cem\u3eThe Middleton Place Privy House: An Archeological View of Nineteenth Centry Plantation Life\u3c/em\u3e

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    This publication, published by the University of South Carolina\u27s South Carolina Institute of Archaeology and Anthropology, is the first issue of the Institute\u27s Popular Series. Contents: Table of Contents.....p. iii List of Figures.....p. iv Acknowledgements.....p. vi A Brief History of Middleton Place.....p. 1 Archeology at Middleton Place.....p. 8 Pottery and Porcelain.....p. 12 Glass Tableware.....p. 24 Glass Manufacture in the United States.....p. 29 Medicine Bottles.....p. 34 Wine and Spirits Bottles.....p. 39 Beer Bottles.....p. 40 Carolina Dispensary Bottles.....p. 43 Food Containers.....p. 45 Bottles Made After 1900.....p. 47 Lamp Glass.....p. 49 Laboratory Glass.....p. 52 Conclusions.....p. 54 Appendix I - Ceramic Manufacturer\u27s Marks.....p. 56 Appendix II - Significant Dates in the American Glass Industry.....p. 58 Appendix III - Marks Left by Different Techniques of Bottle Manufacture.....p. 62 Appendix IV - Artifact Catalogue from the Middleton Place Privy Excavation.....p. 64 Bibliography.....p. 7

    Hampton II: Further Archeological Investigations at a Santee River Rice Plantation

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    https://scholarcommons.sc.edu/archanth_books/1153/thumbnail.jp

    The Middleton Place Privy: A Study of Discard Behavior and the Archeological Record

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    https://scholarcommons.sc.edu/archanth_books/1165/thumbnail.jp

    Modeling Subsistence Change in the Late Prehistoric Period in the Interior Lower Coastal Plain of South Carolina

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    Recent research on Middle-Late Woodland and Mississippian subsistence-settlement change has modified substantially the traditional models of late fall, coastal to interior transhumance patterns along the southeastern Atlantic Coast. The archeological, ethnohistorical, and environmental data suggest that the interior Lower Coastal Plain of South Carolina was exploited on a year-round basis during the late prehistoric period. These data and those recovered from two archeological sites, which were investigated by the Institute of Archeology and Anthropology for the U. S. Army Corps of Engineers\u27 Cooper River Rediversion Project, indicate differences in the subsistence strategies between the Middle-Late Woodland and Mississippian populations, however. The Middle-Late Woodland settlement pattern appears to reflect generalized exploitation of riverine and interriverine resources, whereas the Mississippian exploitation strategy apparently focuses on the intensive exploitation of a relatively narrow range of specific, high density, riverine resources. A series of interrelated hypotheses, deduced from economic ecological theory, characterizes the expected nature of these differences. The hypotheses are tested using paleoecological data and deriving archeological measures of functional variability for the artifact assemblages recovered from sites 38BK235 and 3BBK236 located in the riverine zone. The results support intensive exploitation of the interior riverine zone in the summer and early fall by both Middle-Late Woodland and Mississippian groups, with the Mississippian occupation having more and better defined activity areas and showing a greater range of diversity and functional specificity in the artifact assemblage.https://scholarcommons.sc.edu/archanth_anthro_studies/1006/thumbnail.jp

    Agouti signalling protein is an inverse agonist to the wildtype and agonist to the melanic variant of the melanocortin-1 receptor in the grey squirrel (Sciurus carolinensis)

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    The melanocortin-1 receptor (MC1R) is a key regulator of mammalian pigmentation. Melanism in the grey squirrel is associated with an eight amino acid deletion in the mutant melanocortin-1 receptor with 24 base pair deletion (MC1RΔ24) variant. We demonstrate that the MC1RΔ24 exhibits a higher basal activity than the wildtype MC1R (MC1R-wt). We demonstrate that agouti signalling protein (ASIP) is an inverse agonist to the MC1R-wt but is an agonist to the MC1RΔ24. We conclude that the deletion in the MC1RΔ24 leads to a receptor with a high basal activity which is further activated by ASIP. This is the first report of ASIP acting as an agonist to MC1R

    Quality metrics for the evaluation of Rapid Response Systems: Proceedings from the third international consensus conference on Rapid Response Systems.

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    BACKGROUND: Clinically significant deterioration of patients admitted to general wards is a recognized complication of hospital care. Rapid Response Systems (RRS) aim to reduce the number of avoidable adverse events. The authors aimed to develop a core quality metric for the evaluation of RRS. METHODS: We conducted an international consensus process. Participants included patients, carers, clinicians, research scientists, and members of the International Society for Rapid Response Systems with representatives from Europe, Australia, Africa, Asia and the US. Scoping reviews of the literature identified potential metrics. We used a modified Delphi methodology to arrive at a list of candidate indicators that were reviewed for feasibility and applicability across a broad range of healthcare systems including low and middle-income countries. The writing group refined recommendations and further characterized measurement tools. RESULTS: Consensus emerged that core outcomes for reporting for quality improvement should include ten metrics related to structure, process and outcome for RRS with outcomes following the domains of the quadruple aim. The conference recommended that hospitals should collect data on cardiac arrests and their potential predictability, timeliness of escalation, critical care interventions and presence of written treatment goals for patients remaining on general wards. Unit level reporting should include the presence of patient activated rapid response and metrics of organizational culture. We suggest two exploratory cost metrics to underpin urgently needed research in this area. CONCLUSION: A consensus process was used to develop ten metrics for better understanding the course and care of deteriorating ward patients. Others are proposed for further development

    Safety, immunogenicity, and reactogenicity of BNT162b2 and mRNA-1273 COVID-19 vaccines given as fourth-dose boosters following two doses of ChAdOx1 nCoV-19 or BNT162b2 and a third dose of BNT162b2 (COV-BOOST): a multicentre, blinded, phase 2, randomised trial

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