Information Centric Networking in the IoT: Experiments with NDN in the Wild

This paper explores the feasibility, advantages, and challenges of an ICN-based approach in the Internet of Things. We report on the first NDN experiments in a life-size IoT deployment, spread over tens of rooms on several floors of a building. Based on the insights gained with these experiments, the paper analyses the shortcomings of CCN applied to IoT. Several interoperable CCN enhancements are then proposed and evaluated. We significantly decreased control traffic (i.e., interest messages) and leverage data path and caching to match IoT requirements in terms of energy and bandwidth constraints. Our optimizations increase content availability in case of IoT nodes with intermittent activity. This paper also provides the first experimental comparison of CCN with the common IoT standards 6LoWPAN/RPL/UDP.Comment: 10 pages, 10 figures and tables, ACM ICN-2014 conferenc

A Case for Time Slotted Channel Hopping for ICN in the IoT

Recent proposals to simplify the operation of the IoT include the use of Information Centric Networking (ICN) paradigms. While this is promising, several challenges remain. In this paper, our core contributions (a) leverage ICN communication patterns to dynamically optimize the use of TSCH (Time Slotted Channel Hopping), a wireless link layer technology increasingly popular in the IoT, and (b) make IoT-style routing adaptive to names, resources, and traffic patterns throughout the network--both without cross-layering. Through a series of experiments on the FIT IoT-LAB interconnecting typical IoT hardware, we find that our approach is fully robust against wireless interference, and almost halves the energy consumed for transmission when compared to CSMA. Most importantly, our adaptive scheduling prevents the time-slotted MAC layer from sacrificing throughput and delay

Connecting the World of Embedded Mobiles: The RIOT Approach to Ubiquitous Networking for the Internet of Things

The Internet of Things (IoT) is rapidly evolving based on low-power compliant protocol standards that extend the Internet into the embedded world. Pioneering implementations have proven it is feasible to inter-network very constrained devices, but had to rely on peculiar cross-layered designs and offer a minimalistic set of features. In the long run, however, professional use and massive deployment of IoT devices require full-featured, cleanly composed, and flexible network stacks. This paper introduces the networking architecture that turns RIOT into a powerful IoT system, to enable low-power wireless scenarios. RIOT networking offers (i) a modular architecture with generic interfaces for plugging in drivers, protocols, or entire stacks, (ii) support for multiple heterogeneous interfaces and stacks that can concurrently operate, and (iii) GNRC, its cleanly layered, recursively composed default network stack. We contribute an in-depth analysis of the communication performance and resource efficiency of RIOT, both on a micro-benchmarking level as well as by comparing IoT communication across different platforms. Our findings show that, though it is based on significantly different design trade-offs, the networking subsystem of RIOT achieves a performance equivalent to that of Contiki and TinyOS, the two operating systems which pioneered IoT software platforms

Constraints of FL Motif on the Targeting and Function of Sodium-Bicarbonate Cotransporter 1

A C-terminal dihydrophobic FL motif plays a vital role in the basolateral targeting of sodium bicarbonate cotransporter 1. To further characterize the role of dihydrophobic FL motif, 1). the FL motif in wild type (PFLS) was reversed to LF (PLFS), 2). the FL motif (PFLS) was shifted upstream (FLPS), and 3). the FL motif (PFLS) was shifted downstream (PSFL). The wild type (PFLS) and its mutant (PLFS) were exclusively expressed on the basolateral membrane by con-focal microscopy, however, the mutant (FLPS) and (PSFL) were predominantly mistargeted to the apical membrane and the cytoplasm, respectively. Functional studies showed that the mutant (PSFL) displayed a remarkably reduced current (p value<0.05 vs wild type). The mutant (PSFL) displayed a more reduced membrane surface expression than the wild type and was co-localized with ER marker. The protein sequence spanning FL motif in kNBC1 C-terminal cytoplasmic tail shows a helical structure, mutants (PLFS) and (PSFL) reduce a-helical contents by circular dichroism study. Reversed FL isn't a constraint for basolateral targeting, but shifting it upstream and downstream are ones

Modular automated solid phase synthesis of dermatan sulfate oligosaccharides

Dermatan sulfates are glycosaminoglycan polysaccharides that serve a multitude of biological roles as part of the extracellular matrix. Orthogonally protected D-galactosamine and L-iduronic acid building blocks and a photo- cleavable linker are instrumental for the automated synthesis of dermatan sulfate oligosaccharides. Conjugation-ready oligosaccharides were obtained in good yield

Shear-Flow Driven Current Filamentation: Two-Dimensional Magnetohydrodynamic Simulations

The process of current filamentation in permanently externally driven, initially globally ideal plasmas is investigated by means of two-dimensional Magnetohydrodynamic (MHD)-simulations. This situation is typical for astrophysical systems like jets, the interstellar and intergalactic medium where the dynamics is dominated by external forces. Two different cases are studied. In one case, the system is ideal permanently and dissipative processes are excluded. In the second case, a system with a current density dependent resistivity is considered. This resistivity is switched on self-consistently in current filaments and allows for local dissipation due to magnetic reconnection. Thus one finds tearing of current filaments and, besides, merging of filaments due to coalescence instabilities. Energy input and dissipation finally balance each other and the system reaches a state of constant magnetic energy in time.Comment: 32 Pages, 13 Figures. accepted, to appear in Physics of Plasmas (049012

C. elegans maximum velocity correlates with healthspan and is maintained in worms with an insulin receptor mutation

Ageing is marked by physical decline. Caenorhabditis elegans is a valuable model for identifying genetic regulatory mechanisms of ageing and longevity. Here we report a simple method to assess C. elegans' maximum physical ability based on the worms' maximum movement velocity. We show maximum velocity declines with age, correlates well with longevity, accurately reports movement ability and, if measured in mid-adulthood, is predictive of maximal lifespan. Contrary to recent findings, we observe that maximum velocity of worm with mutations in daf-2(e1370) insulin/IGF-1 signalling scales with lifespan. Because of increased odorant receptor expression, daf-2(e1370) mutants prefer food over exploration, causing previous on-food motility assays to underestimate movement ability and, thus, worm health. Finally, a disease-burden analysis of published data reveals that the daf-2(e1370) mutation improves quality of life, and therefore combines lifespan extension with various signs of an increased healthspan.114232Ysciescopu

A Procedure for Determination of Degradation Acceptance Criteria for Structures and Passive Components in Nuclear Power Plants

The Korea Atomic Energy Research Institute (KAERI) has been collaborating with Brookhaven National Laboratory since 2007 to develop a realistic seismic risk evaluation system which includes the consideration of aging of structures and components in nuclear power plants (NPPs). This collaboration program aims at providing technical support to a five-year KAERI research project, which includes three specific areas that are essential to seismic probabilistic risk assessment: (1) probabilistic seismic hazard analysis, (2) seismic fragility analysis including the effects of aging, and (3) a plant seismic risk analysis. The understanding and assessment of age-related degradations of structures, systems, and components and their impact on plant safety is the major goal of this KAERI-BNL collaboration. Four annual reports have been published before this report as a result of the collaboration research