Spin Hall effect due to intersubband-induced spin-orbit interaction in symmetric quantum wells

We investigate the intrinsic spin Hall effect in two-dimensional electron gases in quantum wells with two subbands, where a new intersubband-induced spin-orbit coupling is operative. The bulk spin Hall conductivity $\sigma^z_{xy}$ is calculated in the ballistic limit within the standard Kubo formalism in the presence of a magnetic field $B$ and is found to remain finite in the B=0 limit, as long as only the lowest subband is occupied. Our calculated $\sigma^z_{xy}$ exhibits a nonmonotonic behavior and can change its sign as the Fermi energy (the carrier areal density $n_{2D}$) is varied between the subband edges. We determine the magnitude of $\sigma^z_{xy}$ for realistic InSb quantum wells by performing a self-consistent calculation of the intersubband-induced spin-orbit coupling.Comment: 7 pages, 3 figure

Persistent Skyrmion Lattice of Noninteracting Electrons with Spin-Orbit Coupling

A persistent spin helix (PSH) is a robust helical spin-density pattern arising in disordered 2D electron gases with Rashba $\alpha$ and Dresselhaus $\beta$ spin-orbit (SO) tuned couplings, i.e., $\alpha=\pm\beta$. Here we investigate the emergence of a Persistent Skyrmion Lattice (PSL) resulting from the coherent superposition of PSHs along orthogonal directions -- crossed PSHs -- in wells with two occupied subbands $\nu=1,2$. For realistic GaAs wells we show that the Rashba $\alpha_\nu$ and Dresselhaus $\beta_\nu$ couplings can be simultaneously tuned to equal strengths but opposite signs, e.g., $\alpha_1= \beta_1$ and $\alpha_2=-\beta_2$. In this regime and away from band anticrossings, our {\it non-interacting} electron gas sustains a topologically non-trivial skyrmion-lattice spin-density excitation, which inherits the robustness against spin-independent disorder and interactions from its underlying crossed PSHs. We find that the spin relaxation rate due to the interband SO coupling is comparable to that of the cubic Dresselhaus term as a mechanism of the PSL decay. Near anticrossings, the interband-induced spin mixing leads to unusual spin textures along the energy contours beyond those of the Rahsba-Dresselhaus bands. Our PSL opens up the unique possibility of observing topological phenomena, e.g., topological and skyrmion Hall effects, in ordinary GaAs wells with non-interacting electrons.Comment: 5 pages, 2 figures; changed the presentation and added supplemental material (17 pages, 1 figure

On the Steady Nature of Line-Driven Disk Winds: Application to Cataclysmic Variables

We apply the semi-analytical analysis of the steady nature of line-driven winds presented in two earlier papers to disk winds driven by the flux distribution of a standard Shakura & Sunyaev (1973) disk for typical cataclysmic variable (CV) parameters. We find that the wind critical point tends to be closer to the disk surface towards the inner disk regions. Our main conclusion, however, is that a line-driven wind, arising from a steady disk flux distribution of a standard Shakura-Sunyaev disk capable of locally supplying the corresponding mass flow, is steady. These results confirm the findings of an earlier paper that studied "simple" flux distributions that are more readily analyzable than those presented here. These results are consistent with the steady velocity nature of outflows observationally inferred for both CVs and quasi-stellar objects (QSOs). We find good agreement with the 2.5D CV disk wind models of Pereyra and collaborators. These results suggest that the likely scenario to account for the wind outflows commonly observed in CVs is the line-driven accretion disk wind scenario, as suggested early-on by Cordova & Mason (1982). For QSOs, these results show that the line-driven accretion disk wind continues to be a promising scenario to account for the outflows detected in broad absorption line (BAL) QSOs, as suggested early-on by Turnshek (1984), and analyzed in detail by Murray et al. (1995).Comment: 35 pages, 20 figure

APRIL: Active Preference-learning based Reinforcement Learning

This paper focuses on reinforcement learning (RL) with limited prior knowledge. In the domain of swarm robotics for instance, the expert can hardly design a reward function or demonstrate the target behavior, forbidding the use of both standard RL and inverse reinforcement learning. Although with a limited expertise, the human expert is still often able to emit preferences and rank the agent demonstrations. Earlier work has presented an iterative preference-based RL framework: expert preferences are exploited to learn an approximate policy return, thus enabling the agent to achieve direct policy search. Iteratively, the agent selects a new candidate policy and demonstrates it; the expert ranks the new demonstration comparatively to the previous best one; the expert's ranking feedback enables the agent to refine the approximate policy return, and the process is iterated. In this paper, preference-based reinforcement learning is combined with active ranking in order to decrease the number of ranking queries to the expert needed to yield a satisfactory policy. Experiments on the mountain car and the cancer treatment testbeds witness that a couple of dozen rankings enable to learn a competent policy

Restriction fragment mass polymorphism (RFMP) analysis based on MALDI-TOF mass spectrometry for detecting antiretroviral resistance in HIV-1 infected patients

AbstractViral genotype assessment is important for effective clinical management of HIV-1 infected patients, especially when access and/or adherence to antiretroviral treatment is reduced. In this study, we describe development of a matrix-assisted laser desorption/ionization-time of flight mass spectrometry-based viral genotyping assay, termed restriction fragment mass polymorphism (RFMP). This assay is suitable for sensitive, specific and high-throughput detection of multiple drug-resistant HIV-1 variants. One hundred serum samples from 60 HIV-1-infected patients previously exposed to nucleoside reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs) and protease inhibitors (PIs) were analysed for the presence of drug-resistant viruses using the RFMP and direct sequencing assays. Probit analysis predicted a detection limit of 223.02 copies/mL for the RFMP assay and 1268.11 copies/mL for the direct sequencing assays using HIV-1 RNA Positive Quality Control Series. The concordance rates between the RFMP and direct sequencing assays for the examined codons were 97% (K65R), 97% (T69Ins/D), 97% (L74VI), 97% (K103N), 96% (V106AM), 97% (Q151M), 97% (Y181C), 97% (M184VI) and 94% (T215YF) in the reverse transcriptase coding region, and 100% (D30N), 100% (M46I), 100% (G48V), 100% (I50V), 100% (I54LS), 99% (V82A), 99% (I84V) and 100% (L90M) in the protease coding region. Defined mixtures were consistently and accurately identified by RFMP at 5% relative concentration of mutant to wild-type virus while at 20% or greater by direct sequencing. The RFMP assay based on mass spectrometry proved to be sensitive, accurate and reliable for monitoring the emergence and early detection of HIV-1 genotypic variants that lead to drug resistance

Study of electron anti-neutrinos associated with gamma-ray bursts using KamLAND

We search for electron anti-neutrinos ($\overline{\nu}_e$) from long and short-duration gamma-ray bursts~(GRBs) using data taken by the KamLAND detector from August 2002 to June 2013. No statistically significant excess over the background level is found. We place the tightest upper limits on $\overline{\nu}_e$ fluence from GRBs below 7 MeV and place first constraints on the relation between $\overline{\nu}_e$ luminosity and effective temperature.Comment: 16 pages and 5 figure