From farm to table: exploring food handling and hygiene practices of meat and milk value chain actors in Ethiopia

Livestock value chains constitute a source of livelihood for meat and milk value chain actors in Ethiopia, from dairy farmers to other associated value chain actors such as milk traders, abattoir workers, public health officials, veterinarians, butcheries selling meats, milk cooperatives, artisanal milk processors, and transporters. The development of these livestock value chains, however, is constrained by poor food safety and quality, while consumers are also exposed to public health risks due to milk and meat value chain actors’ food handling and hygiene practices. This study used Photovoice and participant observation to explore meat and milk value chain actors’ food handling and hygiene practices in suburban areas of Addis Ababa and neighbouring Oromia in Ethiopia. The results of this study reveal that milk and meat value chain actors’ food handling practices are not aligned with the recommended Ethiopian food safety and quality standards. Low compliance with food safety and quality standards reflected a combination of factors such as lack of incentives, poor road infrastructure and low enforcement of food safety standards. Participatory and visual research methods enable a researcher to collect context-aware data that can lead to the development of policies and intervention strategies that reflect local needs and priorities. The results of this study affirm the need to identify socially acceptable and economically viable policies and intervention strategies that are acceptable to all chain actors; and suggest there is an imperative to train milk and meat value chain actors on good hygiene handling practices, improve road infrastructure, and facilitate access equipment such as fridges and freezers that can contribute to maintaining food safety and quality

Adoption of dairy technologies in smallholder dairy farms in Ethiopia

The adoption of modern agricultural technologies in Ethiopia’s dairy production system remains underutilized and under-researched yet it is a promising sector to aid in reducing poverty, improving the food security situation and the welfare of rural households, and in ensuring environmental sustainability. This paper uses the Negative Binomial regression model to examine determinants of multiple agricultural technology adoption in the Addis Ababa and Oromia regions of Ethiopia. Data was collected from 159 smallholder dairy farms in Ethiopia’s Addis Ababa and Oromia regions exploring 19 technologies used by the farmers during the study period. The findings show that farm location and herd size impact adoption decisions. Increasing herd size is associated with increased uptake of multiple technologies. Further, as farmer education level increases the more likely farmers are to adopt multiple technologies. The increase in the number of female workers is positively associated with the adoption of multiple dairy technologies. In terms of farmers’/workers’ years of experience, those with no years of work experience are less likely to have adopted multiple technologies than those with more than 5 years of experience. However, this could be due to a number of factors where experience stands as a proxy value. Trust in information from government agencies was associated with a higher propensity to adopt multiple dairy technology as was farmer perception of fellow farmers as peers compared to those who perceive them as competitors. This is an important finding as it may help policymakers or institutions explore knowledge exchange and diffusion of innovation strategies tailored to specific farming and community situations. Studies have shown that farmers within a social group learn from each other more fully about the benefits and usage of new technology. These findings are of value in future technology adoption studies, particularly which factors influence the intensity of adoption of multiple technologies by smallscale producers

Effects of cyclooxygenase-1 and -2 gene disruption on Helicobacter pylori-induced gastric inflammation

Background. Cyclooxygenases (COXs) play important roles in inflammation and carcinogenesis. The present study aimed to determine the effects of COX-1 and COX-2 gene disruption on Helicobacter pylori-induced gastric inflammation. Methods. Wild-type (WT), COX-1 and COX-2 heterozygous (COX-1 +/- and COX-2 +/-), and homozygous COX-deficient (COX-1 -/- and COX-2 -/-) mice were inoculated with H. pylori strain TN2 and killed after 24 weeks of infection. Uninfected WT and COX-deficient mice were used as controls. Levels of gastric mucosal inflammation, epithelial cell proliferation and apoptosis, and cytokine expression were determined. Results. COX deficiency facilitated H. pylori-induced gastritis. In the presence of H. pylori infection, apoptosis was increased in both WT and COX-deficient mice, whereas cell proliferation was increased in WT and COX-1-deficient, but not in COX-2-deficient, mice. Tumor necrosis factor (TNF)-α and interleukin-10 mRNA expression was elevated in H. pylori-infected mice, but only TNF-α mRNA expression was further increased by COX deficiency. Prostaglandin E 2 levels were increased in infected WT and COX-2-deficient mice but were at very low levels in infected COX-1-deficient mice. Leukotriene (LT) B 4 and LTC 4 levels were increased to a similar extent in infected WT and COX-deficient mice. Conclusions. COX deficiency enhances H. pylori-induced gastritis, probably via TNF-α expression. COX-2, but not COX-1, deficiency suppresses H. pylori-induced cell proliferation. © 2006 by the Infectious Diseases Society of America. All rights reserved.published_or_final_versio

