2,593 research outputs found
A quasi classical approach to fully differential ionization cross sections
A classical approximation to time dependent quantum mechanical scattering in
the M\o{}ller formalism is presented. Numerically, our approach is similar to a
standard Classical-Trajectory-Monte-Carlo calculation. Conceptually, however,
our formulation allows one to release the restriction to stationary initial
distributions. This is achieved by a classical forward-backward propagation
technique. As a first application and for comparison with experiment we present
fully differential cross sections for electron impact ionization of atomic
hydrogen in the Erhardt geometry.Comment: 6 pages, 2 figure
AMPK Regulation of Mouse Oocyte Meiotic Resumption in Vitro
We have previously shown that the adenosine analog 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR), an activator of AMP-activated protein kinase (AMPK), stimulates an increase in AMPK activity and induces meiotic resumption in mouse oocytes [Downs, S.M., Hudson, E.R., Hardie, D.G., 2002. A potential role for AMP-activated protein kinase in meiotic induction in mouse oocytes. Dev. Biol, 245, 200–212]. The present study was carried out to better define a causative role for AMPK in oocyte meiotic maturation. When microinjected with a constitutively active AMPK, about 20% of mouse oocytes maintained in meiotic arrest with dibutyryl cAMP (dbcAMP) were stimulated to undergo germinal vesicle breakdown (GVB), while there was no effect of catalytically dead kinase. Western blot analysis revealed that germinal vesicle (GV)-stage oocytes cultured in dbcAMP-containing medium plus AICAR possessed elevated levels of active AMPK, and this was confirmed by AMPK assays using a peptide substrate of AMPK to directly measure AMPK activity. AICAR-induced meiotic resumption and AMPK activation were blocked by compound C or adenine 9-beta-d-arabinofuranoside (araA, a precursor of araATP), both inhibitors of AMPK. Compound C failed to suppress adenosine uptake and phosphorylation, indicating that it did not block AICAR action by preventing its metabolism to the AMP analog, ZMP. 2′-Deoxycoformycin (DCF), a potent adenosine deaminase inhibitor, reversed the inhibitory effect of adenosine on oocyte maturation by modulating intracellular AMP levels and activating AMPK. Rosiglitazone, an anti-diabetic agent, stimulated AMPK activation in oocytes and triggered meiotic resumption. In spontaneously maturing oocytes, GVB was preceded by AMPK activation and blocked by compound C. Collectively, these results support the proposition that active AMPK within mouse oocytes provides a potent meiosis-inducing signal in vitro
Exploring the equivalence of two common mixture models for duration data
The beta-geometric (BG) distribution and the Pareto distribution of the second kind (P(II)) are two basic models for duration-time data that share some underlying characteristics (i.e., continuous mixtures of memoryless distributions), but differ in two important respects: first, the BG is the natural model to use when the event of interest occurs in discrete time, while the P(II) is the right choice for a continuous-time setting. Second, the underlying mixing distributions (the beta and gamma for the BG and P(II), respectively, are very different—and often believed to be non-comparable with each other. Despite these and other key differences, the two models are strikingly similar in terms of their fit and predictive performance as well as their parameter estimates. We explore this equivalence, both empirically and analytically, and discuss the implications from both a substantive and methodological standpoint
A semi-classical over-barrier model for charge exchange between highly charged ions and one-optical electron atoms
Absolute total cross sections for electron capture between slow, highly
charged ions and alkali targets have been recently measured. It is found that
these cross sections follow a scaling law with the projectile charge which is
different from the one previously proposed basing on a classical over-barrier
model (OBM) and verified using rare gases and molecules as targets. In this
paper we develop a "semi-classical" (i.e. including some quantal features) OBM
attempting to recover experimental results. The method is then applied to
ion-hydrogen collisions and compared with the result of a sophisticated
quantum-mechanical calculation. In the former case the accordance is very good,
while in the latter one no so satisfactory results are found. A qualitative
explanation for the discrepancies is attempted.Comment: RevTeX, uses epsf; 6 pages text + 3 EPS figures Journal of Physics B
(scehduled March 2000). This revision corrects fig.
The use of hand-held computers (PDAs) to audit and validate eradication of a post-border detection of Khapra Beetle, Trogoderma granarium, in Western Australia
Most of Australia’s agricultural produce is exported. Demonstrating freedom from certain plant and animal pests and diseases is critical to securing and maintaining market access. Surveillance is an important tool in gaining market access and accordingly exporting countries now need to provide accurate, credible evidence to confirm pest freedom status.In the past nearly all field-collected surveillance information was recorded manually to paper reducing the rate of capture, integrity, conformity as well as security of the data. This paper describes the development of pest surveillance data collection software and hardware using PDAs (Personal Digital Assistants) to provide auditing, validation, chain of evidence and increase the volume of data collected as well as its integrity through relational databases and seamless data transfer to corporate systems. The system’s first deployment was during a T. granarium eradication. The khapra beetle (Trogoderma granarium) is one of the most serious pests of stored grain and is a regulated quarantine pest in most countries around the world. In April 2007, there was a post-border detection of T. granarium larvae and adults in a Western Australian residence. Immediate and uncompromising action was taken to quarantine the home and fumigate it with methyl-bromide at an internationally established rate known to control T. granarium (AQIS T9056). A two-year T. granarium trapping program was undertaken which used PDA software to provide evidence of complete eradication via 1273 trap inspections. This achievement was supported by GPSlocated traps, digital voice navigation itineraries, digital time and date stamps, field printed barcode labels, site imagery, all in a single hand-held unit. Keywords: T. granarium, Khapra beetle, Eradication, Biosecurity, PDA, Surveillanc
A hybrid MLP-PNN architecture for fast image superresolution
Proceedings of Joint International Conference ICANN/ICONIP 2003 Istanbul, Turkey, June 26–29, 2003The final publication is available at Springer via http://dx.doi.org/10.1007/3-540-44989-2_50Image superresolution methods process an input image sequence of a scene to obtain a still image with increased resolution. Classical approaches to this problem involve complex iterative minimization procedures, typically with high computational costs. In this paper is proposed a novel algorithm for superresolution that enables a substantial decrease in computer load. First, a probabilistic neural network architecture is used to perform a scattered-point interpolation of the image sequence data. The network kernel function is optimally determined for this problem by a multi-layer perceptron trained on synthetic data. Network parameters dependence on sequence noise level is quantitatively analyzed. This super-sampled image is spatially filtered to correct finite pixel size effects, to yield the final high-resolution estimate. Results on a real outdoor sequence are presented, showing the quality of the proposed method.This work has been partially supported by TIC2001-0572-C02-02 gran
Reference Distorted Prices
I show that when consumers (mis)perceive prices relative to reference prices,
budgets turn out to be soft, prices tend to be lower and the average quality of
goods sold decreases. These observations provide explanations for decentralized
purchase decisions, for people being happy with a purchase even when they have
paid their evaluation, and for why trade might affect high quality local firms
'unfairly'
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