Analysis of single-unit responses to emotional scenes in human ventromedial prefrontal cortex

Lesion and functional imaging studies in humans have shown that the ventral and medial prefrontal cortex is critically involved in the processing of emotional stimuli, but both of these methods have limited spatiotemporal resolution. Conversely, neurophysiological studies of emotion in nonhuman primates typically rely on stimuli that do not require elaborate cognitive processing. To begin bridging this gap, we recorded from a total of 267 neurons in the left and right orbital and anterior cingulate cortices of four patients who had chronically implanted depth electrodes for monitoring epilepsy. Peristimulus activity was recorded to standardized, complex visual scenes depicting neutral, pleasant, or aversive content. Recording locations were verified with postoperative magnetic resonance imaging. Using a conservative, multistep statistical evaluation, we found significant responses in 56 neurons; 16 of these were selective for only one emotion class, most often aversive. The findings suggest sparse and widely distributed processing of emotional value in the prefrontal cortex, with a predominance of responses to aversive stimuli

The Archaeology of a Manuscript : Huntington Library HM 266

Hanna III Ralph. The Archaeology of a Manuscript : Huntington Library HM 266. In: Scriptorium, Tome 36 n°1, 1982. pp. 99-102

Monstrous Words, Monstrous Bodies: Irony and the Walking Dead in Walter Map's De Nugis Curialium

This article analyses the function of the tales of the walking dead found in Distinction II of Walter Map's De Nugis Curialium (c.1182). Map's sole surviving work, the “Courtiers’ Trifles” is a collection of historical narratives, wonder stories, witty asides and anecdotes collated during his employment at Henry II's court. The satirical nature of the De Nugis has been noted by previous scholars; however, this has yet to be discussed specifically with regard to the tales of the undead. Following a discussion of the twelfth-century traditions of satirical literature and the ways in which medieval authors approached the trope of irony, the second part of the narrative will examine how Map, a master of the “art of lying”, deconstructed the conventions of wonder stories. It will be argued that as well as using these tales to satirise the historiographical function of mirabilia, they were also used to critique the reality of court life and, on a deeper level, the literary function of ambiguity itself. The inherent irony of the walking dead, the dissonance between physical form and metaphysical intent, meant that they could be inscribed with multiple, parallel meanings

Jet fragmentation transverse momentum distributions in pp and p-Pb collisions at s \sqrt{s} , sNN \sqrt{s_{\mathrm{NN}}} = 5.02 TeV

Jet fragmentation transverse momentum (j$_{T}$) distributions are measured in proton-proton (pp) and proton-lead (p-Pb) collisions at $\sqrt{s_{\mathrm{NN}}}$ = 5.02 TeV with the ALICE experiment at the LHC. Jets are reconstructed with the ALICE tracking detectors and electromagnetic calorimeter using the anti-k$_{T}$ algorithm with resolution parameter R = 0.4 in the pseudorapidity range |η| < 0.25. The j$_{T}$ values are calculated for charged particles inside a fixed cone with a radius R = 0.4 around the reconstructed jet axis. The measured j$_{T}$ distributions are compared with a variety of parton-shower models. Herwig and Pythia 8 based models describe the data well for the higher j$_{T}$ region, while they underestimate the lower j$_{T}$ region. The j$_{T}$ distributions are further characterised by fitting them with a function composed of an inverse gamma function for higher j$_{T}$ values (called the “wide component”), related to the perturbative component of the fragmentation process, and with a Gaussian for lower j$_{T}$ values (called the “narrow component”), predominantly connected to the hadronisation process. The width of the Gaussian has only a weak dependence on jet transverse momentum, while that of the inverse gamma function increases with increasing jet transverse momentum. For the narrow component, the measured trends are successfully described by all models except for Herwig. For the wide component, Herwig and PYTHIA 8 based models slightly underestimate the data for the higher jet transverse momentum region. These measurements set constraints on models of jet fragmentation and hadronisation