1,673 research outputs found
Analysis and Functional Annotation of Expressed Sequence Tags from the Asian Longhorned Beetle, Anoplophora glabripennis
The Asian longhorned beetle, Anoplophora glabripennis (Motschulsky) (Coleoptera: Cerambycidae), is one of the most economically and ecologically devastating forest insects to invade North America in recent years. Despite its substantial impact, limited effort has been expended to define the genetic and molecular make-up of this species. Considering the significant role played by late-stadia larvae in host tree decimation, a small-scale EST sequencing project was done using a cDNA library constructed from 5th -instar A. glabripennis. The resultant dataset consisted of 599 high quality ESTs that, upon assembly, yielded 381 potentially unique transcripts. Each of these transcripts was catalogued as to putative molecular function, biological process, and associated cellular component according to the Gene Ontology classification system. Using this annotated dataset, a subset of assembled sequences was identified that are putatively associated with A. glabnpennis development and metamorphosis. This work will contribute to understanding of the diverse molecular mechanisms that underlie coleopteran morphogenesis and enable the future development of novel control strategies for management of this insect pest
The LQG -- String: Loop Quantum Gravity Quantization of String Theory I. Flat Target Space
We combine I. background independent Loop Quantum Gravity (LQG) quantization
techniques, II. the mathematically rigorous framework of Algebraic Quantum
Field Theory (AQFT) and III. the theory of integrable systems resulting in the
invariant Pohlmeyer Charges in order to set up the general representation
theory (superselection theory) for the closed bosonic quantum string on flat
target space. While we do not solve the, expectedly, rich representation theory
completely, we present a, to the best of our knowledge new, non -- trivial
solution to the representation problem. This solution exists 1. for any target
space dimension, 2. for Minkowski signature of the target space, 3. without
tachyons, 4. manifestly ghost -- free (no negative norm states), 5. without
fixing a worldsheet or target space gauge, 6. without (Virasoro) anomalies
(zero central charge), 7. while preserving manifest target space Poincar\'e
invariance and 8. without picking up UV divergences. The existence of this
stable solution is exciting because it raises the hope that among all the
solutions to the representation problem (including fermionic degrees of
freedom) we find stable, phenomenologically acceptable ones in lower
dimensional target spaces, possibly without supersymmetry, that are much
simpler than the solutions that arise via compactification of the standard Fock
representation of the string. Moreover, these new representations could solve
some of the major puzzles of string theory such as the cosmological constant
problem. The solution presented in this paper exploits the flatness of the
target space in several important ways. In a companion paper we treat the more
complicated case of curved target spaces.Comment: 46 p., LaTex2e, no figure
Instanton Induced Neutrino Majorana Masses in CFT Orientifolds with MSSM-like spectra
Recently it has been shown that string instanton effects may give rise to
neutrino Majorana masses in certain classes of semi-realistic string
compactifications. In this paper we make a systematic search for supersymmetric
MSSM-like Type II Gepner orientifold constructions admitting boundary states
associated with instantons giving rise to neutrino Majorana masses and other L-
and/or B-violating operators. We analyze the zero mode structure of D-brane
instantons on general type II orientifold compactifications, and show that only
instantons with O(1) symmetry can have just the two zero modes required to
contribute to the 4d superpotential. We however discuss how the addition of
fluxes and/or possible non-perturbative extensions of the orientifold
compactifications would allow also instantons with and U(1) symmetries
to generate such superpotentials. In the context of Gepner orientifolds with
MSSM-like spectra, we find no models with O(1) instantons with just the
required zero modes to generate a neutrino mass superpotential. On the other
hand we find a number of models in one particular orientifold of the Gepner
model with instantons with a few extra uncharged
non-chiral zero modes which could be easily lifted by the mentioned effects. A
few more orientifold examples are also found under less stringent constraints
on the zero modes. This class of instantons have the interesting
property that R-parity conservation is automatic and the flavour structure of
the neutrino Majorana mass matrices has a simple factorized form.Comment: 68 pages, 2 figures; v2. typos corrected, refs adde
Ruthenacycles and Iridacycles as Catalysts for Asymmetric Transfer Hydrogenation and Racemisation
Ruthenacycles, which are easily prepared in a single step by reaction between enantiopure aromatic amines and [Ru(arene)Cl2]2 in the presence of NaOH and KPF6, are very good asymmetric transfer hydrogenation catalysts. A range of aromatic ketones were reduced using isopropanol in good yields with eeâs up to 98%. Iridacycles, which are prepared in similar fashion from [IrCp*Cl2]2 are excellent catalysts for the racemisation of secondary alcohols and chlorohydrins at room temperature. This allowed the development of a new dynamic kinetic resolution of chlorohydrins to the enantiopure epoxides in up to 90% yield and 98% enantiomeric excess (ee) using a mutant of the enzyme Haloalcohol dehalogenase C and an iridacycle as racemisation catalyst.
