9 research outputs found
Amending the Uniform Commercial Code: How Will a Change in Scope Alter the Concept of Goods?
- Author
- Publication venue
- Washington University Open Scholarship
- Publication date
- 01/01/2004
- Field of study
Coronal Heating as Determined by the Solar Flare Frequency Distribution Obtained by Aggregating Case Studies
- Author
- Aaron James Holland
- Abdullah Jumana T.
- Abrams Jonathan M.
- Abrashoff Riley
- Acevedo Andres B.
- Acha Iker
- Acosta Daniela M. Meza
- Adam Megan M.
- Adams Dante Q.
- Adams Elena R
- Adams Kalvyn N
- Akbar Zainab A.
- Akruwala Ushmi H.
- Al-Ghazwi Adel
- AlAbbas Batool H.
- Alahmed Mohammed S.
- AlAwadhi Areej A.
- Albakr Mohammed A.
- Albalushi Yusef J.
- Albaum Jonathan
- Aldhamen Ahmed
- Ales Nolan
- Alesmail Mohammad
- Alhabeeb Abdulelah
- Alhamli Dania
- AlHarbi Yazeed A.
- Alhuseini Isehaq
- Alkaabi Suhail
- Alkhezzi Tameem
- Alkubaisi Mohamed
- Allanqawi Nasser
- Allsbrook Martin
- Almohsen Yousef A.
- Almquist Justin Thomas
- Alnaji Teeb
- Alnasrallah Yousef A
- Alonzi Nicholas
- Alosaimi Meshal
- Alqabani Emeen
- Alrubaie Mohammad
- Alsinan Reema A.
- Altenbern Ava L.
- Altokhais Abdullah
- Alyami Saleh A.
- Ameijenda Federico
- Amer Hamzi
- Amos Meggan
- Anderson Hunter J.
- Andrew Carter
- Andringa Jesse C
- Angwin Abigail
- Aradhya Arvind J.
- Aramians Andrew
- Arango Camila Villamil
- Archibald Jack. W.
- Arias-Robles Brian A.
- Aryan Maryam
- Ash Kevin
- Astalos Justin
- Atchley-Rivers N. S.
- Augenstein Dakota N.
- Austin Bryce W.
- Avula Abhinav
- Aycock Matthew C.
- Baflah Abdulrahman A.
- Balaji Sahana
- Balajonda Brian
- Balcer Leo M
- Baldwin James O.
- Banda David J
- Bard Titus
- Barmore Abby
- Barnes Grant M.
- Barnhart Logan D. W.
- Barone Kevin M.
- Bartman Jessica L.
- Bassel Claire
- Bastias Catalina S
- Bat-Ulzii Batchimeg
- Batra Jasleen
- Battist Lexi
- Bay Joshua
- Beach Simone
- Beard Sara
- Beato Quinn I
- Beattie Ryan
- Beatty Thomas
- Beauprez Jacob N.
- Beck Lily
- Beck M. G.
- Becker Simone E.
- Behr Braden
- Behrer Timothy A.
- Beijer Joshua
- Belei Brennan J.
- Belknap Annelene L.
- Bell Aislyn
- Bence Caden
- Benke Evan
- Berhanu Naomi
- Berriman-Rozen Zachary D.
- Bertuccio Chrisanna
- Berv Owen A.
- Biediger Blaine B.
- Biehle Samuel J
- Billig Brennen
- Billingsley Jacob
- Billman Jayce A.
- Biron Connor J.
- Bisacca Gabrielle E.
- Blake Cassidy A.
- Blandon Guillermo
- Blevins Olivia
- Blouin Ethan
- Bodzianowski Michal
- Boeyink Taylor A.
- Bondar Matthew
- Bone Lauren
- Bonilla Alberto Espinosa de los Monteros
- Borelli William T
- Borgerding Luke R.
- Bowen Troy
- Boyer Aidan
- Boyer Christine
- Boyle Aidan P.
- Boyne Tom
- Branch Donovan
- Brecl Ariana E.
- Brennan David J.
- Brimhall Alexander J
- Brockman Jennifer L.
- Brookins Sarah
- Brown Cameron L.
- Brown Gabriel T.
- Brown Ryan
- Brownlow Jordi
- Brumage-Heller Grant
- Brumley Preston J.
- Bryan Samuel
- Brzostowicz A.
- Buhamad Maryam
- Bullard-Connor Gigi
- Bunsow J. R. Ramirez
- Burns Annemarie C.
- Burritt John J.
- Burton Nicholas David
- Burton Taylor
- Busch Celeste
- Butler Dylan R.
- Buxton B. W.
- Cabbage Carter C.
- Cage Breonna
- Cahn Jackson R.
- Cai Yijian
- Campbell Andrew J
- Canales Braden P.
- Cancio Alejandro R.
- Carey Luke
- Carillion Emma L.
- Carpender Michael Andrew
- Carpenter Emily
- Chadda Shivank
- Chambers Paige
- Chanders Jasey
- Chandler Olivia M.
- Chang Ethan C.
- Chaparro David
- Chapman Logan T.
- Chapman Mitchell G.
- Chavali S.
- Chavez Luis
- Cheang Nathan M.
- Chen Judy
- Chen Kevin
- Chen Lily
- Chen Sam
- Chhetri Jenisha
- Chiles Bradyn
- Chizmar Kayla M.
- Christiansen Katherine E
- Cisne Nicholas A.
- Cisneros Alexis
- Clark David B.
- Clarke Evelyn
- Clarkson Peter C
- Clausi Alexis R.
- Cochran Brooke
- Coe Ryan W.
- Coleman-Plante Aislinn
- Colleran Jake R.
- Colleran Zachary
- Collier Curran
- Collins Jack C.
- Collins Nathaniel A.
- Collins Sarah
- Colozzi Michael
- Colter Aurora
- Cone Rebecca A.
- Conroy Thomas C.
- Conti Reese
- Contizano Charles J.
- Cool Destiny J.
- Cooper Nicholas M.
- Corbitt Jessica S
- Courtney Jonas
- Courtney Olivia
- Cox Corben L.
- Craig Wilmsen B.
- Creany Joshua B.
- Crews Anastasia
- Crocker K. A.
- Croteau A. J.
- Crow Christian J.
- Cruse Zoe
- Cruz Avril
- Curnow Tyler L.
- Current Hayden
- Curry Riley T.
- Cutler Libby
- Cyr Aidan St.
- Dabberdt Frederick M.
- Daboub Johnston
- Damgaard Olivia
- Das Swagatam
- Davis Emma A. B.
- de La Beaujardiere Tristan
- DeBarros Elyse
- Deel Sean
- Del Foco Leonardo
- Delasantos Megan E.
- Deng Tianyue
- Derwin Zachary
- Desai Om
- Dewey Kai
- Dias John S.
- Dice Kenzie A.
- Dick R.
- Dicken Cyrus A.
- Dietrick Henry
- Dinser Alexis M.
- Dixon Alyssa M.
- Dixon Thomas J.
- Do Helen C.
- Doan Chris H
- Doane Connor
- Dodrill Joshua
- Doermer Timothy
- Dominguez J.
- Dominguez Lizbeth Montoya
- Domke Emerson N.
- Doran Caroline R.
- Dorr Jackson A.
- Dorricott Philip
- Dresdner Danielle C.
- Driscoll Kailer H.
- Driscoll Michael
- Duncan Sheridan J.
- Dunlap Christian
- Dunn Gabrielle M.
- Duong Tien Q.
- Dupeyron Tomi Oshima
- Dvorak Peter
- East Andrew
- East Andrew N.
- Edwards Bree
- Ehrlich Lauren
- Elbashir Sara I.
- Engelhardt Rasce
- Engelstad Jacob
- England Colin
- Enrich Andrew
- Erickson Abbey
- Erickson Benjamin
- Erikson James W.
- Evans Nathan
- Ewing Calvin A
- Eyeson Elizabeth A.
- Faber Ian
- Fails Avery M.
- Fauntleroy John T
- Fell Kevin
- Feng Zitian
- Fenwick Logan D.
- Feoktistov Nikita
- Fife Ryann
- Figueirinhas John Alfred D.
- Fisch Jean-Paul
- Fischer Emmalee
- Fischer-White Jules
- Fitton Aidan F.
- Fix Alexander
- Flackett Lydia
- Flores Fernando
- Floyd Aidan
- Folarin Adeduni
- Forbes Aidan E.
- Fortino Elise
- Fougere Benjamin L.
- Fowler Alexandra A.
- Fox Margaret
- French James M.
- French Katherine V.
- Frick Florian G.
- Fuchs Calvin R.
- Fuhrman Bethany E. S.
- Furney Sebastian
- Gabir Moutamen
- Galarraga Gabriela
- Gale Skylar
- Ganesan Koushik
- Gapin Keala C.
- Garscadden A. J.
- Gasser Rachel
- Gayou Lily
- Gearhart Emily E.
- Geerdts T. R.
- Geisman Jane
- Geneser Julianne R.
- Genne SL
- Gentile Julia G
- Gentry Eleanor
- George Jacob D.
- Georgiades Nathaniel James
- Gerhardstein Phillip
- Gersabeck Clint
- Ghaith Bandar Abu
- Ghiassi Dorsa
- Giebner B. C.
- Gilmartin Dalton
- Gilpatrick Connor B.
- Gjini Michael
- Golden Olivia
- Golding Nathan T.
- Goldsberry C. A.
- Gomez Angel A.
- Gomez Angel R.
- Gopalakrishnan Sean
- Gopalani Mariam
- Gotlib Nicholas
- Graham Alaina S.
- Gray Michael J
- Gregory Alannah H.
- Gregory Joshua A.
- Grell Kristyn
- Griego Justus
- Griffin Kyle J.
- Griffin Nicholas F.
- Guerrero Matt
- Gunderson Nicole
- Guo Mutian
- Gustavsson E. R.
- Hach Grace K.
- Haile L. N.
- Haines Jessica
- Hale Jack J. Mc
- Hales Ryder Buchanan
- Haley Mark S.
- Hall Jacqueline L.
- Hamilton Sean R.
- Han Soonhee
- Hand Tyler
- Hanley Luke C.
- Hansen Connor M
- Hansen Joshua A.
- Hansson Jonathan
- Hao Tony Yunfei
- Haratsaris Nicholas
- Hardie Isabelle
- Hardwick Dillon F.
- Hares Cameron T.
- Harris Coyle M.
- Harris Logan Swous
- Hart Omer
- Hashiro Kyle
- Hattendorf Elsie
- Haubrich Calder
- Hawat Elijah
- Hayrynen Griffin A.
- Heintz Danielle A.
- Hellweg Tim
- Hernandez Angel
- Herrera Emanuel
- Herrington Robert N.
- Herwig Tim
- Hesse Troy M.
- Hiatt Quinn
- Hibbard Lea Pearl
- Hicks Andrew J.
- Hicks Imari R.
- Highhouse Nigel
- Hildebrand Annalise K.
- Hill Hallie
- Hill Paula
- Hintsa Evan
- Hirschmann Anna E.
- Hitt Travis
- Ho Ella
- Hoang Thi D
- Hoff Isabelle J.
- Hoffman Alex
- Hogen Blake A.
- Horne Linda
- Horning Thomas M.
- Houck Timothy J
- House Jr. Tony A.
- Howell Noah H.
- Hrudka E. M.
- Hu J.
- Huang Chenqi
- Huang Jianyang
- Huang Shancheng
- Hudson Nathan C.
- Hudson Zachary A.
- Huebsch Tyler J.
- Hull Owen
- Hunter Samuel C
- Husted Troy
- Hutabarat Abigail P.
- Huynh Leslie
- Idoine Yolande
- Ingram Julia A.
- Iovan Taro
- Isert Samuel A.
- Jacobsen Thomas
- Jaimes Alan A
- Jameson Connor
- Jarriel J. R.
- Jarvis Sam
- Jenkins Josh
- Jensen Alexander V.
- Jeong Jacob
- Jeseritz Luke A.
- Jesse Trevor
- Ji Soo Yeun
- Jiang Yufan
- Jin Yan
- Johnson Matthew
- Johnson Owen
- Johnson Sawyer
- Johnston Braedon Y.
- Johnston Julia
- Jones M. R.
- Jones Olivia M.
- Jourabchi Tara
- Juels Parker
- Kainz Sabrina J. H. T.
- Kaiser Emily
- Kallemeyn Nicolas Ian
- Kalmus Madison H.
- Kalra Etash
- Kamenetskiy Margaret
- Kanokthippayakun Jeerakit
- Kapla Shaun D.
- Karsh Brennan J.
- Keating Caden J.
- Kelley Michael P.
- Kelley Morgan A.
- Kelly Christopher M
- Kelly James
- Kelly Nicholas
- Kelly Teagan
- Kennedy Abigail
- Kennedy Cayla J.
- Kennedy Forrest
- Kennedy Kellen
- Kerr-Layton Liana
- Ketterer Marilyn
- Khan Ibraheem A.
- Khan Usman
- Khanal Sapriya
- Kiechlin Jack L.
- Killian Dominic
- Kim Brian T.
- Kim Jake
- Kim Kevin
- Kim Matthew M.
- Kimlicko Aspen
- Kipp Isabel M
- Kirkpatrick Hunter B.
- Kissner Natalie
- Kite Emily R.
- Kleinhaus Olivia R.
- Knott Philip Whiting
- Koch Will
- Koenig Greta
- Koke Emily
- Kokes Thomas
- Kothamdi Yash S.
- Krajnak Zack
- Kresek Zoe M.
- Kriegman Dylan
- Kritzberg Jake E.
- Krueger Davis J.
- Kubiak Bartlomiej
- Kuehl Kirsten
- Kuester Chrisanne
- Kuiper Nicolas A.
- Kumar Aman Priyadarshi
- Kuybus Connor
- Kwiatkowski Daniel
- Lacjak Kevin
- LaFemina Quintin Y.
- Lahmers Kyle
- Lam Antonia
- Landrey Kalin
- Lantz Maxwell B.
- Larter Zachary
- Lau Benjamin P.
- Lauzon Megan
- Lawlor Rian
- Learned Tyler
- Lee Adrianna J.
- Lee Alexis Ying-Shan
- Lee Christian J
- Lee E. C.
- Lee Junwon
- Lee Justin
- Lee Nathaniel F.
- Leiker Linzhi
- Lengerich Dylan
- Leoni Cecilia
- Lewandowski H. J.
- Lezak Adrienne R.
- Li David Y.
- Li Isaac
- Liao Ryan Z.
- Linders Bridget
- Linger Morgan I
- Linnane Katherine B.
- Lippincott Sam
- Lister Barrett
- Litton Shelby D
- Liu Haixin
- Liu Nianzi
- Liu Steven Y.
- Logan Timothy W.
- Londres Nathan
- Lonergan Mia C.
- Lookhoff Emily
- Loomis N. E.
- Lopez Christian
- Lordi Noah
- Loring Justin
- Lucca Jeffrey
- Lukianow Dax
- Luo Zheng
- MacDonald William
- Madonna Claire A.
- Madsen Kasey O.
- Maksimuk Tiffany E.
- Mallory Macguire
- Malone Ryan A.
- Maly Blake
- Manzanares Xander R.
- Maravi Aimee S.
- Marcus Serafima M.
- Marikar Nasreen
- Marquez Josie A.
- Marquez Mathew J.
- Marsh Lauren
- Marsh Toni
- Martin Logan S.
- Martinez Alexa M.
- Martinez Hazelia K.
- Martinez Jose R.
- Martyr Cara
- Mason James Paul
- Masri Mirna
- Matessi Giorgio
- Mathavan Adam Izz Khan Mohd Reduan
- Mathieson Randi M.
- Mathur Kabir P.
- Mauer Graham
- Mayer Victoria A.
- Mazzotta Liam
- McCammon Glen S.
- McConvey Rowan
- McCormick Tyler
- McCoy Andrew
- Mccurry Kyle
- McEntee Kelleen
- McGarvey Meaghan V.
- McGill Riley M.
- McIntyre James K.
- McKemey Finbar K.
- McMorris Zane
- McMullan Jesse J.
- McQuaid Ella
- McVey Caden
- Medellin Mateo M.
- Medialdea Melissa
- Mehidic Amar
- Meillon Stella
- Meiselman-Ashen Jonah B.
- Mellett Sarah
- Menassa Dominic
- Mendez Citlali
- Mendoza-Anselmi Patricia
- Menke Riley
- Menon Thanmay S.
- Mesgina Sarah
- Mewhirter William J.
- Meyer Ethan
- Meyer Josephine C.
- Miften Aya M.
- Miles Ethan J.
- Miller Andrew
- Miller Joshua B.
- Millican Emily B.
- Millican Sarah J.
- Mills Dylan P.
- Minimo Josh
- Misener Jay H.
- Mitchell Alexander J.
- Mizzi Alexander Z.
- Molina-Saenz Luis
- Moll Hayden
- Moll Tyler S
- Montano Maximus
- Montoya Michael
- Monyek Eli
- Mora Jacqueline Rodriguez
- Morales Gavin
- Morales Genaro
- Morelock Annalise M.
- Morency Cora
- Moreno Angel J.
- Morgan Remy
- Moss Alexander P.
- Muckenthaler Brandon A.
- Mueller Alexander
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- Muniz Alexis A.
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- Murphy Maxwell J.
- Murphy Ryan C.
- Murrel Tyler
- Musgrave Andrew J.
- Myer Michael S.
- Nandu Kshmya
- Napoletano Elena R.
- Naqi Abdulaziz
- Narayan Anoothi
- Nasser Liebe
- Neeland Brenna K
- Nehring Molly
- Nelson Emma E
- Nelson Maya LI
- Nguyen Khoa D
- Nguyen Lena
- Nguyen Lena P.
- Nguyen Leonardo
- Nguyen Valerie A.
- Norden Kelso
- Norris Cooper
- Nunes-Valdes Dario
- Nussbaum Rosemary O.
- O'neill Ian
- O'Sullivan Cian
- Oakes S. H.
- Odbayar Anand
- Ogle Caleb
- Oishi-Holder Sean
- Olguin Nicholas
- Oliver Kristin A.
- Olson Nathaniel P.
- Ong Jason
- Opp Elena N.
- Orbidan Dan
- Oros Ryan
- Ort Althea E.
- Ortiz Jorge L Ramirez
- Osborn Matthew
- Osborne Andrew
- Osogwin Austin
- Otto Grant
- Oudakker Jessica
- Overchuk Igor
- Padgette Hannah M.
- Padilla Jacqueline
- Palizzi Mallory
- Palmgren Madeleine L.
- Palos Adler
- Pan Luke J.
- Parker Nathan L.
- Parker Sasha R.
- Parkinson Evan J.
- Parulekar Anish
- Pastor Paige J.
- Patel Akhil
- Patel Kajal
- Patel Neil S.
- Patterson Alyx
- Patti Samuel
- Patton Catherine
- Payne Genevieve K.
- Payne Matthew P.
- Pearl Harrison M.
- Peck Courtney
- Pedersen Alexander J.
- Pellatz Nick
- Pelster Lily M.
- Peou Munisettha E.
- Perez Freddy
- Perez J. S.
- Pesce Anneliese
- Petersen Audrey J.
- Peterson B.
- Petric Romeo S. L.
- Pettine Joshua
- Phalen Ethan J.
- Pham Alexander V.
- Phan Denise M.
- Pherigo Callie C
- Phillips Justin
- Phillips Lance
- Phommatha Krista
- Pietras Alex
- Pine Tawanchai P.
- Pitsuean-Meier Sedique
- Pitten John
- Pixley Andrew M.
- Plantz Will
- Plummer William C.
- Plutt Kaitlyn E.
- Plzak Audrey E.
- Pohle Kyle
- Polikoff Hyden
- Pollard Matthew
- Polly Madelyn
- Porter Trevor J.
- Price David
- Price Nicholas K.
- Prinster Gale H.
- Propper Henry Austin
- Quarderer Josh
- Quinn Megan S.
- Quinonez Oliver
- Quispe Devon
- Ragsdale Cameron
- Rahn Anna L.
- Rakhmonova M.
- Ralapanawe Anoush K
- Ramachandra Nidhi
- Ramirez Ariana C.
- Ramirez Nathaniel
- Ramirez Sacha
- Randolph Parker
- Ranjan Anurag
- Rankin Frederick C
- Rapaport Sarah Grace
- Ratajczyk Nicholas O
- Ray Mia G. V.
- Reagan Brian D.
- Recchia John C.
- Reddy Brooklyn J.
- Reed Charlie
- Reed Joseph
- Reeves Justin
- Reh Eileen N.
- Reyna Andrea B.
- Reynolds Alexander
- Reynolds Hope
- Rippel Matthew
- Rivas Guillermo A.
- Rives Anna Linnea
- Robert Amanda M.
- Robertson Samuel M.
- Rodgers Maeve
- Rojec Stewart
- Romero Andres C.
