Gender-role development in toddlers: The association between parental gender-role orientation and toddler\u27s gender-typed behavior

Associations between the gender-role orientation of parents and the toy-play behavior of first-born infants were investigated. Fifteen fathers ( M age = 31.13, SD = 4.26) and 46 mothers ( M age = 28.13, SD = 4.97) completed self-administered questionnaires which included questions on feedback to play with gender-typed toys. ANOVA results indicated that mothers provided more masculine-typed toys for their sons than their daughters, and more feminine-typed toys for their daughters than their sons; fathers provided more feminine-typed toys for their daughters than their sons. In addition, mothers provided more encouragement to same-gender-typed play than cross-gender-typed play for both masculine- and feminine-typed toys, while fathers provided more encouragement to their daughters playing with feminine-typed toys than their sons. Results are discussed in terms of the gender-role socialization processes in which parents of young children engage, and the possibility of bidirectional socialization processes

Green and black tea for the primary prevention of cardiovascular disease

Background: There is increasing evidence that both green and black tea are beneficial for cardiovascular disease (CVD) prevention. Objectives: To determine the effects of green and black tea on the primary prevention of CVD. Search methods: We searched the following databases on 12 October 2012 without language restrictions: CENTRAL in The Cochrane Library, MEDLINE (OVID), EMBASE (OVID) and Web of Science (Thomson Reuters). We also searched trial registers, screened reference lists and contacted authors for additional information where necessary. Selection criteria: Randomised controlled trials (RCTs) lasting at least three months involving healthy adults or those at high risk of CVD. Trials investigated the intake of green tea, black tea or tea extracts. The comparison group was no intervention, placebo or minimal intervention. The outcomes of interest were CVD clinical events and major CVD risk factors. Any trials involving multifactorial lifestyle interventions or focusing on weight loss were excluded to avoid confounding. Data collection and analysis: Two review authors independently selected trials for inclusion, abstracted data and assessed the risk of bias. Trials of green tea were analysed separately from trials of black tea. Main results: We identified 11 RCTs with a total of 821 participants, two trials awaiting classification and one ongoing trial. Seven trials examined a green tea intervention and four examined a black tea intervention. Dosage and form of both green and black tea differed between trials. The ongoing trial is examining the effects of green tea powder capsules. No studies reported cardiovascular events. Black tea was found to produce statistically significant reductions in low-density lipoprotein (LDL) cholesterol (mean difference (MD) -0.43 mmol/L, 95% confidence interval (CI) -0.56 to -0.31) and blood pressure (systolic blood pressure (SBP): MD -1.85 mmHg, 95% CI -3.21 to -0.48. Diastolic blood pressure (DBP): MD -1.27 mmHg, 95% CI -3.06 to 0.53) over six months, stable to sensitivity analysis, but only a small number of trials contributed to each analysis and studies were at risk of bias. Green tea was also found to produce statistically significant reductions in total cholesterol (MD -0.62 mmol/L, 95% CI -0.77 to - 0.46), LDL cholesterol (MD -0.64 mmol/L, 95% CI -0.77 to -0.52) and blood pressure (SBP: MD -3.18 mmHg, 95% CI -5.25 to - 1.11; DBP: MD -3.42, 95% CI -4.54 to -2.30), but only a small number of studies contributed to each analysis, and results were not stable to sensitivity analysis. When both tea types were analysed together they showed favourable effects on LDL cholesterol (MD - 0.48 mmol/L, 95% CI -0.61 to -0.35) and blood pressure (SBP: MD -2.25 mmHg, 95% CI -3.39 to -1.11; DBP: MD -2.81 mmHg, 95% CI -3.77 to -1.86). Adverse events were measured in five trials and included a diagnosis of prostate cancer, hospitalisation for influenza, appendicitis and retinal detachment but these are unlikely to be directly attributable to the intervention. Authors' conclusions: There are very few long-term studies to date examining green or black tea for the primary prevention of CVD. The limited evidence suggests that tea has favourable effects on CVD risk factors, but due to the small number of trials contributing to each analysis the results should be treated with some caution and further high quality trials with longer-term follow-up are needed to confirm this

Maine\u27s Rural Health Challenges

This brief describes the issues affecting access to health care in rural Maine. These issues include Maine’s use of enhanced Medicare and Medicaid payments to support the rural health infrastructure, the adequacy of the provider workforce and the presence of training programs, the contribution of health care to the rural economy, and the high prevalence and unmet need for care for persons with substance use and mental health issues

