10,478 research outputs found

    Relaxed stability conditions based on Taylor series membership functions for polynomial fuzzy-model-based control systems

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    © 2014 IEEE. In this paper, we investigate the stability of polynomial fuzzy-model-based (PFMB) control systems, aiming to relax stability conditions by considering the information of membership functions. To facilitate the stability analysis, we propose a general form of approximated membership functions, which is implemented by Taylor series expansion. Taylor series membership functions (TSMF) can be brought into stability conditions such that the relation between membership grades and system states is expressed. To further reduce the con-servativeness, different types of information are taken into account: the boundary of membership functions, the property of membership functions, and the boundary of operating domain. Stability conditions are obtained from Lyapunov stability theory by sum of squares (SOS) approach. Simulation examples demonstrate the effect of each piece of information

    Power distance orientation alleviates the beneficial effects of empowering leadership on actors' work engagement via negative affect and sleep quality

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    Although many studies have explored the benefits of empowering leadership for followers, the beneficial effect of such behavior for actors who demonstrate empowering leadership has been overlooked. Applying conservation of resources theory, we propose and test a model that determines why and when empowering leadership benefits actors. We use an experience sampling survey to examine the effect of empowering leadership on actors’ daily work engagement. In particular, we focus on the moderating role of power distance orientation and the mediating roles of negative affect and sleep quality, which operate sequentially. The results based on responses from 160 supervisors in two Chinese organizations indicated that empowering leadership in the morning was negatively related to negative affect in the afternoon and positively related to sleep quality at night and next-day work engagement. The strength of this beneficial effect was moderated by power distance orientation, such that supervisors with a high degree of power distance orientation obtained fewer benefits from empowering leadership than those with a low degree of power distance orientation. The theoretical and practical implications of these findings for the leadership, affect, sleep, power distance, and conservation of resources literatures are discussed

    Upregulation of the microRNA cluster at the Dlk1-Dio3 locus in lung adenocarcinoma.

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    Mice in which lung epithelial cells can be induced to express an oncogenic Kras(G12D) develop lung adenocarcinomas in a manner analogous to humans. A myriad of genetic changes accompany lung adenocarcinomas, many of which are poorly understood. To get a comprehensive understanding of both the transcriptional and post-transcriptional changes that accompany lung adenocarcinomas, we took an omics approach in profiling both the coding genes and the non-coding small RNAs in an induced mouse model of lung adenocarcinoma. RNAseq transcriptome analysis of Kras(G12D) tumors from F1 hybrid mice revealed features specific to tumor samples. This includes the repression of a network of GTPase-related genes (Prkg1, Gnao1 and Rgs9) in tumor samples and an enrichment of Apobec1-mediated cytosine to uridine RNA editing. Furthermore, analysis of known single-nucleotide polymorphisms revealed not only a change in expression of Cd22 but also that its expression became allele specific in tumors. The most salient finding, however, came from small RNA sequencing of the tumor samples, which revealed that a cluster of ∌53 microRNAs and mRNAs at the Dlk1-Dio3 locus on mouse chromosome 12qF1 was markedly and consistently increased in tumors. Activation of this locus occurred specifically in sorted tumor-originating cancer cells. Interestingly, the 12qF1 RNAs were repressed in cultured Kras(G12D) tumor cells but reactivated when transplanted in vivo. These microRNAs have been implicated in stem cell pleuripotency and proteins targeted by these microRNAs are involved in key pathways in cancer as well as embryogenesis. Taken together, our results strongly imply that these microRNAs represent key targets in unraveling the mechanism of lung oncogenesis

    Generalized Spring Tensor Model: A New Improved Load Balancing Method in Cloud Computing