- Rosasco Ryan
- Rossman Beth
- Rotter Michael
- Rounsefell Tyndall
- Rouse Charlotte
- Routledge Allie C.
- Roy Marc G.
- Roy Zoe A.
- Ruger Ryan
- Ruggles-Delgado Kendall
- Rule Ian C.
- Rumley Madigan
- Runyon Brenton M.
- Ruprecht Collin
- Russell Bowman
- Russell Sloan
- Ryder Diana
- Saeb David
- Salazar J.
- Salazar Violeta
- Salcido-Alcontar JR Antonio
- Saldi Maxwell
- Salgado Jose A.
- Salindeho Adam D.
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- Sanchez-Sanchez Gustavo
- Sarfaraz Darian
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- Schaller Marcus T.
- Scheck Benjamin T.
- Schlenker Jared A. W.
- Schofer Matthew J
- Schubert Stephanie H.
- Schultze Courtney
- Schumacher Grace K
- Seglem Kasper
- Serio Lauren
- Seux Octave
- Shahba Hannan
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- Sharma Shajesh
- Shaver Nathan
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- Shelby Emma
- Shelchuk Grace
- Sheldrake Tucker
- Sherry Daniel P.
- Shi Kyle Z.
- Shields Amanda M.
- Shin Kyungeun
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- Shockley Michael C.
- Shoha Dominick
- Shortman Jadon
- Shuttleworth Mitchell
- Sibrell Lisa
- Sickler Molly G.
- Siles Nathan
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- Simmons Conor
- Simone Anna
- Simone Dylan M.
- Singh Maya A.
- Singh Savi
- Sinkovic Madeline
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- Smith Corey
- Smith Elena K.
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- Smith Trevor J
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- Soon Caitlin
- Spangler Ava A
- Spicer Benjamin C.
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- Steinsberger Christopher H.
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- Sulaiman S. A
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- Sundell M. E.
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- Taylor Liam C.
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- Tressler Judah
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- Trunko Benjamin L.
- Truong Joshua K.
- Tucker Julia
- Umbricht Thomas D
- Uphoff C. H.
- Upthegrove Zachary T.
- Vadayar Shreenija
- Valencia Whitney
- Vallery Mia M.
- Van Anne Gabreece
- VanEtten Eleanor
- Vann John D.
- Varela Ilian
- Vassilyev Alexandr
- Vaver Nicholas J.
- Velamala Anjali A.
- Vendetti Evan
- Venegas Nancy Ortiz
- Vepa Aditya V.
- Vess Marcus T.
- Veta Jenna S.
- Victory Andrew
- Vinson Jessica
- Visal Aseem
- Vogel Connor Maklain
- von Peccoz Charles B. Beck
- Von Reich Ferin J.
- Wagoner Michaela
- Wallace Logan
- Wallace Steven P.
- Waller Caroline
- Wang Chaoran
- Wang Hongda
- Wang Jiawei
- Warble Keenan
- Ward-Chene N. R. D.
- Watson James Adam
- Weber Robert J.
- Wegner Aidan B.
- Weigand Anthony A
- Weiner Amanda M.
- Werth Alexandra
- West Ayana
- West Colin G.
- Wexler Ethan Benjamin
- Wheeler Nicola H.
- White Jamison R.
- White Oliver S.
- White Zachary
- Whittall Lloyd C.
- Wickenden Evan
- Wilcove Isaac
- Wilkinson Blake C.
- Willard John S.
- Williams Abigail K.
- Williams Sajan
- Wilson Connor B.
- Wilson Evan M.
- Wilson John
- Wilson Orion K.
- Wilson Timothy R.
- Witkoff Briahn
- Wolfe Aubrey M.
- Wolle Jackson R.
- Wood Travis M.
- Woodard Aiden L.
- Woodraska Donald L.
- Wootten Katelynn
- Wu Mengyu
- Xiao Catherine
- Yang Jianing
- Yang Zhanchao
- Yegovtsev Nikolay
- Young Isabel
- Young Trenton J.
- Youngblood Allison A.
- Zenner Thomas
- Zhang Jiaqi
- zhang Jinhua
- Zhao Noah Y.
- Zhao Tiannie
- Zhao Tianwei
- Zhou Chongrui
- Ziebold Josh J
- Ziegler Lucas J.
- Zimmermann Ingrid H
- Zygmunt James C.
- Publication venue
- 'American Astronomical Society'
- Publication date
- 09/05/2023
- Field of study
Flare frequency distributions represent a key approach to addressing one of
the largest problems in solar and stellar physics: determining the mechanism
that counter-intuitively heats coronae to temperatures that are orders of
magnitude hotter than the corresponding photospheres. It is widely accepted
that the magnetic field is responsible for the heating, but there are two
competing mechanisms that could explain it: nanoflares or Alfv\'en waves. To
date, neither can be directly observed. Nanoflares are, by definition,
extremely small, but their aggregate energy release could represent a
substantial heating mechanism, presuming they are sufficiently abundant. One
way to test this presumption is via the flare frequency distribution, which
describes how often flares of various energies occur. If the slope of the power
law fitting the flare frequency distribution is above a critical threshold,
α=2 as established in prior literature, then there should be a
sufficient abundance of nanoflares to explain coronal heating. We performed
>600 case studies of solar flares, made possible by an unprecedented number
of data analysts via three semesters of an undergraduate physics laboratory
course. This allowed us to include two crucial, but nontrivial, analysis
methods: pre-flare baseline subtraction and computation of the flare energy,
which requires determining flare start and stop times. We aggregated the
results of these analyses into a statistical study to determine that α=1.63±0.03. This is below the critical threshold, suggesting that Alfv\'en
waves are an important driver of coronal heating.Comment: 1,002 authors, 14 pages, 4 figures, 3 tables, published by The
Astrophysical Journal on 2023-05-09, volume 948, page 7
An international observational study to assess the impact of the Omicron variant emergence on the clinical epidemiology of COVID-19 in hospitalised patients
- Author
- A M Udara Lakshan Attanyake
- Aasiyah Rashan
- Aasiyah Rashan
- Abby Hurd
- Abdulrahman Al-Fares
- Abhishek Dasgupta
- Abigail Beane
- Adrian Streinu-Cercel
- Adrienne Chan
- Aidan Burrell
- Alan Hartman
- Alberto Uribe
- Alejandro Martin-Quiros
- Alejandro Martín-Quiros
- Alejandro Martín-Quiros
- Aleksander Rygh Holten
- Alexander J Mentzer
- Alfredo Antonio Chetta
- Ali Abbas
- Alicia Gonzalez
- Alison M Meynert
- Alistair Nichol
- Allison McGeer
- Ama Kwakyewaa Bedu-Addo
- Amanda Corley
- Amanda Rojek
- Amanda Rojek
- Amar Bhatt
- Amna Faheem
- Amy Lester-Grant
- Ana Aroca
- Ana da Silva Filipe
- Ana Freitas Ribeiro
- Anais Rampello
- Anant Kataria
- Anca Streinu-Cercel
- Anca Streinu-Cercel
- Anders Benjamin Kildal
- Anders Kildal
- Anders Tveita
- Andra-Maris Post
- Andrea Angheben
- Andrea Ticinesi
- Andrea Villoldo
- Andreas Lind
- Andrew Dagens
- Andrew Letizia
- Andy Law
- Angela Alberti
- Anja Grosse Lordemann
- Anna Berenguera
- Anne Margarita Dyrhol-Riise
- Anne McCarthy
- Anne-Marie Guerguerian
- Annemarie B Docherty
- Antonia Ho
- Antonio Arcadipane
- Arabella Fahy
- Ardiyan Apriyana
- Arjen M Dondorp
- Asgar Rishu
- Asgar Rishu
- Astarini Hidayah
- Audrey Dubot-Pérès
- B P Sanka Ruwan Sri Darshana
- Barbara Wanjiru Citarella
- Barbara Wanjiru Citarella
- Beathe Kiland Granerud
- Beatrice Alex
- Benjamin Bach
- Bianca Boxma
- Birgitte Stiksrud
- Bounthavy Chaleunphon
- Bountoy Sibounheuang
- Brenda Molloy
- Brenda Reeve
- Brigid Flynn
- Bronner P Gonçalves
- Bronner P Gonçalves
- Budha Charan Singh
- Cameron J Fairfield
- Carlo Ferrari
- Carlos Cañada Illana
- Carlotta Mutti
- Caroline Martins Rego
- Caroline Mudara
- Carrol Gamble
- Cassidy Codan
- Caterina Caminiti
- Catherine A Shaw
- Catherine Blier
- Catherine Marquis
- Cecilia Canepa
- Ceila Maria Sant Ana Malaque
- Chamira Kodippily
- Charlotte Summers
- Chiara Vitiello
- Chloe Donohue
- Chris Kandel
- Christel Arnold-Day
- Christiana Kartsonaki
- Christiana Kartsonaki
- Christl A Donnelly
- Christophe Fraser
- Christopher A Green
- Clare Jackson
- Clark D Russell
- Claudia Bianco
- Claudia Figueiredo-Mello
- Claudia Figueiredo-Mello
- Claudia Montes
- Colin McArthur
- Cornelius Rau
- Dafsah Juzar
- Dag Henrik Reikvam
- Dan Meyer
- Daniel Haber
- Daniel Marino
- Danoy Chommanam
- David Bellemare
- David L Robertson
- David Maslove
- David S Y Ong
- David S Y Ong
- David Stuart
- David Thomson
- Debby Bogaert
- Deepali Kumar
- Demetrios Kutsogiannis
- Derbrenn OConnor
- Diego Fernando Bautista Rincon
- Diego Franch-Llasat
- Diptesh Aryal
- Diptesh Aryal
- Dori-Ann Martin
- Dounia Bouhmani
- Edel Meaney
- Eder Caceres
- Efstathia Mihelis
- Egle Saviciute
- Elaine McPartlan
- Elena Molinos
- Elena Ranza
- Elizabeth A Ashley
- Ellen Shadowitz
- Else Quist-Paulsen
- Eman Al Qasim
- Emily Neumann
- Emma C Thomson
- Emmanuelle A Dankwa
- Emmanuelle Denis
- Enrico Adriano
- Esteban Garcia-Gallo
- Eva Miranda Marwali
- Evert-Jan Wils
- Evert-Jan Wils
- Ewen M Harrison
- Ewen M Harrison
- Federica Fogliazza
- Federica Garofalo
- Felwa Bin Humaid
- Ferran Roche-Campo
- Fiona Griffiths
- Francesca Carlacci
- Francesco Rausa
- Francisca Adewhajah
- Frank Manetta
- Frank Olav Pettersen
- Franklina Korkor Abebrese
- François Lamontagne
- François Martin Carrier
- François Martin Carrier
- Fredrik Müller
- Frédérick D'Aragon
- G Argin
- Gail Carson
- Gail Carson
- Gamage Dona Dilanthi Priyadarshani
- Gary Leeming
- Gary Schwartz
- Gayle Carney
- Gennaro Martucci
- Georgios Pollakis
- Geraldine Goco
- Gianluigi Li Bassi
- Giorgio Economopoulos
- Giovanna Occhipinti
- Giovanna Panarello
- Giuseppe Maglietta
- Gloria Crowl
- Graham S Cooke
- Gry Kloumann Bekken
- Gyan Sandhu
- Haixia Shi
- Hannah Habraken
- Hannah Keane
- Hannah Marrinan
- Hayley Hardwick
- Hazel Bergin
- Heidi Dalton
- Hem Paneru
- Henrique Mateus Fernandes
- Himasha Muvindi
- Himed Musaab
- Hubert Tessier-Grenier
- Husna Begum
- Iam Claire E Sarmiento
- Ignacio Martin-Loeches
- Ilaria Valzano
- Imrana Khalid
- Indrek Rätsep
- Ingrid G Bustos
- Inês Carqueja
- Irene Bandoh
- ISARIC Clinical Characterisation Group
- J Kenneth Baillie
- J Kenneth Baillie
- Jacky Y Suen
- Jake Dunning
- Jake Dunning
- James Joshua Douglas
- James Joshua Douglas
- James Lee
- James Scott-Brown
- James Vickers
- Jan Cato Holter
- Janet Diaz
- Janet Harrison
- Janet Liang
- Janet T Scott
- Janice Caoili
- Janice Caoili
- Jaques Sztajnbok
- Jeff Powis
- Jennifer Lee
- Jess Gibson
- Jia Wei
- Jillian Deacon
- Jo Dalton
- Joan Gómez-Junyent
- Joan Gómez-Junyent
- Joanne Downey
- Joaquín Baruch
- Joaquín Baruch
- John Beca
- John F Fraser
- John Marshall
- Johnny McKeown
- Jonathan Bitton
- Jordi Rello
- José Antonio Lepe
- José Ernesto Vidal
- João Camões
- Juan Fiorda
- Juan Pablo Horcajada
- Judit Villar
- Julia Garcia-Diaz
- Julian Chica
- Kalynn Kennon
- Kamal Abu Jabal
- Karl Erik Müller
- Karolina Krawczyk
- Kate Ainscough
- Kathy Brickell
- Katie O'Hearn
- Kenneth A McLean
- Kevin Katz
- Kizy Sanchez de Oliveira
- Kristian Tonby
- Kusum Menon
- Lance C W Turtle
- Lars Hegelund
- Lars Heggelund
- Latsaniphone Bountthasavong
- Laura Feeney
- Laura Marsh
- Laura Merson
- Laura Merson
- Laura Patrizi
- Laveena Munshi
- Leanne Hays
- Leonardo Salazar
- Leonardo Salazar
- Liadain Reid
- Lina Morales Cely
- Linda Gail Skeie
- Linda O'Shea
- Lisa Norman
- Lisa Patterson
- Liv Hesstvedt
- Lorinda Essuman
- Lorna Murphy
- Louise Sigfrid
- Luca Sacchelli
- Lucian Durham
- Lucille Blumberg
- Luis Felipe Reyes
- Luis Felipe Reyes
- Luis Periel
- Lukas Arenz
- Madiha Hashmi
- Madiha Hashmi
- Mahdad Noursadeghi
- Malcolm G Semple
- Malcolm G Semple
- Mangala Narasimhan
- Manivanh Vongsouvath
- Maram Zahran
- Marco Echeverria-Villalobos
- Mare Pejkovska
- Margarite Grable
- Maria Angelica Rivera Nuñez
- Maria Donnelly
- Maria Lawrensia Tampubolon
- Maria Majori
- Maria Zambon
- Marianne Fraher
- Mariano Esperatti
- Marie Connor
- Marina Aiello
- Marina Lanza
- Mark G Pritchard
- Mark Pritchard
- Marlene Santos
- Martina Escher
- Mary Copland
- Massimo Palmarini
- Matteo Puntoni
- Matteo Rossetti
- Matthew Hall
- Matthew Hall
- Matthew Nelder
- Mayfong Mayxay
- Meera Chand
- Melissa Parker
- Mical Paul
- Michael Edelstein
- Michael Varrone
- Michaela Barnikel
- Michele Petrovic
- Michelle E Kho
- Michelle Girvan
- Michelle Smyth
- Mohd Basri Mat Nor
- Mohiuddin Shiekh
- Moirangthem Bikram Singh
- Moritz U G Kraemer
- Moses Siaw-Frimpong
- Muge Cevik
- Murray Dryden
- Murray Wham
- Musharaf Sadat
- Nashat Abu Salah
- Nathaniel Christy
- Netta Beer
- Nick Daneman
- Nicola Latronico
- Nicole White
- Nidyanara Castanheira
- Nina Jamieson
- Nora Fuentes
- Oana Sandulescu
- Obada Yousif
- Oleksa Rewa
- Ooyanong Phonemixay
- P G Ishara Udayanga
- Paa Kobina Forson
- Paddy Mallon
- Paolo Parducci
- Pathik Dhanger
- Patricia Fontela
- Patricia Gordon
- Patrick Archambault
- Patrizia Bonelli
- Patrizia Mammi
- Paul Klenerman
- Paul Tierney
- Paula Custodio
- Perren J Cobb
- Peter Daley
- Peter Doran
- Peter Horby
- Peter Horby
- Peter Kiiza
- Peter Openshaw
- Phil Gallagher
- Philippe Jouvet
- Phoebe Ampaw
- Phouvieng Douangdala
- Piero L Olliaro
- Piero L Olliaro
- Piret Sillaots
- Pompini Agustina Sitompul
- Pooja Varghese
- Prasan Kumar Panda
- Rachael McConnochie
- Rachael Parke
- Rajavardhan Rangappa
- Rajavardhan Rangappa
- Rajesh Mohan Shetty
- Rakesh Arora
- Rashan Haniffa
- Renata Barbalho
- Richard S Tedder
- Riinu Pius
- Rima Song
- Rob Fowler
- Robert A Fowler
- Roberta Cavalin
- Roberta Pisi
- Roberto Roncon-Albuquerque
- Robin Kobbe
- Romans Matulevics
- Rosario Maria Torres Santos-Olmo
- Ross Hendry
- Rumaisah Satyawati
- Rupert Higgins
- Ruth Lyons
- Ryan S Thwaites
- Sabina Mason
- Sadie Kelly
- Sally Shrapnel
- Samreen Ijaz
- Samuel Hinton
- Sandra Rossi
- Sanne Wesselius
- Santi Dewayanti
- Saptadi Yuliarto
- Sara Clohisey
- Sarah E McDonald
- Sarah Moore
- Saye Khoo
- Scott Pharand
- Sebastian Vencken
- Seán Keating
- Shaikh Sharjeel
- Sharma Keshav
- Shaun Thompson
- Sheryl Ann Abdukahil
- Shiranee Sriskandan
- Shirley Sarfo-Mensah
- Shona C Moore
- Silvia Bertagnolio
- Silvia Castañeda
- Simon Forsyth
- Simone Piva
- Soe Soe Thwin
- Sophia Ankrah
- Sophie Halpin
- Soulichanya Phoutthavong
- Sree Satyapriya
- Srinivas Murthy
- Srinivas Murthy
- Stephanie Roberts
- Stephanie Yerkovich
- Stephanie-Susanne Stecher
- Stephen R Knight
- Steve Webb
- Sue Smith
- Summer Hamza
- Surya Otto Wijaya
- Susanne Dudman
- Synne Jenum
- Sérgio Gaião
- Sílvia Ferreira
- Teresa Lawrence
- Thalha Rashan
- Thipsavanh Bounphiengsy
- Thushan de Silva
- Timothy M Uyeki
- Tirupakuzhi Vijayaraghavan
- Tiziana Meschi
- Tom Drake
- Tom Fletcher
- Tom Solomon
- Touxiong Yiaye
- Trude Steinsvik
- Uluhan Sili
- Valeria Balan
- Valeria Balan
- Valla Sahraei
- Vanessa Sancho-Shimizu
- Vegard Skogen
- Victoria Shaw
- Viladeth Praphasiri
- Vilmaris Quinones-Cardona
- Volkan Korten
- Waasila Jassat
- Waasila Jassat
- Wei Shen Lim
- Wendy S Barclay
- William A Paxton
- William Dechert
- William Greenhalf
- Wilna Oosthuyzen
- Xin Ci Wong
- Xin Ci Wong
- Yael Dishon
- Yaseen Arabi
- Yaseen Arabi
- Yock Ping Chow
- Yock Ping Chow
- Yvelynne Kelly
- Zulfiqar Sandhu
- Publication venue
- 'eLife Sciences Publications, Ltd'
- Publication date
- 01/01/2022
- Field of study
Background: Whilst timely clinical characterisation of infections caused by novel SARS-CoV-2 variants is necessary for evidence-based policy response, individual-level data on infecting variants are typically only available for a minority of patients and settings.
Methods: Here, we propose an innovative approach to study changes in COVID-19 hospital presentation and outcomes after the Omicron variant emergence using publicly available population-level data on variant relative frequency to infer SARS-CoV-2 variants likely responsible for clinical cases. We apply this method to data collected by a large international clinical consortium before and after the emergence of the Omicron variant in different countries.
Results: Our analysis, that includes more than 100,000 patients from 28 countries, suggests that in many settings patients hospitalised with Omicron variant infection less often presented with commonly reported symptoms compared to patients infected with pre-Omicron variants. Patients with COVID-19 admitted to hospital after Omicron variant emergence had lower mortality compared to patients admitted during the period when Omicron variant was responsible for only a minority of infections (odds ratio in a mixed-effects logistic regression adjusted for likely confounders, 0.67 [95% confidence interval 0.61-0.75]). Qualitatively similar findings were observed in sensitivity analyses with different assumptions on population-level Omicron variant relative frequencies, and in analyses using available individual-level data on infecting variant for a subset of the study population.
