Anti-Inflammatory Activity of Babassu Oil and Development of a Microemulsion System for Topical Delivery

Babassu oil extraction is the main income source in nut breakers communities in northeast of Brazil. Among these communities, babassu oil is used for cooking but also medically to treat skin wounds and inflammation, and vulvovaginitis. This study aimed to evaluate the anti-inflammatory activity of babassu oil and develop a microemulsion system with babassu oil for topical delivery. Topical anti-inflammatory activity was evaluated in mice ear edema using PMA, arachidonic acid, ethyl phenylpropiolate, phenol, and capsaicin as phlogistic agents. A microemulsion system was successfully developed using a Span® 80/Kolliphor® EL ratio of 6 : 4 as the surfactant system (S), propylene glycol and water (3 : 1) as the aqueous phase (A), and babassu oil as the oil phase (O), and analyzed through conductivity, SAXS, DSC, TEM, and rheological assays. Babassu oil and lauric acid showed anti-inflammatory activity in mice ear edema, through inhibition of eicosanoid pathway and bioactive amines. The developed formulation (39% A, 12.2% O, and 48.8% S) was classified as a bicontinuous to o/w transition microemulsion that showed a Newtonian profile. The topical anti-inflammatory activity of microemulsified babassu oil was markedly increased. A new delivery system of babassu microemulsion droplet clusters was designed to enhance the therapeutic efficacy of vegetable oil

Fishers’ knowledge indicates short-term temporal changes in the amount and composition of catches in the southwestern Atlantic

The scarcity of data on fish catches difficult management of small-scale fisheries in developing countries. This study applies fishers' knowledge to investigate temporal changes in the amount (biomass) and composition (major ecological categories) of fishing resources exploited by small-scale coastal fisheries in the southeastern Brazilian coast. Four hypotheses were investigated: (1) The amount of fish caught reported by fishers would decrease over time. (2) Older fishers would report higher fish catches than younger fishers. (3) Recent interviews would mention large-sized predators less often. (4) Recent interviews would mention less high valued fishing resources. Interviews with 421 fishers in 36 communities in the southeastern Brazilian coast were analyzed, covering a time span of 14 years, from 1995 to 2009. The hypothesis 1 was confirmed, 3 was partially confirmed, while 2 and 4 were not confirmed. Fishers' age was unrelated to all variables. The results from fishers' interviews indicated the temporal trends of: (1) a decrease in the biomass of fish caught; (2) an increase in the occurrence of smaller fish and invertebrates in the catch; (3) an increase of high value fishing resources; and (4) maintenance of large predators. The first two indicators suggest excessive fishing, but the later indicators (3 and 4) suggest that the socioecological system of the southeastern Brazilian coast had not yet undergone major ecological shifts71111120CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP309014/2013-143/201397/06167-0; 01/00718-1; 04/02301-9; 06/50435-0; 07/58700-7; 2009/11154-3; 2012/16722-

Fishers' knowledge identifies environmental changes and fish abundance trends in impounded tropical rivers

The long-term impacts of large hydroelectric dams on small-scale fisheries in tropical rivers are poorly known. A promising way to investigate such impacts is to compare and integrate the local ecological knowledge (LEK) of resource users with biological data for the same region. We analyzed the accuracy of fishers’ LEK to investigate fisheries dynamics and environmental changes in the Lower Tocantins River (Brazilian Amazon) downstream from a large dam. We estimated fishers’ LEK through interviews with 300 fishers in nine villages and collected data on 601 fish landings in five of these villages, 22 years after the dam’s establishment (2006–2008). We compared these two databases with each other and with data on fish landings from before the dam’s establishment (1981) gathered from the literature. The data obtained based on the fishers’ LEK (interviews) and from fisheries agreed regarding the primary fish species caught, the most commonly used type of fishing gear (gill nets) and even the most often used gill net mesh sizes but disagreed regarding seasonal fish abundance. According to the interviewed fishers, the primary environmental changes that occurred after the impoundment were an overall decrease in fish abundance, an increase in the abundance of some fish species and, possibly, the local extinction of a commercial fish species (Semaprochilodus brama). These changes were corroborated by comparing fish landings sampled before and 22 years after the impoundment, which indicated changes in the composition of fish landings and a decrease in the total annual fish production. Our results reinforce the hypothesis that large dams may adversely affect small-scale fisheries downstream and establish a feasible approach for applying fishers’ LEK to fisheries management, especially in regions with a low research capacity

