Deep Learning for Electricity Forecasting Using Time Series Data

The complexity and nonlinearities of the modern power grid render traditional physical modeling and mathematical computation unrealistic. AI and predictive machine learning techniques allow for accurate and efficient system modeling and analysis. Electricity consumption forecasting is highly valuable in energy management and sustainability research. Furthermore, accurate energy forecasting can be used to optimize energy allocation. This thesis introduces Deep Learning models including the Convolutional Neural Network (CNN), the Recurrent neural network (RNN), and Long Short-Term memory (LSTM). The Hourly Usage of Energy (HUE) dataset for buildings in British Columbia is used as an example for our investigation, as the dataset contains data from residential customers of BC Hydro, a provincial power utility company. Due to the temporal dependency in time-series observation data, data preprocessing is required before a model can be created. The LSTM model is utilized to create a predictive model for electricity consumption as output. Approximately 63% of the data is used for training, and the remaining 37% is used for testing. Various LSTM parameters are tested and tuned for best performance. Our LSTM predictive model can facilitate power companies’ resource management decisions

Developing a simulated intelligent instrument to measure user behavior toward cybersecurity policies

Institutions struggle to protect themselves from threats and cybercrime. Therefore, they devote much attention to improving information security infrastructures. Users’ behaviors were explored via a traditional questionnaire research instrument in a data collocate process. The questionnaire explores users’ behaviors theoretically, so the respondents’ answers to the questionnaire are insufficiently reliable, and the responses might not reflect actual behavior based on the human bias when facing theoretical problems. This study aims to solve unreliable responses to the questionnaire by developing a simulated intelligent instrument to measure users’ behaviors toward cybersecurity policies in an experimental study using gamification

Appling tracking game system to measure user behavior toward cybersecurity policies

Institutions wrestle to protect their information from threats and cybercrime. Therefore, it is dedicating a great deal of their concern to improving the information security infrastructure. Users’ behaviors were explored by applying traditional questionnaire as a research instrument in data collocate process. But researchers usually suffer from a lack of respondents' credibility when asking someone to fill out a questionnaire, and the credibility may decline further if the research topic relates to aspects of the use and implementation of information security policies. Therefore, there is insufficient reliability of the respondent's answers to the questionnaire’s questions, and the responses might not reflect the actual behavior based on the human bias when facing the problems theoretically. The current study creates a new idea to track and study the behavior of the respondents by building a tracking game system aligned with the questionnaire whose results are required to be known. The system will allow the respondent to answer the survey questions related to the compliance with the information security policies by tracking their behavior while using the system

The Role Of EI In Effective Leadership, In The Context Of Saudi Arab: A Systematic Review

Background: The field of Emotional Intelligence (EI) is a growing field reflecting its effectiveness in different professions and institutes. There is little evidence available to seek a comprehensive role of EI in effective leadership. This study explores the role of EI in effective leadership. Aim: The aim of this study is to investigate how the component of EI plays an effective role in leadership, in the context of Saudi Arab. Method: For the purpose, a systematic approach was employed to identify and select relevant studies from key databases. Inclusion and exclusion criteria ensured the consideration of studies published within 05 years that examined the role of EI for effective leadership. Data extraction and analysis were conducted to synthesize findings from 11 selected studies. Results: In total 130 articles were explored and only 03 were found very relevant and 28 somewhat relevant based on inclusion criteria. Findings revealed that EI play a key role in any field specifically in effective leadership and leadership skills including empathy, self-management, and self-awareness. However, limitations including selection bias were acknowledged. Conclusion: The study concludes that EI can enhance the leadership role and can bring very significant advancement in the field of leadership. Since, there was no studies found that studied exclusively EI in relation with effective leadership

Echinacoside ameliorates hepatic fibrosis and tumor invasion in rats with thioacetamide-induced hepatocellular carcinoma

