23 research outputs found

    The Extent to Which Arabic Language Teachers Employ Creative Thinking and Technology in the Teaching Methods Implemented by Them

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    The study aimed to identify the extent to which Arabic language teachers employ creative teaching and technology in the teaching methods implemented by them. The researcher adopted the descriptive analytical approach in conducting the study, and the research sample consisted of (50) Arabic language teachers in government schools in the central region of the Jordanian Ministry of Education. The researcher relied on the questionnaire as a tool for data collection, and used statistical methods to extract the results. One of the most prominent results of the study is that the percentage of application of creative teaching methods is generally large among Arabic language teachers, and that Arabic language teachers relied on employing methods that allow students to generate different ideas to a very large degree. And that the lowest percentage of application in the axis of creative teaching methods from the point of view of teachers of Arabic language was to guide students to solve problems in more than one way. Keywords: Arabic language teachers' employment of creative thinking and technology, teaching methods. DOI: 10.7176/JEP/13-31-06 Publication date: November 30th 202

    Permeation through the Cell Membrane of a Boron-Based β-Lactamase Inhibitor

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    Bacteria express beta-lactamases to counteract the beneficial action of antibiotics. Benzo[b]-thiophene-2-boronic acid (BZB) derivatives are β-lactamase inhibitors and, as such, promising compounds to be associated with β-lactam antibacterial therapies. The uncharged form of BZB, in particular, is suggested to diffuse through the outer membrane of Gram negative bacteria. In this study, through the combination of electrophysiological experiments across reconstituted PC/n-decane bilayers and metadynamics-based free energy calculations, we investigate the permeation mechanism of boronic compounds. Our experimental data establish that BZB passes through the membrane, while computer simulations provide hints for the existence of an aqueous, water-filled monomolecular channel. These findings provide new perspectives for the design of boronic acid derivatives with high membrane permeability
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