Appendix D. Categories of answers of the interviewed fishers to questions about environmental changes and the reasons for such changes in fish abundance.

Categories of answers of the interviewed fishers to questions about environmental changes and the reasons for such changes in fish abundance

Appendix B. Survey used to quantify the species and biomasses of fish caught and type of fishing gear used by fishers in the Lower Tocantins River in the Brazilian Amazon.

Survey used to quantify the species and biomasses of fish caught and type of fishing gear used by fishers in the Lower Tocantins River in the Brazilian Amazon

Consumo de Peixes na Amazônia: uma revisão sobre biodiversidade, hidrelétricas e segurança alimentar

The lack of knowledge about the majority of fish species harvested in Amazonian small-scale fisheries, in association with impacts from hydroelectric power plants, may lead to biodiversity loss and a decrease in the protein food supply for riverine Amazonians. This study uses existing datasets on fisheries and riverine developmental projects to infer effects associated with fish losses where actual data and outcomes are not available. The targeted fish species' status may be regarded as either threatened or there being no knowledge of their conservation requirements, biology or ecology. Among the 90 Amazonian fish species that are the most important for the diet of the riverine fishers, 78% are not assessed or their biological information is unknown, according to the IUCN Red List. Consequently, the effects created by the thoroughly disregarded trade-off between energy generation and food security in the planning of Amazonian land use have been worsened by the lack of biological and ecological information on fish species792345357CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPsem informação14/24994-8The lack of knowledge about the majority of fish species harvested in Amazonian small-scale fisheries, in association with impacts from hydroelectric power plants, may lead to biodiversity loss and a decrease in the protein food supply for riverine Amazonians. This study uses existing datasets on fisheries and riverine developmental projects to infer effects associated with fish losses where actual data and outcomes are not available. The targeted fish species' status may be regarded as either threatened or there being no knowledge of their conservation requirements, biology or ecology. Among the 90 Amazonian fish species that are the most important for the diet of the riverine fishers, 78% are not assessed or their biological information is unknown, according to the IUCN Red List. Consequently, the effects created by the thoroughly disregarded trade-off between energy generation and food security in the planning of Amazonian land use have been worsened by the lack of biological and ecological information on fish species.FAPESPFundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [14/24994-8]; ANU's Brazilian Regional Reference Group Collaboration Scheme (Australia); CNPqNational Council for Scientific and Technological Development (CNPq

Appendix F. Correlation plot of the frequencies of 11 distinct gill net mesh sizes observed and reported by fishers.

Correlation plot of the frequencies of 11 distinct gill net mesh sizes observed and reported by fishers

Fish consumption on the Amazon: a review of biodiversity, hydropower and food security issues

Abstract The lack of knowledge about the majority of fish species harvested in Amazonian small-scale fisheries, in association with impacts from hydroelectric power plants, may lead to biodiversity loss and a decrease in the protein food supply for riverine Amazonians. This study uses existing datasets on fisheries and riverine developmental projects to infer effects associated with fish losses where actual data and outcomes are not available. The targeted fish species’ status may be regarded as either threatened or there being no knowledge of their conservation requirements, biology or ecology. Among the 90 Amazonian fish species that are the most important for the diet of the riverine fishers, 78% are not assessed or their biological information is unknown, according to the IUCN Red List. Consequently, the effects created by the thoroughly disregarded trade-off between energy generation and food security in the planning of Amazonian land use have been worsened by the lack of biological and ecological information on fish species