Conclusions: Although clinical studies with matching viral genomic information should remain a priority, our approach combining publicly available data on variant frequency and a multi-country clinical characterisation dataset with more than 100,000 records allowed analysis of data from a wide range of settings and novel insights on real-world heterogeneity of COVID-19 presentation and clinical outcome
A multi-country analysis of COVID-19 hospitalizations by vaccination status
- Author
- Aasmine Kaur
- Abby Hurd
- Abdulrahman Al-Fares
- Aditya John Anchan
- Adrian Streinu-Cercel
- Adrienne Chan
- Agostinho Monteiro
- Aidan Burrell
- Aisling Gavin
- Alan Hartman
- Aldo Rafael
- Alejandro Martín-Quiros
- Aleksander Rygh Holten
- Alessandra Notari
- Alexander J Mentzer
- Alexandros Cavayas
- Alexis F Turgeon
- Ali Ait Hssain
- Alina Kalicinska
- Alison M Meynert
- Alistair D Nichol
- Allison McGeer
- Amanda Corley
- Amna Faheem
- Ana da Silva Filipe
- Ana Freitas Ribeiro
- Ana Martins
- Anca Streinu-Cercel
- Anders Benjamin Kildal
- Anders Tveita
- Andra-Maris Post
- Andrea Angheben
- Andrea Cortegiani
- Andrea Kelly
- Andrea Rossanese
- Andrea Villoldo
- Andreas Lind
- Andrew Dagens
- Andrew Law
- Andrew Letizia
- Andy Law
- Angela Alberti
- Anika Atique
- Anjellica Chen
- Anna Beltrame
- Anne Margarita Dyrhol-Riise
- Anne McCarthy
- Anne-Marie Guerguerian
- Annemarie B Docherty
- Antonia Ho
- Antonia Ricchiuto
- Antonio Arcadipane
- António Mesquita
- Anuraj Shankar
- Argin G
- Asfia Sultana
- Asgar Rishu
- Atie Suwarti
- Audrey Dubot-Pérès
- Ayodhia Pitaloka
- Bailey Williams
- Bambang Pujo Semedi
- Baruch Joaquín
- Beathe Kiland Granerud
- Beatrice Alex
- Ben Morton
- Benjamin Bach
- Bernardo Ferreira
- Bernhard Roessler
- Bianca Boxma-de Klerk
- Birgitte Stiksrud
- Bisoffi Zeno
- Bounthavy Chaleunphon
- Bountoy Sibounheuang
- Brenda Reeve
- Brigid Flynn
- Cameron J Fairfield
- Caren Friedrich
- Carlos Cañada Illana
- Carlos Pimentel
- Caroline Kosgei
- Caroline Martins Rego
- Caroline Mudara
- Carrol Gamble
- Cassidy Codan
- Catarina Espírito Santo
- Catarina Pires
- Catherine A Shaw
- Catherine Blier
- Catherine Marquis
- Cecilia Canepa
- Ceila Maria Sant Ana Malaque
- Charlotte Summers
- Chiara Simona Cardellino
- Chiara Vitiello
- Chika Akwani
- Chloe Donohue
- Chris Kandel
- Chris McKay
- Christina Matthew
- Christl A Donnelly
- Christophe Fraser
- Christopher A Green
- Citarella Barbara Wanjiru
- Clare Jackson
- Clark D Russell
- Claudia Bianco
- Claudia Figueiredo-Mello
- Claudina Cruz
- Colin McArthur
- Cristina De Rose
- César Vieira
- Dag Henrik Reikvam
- Dan Meyer
- Dana Mustafa
- Daniel Haber
- Daniela Guerreiro
- Danilo Buonsenso
- Danoy Chommanam
- Dario Sinatti
- Dasgupta Abhishek
- Dave Nagpal
- David Bellemare
- David L Robertson
- David Maslove
- David S Y Ong
- David Stuart
- Dawn Higgins
- Debby Bogaert
- Decy Subekti
- Deepali Kumar
- Demetrios Kutsogiannis
- Denise Jaworsky
- Diana Póvoas
- Diego Franch-Llasat
- Diogo Borges
- Diogo Lopes
- Dounia Bouhmani
- Dr Rajesh Mohan Shetty
- Dwi Utomo Nusantara
- Eder Caceres
- Efstathia Mihelis
- Egle Saviciute
- Eka Airlangga
- Elisabetta Spinuzza
- Elizabeth A Ashley
- Ellen Shadowitz
- Else Quist-Paulsen
- Eman Al Qasim
- Emely Sanchez
- Emily Neumann
- Emma C Thomson
- Emmanuelle A Dankwa
- Emmanuelle Denis
- Esteban Garcia-Gallo
- Evert-Jan Wils
- Felwa Bin Humaid
- Ferran Roche-Campo
- Filipa Brás Monteiro
- Filipa Cardoso
- Filipe Cardoso
- Fiona Griffiths
- Frank Manetta
- Frank Olav Pettersen
- François Lamontagne
- François Martin Carrier
- Fredrik Müller
- Frédérick D'Aragon
- Gabriele Sales
- Gail Carson
- Gary Leeming
- Gary Schwartz
- Gayle Carney
- Gennaro Martucci
- Georgios Pollakis
- Geraldine Goco
- Gianluigi Li Bassi
- Giorgia Montrucchio
- Giovanna Occhipinti
- Giovanna Panarello
- Giulia Bertoli
- Giuseppe Foti
- Gloria Crowl
- Gonçalves Bronner P
- Graham S Cooke
- Gregory Purcell
- Gry Kloumann Bekken
- Gyan Sandhu
- Hamza Jaber
- Hannah Habraken
- Harrison Ewen M
- Hashmi Madiha
- Hayley Hardwick
- Heidi Dalton
- Heidi Gruner
- Hongru Ren
- Horby Peter
- Hubert Tessier-Grenier
- Hugo Inácio
- Husna Begum
- Iam Claire E Sarmiento
- Imrana Khalid
- Indrek Rätsep
- Ingrid G Bustos
- Isabela Saba
- ISARIC Clinical Characterisation Group: Sheryl Ann Abdukahil
- J Kevin Baird
- Jacky Y Suen
- Jake Dunning
- James Joshua Douglas
- James Lee
- James Scott-Brown
- Jan Cato Holter
- Janet Harrison
- Janet Liang
- Janet T Scott
- Janice Caoili
- Jaques Sztajnbok
- Jassat Waasila
- Jeff Powis
- Jeffrey Aliudin
- Jennifer Lee
- Jess Gibson
- Jessica Wittman
- Jia Wei
- Jimmy Ming-Yang Hsu
- Jo Dalton
- Joan Gómez-Junyent
- Joana Alves Cabrita
- Joana Cabrita
- Joana Ferrão
- John F Fraser
- John Kenneth Baillie
- John Marshall
- Jonathan Bitton
- Jorge Dantas
- Jorge Fernandes
- Jorge Paulos
- Joshua Solomon
- Josie Campisi
- José Casimiro
- José Ernesto Vidal
- José Ramalho
- Joy Ann Villanueva
- João Estevão
- João Teixeira
- Juan Pablo Horcajada
- Judit Villar
- Julia Garcia-Diaz
- Juliana Damas
- Justin Schaffer
- K Dhangar
- Kalynn Kennon
- Kamal Abu Jabal
- Karl Erik Müller
- Kartsonaki Christiana
- Katie O'Hearn
- Kenneth A McLean
- Kevin Katz
- Kraemer Moritz U G
- Kristian Tonby
- Kusum Menon
- Lana Almasri
- Lance C W Turtle
- Larissa Oliveira
- Lars Heggelund
- Latsaniphone Bountthasavong
- Laura Marsh
- Laveena Munshi
- Lefèvre Benjamin
- Leonardo Salazar
- Lina Morales Cely
- Linda Gail Skeie
- Lisa Norman
- Lisa Patterson
- Liv Hesstvedt
- Louise Sigfrid
- Luca Brazzi
- Lucia Moro
- Lucian Durham 3rd
- Luisa Quesada
- Lukas Arenz
- Lunn Miles
- Luís Val-Flores
- López Revilla José W
- Mahdad Noursadeghi
- Mahendra Singh
- Malcolm G Semple
- Mangala Narasimhan
- Manivanh Vongsouvath
- Maram Zahran
- Marc Csete
- Marco Giani
- Mare Pejkovska
- Margarite Grable
- Maria Amaral
- Maria Angelica Rivera Nuñez
- Maria de Piero
- Maria Zambon
- Mariachiara Ippolito
- Mariana Cascão
- Mariano Esperatti
- Marie Connor
- Marina Lanza
- Marina Wainstein
- Mark Downing
- Mark G Pritchard
- Marlene Santos
- Marta Alessi
- Marta Torre
- Martin-Loeches Ignacio
- Martina Escher
- Martina Hennessy
- Mary Copland
- Marília Andreia Fernandes
- Massimo Palmarini
- Mathew Thorpe
- Mathilde Duplaix
- Matteo Rossetti
- Matthew Hall
- Matthew Nelder
- Matthew Pellan Cheng
- Mayfong Mayxay
- Meera Chand
- Merson Laura
- Mical Paul
- Michael Edelstein
- Michael Schwameis
- Michael Varrone
- Michaela Barnikel
- Michele Petrovic
- Michelle E Kho
- Michelle Girvan
- Mo'nes Muhaisen
- Moad Atlowly
- Mohammed Alkahlout
- Moji Ghadimi
- Muge Cevik
- Murray Dryden
- Murray Wham
- Musharaf Sadat
- Mutia Rahardjani
- Mário Ferraz
- Nashat Abu Salah
- Nataly Farshait
- Nathaniel Christy
- Netta Beer
- Nicholas Yuri Barbosa
- Nick Daneman
- Nicole White
- Nidyanara Castanheira
- Nimisha Abdul Majeed
- Nina Buchtele
- Nora Fuentes
- Nuno Germano
- Oana Sandulescu
- Oleksa Rewa
- Olliaro Piero L
- Ooyanong Phonemixay
- Osama Aldabbourosama
- Paola Rodari
- Paolo Cattaneo
- Patricia Fontela
- Patricia Patricio
- Patrick Archambault
- Paul Klenerman
- Paula Custodio
- Pauline Yeung Ng
- Pawel Twardowski
- Pedro Faria
- Peter Daley
- Peter Kiiza
- Peter Openshaw
- Philippe Jouvet
- Phoebe Ampaw
- Phouvieng Douangdala
- Piero Valentini
- Piret Sillaots
- Piubelli Chiara
- Prasan Kumar Panda
- Prashant Nasa
- Praveen Kumar Ghisulal
- Rachael McConnochie
- Rachael Parke
- Rajavardhan Rangappa
- Rakesh Arora
- Raph L Hamers
- Renata Barbalho
- Reyes Luis Felipe
- Richard S Tedder
- Riinu Pius
- Rima Song
- Rita Alves
- Robert A Fowler
- Roberta Cavalin
- Rojek Amanda
- Rolando Claure-Del Granado
- Roman Ullrich
- Rosario Maria Torres Santos-Olmo
- Ross Hendry
- Rui Caetano Garcês
- Rui Garcês
- Rui Pereira
- Rupert Higgins
- Ruth Lyons
- Ryan S Thwaites
- Sadie Kelly
- Samantha Lissauer
- Samreen Ijaz
- Samuel Hinton
- Sanne Wesselius
- Sara Clohisey
- Sara Machado
- Sara Taleb
- Sarah E McDonald
- Sarah Moore
- Saye Khoo
- Scott Pharand
- Sergio Poli
- Seán Keating
- Shaher Hamdan
- Shaun Thompson
- Shiranee Sriskandan
- Shirin Tabrizi
- Shirley Sarfo-Mensah
- Shona C Moore
- Shrapnel Sally
- Silvia Castañeda
- Simon Forsyth
- Sofia Cardoso
- Sommay Keomany
- Sophie Halpin
- Soulichanya Phoutthavong
- Srinivas Murthy
- Stephanie Roberts
- Stephanie Yerkovich
- Stephanie-Susanne Stecher
- Stephen R Knight
- Steve Webb
- Sue Smith
- Sue Willems
- Summer Hamza
- Susanne Dudman
- Synne Jenum
- Teresa Lawrence
- Thipsavanh Bounphiengsy
- Thomas Drake
- Thomas Staudinger
- Thushan de Silva
- Tiago Isidoro
- Timothy M Uyeki
- Todd C Lee
- Tom Fletcher
- Tom Solomon
- Touxiong Yiaye
- Triona Downer
- Trude Steinsvik
- Tânia Sequeira
- Valeria Balan
- Valla Sahraei
- Vanessa Sancho-Shimizu
- Vegard Skogen
- Victoria Shaw
- Viladeth Praphasiri
- Virginie Williams
- Volkan Korten
- Wael Hafez
- Wai Ching Sin
- Wei Shen Lim
- Wendy S Barclay
- William A Paxton
- William Dechert
- William Greenhalf
- Wilna Oosthuyzen
- Yael Dishon
- Yaseen Arabi
- Yock Ping Chow
- Yousef Al-Saba'a
- Yusing Gu
- Zaina Dalloul
- Publication venue
- Publication date
- 12/09/2023
- Field of study
Background: Individuals vaccinated against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), when infected, can still develop disease that requires hospitalization. It remains unclear whether these patients differ from hospitalized unvaccinated patients with regard to presentation, coexisting comorbidities, and outcomes. Methods: Here, we use data from an international consortium to study this question and assess whether differences between these groups are context specific. Data from 83,163 hospitalized COVID-19 patients (34,843 vaccinated, 48,320 unvaccinated) from 38 countries were analyzed. Findings: While typical symptoms were more often reported in unvaccinated patients, comorbidities, including some associated with worse prognosis in previous studies, were more common in vaccinated patients. Considerable between-country variation in both in-hospital fatality risk and vaccinated-versus-unvaccinated difference in this outcome was observed. Conclusions: These findings will inform allocation of healthcare resources in future surges as well as design of longer-term international studies to characterize changes in clinical profile of hospitalized COVID-19 patients related to vaccination history. Funding: This work was made possible by the UK Foreign, Commonwealth and Development Office and Wellcome (215091/Z/18/Z, 222410/Z/21/Z, 225288/Z/22/Z, and 220757/Z/20/Z); the Bill & Melinda Gates Foundation (OPP1209135); and the philanthropic support of the donors to the University of Oxford's COVID-19 Research Response Fund (0009109). Additional funders are listed in the "acknowledgments" section
Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective, multinational, observational study
- Author
- Abbas Ali
- Abdukahil Sheryl Ann
- Abe Ryuzo
- Abel Laurent
- Abreu Julia Rodriguez
- Absil Lara
- Acharya Subhash
- Acker Andrew
- Adrião Diana
- Ahmed Shakeel
- Ainscough Kate
- Aisa Tharwat
- Akimoto Takako
- Akmal Ernita
- Al Ageel Saleh
- Al Qasim Eman
- Al-dabbous Tala
- Al-Fares Abdulrahman
- Alalqam Razi
- Alegesan Senthilkumar
- Alegre Cynthia
- Alessi Marta
- Alex Beatrice
- Alexandre K. vin
- Alfoudri Huda
- Ali Imran
- Alidjnou Kazali Enagnon
- Aliudin Jeffrey
- Alkhafajee Qabas
- Allavena Clotilde
- Allou Nathalie
- Altaf Aneela
- Alves João
- Alves João Melo
- Alves Rita
- Amaral Maria
- Ampaw Phoebe
- Andini Roberto
- Andréjak Claire
- Angheben Andrea
- Angoulvant François
- Ansart S. verine
- Antonelli Massimo
- Apriyana Ardiyan
- Arabi Yaseen
- Aragao Irene
- Araujo Carolline
- Arcadipane Antonio
- Archambault Patrick
- Arenz Lukas
- Argin G.
- Arlet Jean-Benoît
- Arnold-Day Christel
- Arora Lovkesh
- Arora Rakesh
- Artaud-Macari Elise
- Aryal Diptesh
- Asensio Angel
- Asif Namra
- Asim Mohammad
- Assie Jean Baptiste
- Atif Minahel
- Atique Anika
- Attanyake A. M. Udara Lakshan
- Auchabie Johann
- Auger Christelle Chantalat
- Aumaitre Hugues
- Auvet Adrien
- Azemar Laurène
- Azoulay Cecile
- Bach Benjamin
- Bachelet Delphine
- Badr Claudine
- Baig Nadia
- Baillie J. Kenneth
- Bak Erica
- Bakakos Agamemnon
- Bal Andriy
- Balan Valeria
- Balazote Pablo Serrano
- Banheiro Bruno Sarmento
- Bani-Sadr Firouzé
- Barbalho Renata
- Barclay Wendy S.
- Barnikel Michaela
- Barrasa Helena
- Barrelet Audrey
- Barrigoto Cleide
- Barrio Noelia García
- Bartoli Marie
- Baruch Joaquín
- Basmaci Romain
- Bassi Gianluigi Li
- Battaglini Denise
- Bauer Jules
- Beane Abigail
- Bedossa Alexandra
- Begum Husna
- Behilill Sylvie
- Beishuizen Albertus
- Bekken Gry Kloumann
- Beljantsev Aleksandr
- Bellemare David
- Beltrame Anna
- Beluze Marine
- Benech Nicolas
- Benkerrou Dehbia
- Bennett Suzanne
- Bento Luís
- Berdal Jan-Erik
- Bergeaud Delphine
- Bergin Hazel
- Bermejo Carlos Lumbreras
- Bermúdez Juan Luis Cruz
- Bertoli Giulia
- Bertolino Lorenzo
- Bessis Simon
- Bevilcaqua Sybille
- Bezulier Karine
- Bhatt Amar
- Bhavsar Krishna
- Bianco Claudia
- Bissuel François
- Bitker Laurent
- Bitton Jonathan
- Blanco-Schweizer Pablo
- Blier Catherine
- Bloos Frank
- Blot Mathieu
- Boccia Filomena
- Bodenes Laetitia
- Bogaert Debby
- Boivin Anne-H. lène
- Bolze Pierre-Adrien
- Bompart François
- Borges Diogo
- Borie Raphaël
- Bosse Hans Martin
- Botelho-Nevers Elisabeth
- Bouadma Lila
- Bouchaud Olivier
- Bouchez Sabelline
- Bouhmani Dounia
- Bouhour Damien
- Bouiller K. vin
- Bouillet Laurence
- Bouisse Camile
- Boureau Anne-Sophie
- Bourke John
- Bouscambert Maude
- Bousquet Aurore
- Bouziotis Jason
- Boxma Bianca
- Boyer-Besseyre Marielle
- Boylan Maria
- Bozza Fernando
- Braconnier Axelle
- Braga Cynthia
- Brandenburger Timo
- Brazzi Luca
- Breen Dorothy
- Breen Patrick
- Brickell Kathy
- Brien Fionnuala O.
- Browne Alex
- Browne Shaunagh
- Brusse-Keizer Marjolein
- Buchtele Nina
- Buesaquillo Christian
- Bugaeva Polina
- Buisson Marielle
- Burhan Erlina
- Burrell Aidan
- Bustos Ingrid G.
- Butnaru Denis
- Cabie André
- Cabral Susana
- Cabrita Joana Alves
- Caceres Eder
- Cadoz Cyril
- Callaghan Annmarie O.
- Calligy Kate
- Calvache Jose Andres
- Campana Valentine
- Campbell Paul
- Camões João
- Canepa Cecilia
- Cantero Mireia
- Caraux-Paz Pauline
- Cardellino Chiara Simona
- Cardoso Filipa
- Cardoso Filipe
- Cardoso Nelson
- Cardoso Sofia
- Carelli Simone
- Carlier Nicolas
- Carmoi Thierry
- Carney Gayle
- Carqueja Inês
- Carret Marie-Christine
- Carrier François Martin
- Carroll Ida
- Carson Gail
- Casanova Maire-Laure
- Cascão Mariana
- Casey Siobhan
- Casimiro José
- Cassandra Bailey
- Castanheira Nidyanara
- Castañeda Silvia
- Castor-Alexandre Guylaine
- Castrillón Henry
- Castro Ivo
- Catarino Ana
- Catherine François-Xavier
- Cattaneo Paolo
- Cavalin Roberta
- Cavalli Giulio Giovanni
- Cavayas Alexandros
- Ceccato Adrian
- Cely Lina Morales
- Cervantes-Gonzalez Minerva
- Chair Anissa
- Chakveatze Catherine
- Chan Adrienne
- Chand Meera
- Chapplain Jean-Marc
- Chas Julie
- Chaudry Mobin
- Chen Anjellica
- Chen Yih-Sharng
- Cheng Matthew Pellan
- Cheret Antoine
- Chia Jack Song
- Chiarabini Thibault
- Chica Julian
- Chirouze Catherine
- Chiumello Davide
- Cho Sung-Min
- Choileain Orna Ni
- Cholley Bernard
- Chopin Marie-Charlotte
- Cidade Jose Pedro
- Citarella Barbara Wanjiru
- Ciullo Anna
- Clarke Emma
- Clarke Jennifer
- Clohisey Sara
- Cobb Perren J.
- Codan Cassidy
- Cody Caitriona
- Coelho Alexandra
- Coles Megan
- Colin Gwenhaël
- Collins Michael
- Colombo Sebastiano Maria
- Combs Pamela
- Connor Marie
- Conrad Anne
- Contreras Sofía
- Conway Elaine
- Cooke Graham S.
