Featured Piece

This year the General Editors continued the tradition started last year by creating a feature piece to show our appreciation for the History Department. We selected four professors from the faculty to answer a question about history: what figure/event/idea inspires your interest in history? Reading their responses helped give us insight into the thoughts of these brilliant minds and further help us understand their passion for the subject we all share a common love and interest in. We hope that you enjoy reading their responses as much as we did. The four members of the faculty we spoke with are Dr. Abou Bamba, Dr. William Bowman, Dr. David Hadley, and Magdalena Sánchez

Comparison of Routable Control System Security Approaches

This document is an supplement to the 'Secure and Efficient Routable Control Systems.' It addressed security in routable control system communication. The control system environment that monitors and manages the power grid historically has utilized serial communication mechanisms. Leased-line serial communication environments operating at 1200 to 9600 baud rates are common. However, recent trends show that communication media such as fiber, optical carrier 3 (OC-3) speeds, mesh-based high-speed wireless, and the Internet are becoming the media of choice. In addition, a dichotomy has developed between the electrical transmission and distribution environments, with more modern communication infrastructures deployed by transmission utilities. The preceding diagram represents a typical control system. The Communication Links cloud supports all of the communication mechanisms a utility might deploy between the control center and devices in the field. Current methodologies used for security implementations are primarily led by single vendors or standards bodies. However, these entities tend to focus on individual protocols. The result is an environment that contains a mixture of security solutions that may only address some communication protocols at an increasing operational burden for the utility. A single approach is needed that meets operational requirements, is simple to operate, and provides the necessary level of security for all control system communication. The solution should be application independent (e.g., Distributed Network Protocol/Internet Protocol [DNP/IP], International Electrotechnical Commission [IEC] C37.118, Object Linking and Embedding for Process Control [OPC], etc.) and focus on the transport layer. In an ideal setting, a well-designed suite of standards for control system communication will be used for vendor implementation and compliance testing. An expected outcome of this effort is an international standard

Inference of disease associations with unmeasured genetic variants by combining results from genome-wide association studies with linkage disequilibrium patterns in a reference data set

Results from whole-genome association studies of many common diseases are now available. Increasingly, these are being incorporated into meta-analyses to increase the power to detect weak associations with measured single-nucleotide polymorphisms (SNPs). Imputation of genotypes at unmeasured loci has been widely applied using patterns of linkage disequilibrium (LD) observed in the HapMap panels, but there is a need for alternative methods that can utilize the pooled effect estimates from meta-analyses and explore possible associations with SNPs and haplotypes that are not included in HapMap

Secure and Efficient Routable Control Systems

This document provides the methods to secure routable control system communication in the electric sector. The approach of this document yields a long-term vision for a future of secure communication, while also providing near term steps and a roadmap. The requirements for the future secure control system environment were spelled out to provide a final target. Additionally a survey and evaluation of current protocols was used to determine if any existing technology could achieve this goal. In the end a four-step path was described that brought about increasing requirement completion and culminates in the realization of the long term vision

Learning needs analysis to guide teaching evidence-based medicine: knowledge and beliefs amongst trainees from various specialities

<p>Abstract</p> <p>Background</p> <p>We undertook a needs assessment exercise using questionnaire survey of junior doctors' knowledge and beliefs concerning evidence-based medicine (EBM) and critical literature appraisal, as this is a core competence in postgraduate medical education.</p> <p>Methods</p> <p>We surveyed 317 junior doctors in various specialities in the UK West Midlands Deanery. Using validated questionnaires we compared the needs of different trainee groups. Results overall were internally consistent (Cronbach's alpha 0.929).</p> <p>Results</p> <p>Respondents' generally felt that they had poor training in EBM (Mean score 2.2, possible range 1 – 6) and that they needed more education (Mean score 5.3, possible range 1–6). Male trainees felt more confident at evaluating statistical tests than females (p = 0.002). Female trainees considered patient choice above the evidence more often than males (p = 0.038). Trainees from surgical speciality felt more confident at assessing research evidence (p = 0.009) whereas those from medical speciality felt more confident at evaluating statistical tests (p = 0.038) than other specialities. However, non-surgical specialities tended to believe that EBM had little impact on practice (p = 0.029). Respondents who had been qualified for 11 years or over felt overall more confident in their knowledge relating to EBM than those who had been qualified less than 10 years. In particular, they felt more confident at being able to assess study designs (p = < 0.001) and the general worth of research papers (p = < 0.001). Trainees with prior research experience were less likely to find original work confusing (p = 0.003) and felt more confident that they can assess research evidence (p = < 0.001) compared to those without previous research experience. Trainees without previous research experience felt that clinical judgement was more important than evidence (p = < 0.001).</p> <p>Conclusion</p> <p>There is a perceived deficit in postgraduate doctors' EBM knowledge and critical appraisal skills. Learning needs vary according to gender, place of basic medical qualification, time since graduation, prior research experience and speciality. EBM training curricular development should take into account the findings of our needs assessment study.</p