Short-Term Therapy with Peroxisome Proliferation-Activator Receptor-Agonist Wy-14,643 Protects Murine Fatty Liver Against Ischemia-Reperfusion Injury

Steatosis increases operative morbidity/mortality from ischemia-reperfusion injury (IRI); few pharmacological approaches have been protective. Using novel genetic/dietary models of nonalcoholic steatohepatitis (NASH) and simple steatosis (SS) in Alms1 mutant (foz/foz) mice, we characterized severity of IRI in NASH versus SS and lean liver and tested our hypothesis that the lipid-lowering effects of the peroxisome proliferation-activator receptor (PPAR)-agonist Wy-14,643 would be hepatoprotective. Mice were subjected to 60-minute partial hepatic IRI. Microvascular changes were assessed at 15-minute reperfusion by in vivo microscopy, injury at 24 hours by serum alanine aminotransferase (ALT), and hepatic necrosis area. Injury and inflammation mediators were determined by way of immunoblotting for intercellular cellular adhesion molecule, vascular cellular adhesion molecule, p38, c-jun N-terminal kinase, IB-, interleukin (IL)-1a, IL-12, tumor necrosis factor-(TNF-) and IL-6, cell cycle by cyclin D1 and proliferating cell nuclear antigen immunohistochemistry. In foz/foz mice fed a high-fat diet (HFD) to cause NASH or chow (SS), IRI was exacerbated compared with HFD-fed or chow-fed wild-type littermates by ALT release; corresponding necrotic areas were 60 22%NASH, 29 9%SS versus 7 1%lean. Microvasculature of NASH or SS livers was narrowed by enormous lipid-filled hepatocytes, significantly reducing numbers of perfused sinusoids, all exacerbated by IRI. Wy-14,643 reduced steatosis in NASH and SS livers, whereas PPAR-stimulation conferred substantial hepatoprotection against IRI by ALT release, with reductions in vascular cellular adhesion molecule-1, IL-1a, TNF-, IL-12, activated nuclear factor-B (NF-B), p38, IL-6 production and cell cycle entry. Conclusion: NASH and SS livers are both more susceptible to IRI. Mechanisms include possible distortion of the microvasculature by swollen fat-laden hepatocytes, and enhanced production of several cytokines. The beneficial effects of Wy-14,643 may be exerted by dampening adhesion molecule and cytokine responses, and activating NF-B, IL-6 production, and p38 kinase to effect cell cycle entry

Association of cognition with functional trajectories in patients admitted to geriatric wards: A retrospective observational study.

AIM: Impaired cognition is common among older patients admitted to acute hospitals, but its association with functional trajectories has not been well studied. METHODS: A retrospective observational study was carried out in an English tertiary university hospital. We analyzed all first episodes of county residents aged ≥75 years admitted to the Department of Medicine for the Elderly wards between December 2014 and May 2015. A history of dementia or a cognitive concern in the absence of a known diagnosis of dementia were recorded on admission. A cognitive concern included possible undiagnosed dementia or delirium. Function was retrospectively measured with the modified Rankin Scale at preadmission baseline, admission and discharge. RESULTS: There were 663 first hospital episodes over the period, of which 590 patients survived. Among the latter, 244 had no cognitive impairment, 134 a diagnosis of dementia, 66 a cognitive concern in the absence of a known dementia and 146 had missing cognitive data. When frailty, acuity, age and comorbidity were controlled for, people with known dementia had a similar functional recovery compared with those with no cognitive impairment. People with a cognitive concern, but no known dementia, had lesser functional recovery and greater disability at discharge than those with no cognitive impairment (mean discharge modified Rankin Scale 3.4 compared with 3.1, P = 0.011). CONCLUSIONS: Dementia per se might not be a marker of poor rehabilitation potential. Older people with acute cognitive concerns might be more vulnerable to poor functional recovery. Our cognitive variables are not gold standard, and further research is required to clarify this relationship. Geriatr Gerontol Int 2017; 17: 1438-1443.This is the author accepted manuscript. The final version is available from Wiley via https://doi.org/10.1111/ggi.1288

Implications of rurality and psychiatric status for diabetic care use among adults with diabetes

