Management of Merino weaners for optimum production

Sheep mortality during the first year of life is a large problem on many farms and poses a significant animal welfare issue for Australian agriculture. Post weaning mortality is estimated to cost the Australian sheep industry more than $89 million annually through reduced income, poor productivity and increased management expenses (Sackett et al. 2006). A high mortality rate among weaners reduces the number of surplus animals available for sale and the number of potential breeding replacements. This, in turn, affects the selection intensity for desirable traits and the flock’s rate of genetic improvement. Ill thrift and poor growth of weaner sheep during their first year can reduce wool and meat production as well as the weaner’s reproductive performance at first joining.https://researchlibrary.agric.wa.gov.au/bulletins/1200/thumbnail.jp

An examination of ethical attitudes towards wild pig (Sus scrofa) toxicants in the United States

This research aims to understand ethical attitudes of the U.S. public towards the use of a toxicant to control wild pigs (Sus scrofa), a destructive invasive species whose population growth is proving difficult to control through conventional management methods. Using a nationwide self-administered survey with 2,186 completed and returned questionnaires, we found that among six different lethal control methods, toxicant usage was the only method that a majority of respondents (51%) found to be unethical, with no significant differences between rural and urban respondents or between respondents from counties with wild pigs and counties where the species is absent. The primary concerns of respondents were collateral harm to other animals (33%) and possible pain and suffering of wild pigs (13%). This research suggests that the introduction of a wild pig toxicant in the U.S. could face significant opposition, particularly if the public’s concerns highlighted in this study are not well understood and addressed in product development and outreach

FROM ONE CORPORATION TO ANOTHER: THE IMPACT OF THE 2018 TCJA ON DIVIDEND PAYMENTS

Prior to 2018, foreign-source dividend income paid to a U.S. corporate shareholder was not deductible. For any foreign-source dividends, the U.S. corporate shareholder was only entitled to a foreign tax credit. The dividends received deduction, outlined in I.R.C. §§ 243 and 245, applies only to U.S.-source dividend income. As part of the 2018 Tax Cuts and Jobs Act (“the TCJA”), Congress added a new provision, I.R.C. § 245A, allowing U.S. corporate shareholders to claim a deduction for foreign-source dividends. The changes do not stop with foreign-source dividends. U.S.-source dividends were also impacted by the TCJA. This paper will address the overall changes that have occurred with the taxation of dividends under the TCJA using examples to illustrate the pre versus post Act impact

Understanding sociotechnical action: an introduction to the special issue.

No abstract available. Item is Editorial preface to special issue

Prospective Teachers\u27 Use of Representations in Solving Statistical Tasks with Dynamic Statistical Software

This study examined a random stratified sample (n=62) of prospective teachers\u27 work across eight institutions on three tasks that utilized dynamic statistical software. Our work was guided by considering how teachers may utilize their statistical knowledge and technological statistical knowledge to engage in cycles of investigation. Although teachers did not tend to take full advantage of dynamic linking capabilities, they utilized a large variety of graphical representations and often added statistical measures or other augmentations to graphs as part of their analysis

A hierarchical model of transcriptional dynamics allows robust estimation of transcription rates in populations of single cells with variable gene copy number

Motivation: cis-regulatory DNA sequence elements, such as enhancers and silencers, function to control the spatial and temporal expression of their target genes. Although the overall levels of gene expression in large cell populations seem to be precisely controlled, transcription of individual genes in single cells is extremely variable in real time. It is, therefore, important to understand how these cis-regulatory elements function to dynamically control transcription at single-cell resolution. Recently, statistical methods have been proposed to back calculate the rates involved in mRNA transcription using parameter estimation of a mathematical model of transcription and translation. However, a major complication in these approaches is that some of the parameters, particularly those corresponding to the gene copy number and transcription rate, cannot be distinguished; therefore, these methods cannot be used when the copy number is unknown. Results: Here, we develop a hierarchical Bayesian model to estimate biokinetic parameters from live cell enhancer–promoter reporter measurements performed on a population of single cells. This allows us to investigate transcriptional dynamics when the copy number is variable across the population. We validate our method using synthetic data and then apply it to quantify the function of two known developmental enhancers in real time and in single cells

Development of a minimal KASP marker panel for distinguishing genotypes in apple collections

Accurate identification of named accessions in germplasm collections is extremely important, especially for vegetatively propagated crops which are expensive to maintain.  Thus, an inexpensive, reliable, and rapid genotyping method is essential because it avoids the need for laborious and time-consuming morphological comparisons.  Single Nucleotide Polymorphism (SNP) marker panels containing large numbers of SNPs have been developed for many crop species, but such panels are much too large for basic cultivar identification.  Here, we have identified a minimum set of SNP markers sufficient to distinguish apple cultivars held in the English and Welsh national collections providing a cheaper and automatable alternative to the markers currently used by the community.  We show that SNP genotyping with a small set of well selected markers is equally efficient as microsatellites for the identification of apple cultivars and has the added advantage of automation and reduced cost when screening large numbers of sample

Accelerometer and GPS Data to Analyze Built Environments and Physical Activity

Purpose: Most built environment studies have quantified characteristics of the areas around participants' homes. However, the environmental exposures for physical activity (PA) are spatially dynamic rather than static. Thus, merged accelerometer and global positioning system (GPS) data were utilized to estimate associations between the built environment and PA among adults. Methods: Participants (N = 142) were recruited on trails in Massachusetts and wore an accelerometer and GPS unit for 1-4 days. Two binary outcomes were created: moderate-to-vigorous PA (MVPA vs. light PA-to-sedentary); and light-to-vigorous PA (LVPA vs. sedentary). Five built environment variables were created within 50-meter buffers around GPS points: population density, street density, land use mix (LUM), greenness, and walkability index. Generalized linear mixed models were fit to examine associations between environmental variables and both outcomes, adjusting for demographic covariates. Results: Overall, in the fully adjusted models, greenness was positively associated with MVPA and LVPA (odds ratios [ORs] = 1.15, 95% confidence interval [CI] = 1.03, 1.30 and 1.25, 95% CI = 1.12, 1.41, respectively). In contrast, street density and LUM were negatively associated with MVPA (ORs = 0.69, 95% CI = 0.67, 0.71 and 0.87, 95% CI = 0.78, 0.97, respectively) and LVPA (ORs = 0.79, 95% CI = 0.77, 0.81 and 0.81, 95% CI = 0.74, 0.90, respectively). Negative associations of population density and walkability with both outcomes reached statistical significance, yet the effect sizes were small. Conclusions: Concurrent monitoring of activity with accelerometers and GPS units allowed us to investigate relationships between objectively measured built environment around GPS points and minute-by-minute PA. Negative relationships between street density and LUM and PA contrast evidence from most built environment studies in adults. However, direct comparisons should be made with caution since most previous studies have focused on spatially fixed buffers around home locations, rather than the precise locations where PA occurs