- Copland Mary
- Cordel Hugues
- Corley Amanda
- Cornelis Sabine
- Cornet Alexander Daniel
- Corpuz Arianne Joy
- Cortegiani Andrea
- Corvaisier Grégory
- Costigan Emma
- Couffignal Camille
- Couffin-Cadiergues Sandrine
- Courtois Roxane
- Cousse Stéphanie
- Cregan Rachel
- Croonen Sabine
- Crowl Gloria
- Crump Jonathan
- Cruz Claudina
- Csete Marc
- Cullen Ailbhe
- Cummings Matthew J.
- Curley Ger
- Curlier Elodie
- Curran Colleen
- Custodio Paula
- Cárcel Sheila
- da Silva Filipe Ana
- da Silveira Charlene
- Dabaliz Al-Awwab
- Dagens Andrew
- Dahly Darren
- Dalton Heidi
- Dalton Jo
- Daly Seamus
- Damas Juliana
- Daneman Nick
- Daniel Corinne
- Dankwa Emmanuelle A.
- Dantas Jorge
- Darshana B. P. Sanka Ruwan Sri
- de Brito Carlos Alexandre Antunes
- de Castro Maisa Guimarães
- de la Calle Guillermo Maestro
- de Loughry Gillian
- de Mendoza Diego
- de Montmollin Etienne
- de Oliveira França Rafael Freitas
- de Pinho Oliveira Ana Isabel
- de Rosa Rosanna
- de Silva Thushan
- de Vries Peter
- Deacon Jillian
- Dean David
- Debard Alexa
- Debray Marie-Pierre
- DeCastro Nathalie
- Dechert William
- Deconninck Lauren
- Decours Romain
- Defous Eve
- Delacroix Isabelle
- Delaveuve Eric
- Delavigne Karen
- Dell’Amore Andrea
- Delmas Christelle
- Delobel Pierre
- Delsing Corine
- Demonchy Elisa
- Denis Emmanuelle
- Deplanque Dominique
- Depuydt Pieter
- Descamps Diane
- Desvallées Mathilde
- Devouge Eglantine Ferrand
- Dewayanti Santi
- Dhanger Pathik
- Diallo Alpha
- Diamantis Sylvain
- Dias André
- Diaz Juan Jose
- Diaz Priscila
- Diaz Rodrigo
- Didier K. vin
- Diehl Jean-Luc
- Dieperink Wim
- Dimet J. rôme
- Dinot Vincent
- Diop Fara
- Diouf Alphonsine
- Dishon Yael
- Djossou F. lix
- Docherty Annemarie B.
- Doherty Helen
- Dominguez Carmen Infante
- Dondorp Arjen M.
- Donnelly Christl A.
- Donnelly Maria
- Donohue Chloe
- Donohue Sean
- Donohue Yoann
- Doran Peter
- Dorival C. line
- Douglas James Joshua
- Dournon Nathalie
- Dow Denisse Bazan
- Downer Triona
- Downey Joanne
- Downing Mark
- Drake Tom
- Driscoll Aoife
- Dubee Vincent
- Dubos François
- Ducancelle Alexandre
- Dudman Susanne
- Dunand Paul
- Dunning Jake
- Duplaix Mathilde
- Duque Sara
- Durante-Mangoni Emanuele
- Durham Lucian
- Dussol Bertrand
- Duthoit Juliette
- Duval Xavier
- Dyrhol-Riise Anne Margarita
- D’Aragon Frédérick
- D’Ortenzio Eric
- Echeverria-Villalobos Marco
- Egan Siobhan
- Eira Carla
- Elapavaluru Subbarao
- Elharrar Brigitte
- Ellerbroek Jacobien
- Eloy Philippine
- Elshazly Tarek
- Enderle Isabelle
- Endo Tomoyuki
- Engelmann Ilka
- Enouf Vincent
- Epaulard Olivier
- Escher Martina
- Esperatti Mariano
- Esperou H. lène
- Esposito-Farese Marina
- Estevão João
- Etienne Manuel
- Ettalhaoui Nadia
- Everding Anna Greti
- Evers Mirjam
- Fabre Isabelle
- Fabre Marc
- Faheem Amna
- Fahy Arabella
- Fairfield Cameron J.
- Fakar Zul
- Fareed Komal
- Faria Pedro
- Farooq Ahmed
- Fatoni Arie Zainul
- Faure Karine
- Favory Raphaël
- Fayed Mohamed
- Feely Niamh
- Feeney Laura
- Fernandes Jorge
- Fernandes Marília Andreia
- Fernandes Susana
- Ferrand François-Xavier
- Ferraz M. rio
- Ferreira Benigno
- Ferreira Bernardo
- Ferreira Isabel
- Ferreira S. lvia
- Ferrer-Roca Ricard
- Ferriere Nicolas
- Ferrão Joana
- Ficko C. line
- Figueiredo-Mello Claudia
- Fiorda Juan
- Flament Thomas
- Flateau Clara
- Fletcher Tom
- Florio Letizia Lucia
- Flynn Deirdre
- Foley Claire
- Foley Jean
- Fomin Victor
- Fonseca Claudio Duarte
- Fonseca Tatiana
- Fontela Patricia
- Forsyth Simon
- Foster Denise
- Foti Giuseppe
- Fourn Erwan
- Fowler Robert A.
- Fraher Marianne
- Franch-Llasat Diego
- Fraser Christophe
- Fraser John F.
- Freire Marcela Vieira
- French Craig
- Friedrich Caren
- Fry Stéphanie
- Fuentes Nora
- Fuentes Yuli V.
- Fukuda Masahiro
- Gaborieau Valérie
- Gaci Rostane
- Gagliardi Massimo
- Gagnard Jean-Charles
- Gagneux-Brunon Amandine
- Gaião S. rgio
- Gallagher Phil
- Gamble Carrol
- Gandonniere Charlotte Salmon
- Garan Arthur
- Garcia Rebekha
- Garcia-Gallo Esteban
- Garcês Rui Caetano
- García Ruth N. Jorge
- Garimella Navya
- Garot Denis
- Garrait Valérie
- Gauli Basanta
- Gault Nathalie
- Gavin Aisling
- Gavrylov Anatoliy
- Gaymard Alexandre
- Gebauer Johannes
- Geraud Eva
- Germano Nuno
- Ghosn Jade
- Giani Marco
- Gibson Jess
- Gigante Tristan
- Gilg Morgane
- Gilroy Elaine
- Giordano Guillermo
- Girvan Michelle
- Gissot Valérie
- Glikman Daniel
- Glybochko Petr
- Gnall Eric
- Goco Geraldine
- Goehringer François
- Goepel Siri
- Goffard Jean-Christophe
- Golob Jonathan
- Gominet Marie
- Gonzalez Alicia
- González V. ctor Quirós
- Gonçalves Bronner P.
- Gordon Patricia
- Gorenne Isabelle
- Goubert Laure
- Goujard C. cile
- Goulenok Tiphaine
- Grable Margarite
- Graf Jeronimo
- Grandin Edward Wilson
- Granerud Beathe Kiland
- Granier Pascal
- Grasselli Giacomo
- Green Christopher A.
- Greene Courtney
- Greenhalf William
- Greffe Segolène
- Grieco Domenico Luca
- Griffee Matthew
- Griffiths Fiona
- Groenendijk Albert
- Gruner Heidi
- Gu Yusing
- Guedj J. rémie
- Guego Martin
- Guellec Dewi
- Guerguerian Anne-Marie
- Guerreiro Daniela
- Guery Romain
- Guillaumot Anne
- Guilleminault Laurent
- Guimard Thomas
- Gómez-Junyent Joan
- Haalboom Marieke
- Haber Daniel
- Habraken Hannah
- Hachemi Ali
- Hadri Nadir
- Haidri Fakhir
- Hakak Sheeba
- Hall Adam
- Hall Matthew
- Halpin Sophie
- Hameed Jawad
- Hamer Ansley
- Hamidfar Rebecca
- Hammond Terese
- Haniffa Rashan
- Hardwick Hayley
- Harrison Ewen M.
- Harrison Janet
- Harrison Samuel Bernard Ekow
- Hasan Mohd Shahnaz
- Hashmi Junaid
- Hashmi Madiha
- Hayat Muhammad
- Hayes Ailbhe
- Hays Leanne
- Heerman Jan
- Heggelund Lars
- Hendry Ross
- Hennessy Martina
- Hentzien Maxime
- Herreros José Miguel Cisneros
- Hershey Andrew
- Hesstvedt Liv
- Hidayah Astarini
- Higgins Dawn
- Higgins Eibhilin
- Higgins Rupert
- Hinchion Rita
- Hinton Samuel
- Hitoto Hikombo
- Ho Antonia
- Hoctin Alexandre
- Hoffmann Isabelle
- Hoiting Oscar
- Holt Rebecca
- Holten Aleksander Rygh
- Holter Jan Cato
- Horby Peter
- Horcajada Juan Pablo
- Hoshino Koji
- Hoshino Kota
- Houas Ikram
- Hough Catherine L.
- Hssain Ali Ait
- Hsu Jimmy Ming-Yang
- Hulot Jean-S. bastien
- Humaid Felwa Bin
- Huo Stella
- Hurd Abby
- Hussain Iqbal
- Ibáñez-Prada Elsa D.
- Ijaz Samreen
- Ikram Arfan
- Illes Hajnal-Gabriela
- Imbert Patrick
- Imran Mohammad
- Imtiaz Aftab
- Inácio Hugo
- Ippolito Mariachiara
- Isgett Sarah
- Isidoro Tiago
- Isnard Margaux
- Ivulich Daniel
- Iñiguez Jonathan Samuel Chávez
- Jaafar Danielle
- Jaafoura Salma
- Jabot Julien
- Jackson Clare
- Jamieson Nina
- Jaquet Pierre
- Jaud-Fischer Coline
- Jaureguiberry Stéphane
- Jego Florence
- Jenum Synne
- Jiménez Miguel Pedrera
- Joseph C. dric
- Joseph Mark
- Joshi Swosti
- Jourdain Mercé
- Jouvet Philippe
- Jung Anna
- Juzar Dafsah
- Kafif Ouifiya
- Kaguelidou Florentia
- Kali Sabina
- Kalomoiri Smaragdi
- Kandamby Darshana Hewa
- Kandel Chris
- Kanwal Darakhshan
- Kartsonaki Christiana
- Kataria Anant
- Katz Kevin
- Kay Christy
- Keane Hannah
- Keating Seán
- Kelly Andrea
- Kelly Aoife
- Kelly Claire
- Kelly Niamh
- Kelly Sadie
- Kelly Yvelynne
- Kelsey Maeve
- Kennon Kalynn
- Kernan Maeve
- Kerroumi Younes
- Keshav Sharma
- Khalid Imrana
- Khalid Osama
- Khalil Antoine
- Khan Coralie
- Khan Irfan
- Khan Quratul Ain
- Khan Rashid Nasim
- Khanal Sushil
- Khatak Abid
- Khawaja Amin
- Kho Michelle E.
- Khoo Saye
- Khoso Nasir
- Kida Yuri
- Kiiza Peter
- Kildal Anders Benjamin
- Kimmoun Antoine
- Kindgen-Milles Detlef
- Kitamura Nobuya
- Klenerman Paul
- Klont Rob
- Knight Stephen R.
- Kobbe Robin
- Kodippily Chamira
- Koirala Sabin
- Kosgei Caroline
- Kpangon Arsène
- Krawczyk Karolina
- Kruglova Oksana
- Kumar Deepali
- Kumar Mukesh
- Kuriakose Dinesh
- Kurtzman Ethan
- Kutsogiannis Demetrios
- Kutsyna Galyna
- Kyriakoulis Konstantinos
- Lachatre Marie
- Lacoste Marie
- Laffey John G.
- Lagrange Marie
- Laine Fabrice
- Lairez Olivier
- Lakhey Sanjay
- Lalueza Antonio
- Lambert Marc
- Lamontagne François
- Langelot-Richard Marie
- Langlois Vincent
- Lantang Eka Yudha
- Lanza Marina
- Laouénan C. dric
- Laribi Samira
- Lariviere Delphine
- Lasry Stéphane
- Latif Naveed
- Launay Odile
- Laureillard Didier
- Lavie-Badie Yoan
- Law Andrew
- Lawrence Cassie
- Lawrence Teresa
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- le Bris Cyril
- le Falher Georges
- le Fevre Lucie
- le Hingrat Quentin
- le Maréchal Marion
- le Mestre Soizic
- le Moal Gwenaël
- le Moing Vincent
- le Nagard Hervé
- le Turnier Paul
- le Minh
- Leal Ema
- Leathlobhair Niamh Ni
- Lee James
- Lee Jennifer
- Lee Su Hwan
- Lee Todd C.
- Leeming Gary
- Lefebvre B. nédicte
- Lefebvre Laurent
- Lefèvre Benjamin
- LeGac Sylvie
- Lelievre Jean-Daniel
- Lellouche François
- Lemaignen Adrien
- Lemee V. ronique
- Lemeur Anthony
- Lemmink Gretchen
- Lennon Jenny
- Leone Marc
- Leone Michela
- Lescure François-Xavier
- Lesens Olivier
- Lesouhaitier Mathieu
- Lester-Grant Amy
- Levy Bruno
- Levy Yves
- Levy-Marchal Claire
- Lewandowska Katarzyna
- León Rafael
- Liaquat Ali
- Liegeon Geoffrey
- Lim Wei Shen
- Lima Chantre
- Lina Bruno
- Lind Andreas
- Lingas Guillaume
- Lion-Daolio Sylvie
- Liu Keibun
- Livrozet Marine
- Lizotte Patricia
- Loforte Antonio
- Lolong Navy
- Lopes Diogo
- Lordemann Anja Grosse
- Loschner Anthony L.
- Loubet Paul
- Loufti Bouchra
- Louis Guillame
- Lourenco Silvia
- Lovelace-Macon Lara
- Lowik Marije
- Lucet Jean Christophe
- Luna Carlos M.
- Luong Liem
- Luque Nestor
- Luton Dominique
- Lwin Nilar
- Lyons Ruth
- l’Her Erwan
- Maasikas Olavi
- Mabiala Oryane
- Machado Moïse
- Machado Sara
- Macheda Gabriel
- Madiha Hashmi
- Mahieu Rafael
- Mahy Sophie
- Maia Ana Raquel
- Maier Lars S.
- Maillet Mylène
- Maitre Thomas
- Malaque Ana
- Malfertheiner Maximilian
- Malik Nadia
- Mallon Paddy
- Maltez Fernando
- Malvy Denis
- Manda Victoria
- Mandelbrot Laurent
- Mankikian Julie
- Manning Edmund
- Manuel Aldric
- Marino Daniel
- Marino Flávio
- Markowicz Samuel
- Marques Ana
- Marquis Catherine
- Marsh Brian
- Marsh Laura
- Marshal Megan
- Marshall John C.
- Martelli Celina Turchi
- Martin Emily
- Martin-Blondel Guillaume
- Martin-Loeches Ignacio
- Martinot Martin
- Martins Ana
- Martins João
- Martins Nuno
- Martucci Gennaro
- Martynenko Olga
- Marwali Eva Miranda
- Maslove David
- Mason Sabina
- Masood Sobia
- Matan Moshe
- Mathew Meghena
- Mathieu Daniel
- Mattei Mathieu
- Matulevics Romans
- Maulin Laurence
- Maxwell Michael
- Maynar Javier
- Mazzoni Thierry
- Mc Evoy Natalie
- Mc Sweeney Lisa
- McArthur Colin
- McArthur Colin
- McCarthy Aine
- McCarthy Anne
- McCloskey Colin
- McConnochie Rachael
- McDermott Sherry
- McDonald Sarah E.
- McElroy Aine
- McElwee Samuel
- McEneany Victoria
- McGeer Allison
- McKay Chris
- McKeown Johnny
- McLean Kenneth A.
- McNally Paul
- McNicholas Bairbre
- McPartlan Elaine
- Meaney Edel
- Mear-Passard C. cile
- Mechlin Maggie
- Meher Maqsood
- Mele Ferruccio
- Melo Luis
- Memon Kashif
- Mendes Joao Joao
- Menkiti Ogechukwu
- Menon Kusum
- Mentré France
- Mentzer Alexander J.
- Mercier Emmanuelle
- Mercier Noémie
- Merckx Antoine
- Mergeay-Fabre Mayka
- Mergler Blake
- Merson Laura
- Mesquita António
- Metwally Osama
- Meybeck Agnès
- Meyer Dan
- Meynert Alison M.
- Meysonnier Vanina
- Meziane Amina
- Mezidi Mehdi
- Michelanglei C. line
- Michelet Isabelle
- Mihnovit Vladislav
- Mohammed Nassima Si
- Mohd-Hanafiah Farah Nadia
- Moin Asma
- Molina David
- Molinos Elena
- Molloy Brenda
- Mone Mary
- Monteiro Agostinho
- Monteiro Filipa Brás
- Montes Claudia
- Montrucchio Giorgia
- Moore Sarah
- Moore Shona C.
- Morlaes Louis Gerbaud
- Moro Lucia
- Motherway Catherine
- Motos Ana
- Mouquet Hugo
- Moyet Julien
- Mufti Aisha Kalsoom
- Mullaert Jimmy
- Munblit Daniel
- Muneeb Syed
- Munir Nadeem
- Murphy Aisling
- Murphy Aisling
- Murphy Lorna
- Murris Marlène
- Murthy Srinivas
- Musaab Himed
- Muvindi Himasha
- Myrodia Dimitra Melia
- Müller Fredrik
- Müller Karl Erik
- Nagpal Dave
- Nagrebetsky Alex
- Narayanan Nageswaran
- Nazerali-Maitland Alasdair
- Neant Nadège
- Nekliudov Nikita
- Neto Ary Serpa
- Neto Raul
- Neumann Emily
- Ng Pauline Yeung
- Nghi Anthony
- Nguyen Duc
- Nichol Alistair
- Nitayavardhana Prompak
- Nonas Stephanie
- Nor Basri Mat
- Nor Basri Mat
- Noret Marion
- Norman Lisa
- Notari Alessandra
- Noursadeghi Mahdad
- Nowinski Adam
- Nseir Saad
- Nunez Jose I.
- Nurnaningsih Nurnaningsih
- Nyamankolly Elsa
- Occhipinti Giovanna
- OConnor Derbrenn
- Ogston Tawnya
- Ogura Takayuki
- Oliveira João
- Oliveira Larissa
- Olliaro Piero L.
- Ong David S. Y.
- Oosthuyzen Wilna
- Opavsky Anne
- Openshaw Peter
- Orakzai Saijad
- Orozco-Chamorro Claudia Milena
- Ortoleva Jamel
- Osatnik Javier
- Ouamara Nadia
- Ouissa Rachida
- Oziol Eric
- O’Callaghan Annmarie
- O’Donnell Max
- O’Halloran Sophie
- O’Hearn Katie
- O’Shea Linda
- O’Sullivan Miriam
- Pagadoy Maïder
- Pages Justine
- Palacios Amanda
- Palacios Mario
- Palmarini Massimo
- Panarello Giovanna
- Panda Prasan Kumar
- Paneru Hem
- Panigada Mauro
- Pansu Nathalie
- Papadopoulos Aurélie
- Parke Rachael
- Parker Melissa
- Parra Briseida
- Pasha Taha
- Pasquier J. rémie
- Pastene Bruno
- Patauner Fabian
- Patricio Patricia
- Patrier Juliette
- Patrão Luís
- Patterson Lisa
- Pattnaik Rajyabardhan
- Paul Christelle
- Paul Mical
- Paulos Jorge
- Paxton William A.
- Payen Jean-François
- Peelman Florent
- Peiffer-Smadja Nathan
- Peigne Vincent
- Pejkovska Mare
- Pelosi Paolo
- Peltan Ithan D.
- Pereira Rui
- Perez Daniel
- Periel Luis
- Perpoint Thomas
- Perrot Clara Mouton
- Pesenti Antonio
- Pestre Vincent
- Petrou Lenka
- Petrov-Sanchez Ventzislava
- Petrovic Michele
- Pettersen Frank Olav
- Peytavin Gilles
- Pharand Scott
- Picard Walter
- Picone Olivier
- Pierobon Carola
- Piersma Djura
- Pimentel Carlos
- Pinto Raquel
- Pires Catarina
- Pironneau Isabelle
- Piroth Lionel
- Pius Riinu
- Plantier Laurent
- Poissy Julien
- Pokeerbux Ryadh
- Poli Sergio
- Pollakis Georgios
- Ponscarme Diane
- Post Andra-Maris
- Postma Douwe F.
- Povoa Pedro
- Powis Jeff
- Prapa Sofia
- Preau S. bastien
- Prebensen Christian
- Preiser Jean-Charles
- Prinssen Anton
- Pritchard Mark G.
