Strange two-baryon interactions using chiral effective field theory

We have constructed the leading order strangeness S=-1,-2 baryon-baryon potential in a chiral effective field theory approach. The chiral potential consists of one-pseudoscalar-meson exchanges and non-derivative four-baryon contact terms. The potential, derived using SU(3)_f symmetry constraints, contains six independent low-energy coefficients. We have solved a regularized Lippmann-Schwinger equation and achieved a good description of the available scattering data. Furthermore a correctly bound hypertriton has been obtained.Comment: 3 pages, 2 PostScript figures, talk to appear in the proceedings of the "20th European Conference on Few-Body Problems in Physics (EFB20), Pisa, Italy, 10-14 September 2007

Determination of the characteristic directions of lossless linear optical elements

We show that the problem of finding the primary and secondary characteristic directions of a linear lossless optical element can be reformulated in terms of an eigenvalue problem related to the unimodular factor of the transfer matrix of the optical device. This formulation makes any actual computation of the characteristic directions amenable to pre-implemented numerical routines, thereby facilitating the decomposition of the transfer matrix into equivalent linear retarders and rotators according to the related Poincare equivalence theorem. The method is expected to be useful whenever the inverse problem of reconstruction of the internal state of a transparent medium from optical data obtained by tomographical methods is an issue.Comment: Replaced with extended version as published in JM

Measurements of scattering observables for the pdpd break-up reaction

High-precision measurements of the scattering observables such as cross sections and analyzing powers for the proton-deuteron elastic and break-up reactions have been performed at KVI in the last two decades and elsewhere to investigate various aspects of the three-nucleon force (3NF) effects simultaneously. In 2006 an experiment was performed to study these effects in $\vec{p}+d$ break-up reaction at 135 MeV with the detection system, Big Instrument for Nuclear polarization Analysis, BINA. BINA covers almost the entire kinematical phase space of the break-up reaction. The results are interpreted with the help of state-of-the-art Faddeev calculations and are partly presented in this contribution.Comment: Proceedings of 19th International IUPAP Conference on Few-Body Problems in Physics, Bonn University, 31.08 - 05.09.2009, Bonn, GERMAN

Three-Body Halo States in Effective Field Theory: Renormalization and Three-Body Interactions in the Helium-6 System

In this paper we study the renormalization of Halo effective field theory applied to the Helium-6 halo nucleus seen as an alpha-neutron-neutron three-body state. We include the 0(+) dineutron channel together with both the 3/2(-) and 1/2(-) neutron-alpha channels into the field theory and study all of the six lowest-order three-body interactions that are present. Furthermore, we discuss three different prescriptions to handle the unphysical poles in the P-wave two-body sector. In the simpler field theory without the 1/2(-) channel present we find that the bound-state spectrum of the field theory is renormalized by the inclusion of a single three-body interaction. However, in the field theory with both the 3/2(-) and 1/2(-) included, the system can not be renormalized by only one three-body operator

Universality in Few-Body Systems

Low-energy universality in atomic few-body systems as a result of a large two-body scattering length has gained a lot of attention recently. Here, I discuss recent progress in describing the three-body recombination of cold atoms in terms of a finite set of universal scaling functions and review results for the recombination length of cesium-133 atoms obtained with these functions. Furthermore, I will consider the inclusion of effective range corrections and the relevance for further calculations in atomic and nuclear physics.Comment: Plenary talk at 20th European Conference on Few-Body Problems in Physics (EFB 20), Pisa, Italy, 10-14 Sep 2007, FBS style, 2 figue

Strangeness in the nucleon and the ratio of proton-to-neutron neutrino-induced quasi-elastic yield

The electroweak form factors of the nucleon as obtained within a three flavor pseudoscalar vector meson soliton model are employed to predict the ratio of the proton and neutron yields from $^{12}C$, which are induced by quasi-elastic neutrino reactions. These predictions are found to vary only moderately in the parameter space allowed by the model. The antineutrino flux of the up-coming experiment determining this ratio was previously overestimated. The corresponding correction is shown to have only a small effect on the predicted ratio. However, it is found that the experimental result for the ratio crucially depends on an accurate measurement of the energy of the knocked out nucleon.Comment: 17 pages, LaTeX, 2 tables, 4 figures, Discussion on shape of strange form factors added, Z. Phys. A, to be publishe

