3,100 research outputs found
Spectral weight transfer in a disorder-broadened Landau level
In the absence of disorder, the degeneracy of a Landau level (LL) is
, where is the magnetic field, is the area of the sample
and is the magnetic flux quantum. With disorder, localized states
appear at the top and bottom of the broadened LL, while states in the center of
the LL (the critical region) remain delocalized. This well-known phenomenology
is sufficient to explain most aspects of the Integer Quantum Hall Effect (IQHE)
[1]. One unnoticed issue is where the new states appear as the magnetic field
is increased. Here we demonstrate that they appear predominantly inside the
critical region. This leads to a certain ``spectral ordering'' of the localized
states that explains the stripes observed in measurements of the local inverse
compressibility [2-3], of two-terminal conductance [4], and of Hall and
longitudinal resistances [5] without invoking interactions as done in previous
work [6-8].Comment: 5 pages 3 figure
Spinor-Vector Duality in Heterotic String Orbifolds
The three generation heterotic-string models in the free fermionic
formulation are among the most realistic string vacua constructed to date,
which motivated their detailed investigation. The classification of free
fermion heterotic string vacua has revealed a duality under the exchange of
spinor and vector representations of the SO(10) GUT symmetry over the space of
models. We demonstrate the existence of the spinor-vector duality using
orbifold techniques, and elaborate on the relation of these vacua to free
fermionic models.Comment: 20 pages. v2 minor corrections. Version to appear on JHEP. v3
misprints correcte
Patient safety in dentistry: development of a candidate 'never event' list for primary care
Introduction The 'never event' concept is often used in secondary care and refers to an agreed list of patient safety incidents that 'should not happen if the necessary preventative measures are in place'. Such an intervention may raise awareness of patient safety issues and inform team learning and system improvements in primary care dentistry.
Objective To identify and develop a candidate never event list for primary care dentistry.
Methods A literature review, eight workshops with dental practitioners and a modified Delphi with 'expert' groups were used to identify and agree candidate never events.
Results Two-hundred and fifty dental practitioners suggested 507 never events, reduced to 27 distinct possibilities grouped across seven themes. Most frequently occurring themes were: 'checking medical history and prescribing' (119, 23.5%) and 'infection control and decontamination' (71, 14%). 'Experts' endorsed nine candidate never event statements with one graded as 'extreme risk' (failure to check past medical history) and four as 'high risk' (for example, extracting wrong tooth).
Conclusion Consensus on a preliminary list of never events was developed. This is the first known attempt to develop this approach and an important step in determining its value to patient safety. Further work is necessary to develop the utility of this method
Dielectric and thermal relaxation in the energy landscape
We derive an energy landscape interpretation of dielectric relaxation times
in undercooled liquids, comparing it to the traditional Debye and
Gemant-DiMarzio-Bishop pictures. The interaction between different local
structural rearrangements in the energy landscape explains qualitatively the
recently observed splitting of the flow process into an initial and a final
stage. The initial mechanical relaxation stage is attributed to hopping
processes, the final thermal or structural relaxation stage to the decay of the
local double-well potentials. The energy landscape concept provides an
explanation for the equality of thermal and dielectric relaxation times. The
equality itself is once more demonstrated on the basis of literature data for
salol.Comment: 7 pages, 3 figures, 41 references, Workshop Disordered Systems,
Molveno 2006, submitted to Philosophical Magazin
A Geometric Approach to CP Violation: Applications to the MCPMFV SUSY Model
We analyze the constraints imposed by experimental upper limits on electric
dipole moments (EDMs) within the Maximally CP- and Minimally Flavour-Violating
(MCPMFV) version of the MSSM. Since the MCPMFV scenario has 6 non-standard
CP-violating phases, in addition to the CP-odd QCD vacuum phase \theta_QCD,
cancellations may occur among the CP-violating contributions to the three
measured EDMs, those of the Thallium, neutron and Mercury, leaving open the
possibility of relatively large values of the other CP-violating observables.
