Einsatz von Kräutern, Tonmineralien und Effektiven Mikroorganismen zur Prophylaxe des Absetzdurchfalles

The effect of an herbal blend (Flos Chamomillae, Fruct. Myrtilli, Rad. Taraxaci, Herba Rhapontici Carthamoides, Rad. Dauci Carotae, Bulbus Allii Sativi) in combination with zeolite and Effective Microorganisms on diarrhea incidence of weaning pigs was studied. 82 healthy piglets were divided into four groups by compensating randomization: treatment and control and for both light and heavy. The animals of the experimental group were administered the herbal blend orally. The piglets were weighed regularly. Faeces were appraised with a faecal score on a scale from 0 (formed faeces) to 2 (fluid faeces). Diarrhea occurred in all groups. Blood sample collections were performed for analysis of haptoglobin and nonesterified fatty acids. The results showed no significant difference between experimental and control group. Considering the piglets of the light group a significant higher daily weight gain in the experimental group was found (327 g vs. 241 g, p = 0.0126). There was also a clear trend (p = 0.0603) toward faecal scores being lower in the light treatment group. Heavy piglets were not affected by eating the herbs. Our results showed that, while this particular herbal blend did not prevent diarrhea in piglets after weaning, it lessened the severity of diarrhea and significantly improved weight gains in the light treated piglets compared with the light untreated piglets

Kräuter für Nutz- und Heimtiere: Ratgeber für die Anwendung ausgewählter Heil- und Gewürzpflanzen

Dieser Ratgeber führt wissenschaftliche Erkenntnisse und traditionelles Hausmittelwissen zusammen, beleuchtet alles Wissenswerte zu über 50 Heilpflanzen und gibt konkrete Anwendungsbeispiele. Ziel ist es, altbewährte Pflanzenanwendungen wieder mehr in die moderne Tierhaltung einzubinden. Der anwenderorientierte Aufbau des Buches ermöglicht es dem Leser, Kenntnisse über die verschiedenen Zubereitungen und Anwendungen von Heilpflanzen zu erwerben und diese in der Praxis einzusetzen. Zubereitung, Aufbewahrung und Anwendung von Kräutern, sowie deren Wirkung und Einsatz bei einzelnen Tierarten werden ausführlich dargestellt. „Die Aufgabe heutiger Wissenschaft ist weniger die Suche nach neuen wirksamen Pflanzen, vielmehr die Überprüfung und Absicherung dieses althergebrachten Wissensschatzes im Lichte moderner Erkenntnisse. Das Autorenteam setzt sich aus jungen engagierten Wissenschaftlern und Tierärzten zusammen. Ihnen ist es ein großes Anliegen, dass die Erkenntnisse der Kräuterheilkunde möglichst vielen Tierhaltern – insbesondere ihren Tieren – von Nutzen sein werden. Es bleibt der Wunsch: die vielen praktischen Anleitungen mögen einen starken Impuls zur Wiederbelebung der Kräuterheilkunde bei Tieren geben.“ Dr. Gerhard Plakol

Clozapine modulates retinoid homeostasis in human brain and normalizes serum retinoic acid deficit in patients with schizophrenia

The atypical antipsychotic clozapine is one of the most potent drugs of its class, yet its precise mechanisms of action remain insufficiently understood. Recent evidence points toward the involvement of endogenous retinoic acid (RA) signaling in the pathophysiology of schizophrenia. Here we investigated whether clozapine may modulate RA-signaling. Effects of clozapine on the catabolism of all-trans RA (at-RA), the biologically most active metabolite of Vitamin A, were assessed in murine and human brain tissue and peripheral blood-derived mononuclear cells (PBMC). In patients with schizophrenia with and without clozapine treatment and matched healthy controls, at-RA serum levels and blood mRNA expression of retinoid-related genes in PBMCs were quantified. Clozapine and its metabolites potently inhibited RA catabolism at clinically relevant concentrations. In PBMC-derived microsomes, we found a large interindividual variability of the sensitivity toward the effects of clozapine. Furthermore, at-RA and retinol serum levels were significantly lower in patients with schizophrenia compared with matched healthy controls. Patients treated with clozapine exhibited significantly higher at-RA serum levels compared with patients treated with other antipsychotics, while retinol levels did not differ between treatment groups. Similarly, in patients without clozapine treatment, mRNA expression of RA-inducible targets CYP26A and STRA6, as well as at-RA/retinol ratio, were significantly reduced. In contrast, clozapine-treated patients did not differ from healthy controls in this regard. Our findings provide the first evidence for altered peripheral retinoid homeostasis in schizophrenia and suggest modulation of RA catabolism as a novel mechanism of action of clozapine, which may be useful in future antipsychotic drug development

