Determination of Fatty Acid, C, H, N and Trace Element Composition in Grape Seed by GC/MS, FTIR, Elemental Analyzer and ICP/OES

Abstract: Four different methods were used for the investigation of fatty acid, C, H, N and trace element composition of grape seed oil and pulp. The fatty acid profile of the grape seed oil was measured by GC/MS. Moreover, structural analysis of the oil was carried out by FT/IR spectrometry with a Zn Se ATR accessory. The quantification of selected metals Na, K, Mg, Ca, Mn, Fe, Zn and Cu in grape seed oil and pulp was carried out using microwave assisted digestion followed by ICP/OES. Grape seed was analyzed for C, H and N by elemental analyzer

Spectrophotometric determination of acid dissociation constants of some arylpropionic acids and arylacetic acids in acetonitrile-water binary mixtures at 25º C

The acid dissociation constant of drug active compounds (arylpropionic and aryl acetic acids) were determined in acetonitrile and water binary mixtures (corresponding volume fractions of 0.40, 0.45, 0.50, and 0.55) by using a multi-wavelength spectrophotometric method. Drug active compounds, which were slightly soluble in water, were studied in these binary mixtures. The dissociation constants of drug active compounds are important in drug design studies and in any research of the biopharmaceutical and physicochemical properties of drugs. The STAR program was used for the determination of dissociation constants. The acidity constants of arylpropionic and aryl acetic acids were correlated with the Kamlet and Taft solvaatochromic parameters. Aqueous pKa values of these arylpropionic and aryl acetic acids were determined from pKa values obtained from acetonitrile and water binary mixtures with varying volume fractions. The studied drugs had a pKa value corresponding to base functional group. Results showed that the acid dissociation constant values of the drug active compounds increased with an increase in acetonitrile content in the medium

Analysis of acrylamide in drinking water by SPE and GC–MS

Abstract The present study aimed to evaluate the levels of acrylamide in drinking water by solid phase extraction (SPE). After SPE, water extracts were analyzed using gas chromatography–mass spectrometry (GC–MS) system. Thirty drinking water samples were analyzed in the study. Acrylamide was detected in 12 samples. The levels of acrylamide in drinking water samples were less than 85 ng l−1. The limit of detection and limit of quantification were 4 and 13.20 ng l−1, respectively

Eskişehir'de Halk Arasında Kullanılan Bazı Bitkilerdeki Ağır Metal ve Besin Elementlerinin Belirlenmesi

In this study, the leaves of sheep sorrel (Rumex acetosella L), nettle (Urtica dioica L), rosemary (Rosmarinus officinalis L.) and walnut (Juglansregia L.) that are used as medicinal plant and especially as food were collected from the gardens and their commercial samples were purchased from Eskişehir bazaa

Türk Siyah Çayı, Hazır Kahve ve Türk Kahvesi Örneklerinin Akrilamid İçeriği

Bu çalışmada, Türk ve hazır kahve ile siyah çay örneklerinin akrilamid içerikleri, herhangi bir türevlendirme basamağı olmadan gaz kromatografisi kütle spektrometrisi ile belirlenmiştir. Numune hazırlama yöntemi iki aşamadan oluşmaktadır.  İlk basamak, izolasyon aşamasıdır.  Bu adımda, etanol ile Carrez I ve II çözeltileri örnek karışımlarına eklenmiştir. Katı faz ekstraksiyonu ikinci adımı oluşturmaktadır. Çalışmada, C18 kartuşu temizleme için kullanılmıştır. Tespit ve tayin limiti sırasıyla 1,11 ve 3,66 ng/mL’dir. Sekiz hazır kahve örneğinde 4,48 ile 15,71 µg/kg arasında değişen akrilamid miktarı belirlenmiştir. Yedi Türk kahvesi numunesi ise, 3,89 ile 88,44 µg/kg arasında değişen yüksek bir akrilamid içeriğine sahiptir. On yedi siyah çay numunesinden sadece beş tanesinde, 7,02 ile 19,85 µg/kg arasında değişen miktarda akrilamid tespit edilmiştir

Dondurularak Saklanan Kirazlardaki Pestisit Kalıntı Miktarlarının Zamanla Değişimi

The aim ofthis study was to determine changes over time in pesticide residue amounts on cherries which were frozen unwashed and after being washed. Cherries collected from Senirkent region (Isparta) were divided into two groups as washed and unwashed. The samples were stored at -20 °C for six months. Pesticide residues analyses were carried out through the use of gas chromatography device. The first chromatographic analysis was performed on the day when cherries were collected. Analyses were repeated once a month during storage period (six month). In this way, changes in pesticide residue amounts were determined for the washed and unwashed cherries that were kept frozen. According to results obtained, while there happened a decrease in pesticide residue amounts for the washed cherries kept frozen, this decreased was periodical (first day 0,6 mg/kg, at the endof the sixth month 0,2 mg/kg). On the other hand, it was found that decrease in pesticide residue amounts for the unwashed cherries fell off as freezing storage period increased (first day 1,1mg/kg, at the end of the sixth month 0,1 mg/kg