Genetic Covariance Structure of Reading, Intelligence and Memory in Children

This study investigates the genetic relationship among reading performance, IQ, verbal and visuospatial working memory (WM) and short-term memory (STM) in a sample of 112, 9-year-old twin pairs and their older siblings. The relationship between reading performance and the other traits was explained by a common genetic factor for reading performance, IQ, WM and STM and a genetic factor that only influenced reading performance and verbal memory. Genetic variation explained 83% of the variation in reading performance; most of this genetic variance was explained by variation in IQ and memory performance. We hypothesize, based on these results, that children with reading problems possibly can be divided into three groups: (1) children low in IQ and with reading problems; (2) children with average IQ but a STM deficit and with reading problems; (3) children with low IQ and STM deficits; this group may experience more reading problems than the other two

Strategies for Animal Disease Control in Ethiopia: A Review of Policies, Regulations and Actors

Ethiopia has the largest livestock population of any country in Africa, making a considerable contribution to the livelihood of Ethiopian people and to the wider economy. However, zoonotic diseases threaten the performance and potential benefits of this vast livestock sector. Emerging zoonotic diseases, such as bovine tuberculosis, brucellosis and anthrax, that have acquired global significance, are seriously affecting the livestock sector in the country. A number of policies and regulations have been designed in order to prevent and control the transmission of animal and zoonotic diseases in Ethiopia. This paper documents the key policy provisions and institutions involved in these initiatives and identifies entry points for the design of specific implementable strategies for the control of bovine tuberculosis (bTB): a disease that is endemic among cattle in Ethiopia and particularly highly prevalent in its dairy sector. Our analysis is based on a review of existing documentation carried out during 2017.The results indicate: (i) the existence of various policy provisions for disease prevention and control, but with limited recognition of different disease transmission pathways including ‘animal to animal’, ‘animal to human’, and ‘human to animal’; (ii) that these policies and regulations only provide a general framework without specifying the interventions related to specific disease types e.g. bTB; (iii) that different institutions are given similar tasks and that there is no strong coordination mechanism among the institutions in terms of fulfilling these tasks and avoiding the duplication of effort, and (iv) that so far, more attention has been given to policies on human health, especially relating to selected priority diseases. These trends imply the need to design and implement strategic interventions in the prevention and control of bTB transmission both within the animal population and from the animal to the human population

A framework for ETH-Tight algorithms and lower bounds in geometric intersection graphs

We give an algorithmic and lower-bound framework that facilitates the construction of subexponential algorithms and matching conditional complexity bounds. It can be applied to a wide range of geometric intersection graphs (intersections of similarly sized fat objects), yielding algorithms with running time 2O(n1−1/d) for any fixed dimension d ≥ 2 for many well known graph problems, including Independent Set, r-Dominating Set for constant r, and Steiner Tree. For most problems, we get improved running times compared to prior work; in some cases, we give the first known subexponential algorithm in geometric intersection graphs. Additionally, most of the obtained algorithms work on the graph itself, i.e., do not require any geometric information. Our algorithmic framework is based on a weighted separator theorem and various treewidth techniques. The lower bound framework is based on a constructive embedding of graphs into d-dimensional grids, and it allows us to derive matching 2Ω(n1−1/d) lower bounds under the Exponential Time Hypothesis even in the much more restricted class of d-dimensional induced grid graphs

