11,523 research outputs found
Entrepreneurial intentions among students: towards a re-focused research agenda
Purpose â This paper aims to address the need for a re-focused research agenda in relation to graduate entrepreneurship. An important theme for some years has been the effort to monitor attitudes and intentions of students towards starting up their own businesses. It is timely, however, to raise some questions about both the impact of this research and likewise the general approach it has taken in understanding the phenomenon of graduate entrepreneurship. Design/methodology/approach â The paper draws on a large data set (over 8,000 students) from one UK region. Specifically, it presents data from the 2007/2008 Entrepreneurial Intentions (EI) survey within the Yorkshire and Humberside region and reflects back over previous iterations of this research. Findings â The paper identifies three key outcomes. First, it establishes that across all years of the survey a substantial minority of students consistently hold relatively strong start-up intentions. Second, the paper highlights that, despite considerable efforts to increase the numbers moving to start-up, little impact is discernible. Third, the paper suggests that, although the EI survey is useful as a stock-taking exercise, it fails to address critical questions around the impact of higher education on entrepreneurship and the transition from entrepreneurial intent to the act of venture creation. Originality/value â The paper provides an important positioning perspective on the relationship between higher education and graduate entrepreneurship. While highlighting the importance of the EI research, the paper establishes the need for a re-focused research agenda; one that is conceptually robust and with a focus on the student journey from higher education to graduate entrepreneur
On the relationship between inflation persistence and temporal aggregation
This paper examines the impact of temporal aggregation on alternative definitions of inflation persistence. Using the CPI and the core PCE deflator of the US, our results show that temporal aggregation from the monthly to the quarterly to the annual frequency induces persistence in the inflation series.
Counting fixed points and rooted closed walks of the singular map modulo powers of a prime
The "self-power" map modulo and its generalized form modulo are of considerable interest for both theoretical
reasons and for potential applications to cryptography. In this paper, we use
-adic methods, primarily -adic interpolation, Hensel's lemma, and lifting
singular points modulo , to count fixed points and rooted closed walks of
equations related to these maps when is a prime power. In particular, we
introduce a new technique for lifting singular solutions of several congruences
in several unknowns using the left kernel of the Jacobian matrix.Comment: 18 pages. Version 2 shortens proofs, reduces redundancy, and
introduces new technique for counting rooted closed walks. Version 3 updates
title to agree with journal publicatio
Localization of response functions of spiral waves in the FitzHugh-Nagumo system
Dynamics of spiral waves in perturbed, e. g. slightly inhomogeneous or
subject to a small periodic external force, two-dimensional autowave media can
be described asymptotically in terms of Aristotelean dynamics, so that the
velocities of the spiral wave drift in space and time are proportional to the
forces caused by the perturbation. The forces are defined as a convolution of
the perturbation with the spiral's Response Functions, which are eigenfunctions
of the adjoint linearised problem. In this paper we find numerically the
Response Functions of a spiral wave solution in the classic excitable
FitzHugh-Nagumo model, and show that they are effectively localised in the
vicinity of the spiral core.Comment: 11 pages, 2 figure
Soliton-like phenomena in one-dimensional cross-diffusion systems: a predator-prey pursuit and evasion example
We have studied properties of nonlinear waves in a mathematical model of a
predator-prey system with pursuit and evasion. We demonstrate a new type of
propagating wave in this system. The mechanism of propagation of these waves
essentially depends on the ``taxis'', represented by nonlinear
``cross-diffusion'' terms in the mathematical formulation. We have shown that
the dependence of the velocity of wave propagation on the taxis has two
distinct forms, ``parabolic'' and ``linear''. Transition from one form to the
other correlates with changes in the shape of the wave profile. Dependence of
the propagation velocity on diffusion in this system differs from the
square-root dependence typical of reaction-diffusion waves. We demonstrate also
that, for systems with negative and positive taxis, for example, pursuit and
evasion, there typically exists a large region in the parameter space, where
the waves demonstrate quasisoliton interaction: colliding waves can penetrate
through each other, and waves can also reflect from impermeable boundaries.Comment: 15 pages, 18 figures, submitted to Physica
The effect of on/off indicator design on state confusion, preference, and response time performance, executive summary
Investigated are five designs of software-based ON/OFF indicators in a hypothetical Space Station Power System monitoring task. The hardware equivalent of the indicators used in the present study is the traditional indicator light that illuminates an ON label or an OFF label. Coding methods used to represent the active state were reverse video, color, frame, check, or reverse video with check. Display background color was also varied. Subjects made judgments concerning the state of indicators that resulted in very low error rates and high percentages of agreement across indicator designs. Response time measures for each of the five indicator designs did not differ significantly, although subjects reported that color was the best communicator. The impact of these results on indicator design is discussed
MODIFIED PAMAM DENDRIMERS IN TUNABLE DRUG-DELIVERY SYSTEMS: A SUSTAINED-RELEASE DENDRIMER HYDROGEL FOR ANTI-GLAUCOMA DRUGS AND SURFACE-ENGINEERED MACROPHAGES AS NANOPARTICLE CARRIERS FOR TARGETED ANTI-CANCER THERAPY
Two specific drug-delivery applications were sought in this work using polyamidoamine (PAMAM) dendrimers. One drug-delivery system used a novel dendrimer hydrogel (DH) for sustained delivery of anti-glaucoma drugs. In this work, PAMAM G3.0 dendrimers were covalently bonded with poly(ethylene glycol) (PEGÂ12000) molecules which were subsequently acrylated, resulting in photocurable DH conjugates. For pharmacological studies, DH were loaded with a solution of intraocular pressure lowering drugs, brimonidine and timolol maleate, and were characterized for in vitro release and ex vivo transport and uptake. DH formulations were shown to increase the loading of drug molecules, increase transcorneal drug delivery, and exhibit sustained-delivery of drug molecules. A second drug-delivery system, utilizing cell-surface engineering, intended to increase the targeting ability of highly toxic anti-cancer drugs to curtail systemic effects. In particular, Qdots and 5-(aminoacetamido) fluorescein-labeled polyamidoamine dendrimer G4.5, both of which were coated with amine-derivatized polyethylene glycol, were immobilized to the sodium periodate-treated surface of RAW264.7 macrophages through a transient Schiff base linkage. Further, a reducing agent sodium cyanoborohydride was applied to reduce Schiff bases to stable secondary amine linkages. The distribution of nanoparticles on the cell surface was observed by fluorescence microscopy and was found to be dependent on the stability of the linkages tethering nanoparticles to the cell surface
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