We develop a novel geometric method that uses the small-phase approximation as
a starting point, takes the existing EDM constraints into account, and enables
us to find maximal values of other CP-violating observables, such as the EDMs
of the Deuteron and muon, the CP-violating asymmetry in b --> s \gamma decay,
and the B_s mixing phase. We apply this geometric method to provide upper
limits on these observables within specific benchmark supersymmetric scenarios,
including extensions that allow for a non-zero \theta_QCD.Comment: 34 pages, 16 eps figures, to appear in JHE
3D human skin bioprinting: a view from the bio side
Based on the 3D printing technologies and the concepts developed in tissue engineering during the last decades, 3D bioprinting is emerging as the most innovative and promising technology for the generation of human tissues and organs. In the case of skin bioprinting, thanks to the research process carried out during the last years, interfollicular skin has been printed with a structural and functional quality that paves the way for clinical and industrial applications. This review analyzes the present achievements and the future improvements that this area must bring about if bioprinted skin is to become widely used. We have made an effort to integrate the technological and the biological/biomedical sides of the subject.We thank the Spanish Fundación Ramón Areces for its continuous support.
This work was partially supported by grant DPI2014-61887-EXP from the Spanish Ministerio de Economía y Competitividad
Sparticle Spectrum of Large Volume Compactification
We examine the large volume compactification of Type IIB string theory or its
F theory limit and the associated supersymmetry breakdown and soft terms. It is
crucial to incorporate the loop-induced moduli mixing, originating from
radiative corrections to the Kahler potential. We show that in the presence of
moduli mixing, soft scalar masses generically receive a D-term contribution of
the order of the gravitino mass m_{3/2} when the visible sector cycle is
stabilized by the D-term potential of an anomalous U(1) gauge symmetry, while
the moduli-mediated gaugino masses and A-parameters tend to be of the order of
m_{3/2}/8pi^2. It is noticed also that a too large moduli mixing can
destabilize the large volume solution by making it a saddle point.Comment: 29 page
Traumatic fracture of central venous catheter resulting in potential migration of distal fragment: a case report
We report a surgical retrieval of an indwelling portion of a traumatic rupture of the Central venous catheter following hair cutting by a confused patient secondary to Postoperative cognitive dysfunction. He had a dynamic compression screw for fixation of fractured neck of femur after previously failed surgical procedure. The second procedure was complicated with major blood loss, which required central venous and arterial line insertion for intra-operative and post-operative management. The patient was discharged to the ward following an uneventful stay on intensive care. While on the ward, he decided to trim his hair and in the process he inadvertently cut through the right internal jugular catheter. Complications and management resulting from embolisation of central line are reviewed
TIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53-deficient environment, and cell death
Self-aggregation of transforming growth factor β (TGF-β)1-induced antiapoptotic factor (TIAF1) is known in the nondemented human hippocampus, and the aggregating process may lead to generation of amyloid β (Aβ) for causing neurodegeneration. Here, we determined that overexpressed TIAF1 exhibits as aggregates together with Smad4 and Aβ in the cancer stroma and peritumor capsules of solid tumors. Also, TIAF1/Aβ aggregates are shown on the interface between brain neural cells and the metastatic cancer cell mass. TIAF1 is upregulated in developing tumors, but may disappear in established metastatic cancer cells. Growing neuroblastoma cells on the extracellular matrices from other cancer cell types induced production of aggregated TIAF1 and Aβ. In vitro induction of TIAF1 self-association upregulated the expression of tumor suppressors Smad4 and WW domain-containing oxidoreductase (WOX1 or WWOX), and WOX1 in turn increased the TIAF1 expression. TIAF1/Smad4 interaction further enhanced Aβ formation. TIAF1 is known to suppress SMAD-regulated promoter activation. Intriguingly, without p53, self-aggregating TIAF1 spontaneously activated the SMAD-regulated promoter. TIAF1 was essential for p53-, WOX1- and dominant-negative JNK1-induced cell death. TIAF1, p53 and WOX1 acted synergistically in suppressing anchorage-independent growth, blocking cell migration and causing apoptosis. Together, TIAF1 shows an aggregation-dependent control of tumor progression and metastasis, and regulation of cell death
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