925 research outputs found

    Multiple-relaxation-time lattice Boltzmann simulation of natural convection flow in a partitioned cavity using GPU computing

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    © 2019 Author(s). In this paper, we demonstrated the implementation of General Purpose Graphics Processing Unit (GPGPU) programming in Compute Unified Device Architecture (CUDA) C for the simulation of natural convection flow in a side-heated three-dimensional (3D) rectangular cavity with a partition. In the present lattice Boltzmann method (LBM) D3Q19 multiple-relaxation-time (MRT) and D3Q6 single relaxation-time (SRT) model are implemented for the simulation of fluid flow and temperature phenomena, respectively. The parallel code is validated with the benchmark problem of a side heated cubic cavity. The results are presented by the temperature distribution in terms of isotherms, local and average Nusselt number and 3D view of iso-surface for the different Rayleigh number (Ra) and the Prandtl number fixed at Pr = 0.71. It is also observed that the present parallel implementation of the MRT-lattice Boltzmann simulation in GPU has a substantial computational effciency rather than the sequential programming in central processing units (CPU)

    Effect of dietary supplementation of turmeric (Curcuma Longa), ginger (Zingiber Officinale) and their combination as feed additives on feed intake, growth performance and economics of broiler

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    Objective: The present study was carried out to assess the consequence of supplementation of turmeric, ginger and their combination in the diets of broiler chickens and assessment in terms of feed intake, growth performance and economics of feeding. Materials and Methods: A total of 360 day old Cobb-500 chicks were randomly allocated to six dietary treatments each with three replicates of 20 chicks/replicate (n = 60). Six experimental diets were formulated in such a way that control diet (T0) contained neither turmeric nor ginger. Birds in group T1and T2were fed diets containing 0.50 and 0.75% turmeric, whereas birds in group T3and T4fed diet contained 0.50 and 0.75% ginger, respectively. Birds in group T5fed diets containing a combination of 0.50% ginger and 0.50% turmeric with commercial feed. The feeding experiment was carried out for 32 days and different parameters measured included: feed intake, weight gain, feed conversion ratio, dressing percentage and blood parameters. Results: Feed intake of experimental birds in T4group was higher compared to other groups, i.e., (T0, T1, T2, T3and T5) without a significant level. A body weight gain (g/bird) was found to be significantly (p<0.05) higher in ginger (T3group) and turmeric (T2group) supplemented group as compare to T4, T1, T5and T0group. Feed Conversion Ratio (FCR) was significantly (p<0.05) lower in the T3group as compare to other groups. The dressing percentage, thigh weight, back, neck, wing percentages and blood parameters (Hb, PCV and ESR) were not statistically different among control and other treatment groups. However, the relative weight of breast, wing, gizzard and proventriculus were significantly increased (p<0.05). The cost of production and return of birds was highly economical in treatment T2as compared to other treatment groups. Conclusion: On the basis of the results of the study, it is concluded that supplementation of turmeric (Curcuma longa) improves the growth performance of broilers when added at the rate of 0.75% level as feed additives in broiler ration

    Pertobatan Akademis

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    The biggest difficulty of humans cannot change or advance the quality of life is an unwillingness to change their errors and shortcomings and to repent from it. There is also willing to change but they do not change just because no action and do not really do it. There are also people who have already known that it is true, accurate, should be performed and corresponding to the norms, but still they live in sin and self-interest to ignore the interests of others. Even worse is evil (sin) is often covered in hypocrisy behind beautiful, sweet, gentle, and courteous words to make people mesmerized/hypnotized. In the case of real repentance, it should demand a match between words and actions. If there is repentance, there is a change and peace. Therefore, humans must sincerely repent and strive for it

    Mapping the disease-specific LupusQoL to the SF-6D

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    Purpose To derive a mapping algorithm to predict SF-6D utility scores from the non-preference-based LupusQoL and test the performance of the developed algorithm on a separate independent validation data set. Method LupusQoL and SF-6D data were collected from 320 patients with systemic lupus erythematosus (SLE) attending routine rheumatology outpatient appointments at seven centres in the UK. Ordinary least squares (OLS) regression was used to estimate models of increasing complexity in order to predict individuals’ SF-6D utility scores from their responses to the LupusQoL questionnaire. Model performance was judged on predictive ability through the size and pattern of prediction errors generated. The performance of the selected model was externally validated on an independent data set containing 113 female SLE patients who had again completed both the LupusQoL and SF-36 questionnaires. Results Four of the eight LupusQoL domains (physical health, pain, emotional health, and fatigue) were selected as dependent variables in the final model. Overall model fit was good, with R2 0.7219, MAE 0.0557, and RMSE 0.0706 when applied to the estimation data set, and R2 0.7431, MAE 0.0528, and RMSE 0.0663 when applied to the validation sample. Conclusion This study provides a method by which health state utility values can be estimated from patient responses to the non-preference-based LupusQoL, generalisable beyond the data set upon which it was estimated. Despite concerns over the use of OLS to develop mapping algorithms, we find this method to be suitable in this case due to the normality of the SF-6D data

    IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection

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    Funding: This work was funded by a Career Development Fellowship (1028634) and a project grant (GRNT1028641) awarded to AHa by the Australian National Health & Medical Research Council (NHMRC). IS was supported by The University of Queensland Centennial and IPRS Scholarships. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublisher PD

    Sugar Ka Saathi – A Case Study Designing Digital Self-management Tools for People Living with Diabetes in Pakistan

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    This paper presents the results of an iterative participatory process to design a smart self-management tool for less-literate people living with diabetes in Pakistan. Initially, interviews and focus groups with sixty-nine people living with diabetes identified issues that they face when self-managing including un-controllable factors, lack of diabetes awareness, low-tech mobile phones, and poor internet availability. We developed personas grounded in the scoping results and adjusted our PD approach to focus on more tangible design artefacts before running narrative scoping PD sessions. Working from older, illiterate persona, we designed a phone-line delivered Interactive Voice Response (IVR) system. We developed a functional IVR Prototype “Sugar ka Saathi” (Diabetes Companion) with input from a group of 4 Pakistan-based healthcare professionals, to act as a design probe in the PD process. We tested the IVR probe with fifty-seven of the original scoping participants which validated the knowledge transferred by the IVR and its acceptability. Invisible design videos were shown to elaborate the IVR and community concept to thirteen participants through two filmed videos using our existing persona characters from the scoping studies, these videos helped to engage older people with diabetes in PD sessions

    Genetic, environmental and stochastic factors in monozygotic twin discordance with a focus on epigenetic differences

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    PMCID: PMC3566971This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

    Tissue Invasion by Entamoeba histolytica: Evidence of Genetic Selection and/or DNA Reorganization Events in Organ Tropism

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    Entamoeba histolytica infection may have various clinical manifestations. Nine out of ten E. histolytica infections remain asymptomatic, while the remainder become invasive and cause disease. The most common form of invasive infection is amebic diarrhea and colitis, whereas the most common extra-intestinal disease is amebic liver abscess. The underlying reasons for the different outcomes are unclear, but a recent study has shown that the parasite genotype is a contributor. To investigate this link further we have examined the genotypes of E. histolytica in stool- and liver abscess-derived samples from the same patients. Analysis of all 18 paired samples (16 from Bangladesh, one from the United States of America, and one from Italy) revealed that the intestinal and liver abscess amebae are genetically distinct. The results suggest either that E. histolytica subpopulations in the same infection show varying organ tropism, or that a DNA reorganization event takes place prior to or during metastasis from intestine to liver
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