A bibliometric methodology for identifying interdisciplinary and collaborative publications

Proceedings paper for a presentation at the 14th European Association for Health Information and Libraries (EAHIL) Conference, 2014, Rome Italy. Also available at http://www.iss.it/binary/eahi/cont/116_Heather_K._Moberly_Full_text.pdf.Abstract Introduction This presentation describes a bibliometric methodology to define an ancillary journal list as a complement to a core journal list. Although it can be applied to any discipline with a core journal literature, this case study data set is research published by faculty at the 28 American Veterinary Medical Association accredited veterinary schools in the United States. This ancillary list identifies interdisciplinary and collaborative publications by analyzing the non-core subject literature. Methods Eleven years of citation data were collected from Web of Knowledge and exported to Excel. Data in several fields were normalized, pivot tables were created, and data were uploaded into Many Eyes visualization tool. The result sets were compared to the current core veterinary serials list. The images from both the pivot tables and Many Eyes showed clear trends in the data for each school and across schools. Results and Conclusions Overall, 56 percent of articles were published in the core veterinary journals. Bradford’s Law and a Bradford-Zipf plot show an enormous breadth of veterinary publications

Exploring the Veterinary Literature: A Bibliometric Methodology for Identifying Interdisciplinary and Collaborative Publications

Veterinary medical research traditionally focuses on animal health and wellness; however, research activities at veterinary colleges extend beyond these traditional areas. In this study, we analyzed eleven years of Web of Knowledge-indexed peer-reviewed articles from researchers at the twenty-eight United States American Veterinary Medical Association (AVMA) accredited veterinary colleges. We had three goals in assessing the published literature of veterinary college researchers. First, we identified a list of journals and research areas outside veterinary medicine in which veterinary researchers publish. This list of journals can be customized to identify those most essential at each institution. Second, we identified collaborative work by veterinary researchers across disciplines and institutions. Using textual analysis tools and visualizations helped us illustrate and clarify these data. Last, we developed a methodology for defining an interdisciplinary serials list outside a subject core that can be customized for specific institutions and subject areas

A bibliometric methodology for identifying interdisciplinary and collaborative publications

Proceedings paper for a presentation at the 14th European Association for Health Information and Libraries (EAHIL) Conference, 2014, Rome Italy. Also available at http://www.iss.it/binary/eahi/cont/116_Heather_K._Moberly_Full_text.pdf.Abstract Introduction This presentation describes a bibliometric methodology to define an ancillary journal list as a complement to a core journal list. Although it can be applied to any discipline with a core journal literature, this case study data set is research published by faculty at the 28 American Veterinary Medical Association accredited veterinary schools in the United States. This ancillary list identifies interdisciplinary and collaborative publications by analyzing the non-core subject literature. Methods Eleven years of citation data were collected from Web of Knowledge and exported to Excel. Data in several fields were normalized, pivot tables were created, and data were uploaded into Many Eyes visualization tool. The result sets were compared to the current core veterinary serials list. The images from both the pivot tables and Many Eyes showed clear trends in the data for each school and across schools. Results and Conclusions Overall, 56 percent of articles were published in the core veterinary journals. Bradford’s Law and a Bradford-Zipf plot show an enormous breadth of veterinary publications

MP756: Eastern Regional Potato Trials 2004: Summary of NE1014 Regional Project Field Testing of New Potato Clones

The objectives of this regional potato trial are (1) to develop pest-resistant, early-maturing, long-dormant potato varieties that will process from cold storage; (2) to evaluate new and specialty variet­ies developed in the Northeast; (3) to determine climatic effects on performance to develop pre­dictive models for potato improvement; and (4) determine heritability/linkage relationships and improve the genetic base of tetraploid cultivated varieties. The results presented in this report reflect a portion of the activity directed toward objectives 1, 2 and 3.https://digitalcommons.library.umaine.edu/aes_miscpubs/1019/thumbnail.jp

MP755: Eastern Regional Potato Trials 2003: Summary of NE1014 Regional Project Field Testing of New Potato Clones

The objectives of this regional potato trial are (1) to develop pest-resistant, early-maturing, long-dormant potato varieties that will process from cold storage; (2) to evaluate new and specialty variet­ies developed in the Northeast; (3) to determine climatic effects on performance to develop pre­dictive models for potato improvement; and (4) determine heritability/linkage relationships and improve the genetic base of tetraploid cultivated varieties. The results presented in this report reflect a portion of the activity directed toward objectives 1, 2 and 3.https://digitalcommons.library.umaine.edu/aes_miscpubs/1020/thumbnail.jp

MP758: East Regional Potato Trials 2006: Summary of NE1014 Regional Project Field Testing of New Potato Clones