The proton radius puzzle
High-precision measurements of the proton radius from laser spectroscopy of
muonic hydrogen demonstrated up to six standard deviations smaller values than
obtained from electron-proton scattering and hydrogen spectroscopy. The status
of this discrepancy, which is known as the proton radius puzzle will be
discussed in this paper, complemented with the new insights obtained from
spectroscopy of muonic deuterium.Comment: Moriond 2017 conference, 8 pages, 4 figure
Brane Inflation and Cosmic String Tension in Superstring Theory
In a simple reanalysis of the KKLMMT scenario, we argue that the slow roll
condition in the D3-anti-D3-brane inflationary scenario in superstring theory
requires no more than a moderate tuning. The cosmic string tension is very
sensitive to the conformal coupling: with less fine-tuning, the cosmic string
tension (as well as the ratio of tensor to scalar perturbation mode) increases
rapidly and can easily saturate the present observational bound. In a
multi-throat brane inflationary scenario, this feature substantially improves
the chance of detecting and measuring the properties of the cosmic strings as a
window to the superstring theory and our pre-inflationary universe.Comment: Combined bounds from WMAP and SDSS Lyman alpha experiments are added
for analysis, changes are added to the tabl
Outcomes of âAnterior Versus Posterior Divisional Branches of the Hypogastric Artery as Distal Landing Zone for Iliac Branch Devicesâ: The International Multicentric R3OYAL Registry
Objective: The aim of this multicentric registry was to assess the outcomes of âanteRior versus posteRior divisional bRanches Of the hYpogastric artery as distAl landing zone for iLiac branch devices (R3OYAL).â Methods: The main exposure of interest for the purpose of this study was the internal iliac artery (IIA) divisional branch (anterior vs posterior) that was used as distal landing zone. Early endpoints included technical success and adverse events. Late endpoints included survival, primary/secondary IIA patency, and IIA branch instability. Results: A total of 171 patients were included in the study, of which 50 received bilateral implantation of iliac branch devices (IBDs). This resulted in a total of 221 incorporated IIAs included in the final analysis, of which 40 were anterior divisional branches and 181 were posterior divisional branches. Technical success was high in both groups (anterior division: 98% vs posterior division: 100%, P =.18). Occurrence of any adverse event was noted in 14% of patients in both groups (P = 1.0). The overall rate of freedom from the composite IBD branch instability did not show significant differences between patients receiving distal landing in the anterior or posterior division of the IIA at 3 years (79% vs 87%, log-rank test =.215). The 3-year estimates of IBD patency were significantly lower in patients who received distal landing in the anterior divisional branch than those who received distal landing in the posterior divisional branch (primary patency: 81% vs 96%, log-rank test =.009; secondary patency: 81% vs 97%, log-rank test <.001). Conclusions: The use of the anterior or posterior divisional branches of the IIA as distal landing zone for IBD implantation shows comparable profiles in terms of immediate technical success, perioperative safety, and side-branch instability up to 3 years. However, IBD patency at 3 years was higher when the distal landing zone was achieved within the posterior divisional branch of the IIA. Clinical Impact: The results from this large multicentric registry confirm that use of the anterior or posterior divisional branches of the internal iliac artery (IIA) as distal landing zone for implantation of iliac branch devices (IBD) shows comparable profiles of safety and feasibility, thereby allowing to extend the indications for endovascular repair of aorto-iliac aneurysms to cases with unsuitable anatomy within the IIA main trunk. Although mid-term rates of device durability and branch instability seem to be similar, the rates of primary and secondary IBD patency at three years was favored when the distal landing zone was achieved in the posterior divisional branch of the IIA
Professionalism, Golf Coaching and a Master of Science Degree: A commentary
As a point of reference I congratulate Simon Jenkins on tackling the issue of professionalism in coaching. As he points out coaching is not a profession, but this does not mean that coaching would not benefit from going through a professionalization process. As things stand I find that the stimulus article unpacks some critically important issues of professionalism, broadly within the context of golf coaching. However, I am not sure enough is made of understanding what professional (golf) coaching actually is nor how the development of a professional golf coach can be facilitated by a Master of Science Degree (M.Sc.). I will focus my commentary on these two issues
Constraints on Brane Inflation and Cosmic Strings
By considering simple, but representative, models of brane inflation from a
single brane-antibrane pair in the slow roll regime, we provide constraints on
the parameters of the theory imposed by measurements of the CMB anisotropies by
WMAP including a cosmic string component. We find that inclusion of the string
component is critical in constraining parameters. In the most general model
studied, which includes an inflaton mass term, as well as the brane-antibrane
attraction, values n_s < 1.02 are compatible with the data at 95 % confidence
level. We are also able to constrain the volume of internal manifold (modulo
factors dependent on the warp factor) and the value of the inflaton field to be
less than 0.66M_P at horizon exit. We also investigate models with a mass term.
These observational considerations suggest that such models have r < 2*10^-5,
which can only be circumvented in the fast roll regime, or by increasing the
number of antibranes. Such a value of r would not be detectable in CMB
polarization experiment likely in the near future, but the B-mode signal from
the cosmic strings could be detectable. We present forecasts of what a similar
analysis using PLANCK data would yield and find that it should be possible to
rule out G\mu > 6.5*10^-8 using just the TT, TE and EE power spectra.Comment: 11 pages, 3 figures, revtex4, typos corrected, references adde
Perturbing gauge/gravity duals by a Romans mass
We show how to produce algorithmically gravity solutions in massive IIA (as
infinitesimal first order perturbations in the Romans mass parameter) dual to
assigned conformal field theories. We illustrate the procedure on a family of
Chern--Simons--matter conformal field theories that we recently obtained from
the N=6 theory by waiving the condition that the levels sum up to zero.Comment: 30 page
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