1,005 research outputs found
Flow past superhydrophobic surfaces with cosine variation in local slip length
Anisotropic super-hydrophobic surfaces have the potential to greatly reduce
drag and enhance mixing phenomena in microfluidic devices. Recent work has
focused mostly on cases of super-hydrophobic stripes. Here, we analyze a
relevant situation of cosine variation of the local slip length. We derive
approximate formulae for maximal (longitudinal) and minimal (transverse)
directional effective slip lengths that are in good agreement with the exact
numerical solution and lattice-Bolzmann simulations for any surface slip
fraction. The cosine texture can provide a very large effective (forward) slip,
but it was found to be less efficient in generating a transverse flow as
compared to super-hydrophobic stripes.Comment: 8 pages, 6 figure
Random-roughness hydrodynamic boundary conditions
We report results of lattice Boltzmann simulations of a high-speed drainage
of liquid films squeezed between a smooth sphere and a randomly rough plane. A
significant decrease in the hydrodynamic resistance force as compared with that
predicted for two smooth surfaces is observed. However, this force reduction
does not represent slippage. The computed force is exactly the same as that
between equivalent smooth surfaces obeying no-slip boundary conditions, but
located at an intermediate position between peaks and valleys of asperities.
The shift in hydrodynamic thickness is shown to depend on the height and
density of roughness elements. Our results do not support some previous
experimental conclusions on very large and shear-dependent boundary slip for
similar systems.Comment: 4 pages, 4 figure
Recent Advances in the Treatment of Complex Congenital Diaphragmatic Hernia-A Narrative Review
BACKGROUND AND OBJECTIVE: Congenital diaphragmatic hernia (CDH) is an anomaly of the cardiopulmonary system maturation process that results from both a global embryopathy and concomitant mechanical compression of the cardiopulmonary system from the abdominal contents during fetal maturation. This results in pulmonary hypertension, pulmonary hypoplasia, and cardiac dysfunction, requiring intense critical care management. The patients with highest risk CDH are the most challenging, resource-intensive, and bear most of the mortality. Advances at the basic, translational, and clinical research levels are leading to novel therapies and management strategies for complex, high-risk CDH. Our objective is to review novel approaches in thinking and management for the most complex and high-risk CDH patients. These include patients with prenatal and postnatal indicators of high-risk defects, those receiving extracorporeal life support (ECLS), and those with concomitant anomalies such as complex cardiac and/or chromosomal abnormalities.
METHODS: PubMed was searched in late 2022 and early 2023 to identify relevant evidence. Search terms included congenital diaphragmatic hernia (CDH) , extracorporeal life support (ECLS) , pulmonary hypertension , dual-hit hypothesis , risk reduction , cardiac/chromosomal anomalies , and novel therapies . We included trials, multicenter studies (prospective and retrospective), single-center reports, and review articles/expert opinion.
KEY CONTENT AND FINDINGS: CDH is a congenital anomaly of the cardiopulmonary and diaphragmatic systems that represents a spectrum of disease. High-risk or complex patients are defined by prenatal/postnatal risk stratification, receipt of ECLS, and/or having concomitant anomalies, representing the severe end of that spectrum. Overall survival of high-risk CDH is about 50% and comprises the vast majority of mortality, mandating special emphasis. The development of risk-stratification processes, best practices or guidelines of management, and novel therapies is critical to optimize the care of these infants.
CONCLUSIONS: CDH patients with high-risk disease remain a challenging subset of CDH patients. Increasing opportunities for survival are being realized with novel, investigational approaches
Electroneutrality breakdown for electrolytes embedded in varying-section nanopores
We determine the local charge dynamics of a electrolyte embedded in a
varying-section channel. By means of an expansion based on the length scale
separation between the axial and transverse direction of the channel, we derive
closed formulas for the local excess charge for both, dielectric and conducting
walls, in (planar geometry) as well as in (cylindrical geometry). Our
results show that, even at equilibrium, the local charge electroneutrality is
broken whenever the section of the channel is not homogeneous for both
dielectric and conducting walls as well as for and channels.
