7,179 research outputs found
Simulations of a Scintillator Compton Gamma Imager for Safety and Security
We are designing an all-scintillator Compton gamma imager for use in security
investigations and remediation actions involving radioactive threat material.
To satisfy requirements for a rugged and portable instrument, we have chosen
solid scintillator for the active volumes of both the scatter and absorber
detectors. Using the BEAMnrc/EGSnrc Monte Carlo simulation package, we have
constructed models using four different materials for the scatter detector:
LaBr_3, NaI, CaF_2 and PVT. We have compared the detector performances using
angular resolution, efficiency, and image resolution. We find that while PVT
provides worse performance than that of the detectors based entirely on
inorganic scintillators, all of the materials investigated for the scatter
detector have the potential to provide performance adequate for our purposes.Comment: Revised text and figures, Presented at SORMA West 2008, Published in
IEEE Transactions on Nuclear Scienc
Spectral and stratigraphic mapping of hydrated sulfate and phyllosilicate-bearing deposits in northern Sinus Meridiani, Mars
We present detailed stratigraphic and spectral analyses that focus on a region in
northern Sinus Meridiani located between 1°N to 5°N latitude and 3°W to 1°E longitude.
Several stratigraphically distinct units are defined and mapped using morphologic
expression, spectral properties, and superposition relationships. Previously unreported
exposures of hydrated sulfates and Fe/Mg smectites are identified using MRO CRISM and
MEX OMEGA nearâinfrared (1.0 to 2.5 ”m) spectral reflectance observations. Layered
deposits with monohydrated and polyhydrated sulfate spectral signatures that occur in
association with a northeastâsouthwest trending valley are reexamined using highresolution
CRISM, HiRISE, and CTX images. Layers that are spectrally dominated by
monohydrated and polyhydrated sulfates are intercalated. The observed compositional
layering implies that multiple wetting events, brine recharge, or fluctuations in evaporation
rate occurred. We infer that these hydrated sulfateâbearing layers were unconformably
deposited following the extensive erosion of preexisting layered sedimentary rocks and
may postdate the formation of the sulfateâ and hematiteâbearing unit analyzed by the MER
Opportunity rover. Therefore, at least two episodes of deposition separated by an
unconformity occurred. Fe/Mg phyllosilicates are detected in units that predate the sulfateand
hematiteâbearing unit. The presence of Fe/Mg smectite in older units indicates that the
relatively low pH formation conditions inferred for the younger sulfateâ and hematitebearing
unit are not representative of the aqueous geochemical environment that prevailed
during the formation and alteration of earlier materials. Sedimentary deposits indicative of
a complex aqueous history that evolved over time are preserved in Sinus Meridiani, Mars
Surface Geometry of C60 on Ag(111)
The geometry of adsorbed C60 influences its collective properties. We report the first dynamical low-energy electron diffraction study to determine the geometry of a C60 monolayer, Ag(111)-(23Ă23)30°-C60, and related density functional theory calculations. The stable monolayer has C60 molecules in vacancies that result from the displacement of surface atoms. C60 bonds with hexagons down, with their mirror planes parallel to that of the substrate. The results indicate that vacancy structures are the rule rather than the exception for C60 monolayers on close-packed metal surfaces. © 2009 The American Physical Society
Electron Cotunneling in a Semiconductor Quantum Dot
We report transport measurements on a semiconductor quantum dot with a small
number of confined electrons. In the Coulomb blockade regime, conduction is
dominated by cotunneling processes. These can be either elastic or inelastic,
depending on whether they leave the dot in its ground state or drive it into an
excited state, respectively. We are able to discriminate between these two
contributions and show that inelastic events can occur only if the applied bias
exceeds the lowest excitation energy. Implications to energy-level spectroscopy
are discussed.Comment: To be published in Phys. Rev. Let
N-Terminal ProâB-Type Natriuretic Peptide in the Emergency Department: The ICON-RELOADED Study
Background
Contemporary reconsideration of diagnostic N-terminal proâB-type natriuretic peptide (NT-proBNP) cutoffs for diagnosis of heart failure (HF) is needed.
Objectives
This study sought to evaluate the diagnostic performance of NT-proBNP for acute HF in patients with dyspnea in the emergency department (ED) setting.
Methods
Dyspneic patients presenting to 19 EDs in North America were enrolled and had blood drawn for subsequent NT-proBNP measurement. Primary endpoints were positive predictive values of age-stratified cutoffs (450, 900, and 1,800 pg/ml) for diagnosis of acute HF and negative predictive value of the rule-out cutoff to exclude acute HF. Secondary endpoints included sensitivity, specificity, and positive (+) and negative (â) likelihood ratios (LRs) for acute HF.
Results
Of 1,461 subjects, 277 (19%) were adjudicated as having acute HF. The area under the receiver-operating characteristic curve for diagnosis of acute HF was 0.91 (95% confidence interval [CI]: 0.90 to 0.93; p < 0.001). Sensitivity for age stratified cutoffs of 450, 900, and 1,800 pg/ml was 85.7%, 79.3%, and 75.9%, respectively; specificity was 93.9%, 84.0%, and 75.0%, respectively. Positive predictive values were 53.6%, 58.4%, and 62.0%, respectively. Overall LR+ across age-dependent cutoffs was 5.99 (95% CI: 5.05 to 6.93); individual LR+ for age-dependent cutoffs was 14.08, 4.95, and 3.03, respectively. The sensitivity and negative predictive value for the rule-out cutoff of 300 pg/ml were 93.9% and 98.0%, respectively; LRâ was 0.09 (95% CI: 0.05 to 0.13).
Conclusions
In acutely dyspneic patients seen in the ED setting, age-stratified NT-proBNP cutpoints may aid in the diagnosis of acute HF. An NT-proBNP <300 pg/ml strongly excludes the presence of acute HF
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