The bashful and the boastful : prestigious leaders and social change in Mesolithic Societies

The creation and maintenance of influential leaders and authorities is one of the key themes of archaeological and historical enquiry. However the social dynamics of authorities and leaders in the Mesolithic remains a largely unexplored area of study. The role and influence of authorities can be remarkably different in different situations yet they exist in all societies and in almost all social contexts from playgrounds to parliaments. Here we explore the literature on the dynamics of authority creation, maintenance and contestation in egalitarian societies, and discuss the implications for our interpretation and understanding of the formation of authorities and leaders and changing social relationships within the Mesolithic

Soil Respiration in a Northeastern US Temperate Forest: A 22-Year Synthesis

To better understand how forest management, phenology, vegetation type, and actual and simulated climatic change affect seasonal and inter-annual variations in soil respiration (R$_{s}$), we analyzed more than 100,000 individual measurements of soil respiration from 23 studies conducted over 22 years at the Harvard Forest in Petersham, Massachusetts, USA. We also used 24 site-years of eddy-covariance measurements from two Harvard Forest sites to examine the relationship between soil and ecosystem respiration (R$_{e}$). R$_{s}$ was highly variable at all spatial (respiration collar to forest stand) and temporal (minutes to years) scales of measurement. The response of R$_{s}$ to experimental manipulations mimicking aspects of global change or aimed at partitioning R$_{s}$ into component fluxes ranged from −70% to +52%. The response appears to arise from variations in substrate availability induced by changes in the size of soil C pools and of belowground C fluxes or in environmental conditions. In some cases (e.g., logging, warming), the effect of experimental manipulations on R$_{s}$ was transient, but in other cases the time series were not long enough to rule out long-term changes in respiration rates. Inter-annual variations in weather and phenology induced variation among annual R$_{s}$ estimates of a magnitude similar to that of other drivers of global change (i.e., invasive insects, forest management practices, N deposition). At both eddy-covariance sites, aboveground respiration dominated R$_{e}$ early in the growing season, whereas belowground respiration dominated later. Unusual aboveground respiration patterns—high apparent rates of respiration during winter and very low rates in mid-to-late summer—at the Environmental Measurement Site suggest either bias in R$_{s}$ and R$_{e}$ estimates caused by differences in the spatial scale of processes influencing fluxes, or that additional research on the hard-to-measure fluxes (e.g., wintertime R$_{s}$, unaccounted losses of CO$_{2}$ from eddy covariance sites), daytime and nighttime canopy respiration and its impacts on estimates of R$_{e}$, and independent measurements of flux partitioning (e.g., aboveground plant respiration, isotopic partitioning) may yield insight into the unusually high and low fluxes. Overall, however, this data-rich analysis identifies important seasonal and experimental variations in R$_{s}$ and R$_{e}$ and in the partitioning of R$_{e}$ above- vs. belowground.Organismic and Evolutionary Biolog

Search for New Physics Using Quaero: A General Interface to D0 Event Data

We describe Quaero, a method that i) enables the automatic optimization of searches for physics beyond the standard model, and ii) provides a mechanism for making high energy collider data generally available. We apply Quaero to searches for standard model WW, ZZ, and ttbar production, and to searches for these objects produced through a new heavy resonance. Through this interface, we make three data sets collected by the D0 experiment at sqrt(s)=1.8 TeV publicly available.Comment: 7 pages, submitted to Physical Review Letter