- Priyadarshani Gamage Dona Dilanthi
- Proença Lucia
- Pudota Sravya
- Pulicken Mathew
- Purcell Gregory
- Puéchal Oriane
- Póvoas Diana
- Quesada Luisa
- Quinones-Cardona Vilmaris
- Quist-Paulsen Else
- Quraishi Mohammed
- Rabaud Christian
- Rabindrarajan Ebenezer
- Rafael Aldo
- Rafiq Marie
- Rahutullah Arsalan
- Rainieri Fernando
- Ramachandran Pratheema
- Ramakrishnan Nagarajan
- Ramalho José
- Rammaert Blandine
- Ramos Grazielle Viana
- Rana Asim
- Rangappa Rajavardhan
- Ranjan Ritika
- Rapp Christophe
- Rashan Aasiyah
- Rashan Thalha
- Rasheed Ghulam
- Rasmin Menaldi
- Rau Cornelius
- Raza Ali
- Real Andre
- Rebaudet Stanislas
- Redl Sarah
- Reeve Brenda
- Rego Caroline Martins
- Rehman Attaur
- Reid Liadain
- Reid Liadain
- Reikvam Dag Henrik
- Reis Renato
- Rello Jordi
- Remppis Jonathan
- Remy Martine
- Ren Hongru
- Renk Hanna
- Resseguier Anne-Sophie
- Revest Matthieu
- Rewa Oleksa
- Reyes Luis Felipe
- Reyes Tiago
- Ribeiro Ana Freitas
- Ribeiro Maria Ines
- Richardson David
- Richardson Denise
- Richier Laurent
- Riera Jordi
- Rincon Diego Fernando Bautista
- Rios Ana L.
- Rishu Asgar
- Rispal Patrick
- Risso Karine
- Rizer Nicholas
- Robba Chiara
- Roberto André
- Roberts Stephanie
- Robertson David L.
- Robineau Olivier
- Roche-Campo Ferran
- Rodari Paola
- Rodeia Simão
- Roessler Bernhard
- Roger Pierre-Marie
- Rojek Amanda
- Rojo Jaime Cruz
- Romaru Juliette
- Roncon-Albuquerque Roberto
- Roriz M. lanie
- Rosa-Calatrava Manuel
- Rose Michael
- Rosenberger Dorothea
- Rossanese Andrea
- Rossetti Matteo
- Rossignol B. nédicte
- Rossignol Patrick
- Rousset Stella
- Roy Carine
- Roze Benoît
- Rusmawatiningtyas Desy
- Russell Clark D.
- Ryan Maeve
- Ryan Maria
- Ryckaert Steffi
- Rätsep Indrek
- Saba Isabela
- Sadaf Sairah
- Sadat Musharaf
- Sahraei Valla
- Saidani Nadia
- Saint-Gilles Maximilien
- Sakiyalak Pranya
- Salahuddin Nawal
- Salazar Leonardo
- Saleem Jodat
- Sales Gabriele
- Sallaberry Stéphane
- Salvator H. lène
- Sanchez Olivier
- Sanchez-Miralles Angel
- Sancho-Shimizu Vanessa
- Sandhu Gyan
- Sandhu Zulfiqar
- Sandrine Pierre-François
- Sandulescu Oana
- Sanharawi Mohammed El
- Sant Ceila Maria
- Santo Catarina Espírito
- Santos Marlene
- Santos Marta Leal
- Sarfo-Mensah Shirley
- Sarton Benjamine
- Satyapriya Sree
- Satyawati Rumaisah
- Saviciute Egle
- Schaffer Justin
- Schermer Tjard
- Scherpereel Arnaud
- Schneider Marion
- Schroll Stephan
- Schwameis Michael
- Scott Janet T.
- Scott-Brown James
- Sedillot Nicholas
- Seitz Tamara
- Selvanayagam Jaganathan
- Semaille Caroline
- Semedi Bambang Pujo
- Semple Malcolm G.
- Senneville Eric
- Sequeira Filipa
- Sequeira T. nia
- Shadowitz Ellen
- Shah Naseem Ali
- Shamsah Mohammad
- Sharjeel Shaikh
- Sharma Pratima
- Shaw Catherine A.
- Shaw Victoria
- Sheharyar Ashraf
- Shetty Rajesh Mohan
- Shi Haixia
- Shiekh Mohiuddin
- Shimizu Keiki
- Shrapnel Sally
- Shrestha Pramesh Sundar
- Shrestha Shubha Kalyan
- Shukeri Wan Fadzlina Wan Muhd
- Shum Hoi Ping
- Sibiude Jeanne
- Siddiqui Atif
- Sigfrid Louise
- Sikander Rana Imran
- Sillaots Piret
- Silva Catarina
- Silva Maria Joao
- Silva Rogério
- Sin Wai Ching
- Singh Budha Charan
- Singh Moirangthem Bikram
- Singh Punam
- Sitompul Pompini Agustina
- Skeie Linda Gail
- Skogen Vegard
- Smith Sue
- Smood Benjamin
- Smyth Coilin
- Smyth Michelle
- Smyth Michelle
- Snacken Morgane
- So Dominic
- Sobrino José Luis Bernal
- Solomon Joshua
- Solomon Tom
- Somers Emily
- Sommet Agnès
- Song Myung Jin
- Song Rima
- Song Tae
- Sotto Albert
- Soum Edouard
- Sousa Ana Chora
- Sousa Marta
- Sperry Alexandra
- Spinuzza Elisabetta
- Sriskandan Shiranee
- Stabler Sarah
- Staudinger Thomas
- Stecher Stephanie-Susanne
- Stienstra Ymkje
- Stiksrud Birgitte
- Stolz Eva
- Stone Amy
- Streinu-Cercel Adrian
- Streinu-Cercel Anca
- Stuart Ami
- Stuart David
- Suen Gabriel
- Suen Jacky Y.
- Sultana Asfia
- Summers Charlotte
- Supic Dubravka
- Surovcová Magdalena
- Svistunov Andrey
- Syrigos Konstantinos
- Sztajnbok Jaques
- Szuldrzynski Konstanty
- Tabrizi Shirin
- Taccone Fabio S.
- Tagherset Lysa
- Taleb Sara
- Talsma Jelmer
- Tamlihat Younes Ait
- Tampubolon Maria Lawrensia
- Tanaka Hiroyuki
- Taqdees Huda
- Taqi Arshad
- Tardivon Coralie
- Tattevin Pierre
- Taufik M. Azhari
- Tawfik Hassan
- Tedder Richard S.
- Teixeira João
- Tejada Sofia
- Tellier Marie-Capucine
- Terpstra Pleun
- Terrier Olivier
- Terzi Nicolas
- Tessier-Grenier Hubert
- Tey Adrian
- Thakur Anand
- Thibault Vincent
- Thiberville Simon-Djamel
- Thill Benoît
- Thompson Shaun
- Thomson David
- Thomson Emma C.
- Thwaites Ryan S.
- Tierney Paul
- Tieroshyn Vadim
- Timashev Peter S.
- Timsit Jean-François
- Tissot Noémie
- Toki Maria
- Tonby Kristian
- Torre Marta
- Torres Antoni
- Torres Margarida
- Torres-Zevallos Hernando
- Towers Michael
- Trapani Tony
- Treoux Théo
- Tromeur C. cile
- Trontzas Ioannis
- Trouillon Tiffany
- Truong Jeanne
- Tual Christelle
- Tubiana Sarah
- Tuite Helen
- Turmel Jean-Marie
- Turtle Lance C. W.
- Twardowski Pawel
- Téoulé François
- Uchiyama Makoto
- Udayanga P. G. Ishara
- Udy Andrew
- Ullrich Roman
- Uribe Alberto
- Usman Asad
- Uva Maria Sousa
- Uyeki Timothy M.
- Vajdovics Cristinava
- Val-Flores Luís
- Valran Amélie
- van de Velde Stijn
- van den Berge Marcel
- van der Palen Job
- van der Valk Paul
- van der Vekens Nicky
- van der Voort Peter
- van der Werf Sylvie
- van Gulik Laura
- van Hattem Jarne
- van Netten Carolien
- van Veen Ilonka
- Vanel Noémie
- Vanoverschelde Henk
- Varghese Pooja
- Vasconcelos Malte Kohns
- Vauchy Charline
- Vecham Pavan Kumar
- Veislinger Aurélie
- Vencken Sebastian
- Ventura Sara
- Verbon Annelies
- Vickers James
- Vidal José Ernesto
- Vieira C. sar
- Vijayan Deepak
- Vijayaraghavan Bharath Kumar Tirupakuzhi
- Vijayaraghavan Bharath Kumar Tirupakuzhi
- Villanueva Joy Ann
- Villar Judit
- Villeneuve Pierre-Marc
- Villoldo Andrea
- Visseaux Benoit
- Visser Hannah
- Vitiello Chiara
- Vonkeman Harald
- Vuotto Fanny
- Wang Chih-Hsien
- Webb Steve
- Wei Jia
- Weil Katharina
- Wesselius Sanne
- West T. Eoin
- Wham Murray
- Whelan Bryan
- White Nicole
- Wicky Paul Henri
- Wiedemann Aurélie
- Wijaya Surya Otto
- Wille Keith
- Willems Suzette
- Williams Virginie
- Wils Evert-Jan
- Wong Calvin
- Xynogalas Ioannis
- Yamazaki Masaki
- Yazdanpanah Yazdan
- Yelnik C. cile
- Yerkovich Stephanie
- Yiu Ng Wing
- Yokoyama Toshiki
- Yonis Hodane
- Yousif Obada
- Yuliarto Saptadi
- Zaaqoq Akram
- Zabbe Marion
- Zahran Maram
- Zambon Maria
- Zanella Alberto
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/12/2022
- Field of study
Background: Up to 30% of hospitalised patients with COVID-19 require advanced respiratory support, including high-flow nasal cannulas (HFNC), non-invasive mechanical ventilation (NIV), or invasive mechanical ventilation (IMV). We aimed to describe the clinical characteristics, outcomes and risk factors for failing non-invasive respiratory support in patients treated with severe COVID-19 during the first two years of the pandemic in high-income countries (HICs) and low middle-income countries (LMICs). Methods: This is a multinational, multicentre, prospective cohort study embedded in the ISARIC-WHO COVID-19 Clinical Characterisation Protocol. Patients with laboratory-confirmed SARS-CoV-2 infection who required hospital admission were recruited prospectively. Patients treated with HFNC, NIV, or IMV within the first 24 h of hospital admission were included in this study. Descriptive statistics, random forest, and logistic regression analyses were used to describe clinical characteristics and compare clinical outcomes among patients treated with the different types of advanced respiratory support. Results: A total of 66,565 patients were included in this study. Overall, 82.6% of patients were treated in HIC, and 40.6% were admitted to the hospital during the first pandemic wave. During the first 24 h after hospital admission, patients in HICs were more frequently treated with HFNC (48.0%), followed by NIV (38.6%) and IMV (13.4%). In contrast, patients admitted in lower- and middle-income countries (LMICs) were less frequently treated with HFNC (16.1%) and the majority received IMV (59.1%). The failure rate of non-invasive respiratory support (i.e. HFNC or NIV) was 15.5%, of which 71.2% were from HIC and 28.8% from LMIC. The variables most strongly associated with non-invasive ventilation failure, defined as progression to IMV, were high leukocyte counts at hospital admission (OR [95%CI]; 5.86 [4.83–7.10]), treatment in an LMIC (OR [95%CI]; 2.04 [1.97–2.11]), and tachypnoea at hospital admission (OR [95%CI]; 1.16 [1.14–1.18]). Patients who failed HFNC/NIV had a higher 28-day fatality ratio (OR [95%CI]; 1.27 [1.25–1.30]). Conclusions: In the present international cohort, the most frequently used advanced respiratory support was the HFNC. However, IMV was used more often in LMIC. Higher leucocyte count, tachypnoea, and treatment in LMIC were risk factors for HFNC/NIV failure. HFNC/NIV failure was related to worse clinical outcomes, such as 28-day mortality. Trial registration This is a prospective observational study; therefore, no health care interventions were applied to participants, and trial registration is not applicable
Association of Country Income Level With the Characteristics and Outcomes of Critically Ill Patients Hospitalized With Acute Kidney Injury and COVID-19
- Author
- Abdukahil heryl Ann
- Abdulkadir Nurul Najmee
- Abe Ryuzo
- Abel Laurent
- Abrous Amal
- Absil Lara
- Acker Andrew
- Adachi Shingo
- Adrião Diana
- Ahmed Shakeel
- Ainscough Kate
- Airlangga Eka
- Aisa Tharwat
- Akimoto Takako
- Akmal Ernita
- Akwani Chika
- Al Ageel Saleh
- Al Qasim Eman
- Al-dabbous Tala
- Al-Fares Abdulrahman
- Alalqam Razi
- Alberti Angela
- Alegesan Senthilkumar
- Alessi Marta
- Alex Beatrice
- Alexandre Kévin
- Alfoudri Huda
- Ali Imran
- Alidjnou Kazali Enagnon
- Aliudin Jeffrey
- Alkhafajee Qabas
- Allavena Clotilde
- Allou Nathalie
- Alves João
- Alves João Melo
- Alves Rita
- Amaral Maria
- Amira Nur
- Ampaw Phoebe
- Andini Roberto
- Andrey
- Andréjak Claire
- Angheben Andrea
- Angoulvant François
- Ansart Séverine
- Anthonidass Sivanesen
- Antonelli Massimo
- Antunes de Brito Carlos Alexandre
- Apriyana Ardiyan
- Arabi Yaseen
- Aragao Irene
- Arancibia Francisco
- Araujo Carolline
- Arcadipane Antonio
- Archambault Patrick
- Arenz Lukas
- Arlet Jean-Benoît
- Arnold-Day Christel
- Arora Lovkesh
- Arora Rakesh
- Artaud-Macari Elise
- Aryal Diptesh
- Asensio Angel
- Ashraf Muhammad
- Assie Jean Baptiste
- Asyraf Amirul
- Atif Minahel
- Atikah Ahmad Ridzuan Siti Nurul
- Atique Anika
- Auchabie Johann
- Aumaitre Hugues
- Auvet Adrien
- Ayadi Kamaluddin Muhammad Aisar
- Azemar Laurène
- Azoulay Cecile
- Bach Benjamin
- Bachelet Delphine
- Badr Claudine
- Baillie J. Kenneth
- Baird J Kevin
- Bak Erica
- Bakakos Agamemnon
- Bakar Nazreen Abu
- Bal Andriy
- Balakrishnan Mohanaprasanth
- Balan Valeria
- Balazote Pablo Serrano
- Bani-Sadr Firouzé
- Barbalho Renata
- Barbosa Nicholas Yuri
- Barclay Wendy S.
- Barnett Saef Umar
- Barnikel Michaela
- Barrelet Audrey
- Barrigoto Cleide
- Barrio Noelia García
- Bartoli Marie
- Baruch Joaquín
- Basmaci Romain
- Bassi Gianluigi Li
- Battaglini Denise
- Bauer Jules
- Bautista Rincon Diego Fernando
- Beane Abigail
- Bedossa Alexandra
- Bee Ker Hong
- Begum Husna
- Behilill Sylvie
- Beishuizen Albertus
- Bekken Gry Kloumann
- Beljantsev Aleksandr
- Bellemare David
- Beltrame Anna
- Beltrão Beatriz Amorim
- Beluze Marine
- Benech Nicolas
- Benjiman Lionel Eric
- Benkerrou Dehbia
- Bennett Suzanne
- Benny Binny
- Bento Luís
- Berdal Jan-Erik
- Bergeaud Delphine
- Bergin Hazel
- Bermejo Carlos Lumbreras
- Bernal Sobrino José Luis
- Bertoli Giulia
- Bertolino Lorenzo
- Bessis Simon
- Bevilcaqua Sybille
- Bezulier Karine
- Bhatt Amar
- Bhavsar Krishna
- Bianco Claudia
- Bidin Farah Nadiah
- Bin Kamarudin Mohd Nazlin
- Binti Mohd Yakop Siti Rohani
- Binti Zaidan Nor Zaila
- Bisoffi Zeno
- Bissuel François
- Biston Patrick
- Bitker Laurent
- Bitton Jonathan
- Blanco-Schweizer Pablo
- Blier Catherine
- Bloos Frank
- Blot Mathieu
- Blumberg Lucille
- Boccia Filomena
- Bodenes Laetitia
- Bogaert Debby
- Boivin Anne-Hélène
- Bolaños Isabela
- Bolze Pierre-Adrien
- Bompart François
- Borges Diogo
- Borie Raphaël
- Botelho-Nevers Elisabeth
- Bouadma Lila
- Bouchaud Olivier
- Bouchez Sabelline
- Bouhmani Dounia
- Bouhour Damien
- Bouiller Kévin
- Bouillet Laurence
- Bouisse Camile
- Boureau Anne-Sophie
- Bourke John
- Bouscambert Maude
- Bousquet Aurore
- Bouziotis Jason
- Boxma Bianca
- Boyer-Besseyre Marielle
- Boylan Maria
- Bozza Fernando Augusto
- Braconnier Axelle
- Braga Cynthia
- Brazzi Luca
- Breen Dorothy
- Breen Patrick
- Brewster David
- Brickell Kathy
- Brien Fionnuala O.
- Browne Shaunagh
- Brusse-Keizer Marjolein
- Bryda Petra
- Buchtele Nina
- Bugaeva Polina
- Buisson Marielle
- Burhan Erlina
- Burrell Aidan
- Bustos Ingrid G.
- Butnaru Denis
- Cabie André
- Cabral Susana
- Cabrita Joana Alves
- Caceres Eder
- Cadoz Cyril
- Callaghan Annmarie O.
- Calligy Kate
- Calvache Jose Andres
- Campana Valentine
- Campbell Paul
- Campisi Josie
- Camões João
- Cantero Mireia
- Caraux-Paz Pauline
- Cardellino Chiara Simona
- Cardoso Filipa
- Cardoso Filipe
- Cardoso Nelson
- Cardoso Sofia
- Carelli Simone
- Carlier Nicolas
- Carmoi Thierry
- Carney Gayle
- Carqueja Inês
- Carret Marie-Christine
- Carrier François Martin
- Carroll Ida
- Carson Gail
- Casanova Maire-Laure
- Cascão Mariana
- Casey Siobhan
- Casimiro José
- Cassandra Bailey
- Castanheira Nidyanara
- Castor-Alexandre Guylaine
- Castro Ivo
- Catarino Ana
- Catherine François-Xavier
- Cattaneo Paolo
- Cavalin Roberta
- Cavayas Alexandros
- Cely Lina Morales
- Cervantes-Gonzalez Minerva
- Chair Anissa
- Chakveatze Catherine
- Chan Adrienne
- Chand Meera
- Chantalat Auger Christelle
- Chapplain Jean-Marc
- Charpentier Charlotte
- Chas Julie
- Chavez-Iniquez Jonathan Samuel
- Che Kamaruddin Zul Amali
- Chen Anjellica
- Chen Yih-Sharng
- Chenard Léo
- Cheng Matthew Pellan
- Cheret Antoine
- Chia Jack Song
- Chiarabini Thibault
- Chica Julian
- Chidambaram Suresh Kumar
- Chirouze Catherine
- Chiumello Davide
- Cho Sung-Min
- Choileain Orna Ni
- Cholley Bernard
- Chopin Marie-Charlotte
- Chow Ting Soo
- Chow Yock Ping
- Chua Hiu Jian
- Chua Jonathan
- Chávez Iñiguez Jonathan Samuel
- Cidade Jose Pedro
- Citarella Barbara Wanjiru
- Citarella Barbara Wanjiru
- Ciullo Anna
- Clarke Jennifer
- Claure-Del Granado Rolando
- Claure-Del Granado Rolando
- Clohisey Sara
- Cobb Perren J.
- Codan Cassidy
- Cody Caitriona
- Coelho Alexandra
- Coles Jennifer
- Coles Megan
- Colin Gwenhaël
- Collins Michael
- Colombo Sebastiano Maria
- Combs Pamela
- Connolly Jennifer
- Connor Marie
- Conrad Anne
- Conway Elaine
- Cooke Graham S.
- Copland Mary
- Cordel Hugues
- Corley Amanda
- Cornelis Sabine
- Cornet Alexander Daniel
- Corpuz Arianne Joy
- Cortegiani Andrea
- Corvaisier Grégory
- Couffignal Camille
- Couffin-Cadiergues Sandrine
- Courtois Roxane
- Cousse Stéphanie
- Croonen Sabine
- Crowl Gloria
- Crump Jonathan
- Cruz Bermúdez Juan Luis
- Cruz Claudina
- Csete Marc
- Cullen Ailbhe
- Curley Gerard
- Curlier Elodie
- Curran Colleen
- Custodio Paula
- D'Ortenzio Eric
- da Silva Filipe Ana
- Da Silva Fernanda Dias
- Da Silveira Charlene
- Dabaliz Al-Awwab
- Dagens Andrew
- Dahly Darren
- Dai Danyang
- Dai Danyang
- Dalton Heidi
- Dalton Jo
- Daly Seamus
- Damas Juliana
- Daneman Nick
- Daniel Corinne
- Dankwa Emmanuelle A.