Interestingly, even within our expansion, the local excess charge in the fluid
can be comparable to the net charge on the walls. We critically discuss the
onset of such local electroneutrality breakdown in particular with respect to
the correction that it induces on the effective free energy profile experienced
by tracer ions
Lattice-Boltzmann simulations of the drag force on a sphere approaching a superhydrophobic striped plane
By means of lattice-Boltzmann simulations the drag force on a sphere of
radius R approaching a superhydrophobic striped wall has been investigated as a
function of arbitrary separation h. Superhydrophobic (perfect-slip vs. no-slip)
stripes are characterized by a texture period L and a fraction of the gas area
. For very large values of h/R we recover the macroscopic formulae for a
sphere moving towards a hydrophilic no-slip plane. For h/R=O(1) and smaller the
drag force is smaller than predicted by classical theories for hydrophilic
no-slip surfaces, but larger than expected for a sphere interacting with a
uniform perfectly slipping wall. At a thinner gap, the force reduction
compared to a classical result becomes more pronounced, and is maximized by
increasing . In the limit of very small separations our simulation data
are in quantitative agreement with an asymptotic equation, which relates a
correction to a force for superhydrophobic slip to texture parameters. In
addition, we examine the flow and pressure field and observe their oscillatory
character in the transverse direction in the vicinity of the wall, which
reflects the influence of the heterogeneity and anisotropy of the striped
texture. Finally, we investigate the lateral force on the sphere, which is
detectable in case of very small separations and is maximized by stripes with
.Comment: 9 pages, 7 figure
Implementation of on-site velocity boundary conditions for D3Q19 lattice Boltzmann
On-site boundary conditions are often desired for lattice Boltzmann
simulations of fluid flow in complex geometries such as porous media or
microfluidic devices. The possibility to specify the exact position of the
boundary, independent of other simulation parameters, simplifies the analysis
of the system. For practical applications it should allow to freely specify the
direction of the flux, and it should be straight forward to implement in three
dimensions. Furthermore, especially for parallelized solvers it is of great
advantage if the boundary condition can be applied locally, involving only
information available on the current lattice site. We meet this need by
describing in detail how to transfer the approach suggested by Zou and He to a
D3Q19 lattice. The boundary condition acts locally, is independent of the
details of the relaxation process during collision and contains no artificial
slip. In particular, the case of an on-site no-slip boundary condition is
naturally included. We test the boundary condition in several setups and
confirm that it is capable to accurately model the velocity field up to second
order and does not contain any numerical slip.Comment: 13 pages, 4 figures, revised versio
Quantitative analysis of numerical estimates for the permeability of porous media from lattice-Boltzmann simulations
During the last decade, lattice-Boltzmann (LB) simulations have been improved
to become an efficient tool for determining the permeability of porous media
samples. However, well known improvements of the original algorithm are often
not implemented. These include for example multirelaxation time schemes or
improved boundary conditions, as well as different possibilities to impose a
pressure gradient. This paper shows that a significant difference of the
calculated permeabilities can be found unless one uses a carefully selected
setup. We present a detailed discussion of possible simulation setups and
quantitative studies of the influence of simulation parameters. We illustrate
our results by applying the algorithm to a Fontainebleau sandstone and by
comparing our benchmark studies to other numerical permeability measurements in
the literature.Comment: 14 pages, 11 figure
Inertial migration of oblate spheroids in a plane channel
We discuss an inertial migration of oblate spheroids in a plane channel,
where steady laminar flow is generated by a pressure gradient. Our lattice
Boltzmann simulations show that spheroids orient in the flow, so that their
minor axis coincides with the vorticity direction (a log-rolling motion).
Interestingly, for spheroids of moderate aspect ratios, the equilibrium
positions relative to the channel walls depend only on their equatorial radius
. By analysing the inertial lift force we argue that this force is
proportional to , where is the polar radius, and conclude that the
dimensionless lift coefficient of the oblate spheroid does not depend on ,
and is equal to that of the sphere of radius .Comment: 7 pages, 8 figure
Tensorial slip of super-hydrophobic channels
We describe a generalization of the tensorial slip boundary condition,
originally justified for a thick (compared to texture period) channel, to any
channel thickness. The eigenvalues of the effective slip length tensor,
however, in general case become dependent on the gap and cannot be viewed as a
local property of the surface, being a global characteristic of the channel. To
illustrate the use of the tensor formalism we develop a semi-analytical theory
of an effective slip in a parallel-plate channel with one super-hydrophobic
striped and one hydrophilic surface. Our approach is valid for any local slip
at the gas sectors and an arbitrary distance between the plates, ranging from a
thick to a thin channel. We then present results of lattice Boltzmann
simulations to validate the analysis. Our results may be useful for extracting
effective slip tensors from global measurements, such as the permeability of a
channel, in experiments or simulations.Comment: 12 pages, 7 figure
Simulation of Claylike Colloids
We investigate properties of dense suspensions and sediments of small
spherical silt particles by means of a combined Molecular Dynamics (MD) and
Stochastic Rotation Dynamics (SRD) simulation. We include van der Waals and
effective electrostatic interactions between the colloidal particles, as well
as Brownian motion and hydrodynamic interactions which are calculated in the
SRD-part. We present the simulation technique and first results. We have
measured velocity distributions, diffusion coefficients, sedimentation
velocity, spatial correlation functions and we have explored the phase diagram
depending on the parameters of the potentials and on the volume fraction.Comment: 20 pages, 14 figure
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