407 research outputs found
Witnessing causal nonseparability
Our common understanding of the physical world deeply relies on the notion
that events are ordered with respect to some time parameter, with past events
serving as causes for future ones. Nonetheless, it was recently found that it
is possible to formulate quantum mechanics without any reference to a global
time or causal structure. The resulting framework includes new kinds of quantum
resources that allow performing tasks - in particular, the violation of causal
inequalities - which are impossible for events ordered according to a global
causal order. However, no physical implementation of such resources is known.
Here we show that a recently demonstrated resource for quantum computation -
the quantum switch - is a genuine example of "indefinite causal order". We do
this by introducing a new tool - the causal witness - which can detect the
causal nonseparability of any quantum resource that is incompatible with a
definite causal order. We show however that the quantum switch does not violate
any causal nequality.Comment: 15 + 12 pages, 5 figures. Published versio
Quantum resolution of black hole singularities
We study the classical and quantum theory of spherically symmetric spacetimes
with scalar field coupling in general relativity. We utilise the canonical
formalism of geometrodynamics adapted to the Painleve-Gullstrand coordinates,
and present a new quantisation of the resulting field theory. We give an
explicit construction of operators that capture curvature properties of the
spacetime and use these to show that the black hole curvature singularity is
avoided in the quantum theory.Comment: 5 pages, version to appear in CQ
Vacuum Fluctuations, Geometric Modular Action and Relativistic Quantum Information Theory
A summary of some lines of ideas leading to model-independent frameworks of
relativistic quantum field theory is given. It is followed by a discussion of
the Reeh-Schlieder theorem and geometric modular action of Tomita-Takesaki
modular objects associated with the quantum field vacuum state and certain
algebras of observables. The distillability concept, which is significant in
specifying useful entanglement in quantum information theory, is discussed
within the setting of general relativistic quantum field theory.Comment: 26 pages. Contribution for the Proceedings of a Conference on Special
Relativity held at Potsdam, 200
Analytic Metaphysics versus Naturalized Metaphysics: The Relevance of Applied Ontology
The relevance of analytic metaphysics has come under criticism: Ladyman & Ross, for instance, have suggested do discontinue the field. French & McKenzie have argued in defense of analytic metaphysics that it develops tools that could turn out to be useful for philosophy of physics. In this article, we show first that this heuristic defense of metaphysics can be extended to the scientific field of applied ontology, which uses constructs from analytic metaphysics. Second, we elaborate on a parallel by French & McKenzie between mathematics and metaphysics to show that the whole field of analytic metaphysics, being useful not only for philosophy but also for science, should continue to exist as a largely autonomous field
Comparison of family health history in surveys vs electronic health record data mapped to the observational medical outcomes partnership data model in the All of Us Research Program
OBJECTIVE: Family health history is important to clinical care and precision medicine. Prior studies show gaps in data collected from patient surveys and electronic health records (EHRs). The All of Us Research Program collects family history from participants via surveys and EHRs. This Demonstration Project aims to evaluate availability of family health history information within the publicly available data from All of Us and to characterize the data from both sources.
MATERIALS AND METHODS: Surveys were completed by participants on an electronic portal. EHR data was mapped to the Observational Medical Outcomes Partnership data model. We used descriptive statistics to perform exploratory analysis of the data, including evaluating a list of medically actionable genetic disorders. We performed a subanalysis on participants who had both survey and EHR data.
RESULTS: There were 54 872 participants with family history data. Of those, 26% had EHR data only, 63% had survey only, and 10.5% had data from both sources. There were 35 217 participants with reported family history of a medically actionable genetic disorder (9% from EHR only, 89% from surveys, and 2% from both). In the subanalysis, we found inconsistencies between the surveys and EHRs. More details came from surveys. When both mentioned a similar disease, the source of truth was unclear.
CONCLUSIONS: Compiling data from both surveys and EHR can provide a more comprehensive source for family health history, but informatics challenges and opportunities exist. Access to more complete understanding of a person\u27s family health history may provide opportunities for precision medicine
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