- Dantas Jorge
- de Loughry Gillian
- De Montmollin Etienne
- De Rosa Rosanna
- de Silva Thushan
- de Vries Peter
- Dean David
- Debard Alexa
- DeBenedictis Bianca
- Debray Marie-Pierre
- DeCastro Nathalie
- Dechert William
- Deconninck Lauren
- Decours Romain
- Defous Eve
- Delacroix Isabelle
- Delaveuve Eric
- Delavigne Karen
- Dell'Amore Andrea
- Delmas Christelle
- Delobel Pierre
- Delsing Corine
- Demonchy Elisa
- Denis Emmanuelle
- Deplanque Dominique
- Depuydt Pieter
- Desai Mehul
- Descamps Diane
- Desvallées Mathilde
- Devouge Eglantine Ferrand
- Dewayanti Santi
- Dhanger Pathik
- Diallo Alpha
- Diamantis Sylvain
- Diaz Juan Jose
- Diaz Rodrigo
- Didier Kévin
- Diehl Jean-Luc
- Dieperink Wim
- Dimet Jérôme
- Dinot Vincent
- Diop Fara
- Diouf Alphonsine
- Dishon Yael
- Djossou Félix
- Docherty Annemarie B.
- Doherty Helen
- Donnelly Christl A.
- Donnelly Maria
- Donohue Chloe
- Donohue Sean
- Donohue Yoann
- Doran Peter
- Dorival Céline
- Douglas James Joshua
- Dournon Nathalie
- Downer Triona
- Downey Joanne
- Downing Mark
- Drake Tom
- Driscoll Aoife
- Dryden Murray
- Dubee Vincent
- Dubos François
- Ducancelle Alexandre
- Duculan Toni
- Dudman Susanne
- Duggal Abhijit
- Dunand Paul
- Dunning Jake
- Duplaix Mathilde
- Durante-Mangoni Emanuele
- Durham Lucian
- Dussol Bertrand
- Duthoit Juliette
- Duval Xavier
- Dyrhol-Riise Anne Margarita
- Ean Sim Choon
- Echeverria-Villalobos Marco
- Edwards Eleanor
- Egan Siobhan
- El Sanharawi Mohammed
- Elapavaluru Subbarao
- Elharrar Brigitte
- Eliza Mohamed Nik Nur
- Eloy Philippine
- Elshazly Tarek
- Enderle Isabelle
- Endo Tomoyuki
- Eng Chan Chee
- Engelmann Ilka
- Enouf Vincent
- Epaulard Olivier
- Escher Martina
- Esperatti Mariano
- Esperou Hélène
- Esposito-Farese Marina
- Estevão João
- Etienne Manuel
- Ettalhaoui Nadia
- Everding Anna Greti
- Evers Mirjam
- Fabre Isabelle
- Fabre Marc
- Faheem Amna
- Fahy Arabella
- Fairfield Cameron J.
- Faria Pedro
- Fateena Hanan
- Fatoni Arie Zainul
- Faure Karine
- Favory Raphaël
- Fayed Mohamed
- Feely Niamh
- Feeney Laura
- Fernandes Jorge
- Fernandes Marília Andreia
- Fernandes Susana
- Ferrand François-Xavier
- Ferraz Mário
- Ferreira Benigno
- Ferreira Bernardo
- Ferreira Sílvia
- Ferriere Nicolas
- Ferrão Joana
- Ficko Céline
- Figueiredo-Mello Claudia
- Fiorda Juan
- Flament Thomas
- Flanagan Emily
- Flateau Clara
- Fletcher Tom
- Florence Aline-Marie
- Florio Letizia Lucia
- Flynn Deirdre
- Foley Jean
- Fomin Victor
- Fonseca Claudio Duarte
- Fonseca Tatiana
- Forsyth Simon
- Foster Denise
- Foti Giuseppe
- Fourn Erwan
- Fowler Robert A.
- Fraher Marianne
- Franch-Llasat Diego
- Fraser Christophe
- Fraser John F.
- Freire Marcela Vieira
- Freitas de Oliveira França Rafael
- Friedrich Caren
- Fritz Ricardo
- Fry Stéphanie
- Fuentes Nora
- Fukuda Masahiro
- G Argin
- Gaborieau Valérie
- Gaci Rostane
- Gagliardi Massimo
- Gagnard Jean-Charles
- Gagneux-Brunon Amandine
- Gaião Sérgio
- Gallagher Phil
- Gamble Carrol
- Gandonniere Charlotte Salmon
- Gani Yasmin
- Garan Arthur
- Garcia Rebekha
- Garcia-Gallo Esteban
- Garcês Rui Caetano
- Garot Denis
- Garrait Valérie
- Gault Nathalie
- Gavin Aisling
- Gavrylov Anatoliy
- Gaymard Alexandre
- Gebauer Johannes
- Geraud Eva
- Germano Nuno
- Ghadimi Moji
- Ghosn Jade
- Giani Marco
- Gibson Jess
- Gigante Tristan
- Gilg Morgane
- Gilroy Elaine
- Giordano Guillermo
- Girvan Michelle
- Gissot Valérie
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- Tawfik Hassan
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- Tho Leong Chin
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- Thomson David
- Thomson Emma C.
- Thorpe Mathew
- Thwaites Ryan S.
- Tierney Paul
- Tieroshyn Vadim
- Timashev Peter S.
- Timsit Jean-François
- Tirupakuzhi Vijayaraghavan Bharath Kumar
- Tissot Noémie
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- Turgeon Alexis F.
- Turmel Jean-Marie
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- Tveita Anders
- Twardowski Pawel
- Téoulé François
- Udy Andrew
- Ullrich Roman
- Uribe Alberto
- Usman Asad
- Uva Maria Sousa
- Uyeki Timothy M.
- Vajdovics Cristinava
- Val-Flores Luís
- Valran Amélie
- Van de Velde Stijn
- van den Berge Marcel
- van der Palen Job
- van der Valk Paul
- Van Der Vekens Nicky
- Van der Voort Peter
- Van Der Werf Sylvie
- van Gulik Laura
- Van Hattem Jarne
- van Netten Carolien
- van Veen Ilonka
- Vanel Noémie
- Vanoverschelde Henk
- Varghese Pooja
- Varrone Michael
- Vasudayan Shoban Raj
- Vauchy Charline
- Vecham Pavan Kumar
- Veeran Shaminee
- Veislinger Aurélie
- Vencken Sebastian
- Ventura Sara
- Verbon Annelies
- Vidal José Ernesto
- Vieira César
- Villanueva Joy Ann
- Villoldo Andrea
- Visseaux Benoit
- Vitiello Chiara
- Vonkeman Harald
- Vuotto Fanny
- Wahab Noor Hidayu
- Wahab Suhaila Abdul
- Wahid Nadirah Abdul
- Wainstein Marina
- Wainstein Marina
- Walsh Laura
- Wang Chih-Hsien
- Webb Steve
- Wei Jia
- Wen Tan Pei
- Wesselius Sanne
- Wham Murray
- Whelan Bryan
- White Nicole
- Wicky Paul Henri
- Wiedemann Aurélie
- Wijaya Surya Otto
- Wille Keith
- Willems Sue
- Williams Bailey
- Williams Patricia J.
- Williams Virginie
- Wils Evert-Jan
- Wittman Jessica
- Wong Calvin
- Wong Teck Fung
- Wong Xin Ci
- Wong Yew Sing
- Xian Gan Ee
- Xian Lim Saio
- Xynogalas Ioannis
- Yamazaki Masaki
- Yang Toh Jordan Zhien
- Yarad Elizabeth
- Yazdanpanah Yazdan
- Yelnik Cécile
- Yeoh Chian Hui
- Yerkovich Stephanie
- Yokoyama Toshiki
- Yonis Hodane
- Yousif Obada
- Zaaqoq Akram
- Zabbe Marion
- Zahid Masliza
- Zahran Maram
- Zambon Maria
- Zambrano Miguel
- Zanella Alberto
- Zaynah Nurul
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- Elsevier BV
- Publication date
- 26/05/2023
- Field of study
Introduction: Acute kidney injury (AKI) has been identified as one of the most common and significant problems in hospitalized patients with COVID-19. However, studies examining the relationship between COVID-19 and AKI in low- and low-middle income countries (LLMIC) are lacking. Given that AKI is known to carry a higher mortality rate in these countries, it is important to understand differences in this population. Methods: This prospective, observational study examines the AKI incidence and characteristics of 32,210 patients with COVID-19 from 49 countries across all income levels who were admitted to an intensive care unit during their hospital stay. Results: Among patients with COVID-19 admitted to the intensive care unit, AKI incidence was highest in patients in LLMIC, followed by patients in upper-middle income countries (UMIC) and high-income countries (HIC) (53%, 38%, and 30%, respectively), whereas dialysis rates were lowest among patients with AKI from LLMIC and highest among those from HIC (27% vs. 45%). Patients with AKI in LLMIC had the largest proportion of community-acquired AKI (CA-AKI) and highest rate of in-hospital death (79% vs. 54% in HIC and 66% in UMIC). The association between AKI, being from LLMIC and in-hospital death persisted even after adjusting for disease severity. Conclusions: AKI is a particularly devastating complication of COVID-19 among patients from poorer nations where the gaps in accessibility and quality of healthcare delivery have a major impact on patient outcomes
Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective, multinational, observational study
- Author
- Abbas Ali
- Abdukahil Sheryl Ann
- Abe Ryuzo
- Abel Laurent
- Abreu Julia Rodriguez
- Absil Lara
- Acharya Subhash
- Acker Andrew
- Adrião Diana
- Ahmed Shakeel
- Ainscough Kate
- Aisa Tharwat
- Akimoto Takako
- Akmal Ernita
- Al Ageel Saleh
- Al Qasim Eman
- Al-dabbous Tala
- Al-Fares Abdulrahman
- Alalqam Razi
- Alegesan Senthilkumar
- Alegre Cynthia
- Alessi Marta
- Alex Beatrice
- Alexandre Kévin
- Alfoudri Huda
- Ali Imran
- Alidjnou Kazali Enagnon
- Aliudin Jeffrey
- Alkhafajee Qabas
- Allavena Clotilde
- Allou Nathalie
- Altaf Aneela
- Alves João
- Alves João Melo
- Alves Rita
- Amaral Maria
- Ampaw Phoebe
- Andini Roberto
- Andréjak Claire
- Angheben Andrea
- Angoulvant François
- Ansart Séverine
- Antonelli Massimo
- Apriyana Ardiyan
- Arabi Yaseen
- Aragao Irene
- Araujo Carolline
- Arcadipane Antonio
- Archambault Patrick
- Arenz Lukas
- Arlet Jean-Benoît
- Arnold-Day Christel
- Arora Lovkesh
- Arora Rakesh
- Artaud-Macari Elise
- Aryal Diptesh
- Aryal Diptesh
- Asensio Angel
- Asif Namra
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- de Brito Carlos Alexandre Antunes
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- de Oliveira França Rafael Freitas
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- Doherty Helen
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- Dondorp Arjen M.
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- Greene Courtney
- Greenhalf William
- Greffe Segolène
- Grieco Domenico Luca
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- Gu Yusing
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- Hssain Ali Ait
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- Hussain Iqbal
- Ibáñez-Prada Elsa D.
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- Kho Michelle E.
- Khoo Saye
- Khoso Nasir
- Kida Yuri
- Kiiza Peter
- Kildal Anders Benjamin
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- Kindgen-Milles Detlef
- Kitamura Nobuya
- Klenerman Paul
- Klont Rob
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- Kobbe Robin
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- Lachatre Marie
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- Laffey John G.
- Lagrange Marie
- Laine Fabrice
- Lairez Olivier
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- Lee James
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- Leeming Gary
- Lefebvre Bénédicte
- Lefebvre Laurent
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- Loschner Anthony L.
- Loubet Paul
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- Marsh Brian
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- Marshall John C.
- Martelli Celina Turchi
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- Martin-Blondel Guillaume
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- Olliaro Piero L.
- Ong David S. Y.
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- Pagadoy Maïder
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- Prinssen Anton
- Pritchard Mark G.
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- Revest Matthieu
- Rewa Oleksa
- Reyes Luis Felipe
- Reyes Tiago
- Ribeiro Ana Freitas
- Ribeiro Maria Ines
- Richardson David
- Richardson Denise
- Richier Laurent
- Riera Jordi
- Rincon Diego Fernando Bautista
- Rios Ana L.
- Rishu Asgar
- Rispal Patrick
- Risso Karine
- Rizer Nicholas
- Robba Chiara
- Roberto André
- Roberts Stephanie
- Robertson David L.
- Robineau Olivier
- Roche-Campo Ferran
- Rodari Paola
- Rodeia Simão
- Roessler Bernhard
- Roger Pierre-Marie
- Rojek Amanda
- Rojo Jaime Cruz
- Romaru Juliette
- Roncon-Albuquerque Roberto
- Roriz Mélanie
- Rosa-Calatrava Manuel
- Rose Michael
- Rosenberger Dorothea
- Rossanese Andrea
- Rossetti Matteo
- Rossignol Bénédicte
- Rossignol Patrick
- Rousset Stella
- Roy Carine
- Roze Benoît
- Rusmawatiningtyas Desy
- Russell Clark D.
- Ryan Maeve
- Ryan Maria
- Ryckaert Steffi
- Rätsep Indrek
- Saba Isabela
- Sadaf Sairah
- Sadat Musharaf
- Sahraei Valla
- Saidani Nadia
- Saint-Gilles Maximilien
- Sakiyalak Pranya
- Salahuddin Nawal
- Salazar Leonardo
- Saleem Jodat
- Sales Gabriele
- Sallaberry Stéphane
- Salvator Hélène
- Sanchez Olivier
- Sanchez-Miralles Angel
- Sancho-Shimizu Vanessa
- Sandhu Gyan
- Sandhu Zulfiqar
- Sandrine Pierre-François
- Sandulescu Oana
- Sanharawi Mohammed El
- Sant Ceila Maria
- Santo Catarina Espírito
- Santos Marlene
- Santos Marta Leal
- Sarfo-Mensah Shirley
- Sarton Benjamine
- Satyapriya Sree
- Satyawati Rumaisah
- Saviciute Egle
- Schaffer Justin
- Schermer Tjard
- Scherpereel Arnaud
- Schneider Marion
- Schroll Stephan
- Schwameis Michael
- Scott Janet T.
- Scott-Brown James
- Sedillot Nicholas
- Seitz Tamara
- Selvanayagam Jaganathan
- Semaille Caroline
- Semedi Bambang Pujo
- Semple Malcolm G.
- Senneville Eric
- Sequeira Filipa
- Sequeira Tânia
- Shadowitz Ellen
- Shah Naseem Ali
- Shamsah Mohammad
- Sharjeel Shaikh
- Sharma Pratima
- Shaw Catherine A.
- Shaw Victoria
- Sheharyar Ashraf
- Shetty Rajesh Mohan
- Shi Haixia
- Shiekh Mohiuddin
- Shimizu Keiki
- Shrapnel Sally
- Shrestha Pramesh Sundar
- Shrestha Shubha Kalyan
- Shukeri Wan Fadzlina Wan Muhd
- Shum Hoi Ping
- Sibiude Jeanne
- Siddiqui Atif
- Sigfrid Louise
- Sikander Rana Imran
- Sillaots Piret
- Silva Catarina
- Silva Maria Joao
- Silva Rogério
- Sin Wai Ching
- Singh Budha Charan
- Singh Moirangthem Bikram
- Singh Punam
- Sitompul Pompini Agustina
- Skeie Linda Gail
- Skogen Vegard
- Smith Sue
- Smood Benjamin
- Smyth Coilin
- Smyth Michelle
- Smyth Michelle
- Snacken Morgane
- So Dominic
- Sobrino José Luis Bernal
- Solomon Joshua
- Solomon Tom
- Somers Emily
- Sommet Agnès
- Song Myung Jin
- Song Rima
- Song Tae
- Sotto Albert
- Soum Edouard
- Sousa Ana Chora
- Sousa Marta
- Sperry Alexandra
- Spinuzza Elisabetta
- Sriskandan Shiranee
- Stabler Sarah
- Staudinger Thomas
- Stecher Stephanie-Susanne
- Stienstra Ymkje
- Stiksrud Birgitte
- Stolz Eva
- Stone Amy
- Streinu-Cercel Adrian
- Streinu-Cercel Anca
- Stuart Ami
- Stuart David
- Suen Gabriel
- Suen Jacky Y.
- Sultana Asfia
- Summers Charlotte
- Supic Dubravka
- Surovcová Magdalena
- Svistunov Andrey
- Syrigos Konstantinos
- Sztajnbok Jaques
- Szuldrzynski Konstanty
- Tabrizi Shirin
- Taccone Fabio S.
- Tagherset Lysa
- Taleb Sara
- Talsma Jelmer
- Tamlihat Younes Ait
- Tampubolon Maria Lawrensia
- Tanaka Hiroyuki
- Taqdees Huda
- Taqi Arshad
- Tardivon Coralie
- Tattevin Pierre
- Taufik M. Azhari
- Tawfik Hassan
- Tedder Richard S.
- Teixeira João
- Tejada Sofia
- Tellier Marie-Capucine
- Terpstra Pleun
- Terrier Olivier
- Terzi Nicolas
- Tessier-Grenier Hubert
- Tey Adrian
- Thakur Anand
- Thibault Vincent
- Thiberville Simon-Djamel
- Thill Benoît
- Thompson Shaun
- Thomson David
- Thomson Emma C.
- Thwaites Ryan S.
- Tierney Paul
- Tieroshyn Vadim
- Timashev Peter S.
- Timsit Jean-François
- Tissot Noémie
- Toki Maria
- Tonby Kristian
- Torre Marta
- Torres Antoni
- Torres Margarida
- Torres-Zevallos Hernando
- Towers Michael
- Trapani Tony
- Treoux Théo
- Tromeur Cécile
- Trontzas Ioannis
- Trouillon Tiffany
- Truong Jeanne
- Tual Christelle
- Tubiana Sarah
- Tuite Helen
- Turmel Jean-Marie
- Turtle Lance C. W.
- Twardowski Pawel
- Téoulé François
- Uchiyama Makoto
- Udayanga P. G. Ishara
- Udy Andrew
- Ullrich Roman
- Uribe Alberto
- Usman Asad
- Uva Maria Sousa
- Uyeki Timothy M.
- Vajdovics Cristinava
- Val-Flores Luís
- Valran Amélie
- Van de Velde Stijn
- van den Berge Marcel
- van der Palen Job
- van der Valk Paul
- Van Der Vekens Nicky
- Van der Voort Peter
- Van Der Werf Sylvie
- van Gulik Laura
- Van Hattem Jarne
- van Netten Carolien
- van Veen Ilonka
- Vanel Noémie
- Vanoverschelde Henk
- Varghese Pooja
- Vasconcelos Malte Kohns
- Vauchy Charline
- Vecham Pavan Kumar
- Veislinger Aurélie
- Vencken Sebastian
- Ventura Sara
- Verbon Annelies
- Vickers James
- Vidal José Ernesto
- Vieira César
- Vijayan Deepak
- Vijayaraghavan Bharath Kumar Tirupakuzhi
- Vijayaraghavan Bharath Kumar Tirupakuzhi
- Villanueva Joy Ann
- Villar Judit
- Villeneuve Pierre-Marc
- Villoldo Andrea
- Visseaux Benoit
- Visser Hannah
- Vitiello Chiara
- Vonkeman Harald
- Vuotto Fanny
- Wang Chih-Hsien
- Webb Steve
- Wei Jia
- Weil Katharina
- Wesselius Sanne
- West T. Eoin
- Wham Murray
- Whelan Bryan
- White Nicole
- Wicky Paul Henri
- Wiedemann Aurélie
- Wijaya Surya Otto
- Wille Keith
- Willems Suzette
- Williams Virginie
- Wils Evert-Jan
- Wong Calvin
- Xynogalas Ioannis
- Yamazaki Masaki
- Yazdanpanah Yazdan
- Yelnik Cécile
- Yerkovich Stephanie
- Yiu Ng Wing
- Yokoyama Toshiki
- Yonis Hodane
- Yousif Obada
- Yuliarto Saptadi
- Zaaqoq Akram
- Zabbe Marion
- Zahran Maram
- Zambon Maria
- Zanella Alberto
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 13/09/2022
- Field of study
Background: Up to 30% of hospitalised patients with COVID-19 require advanced respiratory support, including high-flow nasal cannulas (HFNC), non-invasive mechanical ventilation (NIV), or invasive mechanical ventilation (IMV). We aimed to describe the clinical characteristics, outcomes and risk factors for failing non-invasive respiratory support in patients treated with severe COVID-19 during the first two years of the pandemic in high-income countries (HICs) and low middle-income countries (LMICs).