A Central Clearing Clinic to Provide Mental Health Services for Refugees in Germany

Objective: To determine migration related distress pattern in refugees and feasibility of a de novo established, central low-threshold outpatient clinic serving more than 80,000 newly arrived refugees in the metropole of Berlin. Methods: In an observational cohort study the relative prevalence of major psychiatric disorders by age, place of living within berlin, language and region of origin were assessed in a refugee cohort from 63 nationalities speaking 36 languages. Findings: Within 18 months, a total of 3,096 cases with a mean age of 29.7 years (11.7) have been referred from all 12 districts and 165 of 182 subdistricts of Berlin to the CCC. 33.7% of the patients were female. The three most frequent diagnoses were unipolar depression (40.4%), posttraumatic stress disorder (24.3%), and adjustment disorder (19.6%). Conclusion: The present data gives insight into the distribution of mental disorders in a large sample of refugees and provides evidence that a CCC is an effective service to quickly and broadly provide psychiatric consultations and thus to overcome classical barriers refugees usually experience in the host communities. In Berlin, Germany, and Europe treatment resources for this population should focus on stress and trauma related disorders

Widespread occurrence of anomalous C-band backscatter signals in arid environments caused by subsurface scattering

Backscatter measured by scatterometers and Synthetic Aperture Radars is sensitive to the dielectric properties of the soil and normally increases with increasing soil moisture content. However, when the soil is dry, the radar waves penetrate deeper into the soil, potentially sensing subsurface scatterers such as near-surface rocks and stones. In this paper we propose an exponential model to describe the impact of such subsurface scatterers on C-Band backscatter measurements acquired by the Advanced Scatterometer (ASCAT) on board of the METOP satellites. The model predicts an increase of the subsurface scattering contributions with decreasing soil wetness that may counteract the signal from the soil surface. This may cause anomalous backscatter signals that deteriorate soil moisture retrievals from ASCAT. We test whether this new model is able to explain ASCAT observations better than a bare soil backscatter model without a subsurface scattering term, using k-fold cross validation and the Bayesian Information Criterion for model selection. We find that arid landscapes with Leptosols and Arenosols represent ideal environmental conditions for the occurrence of subsurface scattering. Nonetheless, subsurface scattering may also become important in more humid environments during dry spells. We conclude that subsurface scattering is a widespread phenomenon that (i) needs to be accounted for in active microwave soil moisture retrievals and (ii) has a potential for soil mapping, particularly in arid and semi-arid environments

The Lantern, 2014-2015

• The Retreat • Part of Eve\u27s Discussion • Buchanan • Hypotheticals • The Baby Hippo • Sertraline and Cheerios • Margins • Anatomy of Me • Orange • Ode to Mathematics • Garden Path • Periphery • 10n Power=Our Maybe Domains • Hillside • Baltimore//Analogues • Work is a Religion • At the Bridal Shower • November • Revisionist History • Cold Front • Lung (for D. Avitabile) • Tether • Hold Still • Reverb • An Almost English Major and His Daughter • Clocks • In the Kitchen on a Sunday Afternoon • Amy • Nine • Customary Thoughts • Showers • Te Encuentro • I Find You • Literary Analysis • The Diamond on My Face • Catherine • Hunsberger Woods, 11:42 on a School Night • Cabbage • After Class • For Chell • To Whom It May Concern • Contra • Shards • Smoke and Roses • Polaroid • Spring\u27s Debut • The Deadline • A Previous Life • Wet Canvas • Obsessions and Compulsions • For Xandra • The Seagulls of 17th Street • No Man\u27s Land • Summer Flowers • Float • Dana Reads • A Barcelona Moment • Business Meeting • Posted • Champagnehttps://digitalcommons.ursinus.edu/lantern/1181/thumbnail.jp