Logical Analysis of Data (LAD) model for the early diagnosis of acute ischemic stroke

<p>Abstract</p> <p>Background</p> <p>Strokes are a leading cause of morbidity and the first cause of adult disability in the United States. Currently, no biomarkers are being used clinically to diagnose acute ischemic stroke. A diagnostic test using a blood sample from a patient would potentially be beneficial in treating the disease.</p> <p>Results</p> <p>A classification approach is described for differentiating between proteomic samples of stroke patients and controls, and a second novel predictive model is developed for predicting the severity of stroke as measured by the National Institutes of Health Stroke Scale (NIHSS). The models were constructed by applying the Logical Analysis of Data (LAD) methodology to the mass peak profiles of 48 stroke patients and 32 controls. The classification model was shown to have an accuracy of 75% when tested on an independent validation set of 35 stroke patients and 25 controls, while the predictive model exhibited superior performance when compared to alternative algorithms. In spite of their high accuracy, both models are extremely simple and were developed using a common set consisting of only 3 peaks.</p> <p>Conclusion</p> <p>We have successfully identified 3 biomarkers that can detect ischemic stroke with an accuracy of 75%. The performance of the classification model on the validation set and on cross-validation does not deteriorate significantly when compared to that on the training set, indicating the robustness of the model. As in the case of the LAD classification model, the results of the predictive model validate the function constructed on our support-set for approximating the severity scores of stroke patients. The correlation and root mean absolute error of the LAD predictive model are consistently superior to those of the other algorithms used (Support vector machines, C4.5 decision trees, Logistic regression and Multilayer perceptron).</p

Balancing hydrogen adsorption/desorption by orbital modulation for efficient hydrogen evolution catalysis

Hydrogen adsorption/desorption behavior plays a key role in hydrogen evolution reaction (HER) catalysis. The HER reaction rate is a trade-off between hydrogen adsorption and desorption on the catalyst surface. Herein, we report the rational balancing of hydrogen adsorption/desorption by orbital modulation using introduced environmental electronegative carbon/nitrogen (C/N) atoms. Theoretical calculations reveal that the empty d orbitals of iridium (Ir) sites can be reduced by interactions between the environmental electronegative C/N and Ir atoms. This balances the hydrogen adsorption/ desorption around the Ir sites, accelerating the related HER process. Remarkably, by anchoring a small amount of Ir nanoparticles (7.16 wt%) in nitrogenated carbon matrixes, the resulting catalyst exhibits significantly enhanced HER performance. This includs the smallest reported overpotential at 10 mA cm(-2) (4.5 mV), the highest mass activity at 10 mV (1.12 A mg(Ir)(-1)) and turnover frequency at 25 mV (4.21 H2 s(-1)) by far, outperforming Ir nanoparticles and commercial Pt/C

NF-κB: a new player in angiostatic therapy

Angiogenesis is considered a promising target in the treatment of cancer. Most of the angiogenesis inhibitors in late-stage clinical testing or approved for the treatment of cancer act indirectly on endothelial cells. They either neutralize angiogenic growth factors from the circulation or block the signaling pathways activated by these growth factors. Another group of angiogenesis inhibitors are the direct angiostatic compounds. These agents have a direct effect on the endothelium, affecting cellular regulatory pathways, independently of the tumor cells. The reason that this category of agents is lagging behind regarding their translation to the clinic may be the lack of sufficient knowledge on the mechanism of action of these compounds. The transcription factor NF-κB has been recently connected with multiple aspects of angiogenesis. In addition, several recent studies report that angiogenesis inhibition is associated to NF-κB activation. This is of special interest since in tumor cells NF-κB activation has been associated to inhibition of apoptosis and currently novel treatment strategies are being developed based on inhibition of NF-κB. The paradigm that systemic NF-κB inhibition can serve as an anti-cancer strategy, therefore, might need to be re-evaluated. Based on recent data, it might be speculated that NF-κB activation, when performed specifically in endothelial cells, could be an efficient strategy for the treatment of cancer