Methods: This is a multinational, multicentre, prospective cohort study embedded in the ISARIC-WHO COVID-19 Clinical Characterisation Protocol. Patients with laboratory-confirmed SARS-CoV-2 infection who required hospital admission were recruited prospectively. Patients treated with HFNC, NIV, or IMV within the first 24 h of hospital admission were included in this study. Descriptive statistics, random forest, and logistic regression analyses were used to describe clinical characteristics and compare clinical outcomes among patients treated with the different types of advanced respiratory support.
Results: A total of 66,565 patients were included in this study. Overall, 82.6% of patients were treated in HIC, and 40.6% were admitted to the hospital during the first pandemic wave. During the first 24 h after hospital admission, patients in HICs were more frequently treated with HFNC (48.0%), followed by NIV (38.6%) and IMV (13.4%). In contrast, patients admitted in lower- and middle-income countries (LMICs) were less frequently treated with HFNC (16.1%) and the majority received IMV (59.1%). The failure rate of non-invasive respiratory support (i.e. HFNC or NIV) was 15.5%, of which 71.2% were from HIC and 28.8% from LMIC. The variables most strongly associated with non-invasive ventilation failure, defined as progression to IMV, were high leukocyte counts at hospital admission (OR [95%CI]; 5.86 [4.83-7.10]), treatment in an LMIC (OR [95%CI]; 2.04 [1.97-2.11]), and tachypnoea at hospital admission (OR [95%CI]; 1.16 [1.14-1.18]). Patients who failed HFNC/NIV had a higher 28-day fatality ratio (OR [95%CI]; 1.27 [1.25-1.30]).
Conclusions: In the present international cohort, the most frequently used advanced respiratory support was the HFNC. However, IMV was used more often in LMIC. Higher leucocyte count, tachypnoea, and treatment in LMIC were risk factors for HFNC/NIV failure. HFNC/NIV failure was related to worse clinical outcomes, such as 28-day mortality. Trial registration This is a prospective observational study; therefore, no health care interventions were applied to participants, and trial registration is not applicable
Thrombotic and hemorrhagic complications of COVID-19 in adults hospitalized in high-income countries compared with those in adults hospitalized in low- and middle-income countries in an international registry
- Author
- Abdukahil Sheryl Ann
- Abdulkadir Nurul Najmee
- Abe Ryuzo
- Abel Laurent
- Abrous Amal
- Absil Lara
- Acker Andrew
- Adam Elisabeth
- Adrião Diana
- Ahmed Shakeel
- Ainscough Kate
- Aisa Tharwat
- Akimoto Takako
- Akmal Ernita
- Akwani Chika
- Al Ageel Saleh
- Al Qasim Eman
- Al-dabbous Tala
- Al-Fares Abdulrahman
- Alalqam Razi
- Alberti Angela
- Alegesan Senthilkumar
- Alessi Marta
- Alex Beatrice
- Alexander Peta MA
- Alexandre Kévin
- Alfoudri Huda
- Ali Imran
- Alidjnou Kazali Enagnon
- Aliudin Jeffrey
- Alkhafajee Qabas
- Allavena Clotilde
- Allou Nathalie
- Alves João
- Alves João Melo
- Alves Rita
- Amaral Maria
- Amira Nur
- Ampaw Phoebe
- Andini Roberto
- Andréjak Claire
- Angheben Andrea
- Angoulvant François
- Ansart Séverine
- Anthonidass Sivanesen
- Antonelli Massimo
- Apriyana Ardiyan
- Arabi Yaseen
- Aragao Irene
- Arancibia Francisco
- Araujo Carolline
- Arcadipane Antonio
- Archambault Patrick
- Arenz Lukas
- Arlet Jean-Benoît
- Arnold-Day Christel
- Arora Lovkesh
- Arora Rakesh
- Artaud-Macari Elise
- Aryal Diptesh
- Asensio Angel
- Ashraf Muhammad
- Assie Jean Baptiste
- Asyraf Amirul
- Atif Minahel
- Atikah Ahmad Ridzuan Siti Nurul
- Atique Anika
- Auchabie Johann
- Aumaitre Hugues
- Auvet Adrien
- Ayadi Kamaluddin Muhammad Aisar
- Azemar Laurène
- Azoulay Cecile
- Bach Benjamin
- Bachelet Delphine
- Badr Claudine
- Baig Nadia
- Baillie J Kenneth
- Bak Erica
- Bakakos Agamemnon
- Bakar Nazreen Abu
- Bal Andriy
- Balakrishnan Mohanaprasanth
- Balan Valeria
- Balazote Pablo Serrano
- Bani-Sadr Firouzé
- Barbalho Renata
- Barbosa Nicholas Yuri
- Barclay Wendy S
- Barnett Saef Umar
- Barnikel Michaela
- Barrasa Helena
- Barrelet Audrey
- Barrigoto Cleide
- Barrio Noelia García
- Bartoli Marie
- Baruch Joaquín
- Basmaci Romain
- Basri Muhammad Fadhli Hassin
- Bassi Gianluigi Li
- Battaglini Denise
- Bauer Jules
- Beane Abigail
- Bedossa Alexandra
- Begum Husna
- Behilill Sylvie
- Beishuizen Albertus
- Bekken Gry Kloumann
- Beljantsev Aleksandr
- Bellemare David
- Beltrame Anna
- Beltrão Beatriz Amorim
- Beluze Marine
- Benech Nicolas
- Benjiman Lionel Eric
- Benkerrou Dehbia
- Bennett Suzanne
- Benny Binny
- Bento Luís
- Berdal Jan-Erik
- Bergeaud Delphine
- Bergin Hazel
- Bermejo Carlos Lumbreras
- Bertoli Giulia
- Bertolino Lorenzo
- Bessis Simon
- Bevilcaqua Sybille
- Bezulier Karine
- Bhatt Amar
- Bhavsar Krishna
- Bianco Claudia
- Bidin Farah Nadiah
- Binti Mohd Yakop Siti Rohani
- Binti Zaidan Nor Zaila
- Bisoffi Zeno
- Bissuel François
- Bitker Laurent
- Bitton Jonathan
- Blanco-Schweizer Pablo
- Blier Catherine
- Bloos Frank
- Blot Mathieu
- Blumberg Lucille
- Boccia Filomena
- Bodenes Laetitia
- Bogaert Debby
- Boivin Anne-Hélène
- Bolaños Isabela
- Bolze Pierre-Adrien
- Bompart François
- Borges Diogo
- Borie Raphaël
- Bosse Hans Martin
- Botelho-Nevers Elisabeth
- Bouadma Lila
- Bouchaud Olivier
- Bouchez Sabelline
- Bouhmani Dounia
- Bouhour Damien
- Bouiller Kévin
- Bouillet Laurence
- Bouisse Camile
- Boureau Anne-Sophie
- Bourke John
- Bouscambert Maude
- Bousquet Aurore
- Bouziotis Jason
- Boxma Bianca
- Boyer-Besseyre Marielle
- Boylan Maria
- Bozza Fernando Augusto
- Bozza Patricia T
- Braconnier Axelle
- Braga Cynthia
- Brandenburger Timo
- Brazzi Luca
- Breen Dorothy
- Breen Patrick
- Brewster David
- Brickell Kathy
- Brien Fionnuala O
- Browne Alex
- Browne Shaunagh
- Brozzi Nicolas
- Brusse-Keizer Marjolein
- Bryda Petra
- Buchtele Nina
- Buisson Marielle
- Burhan Erlina
- Burrell Aidan
- Bustos Ingrid G
- Cabie André
- Cabral Susana
- Cabrita Joana Alves
- Caceres Eder
- Cadoz Cyril
- Callaghan Annmarie O
- Calligy Kate
- Calvache Jose Andres
- Campana Valentine
- Campbell Paul
- Campisi Josie
- Camões João
- Canepa Cecilia
- Cantero Mireia
- Caraux-Paz Pauline
- Cardellino Chiara Simona
- Cardoso Filipa
- Cardoso Filipe
- Cardoso Nelson
- Cardoso Sofia
- Carelli Simone
- Carlier Nicolas
- Carmoi Thierry
- Carney Gayle
- Carqueja Inês
- Carret Marie-Christine
- Carrier François Martin
- Carroll Ida
- Carson Gail
- Casanova Maire-Laure
- Cascão Mariana
- Casey Siobhan
- Casimiro José
- Cassandra Bailey
- Castanheira Nidyanara
- Castañeda Silvia
- Castor-Alexandre Guylaine
- Castro Ivo
- Catarino Ana
- Catherine François-Xavier
- Cattaneo Paolo
- Cavalin Roberta
- Cavayas Alexandros
- Cely Lina Morales
- Cervantes-Gonzalez Minerva
- Chair Anissa
- Chakveatze Catherine
- Chan Adrienne
- Chand Meera
- Chantalat Auger Christelle
- Chapplain Jean-Marc
- Charpentier Charlotte
- Chas Julie
- Che Kamaruddin Zul Amali
- Chen Anjellica
- Chen Yih-Sharng
- Chenard Léo
- Cheng Matthew Pellan
- Cheret Antoine
- Chia Jack Song
- Chiarabini Thibault
- Chica Julian
- Chidambaram Suresh Kumar
- Chin Tho Leong
- Chirouze Catherine
- Chiumello Davide
- Cho Sung-Min
- Cho Sung-Min
- Choileain Orna Ni
- Cholley Bernard
- Chopin Marie-Charlotte
- Chow Ting Soo
- Chua Hiu Jian
- Chua Jonathan
- Chávez Iñiguez Jonathan Samuel
- Cidade Jose Pedro
- Cisneros Herreros José Miguel
- Citarella Barbara Wanjiru
- Citarella Barbara Wanjiru
- Ciullo Anna
- Clarke Emma
- Clarke Jennifer
- Claure-Del Granado Rolando
- Clohisey Sara
- Codan Cassidy
- Cody Caitriona
- Coelho Alexandra
- Coles Jennifer
- Coles Megan
- Colin Gwenhaël
- Collins Michael
- Colombo Sebastiano Maria
- Combs Pamela
- Connolly Jennifer
- Connor Marie
- Conrad Anne
- Conway Elaine
- Cooke Graham S
- Copland Mary
- Cordel Hugues
- Corley Amanda
- Cornelis Sabine
- Cornet Alexander Daniel
- Corpuz Arianne Joy
- Cortegiani Andrea
- Corvaisier Grégory
- Costigan Emma
- Couffignal Camille
- Couffin-Cadiergues Sandrine
- Courtois Roxane
- Cousse Stéphanie
- Cregan Rachel
- Cristella Cosimo
- Croonen Sabine
- Crowl Gloria
- Crump Jonathan
- Cruz Bermúdez Juan Luis
- Cruz Rojo Jaime
- Cruz Claudina
- Csete Marc
- Cullen Ailbhe
- Cummings Matthew
- Curley Gerard
- Curlier Elodie
- Curran Colleen
- Custodio Paula
- Cárcel Sheila
- D'Aragon Frédérick
- D'Ortenzio Eric
- da Silva Filipe Ana
- Da Silva Fernanda Dias
- Da Silveira Charlene
- Dabaliz Al-Awwab
- Dagens Andrew
- Dahly Darren
- Dalton Heidi
- Dalton Heidi
- Dalton Jo
- Daly Seamus
- Damas Juliana
- Daneman Nick
- Daniel Corinne
- Dankwa Emmanuelle A
- Dantas Jorge
- de Brito Carlos Alexandre Antunes
- de Castro Maisa Guimarães
- de Jong Menno
- de la Calle Guillermo Maestro
- de Loughry Gillian
- De Montmollin Etienne
- de Oliveira França Rafael Freitas
- de Piero Maria
- de Pinho Oliveira Ana Isabel
- De Rosa Rosanna
- de Silva Thushan
- de Vries Peter
- Dean David
- Debard Alexa
- DeBenedictis Bianca
- Debray Marie-Pierre
- DeCastro Nathalie
- Dechert William
- Deconninck Lauren
- Decours Romain
- Defous Eve
- Delacroix Isabelle
- Delaveuve Eric
- Delavigne Karen
- Delfos Nathalie M
- Deligiannis Ionna
- Dell'Amore Andrea
- Delmas Christelle
- Delobel Pierre
- Delsing Corine
- Demonchy Elisa
- Denis Emmanuelle
- Deplanque Dominique
- Depuydt Pieter
- Desai Mehul
- Descamps Diane
- Desvallées Mathilde
- Devouge Eglantine Ferrand
- Dewayanti Santi
- Dhanger Pathik
- Diallo Alpha
- Diamantis Sylvain
- Dias André
- Diaz Juan Jose
- Diaz Priscila
- Diaz Rodrigo
- Didier Kévin
- Diehl Jean-Luc
- Dieperink Wim
- Dimet Jérôme
- Dinot Vincent
- Diop Fara
- Diouf Alphonsine
- Dishon Yael
- Djossou Félix
- Docherty Annemarie B
- Doherty Helen
- Donnelly Christl A
- Donnelly Maria
- Donohue Chloe
- Donohue Sean
- Donohue Yoann
- Doran Peter
- Dorival Céline
- Douglas James Joshua
- Dournon Nathalie
- Downer Triona
- Downey Joanne
- Downing Mark
- Drake Tom
- Driscoll Aoife
- Dryden Murray
- Dubee Vincent
- Dubos François
- Ducancelle Alexandre
- Duculan Toni
- Dudman Susanne
- Duggal Abhijit
- Dunand Paul
- Dunning Jake
- Duplaix Mathilde
- Durante-Mangoni Emanuele
- Durham Lucian
- Dussol Bertrand
- Duthoit Juliette
- Duval Xavier
- Dyrhol-Riise Anne Margarita
- Ean Sim Choon
- Echeverria-Villalobos Marco
- Eddington Devin P
- Egan Siobhan
- Eira Carla
- Ekow Harrison Samuel Bernard
- El Sanharawi Mohammed
- Elapavaluru Subbarao
- Elharrar Brigitte
- Eliza Mohamed Nik Nur
- Ellerbroek Jacobien
- Eloy Philippine
- Elshazly Tarek
- Enderle Isabelle
- Endo Tomoyuki
- Eng Chan Chee
- Engelmann Ilka
- Enouf Vincent
- Epaulard Olivier
- Escher Martina
- Esperatti Mariano
- Esperou Hélène
- Esposito-Farese Marina
- Estevão João
- Etienne Manuel
- Ettalhaoui Nadia
- Everding Anna Greti
- Evers Mirjam
- Fabre Isabelle
- Fabre Marc
- Faheem Amna
- Fahy Arabella
- Fairfield Cameron J
- Fanning Jonathon P
- Faria Pedro
- Fateena Hanan
- Fatoni Arie Zainul
- Faure Karine
- Favory Raphaël
- Fayed Mohamed
- Feely Niamh
- Feeney Laura
- Fernandes Jorge
- Fernandes Marília Andreia
- Fernandes Susana
- Ferrand François-Xavier
- Ferraz Mário
- Ferreira Benigno
- Ferreira Bernardo
- Ferreira Isabel
- Ferreira Sílvia
- Ferriere Nicolas
- Ferrão Joana
- Ficko Céline
- Figueiredo-Mello Claudia
- Fiorda Juan
- Flament Thomas
- Flateau Clara
- Fletcher Tom
- Florence Aline-Marie
- Florio Letizia Lucia
- Flynn Deirdre
- Foley Claire
- Foley Jean
- Fonseca Claudio Duarte
- Fonseca Tatiana
- Forsyth Simon
- Foster Denise
- Foti Giuseppe
- Fourn Erwan
- Fowler Robert A
- Fraher Marianne
- Franch-Llasat Diego
- Fraser Christophe
- Fraser John
- Fraser John F
- Freire Marcela Vieira
- Fritz Ricardo
- Fry Stéphanie
- Fuentes Nora
- Fukuda Masahiro
- Gaborieau Valérie
- Gaci Rostane
- Gagliardi Massimo
- Gagnard Jean-Charles
- Gagneux-Brunon Amandine
- Gaião Sérgio
- Gallagher Phil
- Gamble Carrol
- Gandonniere Charlotte Salmon
- Gani Yasmin
- Garan Arthur
- Garcia Rebekha
- Garcia-Gallo Esteban
- Garcês Rui Caetano
- Garot Denis
- Garrait Valérie
- Gault Nathalie
- Gavin Aisling
- Gavrylov Anatoliy
- Gaymard Alexandre
- Gebauer Johannes
- Geraud Eva
- Germano Nuno
- Ghosn Jade
- Giani Marco
- Gibson Jess
- Gigante Tristan
- Gilg Morgane
- Gilroy Elaine
- Giordano Guillermo
- Girvan Michelle
- Gissot Valérie
- Glikman Daniel
- Gnall Eric
- Goehringer François
- Goepel Siri
- Goffard Jean-Christophe
- Goh Jin Yi
- Golob Jonathan
- Gominet Marie
- Gonzalez Alicia
- González Víctor Quirós
- Gordon Patricia
- Gorenne Isabelle
- Gormley Conor
- Goubert Laure
- Goujard Cécile
- Goulenok Tiphaine
- Grable Margarite
- Graf Jeronimo
- Grandin Edward Wilson
- Granerud Beathe Kiland
- Granier Pascal
- Grasselli Giacomo
- Green Christopher A
- Greene Courtney
- Greenhalf William
- Greffe Segolène
- Grieco Domenico Luca
- Griffee Matthew
- Griffee Matthew J
- Griffiths Fiona
- Grigoras Ioana
- Groenendijk Albert
- Gruner Heidi
- Gu Yusing
- Guedj Jérémie
- Guego Martin
- Guellec Dewi
- Guerreiro Daniela
- Guery Romain
- Guillaumot Anne
- Guilleminault Laurent
- Guimard Thomas
- Gómez-Junyent Joan
- Haalboom Marieke
- Haber Daniel
- Habraken Hannah
- Hachemi Ali
- Hadri Nadir
- Haji Ab Rahman Ahmad Kashfi
- Hakak Sheeba
- Hall Adam
- Hall Matthew
- Halpin Sophie
- Hamer Ansley
- Hamidfar Rebecca
- Hammond Naomi
- Hammond Terese
- Han Lim Yuen
- Haniffa Rashan
- Hao Kok Wei
- Hardwick Hayley
- Harrison Ewen M
- Harrison Janet
- Hartman Alan
- Hashmi Junaid
- Hayes Ailbhe
- Hays Leanne
- Heerman Jan
- Heggelund Lars
- Hendry Ross
- Hennessy Martina
- Henriquez-Trujillo Aquiles
- Hentzien Maxime
- Hernandez Diana
- Hernandez-Montfort Jaime
- Hershey Andrew
- Hesstvedt Liv
- Higgins Dawn
- Higgins Eibhlin
- Higgins Rupert
- Hinchion Rita
- Hinton Samuel
- Hiraiwa Hiroaki
- Hitoto Hikombo
- Ho Antonia
- Ho Yi Bin
- Hoctin Alexandre
- Hoffmann Isabelle
- Hoh Wei Han
- Hoiting Oscar
- Holt Rebecca
- Holten Aleksander Rygh
- Holter Jan Cato
- Hong Bee Ker
- Horby Peter
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- Tveita Anders
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- Usman Asad
- Uva Maria Sousa
- Uyeki Timothy M
- Vajdovics Cristinava
- Val-Flores Luís
- Valran Amélie
- Van de Velde Stijn
- van den Berge Marcel
- Van der Feltz Machteld
- van der Palen Job
- van der Valk Paul
- Van Der Vekens Nicky
- Van der Voort Peter
- Van Der Werf Sylvie
- van Gulik Laura
- Van Hattem Jarne
- van Netten Carolien
- van Someren Gréve Frank
- van Veen Ilonka
- Van Willigen Hugo
- Vanel Noémie
- Vanoverschelde Henk
- Varghese Pooja
- Varrone Michael
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- Vasudayan Shoban Raj
- Vauchy Charline
- Vecham Pavan Kumar
- Veeran Shaminee
- Veislinger Aurélie
- Vencken Sebastian
- Ventura Sara
- Verbon Annelies
- Vidal José Ernesto
- Vieira César
- Villanueva Joy Ann
- Villar Judit
- Villeneuve Pierre-Marc
- Villoldo Andrea
- Visseaux Benoit
- Visser Hannah
- Vitiello Chiara
- Vonkeman Harald
- Vuotto Fanny
- Wahab Noor Hidayu
- Wahab Suhaila Abdul
- Wahid Nadirah Abdul
- Wainstein Marina
- Walsh Laura
- Wang Chih-Hsien
- Webb Steve
- Wei Jia
- Weil Katharina
- Wen Tan Pei
- Wesselius Sanne
- Wham Murray
- Whelan Bryan
- White Nicole
- Wicky Paul Henri
- Wiedemann Aurélie
- Wijaya Surya Otto
- Wille Keith
- Willems Sue
- Williams Bailey
- Williams Patricia J
- Williams Virginie
- Wils Evert-Jan
- Wittman Jessica
- Wong Calvin
- Wong Teck Fung
- Wong Xin Ci
- Wong Yew Sing
- Xian Gan Ee
- Xian Lim Saio
- Xynogalas Ioannis
- Yamazaki Masaki
- Yang Toh Jordan Zhien
- Yarad Elizabeth
- Yazdanpanah Yazdan
- Yelnik Cécile
- Yeoh Chian Hui
- Yerkovich Stephanie
- Yokoyama Toshiki
- Yonis Hodane
- Yousif Obada
- Zaaqoq Akram
- Zabbe Marion
- Zacharowski Kai
- Zahid Masliza
- Zahran Maram
- Zambon Maria
- Zambrano Miguel
- Zanella Alberto
- Zaynah Nurul
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- Elsevier BV
- Publication date
- 30/06/2023
- Field of study