Axion monodromy in a model of holographic gluodynamics

The low energy field theory for N type IIA D4-branes at strong 't Hooft coupling, wrapped on a circle with antiperiodic boundary conditions for fermions, is known to have a vacuum energy which depends on the $\theta$ angle for the gauge fields, and which is a multivalued function of this angle. This gives a field-theoretic realization of "axion monodromy" for a nondynamical axion. We construct the supergravity solution dual to the field theory in the metastable state which is the adiabatic continuation of the vacuum to large values of $\theta$. We compute the energy of this state and show that it initially rises quadratically and then flattens out. We show that the glueball mass decreases with $\theta$, becoming much lower than the 5d KK scale governing the UV completion of this model. We construct two different classes of domain walls interpolating between adjacent vacua. We identify a number of instability modes -- nucleation of domain walls, bulk Casimir forces, and condensation of tachyonic winding modes in the bulk -- which indicate that the metastable branch eventually becomes unstable. Finally, we discuss two phenomena which can arise when the axion is dynamical; axion-driven inflation, and axion strings.Comment: 43 pages, 10 figures. v2: references update

A Minimal Model of Metabolism Based Chemotaxis

Since the pioneering work by Julius Adler in the 1960's, bacterial chemotaxis has been predominantly studied as metabolism-independent. All available simulation models of bacterial chemotaxis endorse this assumption. Recent studies have shown, however, that many metabolism-dependent chemotactic patterns occur in bacteria. We hereby present the simplest artificial protocell model capable of performing metabolism-based chemotaxis. The model serves as a proof of concept to show how even the simplest metabolism can sustain chemotactic patterns of varying sophistication. It also reproduces a set of phenomena that have recently attracted attention on bacterial chemotaxis and provides insights about alternative mechanisms that could instantiate them. We conclude that relaxing the metabolism-independent assumption provides important theoretical advances, forces us to rethink some established pre-conceptions and may help us better understand unexplored and poorly understood aspects of bacterial chemotaxis

Characteristics of fast voluntary and electrically evoked isometric knee extensions during 56 days of bed rest with and without exercise countermeasure

The contractile characteristics of fast voluntary and electrically evoked unilateral isometric knee extensions were followed in 16 healthy men during 56 days of horizontal bed rest and assessed at bed rest days 4, 7, 10, 17, 24, 38 and 56. Subjects were randomized to either an inactive control group (Ctrl, n = 8) or a resistive vibration exercise countermeasure group (RVE, n = 8). No changes were observed in neural activation, indicated by the amplitude of the surface electromyogram, or the initial rate of voluntary torque development in either group during bed rest. In contrast, for Ctrl, the force oscillation amplitude at 10 Hz stimulation increased by 48% (P < 0.01), the time to reach peak torque at 300 Hz stimulation decreased by 7% (P < 0.01), and the half relaxation time at 150 Hz stimulation tended to be slightly reduced by 3% (P = 0.056) after 56 days of bed rest. No changes were observed for RVE. Torque production at 10 Hz stimulation relative to maximal (150 Hz) stimulation was increased after bed rest for both Ctrl (15%; P < 0.05) and RVE (41%; P < 0.05). In conclusion, bed rest without exercise countermeasure resulted in intrinsic speed properties of a faster knee extensor group, which may have partly contributed to the preserved ability to perform fast voluntary contractions. The changes in intrinsic contractile properties were prevented by resistive vibration exercise, and voluntary motor performance remained unaltered for RVE subjects as well

Maximal Spontaneous Photon Emission and Energy Loss from Free Electrons

Free electron radiation such as Cerenkov, Smith--Purcell, and transition radiation can be greatly affected by structured optical environments, as has been demonstrated in a variety of polaritonic, photonic-crystal, and metamaterial systems. However, the amount of radiation that can ultimately be extracted from free electrons near an arbitrary material structure has remained elusive. Here we derive a fundamental upper limit to the spontaneous photon emission and energy loss of free electrons, regardless of geometry, which illuminates the effects of material properties and electron velocities. We obtain experimental evidence for our theory with quantitative measurements of Smith--Purcell radiation. Our framework allows us to make two predictions. One is a new regime of radiation operation---at subwavelength separations, slower (nonrelativistic) electrons can achieve stronger radiation than fast (relativistic) electrons. The second is a divergence of the emission probability in the limit of lossless materials. We further reveal that such divergences can be approached by coupling free electrons to photonic bound states in the continuum (BICs). Our findings suggest that compact and efficient free-electron radiation sources from microwaves to the soft X-ray regime may be achievable without requiring ultrahigh accelerating voltages.Comment: 7 pages, 4 figure