Hepatocellular carcinoma (HCC) affects approximately 800,000 individuals globally each year. Despite advancements in HCC treatments, there is still a pressing need to identify new drugs that can combat resistance. One potential option is echinacoside, a natural caffeic acid glycoside with antioxidant, anti-inflammatory, antidepressant, and antidiabetic properties. Therefore, we aimed to investigate the ability of echinacoside to exhibit antitumor activity against HCC in rats through ameliorating hepatic fibrosis and tumor invasion. Rats were given thioacetamide to induce HCC, and some were given 30 mg/kg of echinacoside twice a week for 16 weeks. The liver impairment was assessed by measuring serum α-fetoprotein (AFP) and examining liver sections stained with Masson trichrome or anti-transforming growth factor (TGF)-β1 antibodies. The hepatic expression of mRNA and protein levels of TGF-β1, β-catenin, SMAD4, matrix metalloproteinase-9 (MMP9), phosphoinositide 3-kinases (PI3K), mammalian target of rapamycin (mTOR), connective tissue growth factor 2 (CCN2), E-Cadherin, platelets derived growth factor (PDGF)-B and fascin were also analyzed. Echinacoside improved the survival rate of rats by decreasing serum AFP and the number of hepatic nodules. Examination of micro-images indicated that echinacoside can reduce fibrosis. It also significantly decreased the expression of TGF-β1, β-catenin, SMAD4, MMP9, PI3K, mTOR, CCN2, PDGF-B, and fascin while enhancing the expression of E-Cadherin. In conclusion, echinacoside exhibits a protective effect against HCC by increasing survival rates and decreasing tumor growth. It also acts as an inhibitor of the hepatic tissue fibrosis pathway by reducing the expression of TGF-β1, β-catenin, SMAD4, PI3K, CCN2, PDGF-B and mTOR. Additionally, it prevents tumor invasion by suppressing MMP9 and fascin, and increasing the expression of E-Cadherin

Role of L- glutamine and crizanlizumab in sickle cell anaemia painful crisis reduction

BackgroundPatients with sickle cell disease, frequently ‎ suffer from intense painful episodes. Till recently hydroxyurea was the only available medical therapy that approved for reduction of painful episodes.AimsTo summarize the available data from randomized controlled trials that aim to evaluate the efficacy of newly approved L-‎glutamine‎ (alters redox state of red blood cells ‎‎[RBCs]) ‎and ‎crizanlizumab (‎(anti-P-selectin)‎)‎ ‎on vaso-occlusive episodes in Sickle cell disease ‎ patients.Methods PubMed, ‎Google Scholar, and EBSCO ‎ databases were ‎‎systematically search for relevant articles. The terms ‎ ‎ ‎ L-glutamine, sickle cell disease, sickle cell ‎anaemia,‎ ‎‎crizanlizumab ‎and vaso-occlusive episodes‎ were used.Results Out of Four-hundred seventy-two records, only three fulfilled the inclusion criteria. Two trials were aimed to evaluate the efficacy of L-glutamine therapy on the frequency of painful crises in sickle cell anaemia patients. Both studies showed that L-glutamine therapy significantly reduce the frequency of VOEs. Only one trial examined the ability of crizanlizumab on VOEs reduction, and showed crizanlizumab successful reduce the occurrence of VOEs.‎ConclusionNewer agent ‎with different mechanism of action, such as ‎L-glutamine, ‎and crizanlizumab may consider if ‎hydroxyurea not effective or not ‎tolerable

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

Spectrochemical Series Revisited

The aim of this report is to provide a method of validation and quantification for the spectrochemical series. For this purpose, the paper initially set out to use a modified version of the Jorgensen equation by the incorporation of a geometric factor, H

Healthcare Professionals’ Perspective on Palliative Care in Intensive Care Settings: An Interpretive Descriptive Study

There is a growing need to integrate palliative care into intensive care units and to develop appropriate knowledge translation strategies. However, multiple challenges persist in attempts to achieve this objective. In this study, we aimed to explore intensive care professionals’ perspectives on providing palliative and end-of-life care within an intensive care context. We used an interpretive description approach and interviewed 36 intensive care professionals at four hospitals in Saudi Arabia. Our findings reflect a discourse about end-of-life care driven by a do-not-resuscitate classification and challenges associated with family involvement in care goals. We provide key insights of importance for the development of strategies for the integration and knowledge translation of palliative care into intensive care contexts

Nanoparticles as Drug Delivery Systems: A Review of the Implication of Nanoparticles’ Physicochemical Properties on Responses in Biological Systems

In the last four decades, nanotechnology has gained momentum with no sign of slowing down. The application of inventions or products from nanotechnology has revolutionised all aspects of everyday life ranging from medical applications to its impact on the food industry. Nanoparticles have made it possible to significantly extend the shelf lives of food product, improve intracellular delivery of hydrophobic drugs and improve the efficacy of specific therapeutics such as anticancer agents. As a consequence, nanotechnology has not only impacted the global standard of living but has also impacted the global economy. In this review, the characteristics of nanoparticles that confers them with suitable and potentially toxic biological effects, as well as their applications in different biological fields and nanoparticle-based drugs and delivery systems in biomedicine including nano-based drugs currently approved by the U.S. Food and Drug Administration (FDA) are discussed. The possible consequence of continuous exposure to nanoparticles due to the increased use of nanotechnology and possible solution is also highlighted