Background: COVID-19 has been associated with a broad range of thromboembolic, ischemic, and hemorrhagic complications (coagulopathy complications). Most studies have focused on patients with severe disease from high-income countries (HICs). Objectives: The main aims were to compare the frequency of coagulopathy complications in developing countries (low- and middle-income countries [LMICs]) with those in HICs, delineate the frequency across a range of treatment levels, and determine associations with in-hospital mortality. Methods: Adult patients enrolled in an observational, multinational registry, the International Severe Acute Respiratory and Emerging Infections COVID-19 study, between January 1, 2020, and September 15, 2021, met inclusion criteria, including admission to a hospital for laboratory-confirmed, acute COVID-19 and data on complications and survival. The advanced-treatment cohort received care, such as admission to the intensive care unit, mechanical ventilation, or inotropes or vasopressors; the basic-treatment cohort did not receive any of these interventions. Results: The study population included 495,682 patients from 52 countries, with 63% from LMICs and 85% in the basic treatment cohort. The frequency of coagulopathy complications was higher in HICs (0.76%-3.4%) than in LMICs (0.09%-1.22%). Complications were more frequent in the advanced-treatment cohort than in the basic-treatment cohort. Coagulopathy complications were associated with increased in-hospital mortality (odds ratio, 1.58; 95% CI, 1.52-1.64). The increased mortality associated with these complications was higher in LMICs (58.5%) than in HICs (35.4%). After controlling for coagulopathy complications, treatment intensity, and multiple other factors, the mortality was higher among patients in LMICs than among patients in HICs (odds ratio, 1.45; 95% CI, 1.39-1.51). Conclusion: In a large, international registry of patients hospitalized for COVID-19, coagulopathy complications were more frequent in HICs than in LMICs (developing countries). Increased mortality associated with coagulopathy complications was of a greater magnitude among patients in LMICs. Additional research is needed regarding timely diagnosis of and intervention for coagulation derangements associated with COVID-19, particularly for limited-resource settings
Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19
- Author
- A M Udara Lakshan Attanyake
- Aasiyah Rashan
- Aasmine Kaur
- Abby Hurd
- Abdulrahman Al-Fares
- Abhijit Duggal
- Abid Khatak
- Adam Ali
- Adam Hall
- Adam Nowinski
- Adrian Ceccato
- Adrian Streinu-Cercel
- Adrian Tey
- Adrien Auvet
- Adrien Lemaignen
- Adrienne Chan
- Aftab Imtiaz
- Agamemnon Bakakos
- Agnieszka Oldakowska
- Agnès Meybeck
- Agnès Sommet
- Agostinho Monteiro
- Ahmad Afiq Ramli
- Ahmad Kashfi Haji Ab Rahman
- Ahmed Farooq
- Ailbhe Cullen
- Ailbhe Hayes
- Aine McCarthy
- Aine McElroy
- Aisha Kalsoom Mufti
- Aisling Gavin
- Aisling Murphy
- Aisling Murphy
- Akram Zaaqoq
- Al-Awwab Dabaliz
- Alan Hartman
- Alasdair Nazerali-Maitland
- Albert Groenendijk
- Alberto Sotto
- Alberto Uribe
- Alberto Zanella
- Albertus Beishuizen
- Aldo Rafael
- Aldric Manuel
- Alejandro Martin-Quiros
- Aleksander Rygh Holten
- Aleksandr Beljantsev
- Alessandra Notari
- Alex Browne
- Alex Nagrebetsky
- Alexa Debard
- Alexander Daniel Cornet
- Alexander J Mentzer
- Alexander King
- Alexander Zoufaly
- Alexandra Bedossa
- Alexandra Coelho
- Alexandra Sperry
- Alexandre Ducancelle
- Alexandre Gaymard
- Alexandre Hoctin
- Alexandros Cavayas
- Ali Ait Hssain
- Ali Hachemi
- Ali Liaquat
- Ali Raza
- Alice Bogaarts
- Alicia Gonzalez
- Alif Adlan Mohd Thabit
- Alina Kalicinska
- Alison M Meynert
- Allegra Chatterjee
- Allison McGeer
- Alpha Diallo
- Alphonsine Diouf
- Amanda Corley
- Amanda Palacios
- Amandine Gagneux-Brunon
- Amar Bhatt
- Ami Stuart
- Amin Khawaja
- Amina Meziane
- Amirul Asyraf
- Amna Faheem
- Amy Hackmann
- Amy Lester-Grant
- Amy Stone
- Amélie Valran
- Ana Catarino
- Ana Chora Sousa
- Ana da Silva Filipe
- Ana Freitas Ribeiro
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- Naseem Ali Shah
- Nasir Khoso
- Nassima Si Mohammed
- Natalie Mc Evoy
- Natalie Wright
- Nathalie Allou
- Nathalie DeCastro
- Nathalie Dournon
- Nathalie Gault
- Nathalie M Delfos
- Nathalie Pansu
- Nathan Peiffer-Smadja
- Naveed Latif
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- Navya Garimella
- Nawal Salahuddin
- Nazreen Abu Bakar
- Neerusha Kaisbain
- Nekliudov Nikita A
- Nelson Cardoso
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- Ng Yong Muh
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- Niamh Feely
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- Niamh Ni Leathlobhair
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- Nicholas Rizer
- Nicholas Sedillot
- Nicholas Yee Liang Hing
- Nicholas Yuri Barbosa
- Nick Daneman
- Nicky Van Der Vekens
- Nicolas Benech
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- Nicolas Carlier
- Nicolas Ferriere
- Nicolas Terzi
- Nicole White
- Nidyanara Castanheira
- Nik Nur Eliza Mohamed
- Nilar Lwin
- Nina Buchtele
- Nina Jamieson
- Nisreen Shiban
- Nobuaki Shime
- Nobuya Kitamura
- Noor Hidayu Wahab
- Nor Arisah Misnan
- Nor Zaila Binti Zaidan
- Nora Fuentes
- Noémie Mercier
- Noémie Tissot
- Noémie Vanel
- Nuno Germano
- Nuno Martins
- Nur Amira
- Nurnaningsih Nurnaningsih
- Nurul Amani Mohd Noordin
- Nurul Faten Izzati Norharizam
- Nurul Hidayah Mohammad Roslan
- Nurul Najmee Abdulkadir
- Nurul Zaynah
- Obada Yousif
- Odile Launay
- Ogechukwu Menkiti
- Oksana Kruglova
- Olavi Maasikas
- Oleksa Rewa
- Olga Martynenko
- Olguta Lungu
- Olivier Bouchaud
- Olivier Epaulard
- Olivier Lairez
- Olivier Lesens
- Olivier Picone
- Olivier Robineau
- Olivier Sanchez
- Olivier Terrier
- Olliaro Piero L
- Omar Mehkri
- Ong Yiaw Joe
- Ong David
- Oriane Puéchal
- Orna Ni Choileain
- Oryane Mabiala
- Osama Khalid
- Osama Metwally
- Oscar Hoiting
- Ouifiya Kafif
- P G Ishara Udayanga
- Pablo Blanco-Schweizer
- Pablo Serrano Balazote
- Paddy Mallon
- Pamela Combs
- Panda Prasan Kumar
- Paola Rodari
- Paolo Cattaneo
- Paolo Pelosi
- Parthena Savvidou
- Pascal Granier
- Pathik Dhanger
- Patricia Fontela
- Patricia Gordon
- Patricia Lizotte
- Patricia Patricio
- Patrick Archambault
- Patrick Biston
- Patrick Breen
- Patrick Breen
- Patrick Imbert
- Patrick Rispal
- Patrick Rossignol
- Paul Campbell
- Paul Dunand
- Paul Henri Wicky
- Paul Kambiya
- Paul Klenerman
- Paul Le Turnier
- Paul Loubet
- Paul McNally
- Paul Tierney
- Paul van der Valk
- Paula Custodio
- Pauline Caraux-Paz
- Pauline Yeung Ng
- Pawel Twardowski
- Pedrera Jiménez Miguel
- Pedro Faria
- Pedro Povoa
- Perren J Cobb
- Peter de Vries
- Peter Doran
- Peter Kiiza
- Peter Openshaw
- Peter S Timashev
- Peter Van der Voort
- Petr Glybochko
- Petrovic Michele
- Phil Gallagher
- Philippe Jouvet
- Philippine Eloy
- Phoebe Ampaw
- Piero Valentini
- Pierre Delobel
- Pierre Jaquet
- Pierre Tattevin
- Pierre-Adrien Bolze
- Pierre-François Sandrine
- Pierre-Marc Villeneuve
- Pierre-Marie Roger
- Pieter Depuydt
- Piret Sillaots
- Pleun Terpstra
- Polina Bugaeva
- Pompini Agustina Sitompul
- Pooja Varghese
- Pramesh Sundar Shrestha
- Pranya Sakiyalak
- Pratap Karpayah
- Pratheema Ramachandran
- Praveen Kumar Ghisulal
- Priscila Diaz
- Pritchard Mark G
- Prompak Nitayavardhana
- Pulak Kedia
- Punam Singh
- Qabas Alkhafajee
- Quentin Le Hingrat
- Quentin Lepiller
- Quratul Ain Khan
- Rachael McConnochie
- Rachael Parke
- Rachel Cregan
- Rachida Ouissa
- Rafael Freitas de Oliveira França
- Rafael León
- Rafael Mahieu
- Rajavardhan Rangappa
- Rajesh Mohan Shetty
- Rajyabardhan Pattnaik
- Rakesh Arora
- Ramakrishnan Nagarajan
- Ramos Grazielle Viana
- Rana Imran Sikander
- Raph L Hamers
- Raphaël Borie
- Raphaël Favory
- Raquel Pinto
- Rashan Haniffa
- Rashid Nasim Khan
- Rasidah Bt Senian
- Raul Neto
- Razi Alalqam
- Rebecca Hamidfar
- Rebecca Holt
- Rebekha Garcia
- Renata Barbalho
- Renato Reis
- Renaud Tamisier
- Renee Douma
- Ricard Ferrer-Roca
- Ricardo Fritz
- Richard S Tedder
- Riinu Pius
- Rima Song
- Rita Alves
- Rita Hinchion
- Ritika Ranjan
- Rob Klont
- Robert A Fowler
- Roberta Cavalin
- Roberta Meta
- Roberto Andini
- Roberto Roncon-Albuquerque
- Robin Kobbe
- Rodrigo Diaz
- Roger Claire
- Rogério Silva
- Rohan Shetty
- Rojek Amanda
- Rolando Claure-Del Granado
- Romain Basmaci
- Romain Decours
- Romain Guery
- Roman Ullrich
- Romans Matulevics
- Rosanna De Rosa
- Rosario Maria Torres Santos-Olmo
- Ross Hendry
- Rostane Gaci
- Roxane Courtois
- Rozanah Abd Rahman
- Rui Gomes
- Rui Pereira
- Rumaisah Satyawati
- Rupert Higgins
- Ruth Jimbo-Sotomayor
- Ruth Lyons
- Ruth N Jorge García
- Ryadh Pokeerbux
- Ryan Kennedy
- Ryan Khoo
- Ryan S Thwaites
- Ryuzo Abe
- Saad Nseir
- Sabelline Bouchez
- Sabin Koirala
- Sabina Kali
- Sabina Mason
- Sabine Cornelis
- Sabine Croonen
- Sadie Kelly
- Saef Umar Barnett
- Saijad Orakzai
- Sairah Sadaf
- Sakshi Lath
- Saleh Al Ageel
- Sally Shrapnel
- Salma Jaafoura
- Samira Laribi
- Samreen Ijaz
- Samuel Bernard Ekow Harrison
- Samuel Hinton
- Samuel Markowicz
- Samuel McElwee
- Sandrine Couffin-Cadiergues
- Sandulescu Oana
- Sanjay Lakhey
- Sanne Wesselius
- Santi Dewayanti
- Saptadi Yuliarto
- Sara Clohisey
- Sara Taleb
- Sara Ventura
- Sarah E McDonald
- Sarah Isgett
- Sarah Moore
- Sarah Redl
- Sarah Stabler
- Sarah Syahrin
- Sarah Tubiana
- Saye Khoo
- Scott Pharand
- Seamus Daly
- Sean Donohue
- Sebastian Vencken
- Sebastiano Maria Colombo
- Segolène Greffe
- Semple Malcolm G
- Senthilkumar Alegesan
- Sergio Poli
- Seán Keating
- Shahdattul Mawarni Taib
- Shaikh Sharjeel
- Shakeel Ahmed
- Shaminee Veeran
- Sharma Keshav
- Sharma Pratima
- Shaun Thompson
- Shaunagh Browne
- Sheeba Hakak
- Sheila Cárcel
- Sherry McDermott
- Sheryl Ann Abdukahil
- Shinichiro Ohshimo
- Shiranee Sriskandan
- Shirin Tabrizi
- Shirley Sarfo-Mensah
- Shoban Raj Vasudayan
- Shona C Moore
- Shubha Kalyan Shrestha
- Sia Loong Tonnii
- Sigfrid Louise
- Silvia Castañeda
- Silvia Lourenco
- Sim Choon Ean
- Sim Lim Heng Benedict
- Simon Bessis
- Simon Forsyth
- Simon-Djamel Thiberville
- Simone Carelli
- Simão Rodeia
- Singh Oinam Budha Charan
- Siobhan Casey
- Siobhan Egan
- Siri Goepel
- Siti Nurul Atikah Ahmad Ridzuan
- Siti Rohani Binti Mohd Yakop
- Siti Zubaidah Othman
- Sivanesen Anthonidass
- Smaragdi Kalomoiri
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- Sofia Cardoso
- Sofia Prapa
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- Sophie Mahy
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- Sree Satyapriya
- Srinivas Murthy
- Stanislas Rebaudet
- Steffi Ryckaert
- Stella Huo
- Stella Rousset
- Stephan Schroll
- Stephanie Nonas
- Stephanie Roberts
- Stephanie Yerkovich
- Stephanie-Susanne Stecher
- Stephen R Knight
- Steve Webb
- Stijn Van de Velde
- Streinu-Cercel Anca
- Stuart Houltham
- Stéphane Jaureguiberry
- Stéphane Lasry
- Stéphane Sallaberry
- Stéphanie Cousse
- Stéphanie Fry
- Su Hwan Lee
- Subbarao Elapavaluru
- Subhash Acharya
- Sudhir Krishnan
- Sue Smith
- Suhaila Abdul Wahab
- Sung-Min Cho
- Surain Raaj Thanga Thurai
- Suresh Kumar Chidambaram
- Surya Otto Wijaya
- Susana Cabral
- Susana Fernandes
- Susanne Dudman
- Sushil Khanal
- Suvintheran Thangavelu
- Suwarti Suwarti
- Suzanne Bennett
- Suzette Willems
- Swosti Joshi
- Syamin Asyraf Shahidan
- Sybille Bevilcaqua
- Syed Muneeb
- Sylvain Diamantis
- Sylvie Behilill
- Sylvie LeGac
- Sylvie Lion-Daolio
- Sylvie Van Der Werf
- Synne Jenum
- Sze Kye Teoh
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- Sérgio Gaião
- Séverine Ansart
- Sílvia Ferreira
- T Eoin West
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- Tae Song
- Taha Pasha
- Tahira Jamal Mohamed
- Tak-Hyuk Oh
- Takako Akimoto
- Takayuki Ogura
- Taku Tanaka
- Tala Al-Dabbous
- Tamara Seitz
- Tan Pei Wen
- Tarek Elshazly
- Tatiana Fonseca
- Tawnya Ogston
- Teck Fung Wong
- Teresa Lawrence
- Terese Hammond
- Thalha Rashan
- Tharmini Ravi
- Tharwat Aisa
- Thavamany Kaleesvran
- Thibault Chiarabini
- Thierry Carmoi
- Thierry Mazzoni
- Thomas Flament
- Thomas Guimard
- Thomas Maitre
- Thomas Perpoint
- Thomas Staudinger
- Thushan de Silva
- Théo Treoux
- Tiago Isidoro
- Tiago Reyes
- Tiffany Trouillon
- Timo Brandenburger
- Timothy M Uyeki
- Ting Soo Chow
- Tiphaine Goulenok
- Tjard Schermer
- Todd C Lee
- Todd Karsies
- Tom Drake
- Tom Fletcher
- Tom Solomon
- Tomoyuki Endo
- Toni Duculan
- Tony Trapani
- Toshiki Yokoyama
- Triona Downer
- Tristan Gigante
- Trude Steinsvik
- Tze Vee Soh
- Tze Yuan Tee
- Tânia Sequeira
- Vadim Tieroshyn
- Valentine Campana
- Valeria Balan
- Valla Sahraei
- Valérie Gaborieau
- Valérie Garrait
- Valérie Gissot
- Vanessa Sancho-Shimizu
- Vanessa Teotonio
- Vanina Meysonnier
- Vecham Pavan Kumar
- Vegard Skogen
- Ventzislava Petrov-Sanchez
- Vicente Souza-Dantas
- Victor Fomin
- Victoria Janes
- Victoria Manda
- Victoria McEneany
- Victoria Shaw
- Vilmaris Quinones-Cardona
- Vincent Dinot
- Vincent Dubee
- Vincent Enouf
- Vincent Langlois
- Vincent Le Moing
- Vincent Peigne
- Vincent Pestre
- Vincent Thibault
- Vinothini Krishnan
- Virginie Williams
- Vladislav Mihnovit
- Véronique Lemee
- Víctor Quirós González
- Wai Ching Sin
- Walter Picard
- Wan Fadzlina Wan Muhd Shukeri
- Wei Han Hoh
- Wei Shen Lim
- Wei Jia
- Wendy S Barclay
- William A Paxton
- William Dechert
- William Finlayson
- William Greenhalf
- Wilna Oosthuyzen
- Wils Evert-Jan
- Wim Dieperink
- Wing Yiu Ng
- Xavier Duval
- Yael Dishon
- Yan Chyi Tan
- Yaseen Arabi
- Yasmin Gani
- Yazdan Yazdanpanah
- Yen Tsen Saw
- Yew Sing Wong
- Yi Bin Ho
- Yi Lin Lee
- Yih-Sharng Chen
- Ymkje Stienstra
- Yoan Lavie-Badie
- Yoann Donohue
- Yock Ping Chow
- Younes Ait Tamlihat
- Younes Kerroumi
- Yun Sii Ing
- Yuri Kida
- Yusing Gu
- Yvelynne Kelly
- Yves Levy
- Zhang Duan Tham
- Zul Amali Che Kamaruddin
- Zul Fakar
- Zulfiqar Sandhu
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 28/02/2023
- Field of study
Background: We describe demographic features, treatments and clinical outcomes in the International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) COVID-19 cohort, one of the world's largest international, standardized data sets concerning hospitalized patients. Methods: The data set analysed includes COVID-19 patients hospitalized between January 2020 and January 2022 in 52 countries. We investigated how symptoms on admission, co-morbidities, risk factors and treatments varied by age, sex and other characteristics. We used Cox regression models to investigate associations between demographics, symptoms, co-morbidities and other factors with risk of death, admission to an intensive care unit (ICU) and invasive mechanical ventilation (IMV). Results: Data were available for 689 572 patients with laboratory-confirmed (91.1%) or clinically diagnosed (8.9%) SARS-CoV-2 infection from 52 countries. Age [adjusted hazard ratio per 10 years 1.49 (95% CI 1.48, 1.49)] and male sex [1.23 (1.21, 1.24)] were associated with a higher risk of death. Rates of admission to an ICU and use of IMV increased with age up to age 60 years then dropped. Symptoms, co-morbidities and treatments varied by age and had varied associations with clinical outcomes. The case-fatality ratio varied by country partly due to differences in the clinical characteristics of recruited patients and was on average 21.5%. Conclusions: Age was the strongest determinant of risk of death, with a ∼30-fold difference between the oldest and youngest groups; each of the co-morbidities included was associated with up to an almost 2-fold increase in risk. Smoking and obesity were also associated with a higher risk of death. The size of our international database and the standardized data collection method make this study a comprehensive international description of COVID-19 clinical features. Our findings may inform strategies that involve prioritization of patients hospitalized with COVID-19 who have a higher risk of death