The objectives of this regional potato trial are (1) to develop pest-resistant, early-maturing, long-dormant potato varieties that will process from cold storage; (2) to evaluate new and specialty variet­ies developed in the Northeast; (3) to determine climatic effects on performance to develop pre­dictive models for potato improvement; and (4) determine heritability/linkage relationships and improve the genetic base of tetraploid cultivated varieties. The results presented in this report reflect a portion of the activity directed toward objectives 1, 2 and 3.https://digitalcommons.library.umaine.edu/aes_miscpubs/1017/thumbnail.jp

MP760: East Regional Potato Trials 2007: Summary of NE1014 Regional Project Field Testing of New Potato Clones

The objectives of this regional potato trial are (1) to develop pest-resistant, early-maturing, long-dormant potato varieties that will process from cold storage; (2) to evaluate new and specialty variet­ies developed in the Northeast; (3) to determine climatic effects on performance to develop pre­dictive models for potato improvement; and (4) determine heritability/linkage relationships and improve the genetic base of tetraploid cultivated varieties. The results presented in this report reflect a portion of the activity directed toward objectives 1, 2 and 3.https://digitalcommons.library.umaine.edu/aes_miscpubs/1016/thumbnail.jp

Long-Term Land Use Affects Phosphorus Speciation and the Composition of Phosphorus Cycling Genes in Agricultural Soils

Agriculturally-driven land transformation is increasing globally. Improving phosphorus (P) use efficiency to sustain optimum productivity in diverse ecosystems, based on knowledge of soil P dynamics, is also globally important in light of potential shortages of rock phosphate to manufacture P fertilizer. We investigated P chemical speciation and P cycling with solution 31P nuclear magnetic resonance, P K-edge X-ray absorption near-edge structure spectroscopy, phosphatase activity assays, and shotgun metagenomics in soil samples from long-term agricultural fields containing four different land-use types (native and tame grasslands, annual croplands, and roadside ditches). Across these land use types, native and tame grasslands showed high accumulation of organic P, principally orthophosphate monoesters, and high acid phosphomonoesterase activity but the lowest abundance of P cycling genes. The proportion of inositol hexaphosphates (IHP), especially the neo-IHP stereoisomer that likely originates from microbes rather than plants, was significantly increased in native grasslands than croplands. Annual croplands had the largest variances of soil P composition, and the highest potential capacity for P cycling processes based on the abundance of genes coding for P cycling processes. In contrast, roadside soils had the highest soil Olsen-P concentrations, lowest organic P, and highest tricalcium phosphate concentrations, which were likely facilitated by the neutral pH and high exchangeable Ca of these soils. Redundancy analysis demonstrated that IHP by NMR, potential phosphatase activity, Olsen-P, and pH were important P chemistry predictors of the P cycling bacterial community and functional gene composition. Combining chemical and metagenomics results provides important insights into soil P processes and dynamics in different land-use ecosystems

Global Genetic Structure and Molecular Epidemiology of Encapsulated Haemophilus influenzae

A collection of 2,209 isolates of six polysaccharide capsule types of Haemophilus influenzoe, including 1,975 serotype b isolates recovered in 30 countries was characterized for electrophoretically demonstrable allele profiles at 17 metabolic enzyme loci. Two hundred eighty distinct multilocus genotypes were distinguished, and cluster analysis revealed two primary phylogenetic divisions. The population structure of encapsulated H. influenzae is clonal. Currently, most of the invasive disease worldwide is caused by serotype b strains of nine clones, Strains producing serotype c, e, and f capsules belong to single divisions and have no close genetic relationships to strains of other serotypes, Serotype a and b strains occur in both primary phylogenetic divisions, probably as a result of transfer and recombination of serotype-specific sequences of the cap region between clonal lineages. A close genetic relatedness between serotype d isolates and some strains of serotypes a and b was identified, There are strong patterns of geographic variation, on an intercontinental scale, in both the extent of genetic diversity and the clonal composition of populations of encapsulated strains, The analysis suggests that the present distribution of clones is, in part, related to patterns of racial or ethnic differentiation and historical demographic movements of the human host population

Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors

New arylthioindole derivatives having different cyclic substituents at position 2 of the indole were synthesized as anticancer agents. Several compounds inhibited tubulin polymerization at submicromolar concentration and inhibited cell growth at low nanomolar concentrations. Compounds 18 and 57 were superior to the previously synthesized 5. Compound 18 was exceptionally potent as an inhibitor of cell growth: it showed IC₅₀ = 1.0 nM in MCF-7 cells, and it was uniformly active in the whole panel of cancer cells and superior to colchicine and combretastatin A-4. Compounds 18, 20, 55, and 57 were notably more potent than vinorelbine, vinblastine, and paclitaxel in the NCI/ADR-RES and Messa/Dx5 cell lines, which overexpress P-glycoprotein. Compounds 18 and 57 showed initial vascular disrupting effects in a tumor model of liver rhabdomyosarcomas at 15 mg/kg intravenous dosage. Derivative 18 showed water solubility and higher metabolic stability than 5 in human liver microsomes