This research examined patterns of diabetic preventive care use among adults with diabetes, to determine whether these patterns varied according to respondents’ rural/urban residence or psychiatric status (i.e., the presence/absence of a mental health diagnosis). Specifically, we considered whether rural people with diabetes are less likely than urban peers to use diabetic preventive services; whether having a mental health diagnosis affects preventive service use among diabetics; and, whether rural/ urban differences in service use vary depending on the presence or absence of a mental health diagnosis

Adolescent Alcohol Use: Do Risk and Protective Factors Explain Rural-Urban Differences? [Working Paper]

Using data from the 2008-2009 National Survey of Drug Use and Health, this study examines alcohol use among rural and urban adolescents between the ages of 12 and 17. We conduct bivariate and multivariate analyses of the prevalence of alcohol use across rural and urban areas and the relationships between alcohol use and potential protective or risk factors including parent relations, peer relations, school relations, and religious involvement

Adolescent Alcohol Use: Do risk and protective factors explain rural-urban differences? [Policy Brief]

Adolescent alcohol use is a significant public health problem among U.S. adolescents. Past studies, including our own work, have found that rural adolescents were more likely to use alcohol than urban adolescents. Research suggests that protective factors, such as peer and parental disapproval, may be weaker among youth living in rural areas. This study examines the factors associated with adolescent alcohol use, whether they differ between rural and urban populations, and the extent to which these differences account for rural-urban variations in adolescent alcohol use. This knowledge is crucial to the development of rural-specific prevention strategies, targeted research on rural adolescent alcohol use, and long-term policy interventions. Our findings confirm higher rates of binge drinking and driving under the influence among rural youth than among urban youth. Rural residence is associated with increased odds of binge drinking (OR 1.16, p\u3c .05) and driving under the influence (OR 1.42, p\u3c .001) even when income and protective factors are taken into account. Our findings suggest that adolescents who start drinking at an earlier age are more likely to engage in problem drinking behavior as they get older, leading to a need for interventions that target pre-teens and younger adolescents. Moreover, since we found urban-rural differences in specific protective factors, these may be the most promising for evidence-based, rural-specific prevention strategies targeting parents, schools, and churches. These are the factors that convey and reinforce consistent messages discouraging adolescent alcohol use from an early age

Reliability of a feedback-controlled treadmill algorithm dependent on the user\u27s behavior

he reliability of the treadmill belt speed using a feedback-controlled treadmill algorithm was analyzed in this study. Using biomechanical factors of the participant\u27s walking behavior, an estimated walking speed was calculated and used to adjust the speed of the treadmill. Our proposed algorithm expands on the current hypotheses of feedback-controlled treadmill algorithms and is presented below. Nine healthy, young adults walked on a treadmill controlled by the algorithm for three trials over two days. Each participant walked on the feedback-controlled treadmill for one 16-minute and one five-minute trial during day one and one 16-minute trial during day two. Mean, standard deviation, interclass correlation coefficient (ICC), and standard error of measurement (SEM) were analyzed on the treadmill belt speed mean, standard deviation, and coefficient of variation. There were significantly high ICC for mean treadmill speed within- and between-days. Treadmill speed standard deviation and coefficient of variation were significantly reliable within-day. These results suggest the algorithm will reliably produce the same treadmill belt speed mean, but may only produce a similar treadmill belt speed standard deviation and coefficient of variation if the trials are performed in the same day. A feedback-controlled treadmill algorithm that accounts for the user\u27s behavior provides a greater level of control and minimizes any possible constraints of walking on a conventional treadmill

Separation of nickel from cobalt and manganese in lithium ion batteries using deep eutectic solvents

The authors would like to thank the Faraday Institution (grant codes FIRG005 and FIRG006) for funding (Project website https://relib.org.uk). This research also received funding from the European Commission's H2020 – Marie Sklodowska Curie Actions (MSCA) − Innovative Training Networks within the SOCRATES project under the grant agreement no. 721385 (Project website: https://etn-socrates.eu).A cornerstone of the decarbonisation agenda is the use of lithium ion batteries, particularly for electric vehicles. It is essential that effective recycling protocols are developed and this includes the ability to selectively digest and recover components of the cathode materials, most commonly including manganese, cobalt and nickel. This study shows a method by which nickel oxide can be efficiently separated from cobalt and manganese oxides using an oxalic acid-based deep eutectic solvent. The subsequent addition of water to the pregnant solution enables the co-precipitation of cobalt and manganese oxalates. This permits a route to the reformulation of the active materials from high cobalt and manganese content to high nickel content.Publisher PDFPeer reviewe