3-Chloro-6-[4-(2-pyrid­yl)piperazin-1-yl]pyridazine

In the title compound, C13H14ClN5, the piperazine ring adopts a chair conformation and the dihedral angle between the aromatic rings is 13.91 (7)°. The crystal structure is stabilized by weak inter­molecular C—H⋯N hydrogen-bond inter­actions

Fallstudien: kritische einschatzung

Das Ziel dieses Artikels ist es, das Wesentliche bei der Fallstudie festzustellen und eine kritische Einschatzung dieser Methode durchzufuhren. Infolgedessen wird zunachst der Versuch gemacht, den Begriff des Falls und der Fallstudie darzustellen. Anschlie?end werden die Vor- und Nachteile, d.h. die Moglichkeiten und die Grenzen der Fallstudie diskutiert und entsprechende Folgerungen gemacht.Статья посвящена проблеме определения "кейса" и "метода кейсов", а также возможностям применения и недостаткам данного метода

Reactions of Rhenium and Manganese Carbonyl Complexes with 1,8-bis(diphenylphosphino)naphthalene: Ligand Chelation, C–H and C–P bond-cleavage Reactions

Reaction of [Re2(CO)8(MeCN)2] with 1,8-bis(diphenylphosphino)naphthalene (dppn) afforded three mono-rhenium complexes fac-[Re(CO)3(κ1:η1-PPh2C10H6)(PPh2H)] (1), fac-[Re(CO)3{κ1:κ1:η1-(O)PPh2C10H6(O)PPh(C6H4)}] (2) and fac-[ReCl(CO)3(κ2-PPh2C10H6PPh2)] (3). Compounds 1–3 are formed by Re–Re bond cleavage and P–C and C–H bond activation of the dppn ligand. Each of these three complexes have three CO groups arranged in facial fashion. Compound 1 contains a chelating cyclometalated diphenylnaphthylphosphine ligand and a terminally coordinated PPh2H ligand. Compound 2 consists of an orthometalated dppn-dioxide ligand coordinated in a κ1:κ1:η1-fashion via both the oxygen atoms and ortho-carbon atom of one of the phenyl rings. Compound 3 consists of an unchanged chelating dppn ligand and a terminal Cl ligand. Treatment of [Mn2(CO)8(MeCN)2] with a slight excess of dppn in refluxing toluene at 72 °C, gave the previously reported [Mn2(CO)8(μ-PPh2)2] (4), formed by cleavage of C–P bonds, and the new compound fac-[MnCl(CO)3(κ2-PPh2C10H6PPh2)] (5), which has an unaltered chelating dppn and a terminal Cl ligand. In sharp contrast, reaction of [Mn2(CO)8(MeCN)2] with slight excess of dppn at room temperature yielded the dimanganese [Mn2(CO)9{κ1-PPh2(C10H7)}] (6) in which the diphenylnaphthylphosphine ligand, formed by facile cleavage of one of the P–C bonds, is axially coordinated to one Mn atom. Compound 6 was also obtained from the reaction of [Mn2(CO)9(MeCN)] with dppn at room temperature. The XRD structures of complexes 1–3, 5, 6 are reported

Spectroscopy and Electrochemistry of Cobalt(III) Schiff Base Complexes

The structural, spectroscopic, and electrochemical properties of cobalt(III) derivatives of acacen (H_2acacen = bis(acetylacetone) ethylenediimine) and related ligands have been investigated. Electronic structure calculations indicate that the absorption between 340 and 378 nm in Co^(III)(acacen) spectra is attributable to the lowest π−π* intraligand charge-transfer transition. Equatorial ligand substitutions affect reduction potentials less than axial ligand changes, consistent with an electronic structural model in which d_(z^2) is populated in forming cobalt(II). The crystal structure of [Co(3-Cl-acacen)(NH_3)_2]BPh_4 has been determined:  The compound crystallizes in the monoclinic space group (P2_1)/m (No. 11) with a = 9.720(2) Å, b = 18.142(4) Å, c = 10.046(2) Å, β = 100.11(3)°, D_c = 1.339 g cm^(-3), and Z = 2; the complex cation, [Co(3-Cl-acacen)(NH_3)_2]^+, exhibits a slightly distorted octahedral coordination geometry. The distances between the cobalt atom and the two axial nitrogen donor atoms differ only slightly (1.960(6) and 1.951(6) Å) and are similar to Co−N distances found in cobalt−ammine complexes as well as the axial Co−N distances in [Co(acacen)(4-MeIm)_2]Br·1.5H_2O; the latter compound crystallizes in the triclinic space group P1̄ (No. 2) with a = 18.466(9) Å, b = 14.936(7) Å, c = 10.111(5)Å, α = 96.27(5)°, β = 94.12(5)°, γ = 112.78(5)°, D_c = 1.447 g cm^(-3), and Z = 4

(S)-2-Amino-2-(2-chloro­phen­yl)cyclo­hexa­none

The crystal structure of the title compound, C12H14ClNO, was determined in order to confirm that the chiral center of the mol­ecule has an S configuration. The cyclo­hexa­none ring adopts a chair conformation. The 2-chloro­phenyl ring is slightly twisted from the axial C—N bond, with a N—C—C—C torsion angle of −5.7 (2)°. In the crystal, an inter­molecular N—H⋯O hydrogen bond links adjacent mol­ecules into an infinite chain, which propagates in the b-axis direction

2-(4-Meth­oxy-2-methyl­anilino)-1,2-diphenyl­ethanone

The title compound, C22H21NO2, was synthesized from 4-meth­oxy-2-methyl­aniline and 2-hy­droxy-1,2-diphenyl­ethanone. In the title compound, the C—C—C—N—C backbone adopts an all-trans conformation. The crystal structure is stabilized by weak inter­molecular C—H⋯O hydrogen-bond inter­actions

Radio source-component association for the LOFAR Two-metre Sky Survey with region-based convolutional neural networks

Large scale structure and cosmolog

3-Chloro-6-{4-[3-(trifluoro­meth­yl)phen­yl]piperazin-1-yl}pyridazine

The title compound, C15H14ClF3N4, was synthesized from 3,6-dichloro­pyridazine and 1-[3-(trifluoro­meth­yl)phen­yl]piper­azine. The piperazine ring is flanked by 3-chloro­pyridazine and 3-trifluoro­methyl­phenyl rings and adopts a chair conformation, whereas the 3-chloro­pyridazine and 3-trifluoro­methyl­phenyl rings are planar, with maximum deviations of 0.0069 (13) and 0.0133 (14) Å, respectively. The crystal structure is stabilized by weak inter­molecular C—H⋯N hydrogen-bond inter­actions

Innovative customer loyalty programs

Currently, the vast majority of demanding consumers has tired of monotonous bonuses and benefits companies. Today innovations play an important role in all areas of our lives. And marketing is not an exception. So, the marketers make innovative and personalized solutions to create loyal customers. In this connection, in the present conditions the development of innovative customer loyalty program is one of the priorities of any company.Инновации в различных сферах деятельности играют важную роль. В настоящее время преобладающее большинство требовательных и взыскательных потребителей уже перенасыщено однообразными бонусами и льготами компаний. Поэтому производители акцентируют внимание на инновационных и персонализированных решениях формирования контингента приверженных клиентов компании. В связи с этим в современных условиях разработка инновационной программы лояльности клиентов является одним из приоритетных направлений развития любого предприятия