Seçilen Bazı Pestisitlerin Bal Örneklerinde Analizi

Bu çalışmada, Isparta'dan temin edilmiş bal örneklerinde pestisit analizi yapılmıştır. Pestisit analizleri, katı faz ekstraksiyon (SPE) işleminden sonra, gaz kromatografi/azot fosfor dedektörü (GC/NPD) kullanılarak gerçekleştirilmiştir. On adet pestisit kalıntısı analizi, yirmi adet örnekte yapılmıştır. Çalışılan pestisitlerin, GC/NPD kullanılarak elde edilen dedeksiyon limitler 0.5-3.50 ng/g arasındadır. Elde edilen geri kazanma değerleri % 84,4 ile % 90,8 aralığındadır. Klorpirifos (0,024 ng/g), diazinon (0,021 ng/g), ethion (0,046 ng/g), sipermetrin (0,021 ng/g), deltametrin (0,019 ng/g) ve malathion (0,020 ng/g) kalıntıları bal örneklerinde tespit edilmiştir

The role of bio-detection dogs in the prevention and diagnosis of infectious diseases: A systematic review

nfectious diseases have been lately considered as one of the most important global risks, which negatively impact not only the health but also the socioeconomic conditions of countries. Globalization influences the spread of infectious diseases as a result of increased travelling and interaction in humans. Thus, it is highly important to prevent and diagnose new infectious diseases by using accurate and quick diagnostic methods. Bio-detection dogs have a great potential to accurately diagnose infectious disease as they have a great ability to sense diseasespecific volatile organic compounds (VOCs) originate from infectious agents and/or pathophysiological processes in the human body. The use of these dogs to detect infectious diseases has come to focus in particular after the recent global health crisis due to the SARSCoV-2 infection.This review discusses the potential use of bio-detection dogs in the prevention and diagnosing of infectious diseases. Moreover, factors affecting the scent of the disease, e.g. VOCs, are tried to be highlighted.Bulaşıcı hastalıklar, son zamanlarda sadece ülkelerin sağlığını değil, ekonomisini de olumsuz yönde etkBulaşıcı hastalıklar, son zamanlarda sadece ülkelerin sağlığını değil, ekonomisini de olumsuz yönde etkileyen en önemli küresel risklerden biri olarak kabul edilmektedir. Küreselleşme, yeni insan seyahat modellerinin ve artan insan etkileşiminin bir sonucu olarak bulaşıcı hastalıkların yayılmasını etkilemektedir. Dolayısıyla yeni bulaşıcı hastalıkların doğru ve hızlı teşhis yöntemleri kullanılarak önlenmesi ve teşhis edilmesi büyük önem taşımaktadırileyen en önemli küresel risklerden biri olarak kabul edilmektedir. Küreselleşme, yeni insan seyahat modellerinin ve artan insan etkileşiminin bir sonucu olarak bulaşıcı hastalıkların yayılmasını etkilemektedir. Dolayısıyla yeni bulaşıcı hastalıkların doğru ve hızlı teşhis yöntemleri kullanılarak önlenmesi ve teşhis edilmesi büyük önem taşımaktadır. Biyodedektör köpekler, insan vücudundaki (pato)fizyolojik süreçler sırasında oluşan hastalığa özgü uçucu organik bileşikleri (VOC'ler) ayırt etme konusunda büyük bir yeteneğe sahip oldukları için bulaşıcı hastalıkları doğru bir şekilde teşhis etmede önemli bir potansiyele sahiptir. Bu köpeklerin enfeksiyöz hastalıkları teşhis etmek için kullanılması özellikle SARS-CoV-2 enfeksiyonu nedeniyle yakın zamanda yaşanan küresel sağlık krizinden sonra araştırmaların odak noktası haline gelmiştir. Bu derleme, bulaşıcı hastalıkların önlenmesi ve teşhisinde biyodedektör köpeklerinin potansiyel kullanımını tartışmaktadır. Ayrıca hastalık kokusunu etkileyen faktörler yani VOC'ler de aydınlatılmaya çalışılmıştır.WOS:0006362251000122-s2.0-8510381994

Autoxidized Oleic Acid Bifunctional Macro Peroxide Initiators for Free Radical and Condensation Polymerization. Synthesis and Characterization of Multiblock Copolymers

Secilmis Canbay, Hale/0000-0002-3783-8064; Hazer, Baki/0000-0001-8770-805XWOS: 000491549500023TARAMASCOPUSIndex: SCI-E, WOS, ScopusTARAMAWOSAutoxidation of unsaturated fatty acids gives fatty acid macroperoxide initiators containing two functionalities which can lead to free radical and condensation polymerizations in a single pot. The oleic acid macroperoxide initiator obtained by ecofriendly autoxidation (Pole4m) was used in both the free radical polymerization of styrene and the condensation polymerization with amine-terminated polyethylene glycol (PEGNH2) to obtain triblock branched graft copolymers. The narrow molar masses of the poly oleic acid-g-styrene (PoleS) and poly oleic acid-g-styrene-g-PEG (PoSG) graft copolymers were successfully obtained. The inclusion of oleic acid decreased the glass transition temperature of the polystyrene segment because of the plasticizing effect of oleic acid. In addition, a mechanical property of the copolymer was improved when compared with the pure PS. Structural characterization, morphology of the fracture surface, micelle formation, thermal analysis and molar masses of the obtained products were also evaluated.Kapadokya University Research Fund [KUN.2018-BAGP-001]; Bulent Ecevit University Research FundBulent Ecevit University [BEU-2017-72118496-01]This work was supported by the Kapadokya University Research Fund (KUN.2018-BAGP-001) and Bulent Ecevit University Research Fund (#BEU-2017-72118496-01). The Authors thank to Koray Alper and Fatih Pekdemir for taking SEM and FTIR spectra, respectively. The Authors thank to Serdar Coban, Sidika Sarac Tabakli and Gulsen Darici (Cilas Kaucuk, Devrek, Zonguldak, Turkey) for taking stress-strain measurements