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    Significant characteristics of cloud computing such as elasticity, scalability and payment model attract businesses to replace their legacy infrastructure with the newly offered cloud technologies. As the number of the cloud users is growing rapidly, extensive load volume will affect performance and operation of the cloud. Therefore, it is essential to develop smarter load management methods to ensure effective task scheduling and efficient management of resources. In order to reach these goals, varieties of algorithms have been explored and tested by many researchers. But so far, not many operational load balancing algorithms have been proposed that are capable of forecasting the future load patterns in cloud-based systems. The aim of this research is to design an effective load management tool, characterized by collective behavior of the workflow tasks and jobs that is able to predict various dynamic load patterns occurring in cloud networks. The results show that the proposed new load balancing algorithm can visualize the network load by projecting the existing relationships among submitted tasks and jobs. The visualization can be particularly useful in terms of monitoring the robustness and stability of the cloud systems. © Springer International Publishing Switzerland 2015

    Ameliorating effect of Erxian decoction combined with Fructus Schisandrae chinensis (Wu Wei Zi) on menopausal sweating and serum hormone profiles in a rat model.

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    Background Modified Erxian decoction (MEXD), i.e., Erxian decoction (EXD) with Fructus Schisandrae chinensis (Wu Wei Zi) added, has been used to alleviate menopausal symptoms. This study aimed to investigate the effects of MEXD on menopausal sweating and serum hormone levels in a rat model of menopause after oral administration of MEXD. Methods Quality control of MEXD was conducted by employing a reversed-phase high performance liquid chromatography column. The three treatment groups received oral administration of MEXD in 0.5% sodium carboxylmethyl cellulose (CMC-Na) at three different doses (5.5, 11, and 22 g/kg body weight) once-daily for 6 consecutive weeks, with 10 animals per group. Huangqijing oral liquor (5 mL/kg) prepared from the roots of Huang qi (Astragalus membranaceus) with an antiperspirant effect was used as a positive control. The negative control group received the same volume of vehicle (0.5% CMC-Na). Ten 3-month-old Sprague–Dawley rats were used as a young group for comparison with the treatment groups (12–14 months old rats). Blood was collected from all animals after 3–6 weeks of treatment. At the end of the treatment, the uterine weight, ovarian weight, and body weight were recorded. Serum malondialdehyde contents and superoxide dismutase activities were determined by thiobarbituric acid colorimetric assays and chemoluminescence assays, respectively. Serum levels of estradiol, follicle-stimulating hormone, and luteinizing hormone were measured by radioimmunoassays. Rat foot pad assays were used to determine the antiperspirant activity of MEXD and histological examinations were conducted on plantar sweat glands. Results Treatment with MEXD (11 g/kg) significantly inhibited sweat excretion in the menopause model rats after treatment for 3 (P = 0.0026) and 6 (P < 0.0001) weeks. The decoction markedly decreased the number of secretory cells in plantar sweat glands. In addition, MEXD (11 g/kg) significantly increased the serum estradiol levels (P < 0.001) and superoxide dismutase activities (P = 0.0405). Furthermore, MEXD (11 g/kg) markedly decreased the serum levels of follicle-stimulating hormone (P = 0.001), luteinizing hormone (P = 0.0213), and malondialdehyde (P = 0.01). Conclusion Modified Erxian decoction significantly inhibited sweat excretion, regulated serum levels of pituitary gonadotropins and estradiol, and exhibited antioxidative effects in a rat model of menopause.published_or_final_versio

    Environmental production and productivity growth: evidence from european paper and pulp manufacturing

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    © 2018, Springer Science+Business Media, LLC, part of Springer Nature. The production and manufacturing sector is one of the primary factors that affects the environment, which has been a very important topic of recent studies. Many approaches are employed to reduce the impact of production on the environment. More recently, carbon-abatement technology and activities have been introduced into the production processes to reduce carbon emissions, such as the implementation of emission trading programs in many industrial sectors, including the paper and pulp sector. Nevertheless, the costs of abatement activities will result in a certain level of sacrifice in productivity growth, when the inputs are reallocated from good output production to abatement activities to maintain bad output under the regulatory limit. However, how and the extent to which such technology will affect productivity remain unclear. Therefore, it is worth investigating the opportunity cost of introducing such technology. In this paper, we offer new empirical evidence by studying panel data on 17 EU member states from 1995 to 2006. Productivity changes are calculated using a data envelopment directional distance function with and without adapting the carbon-abatement technology in the paper and pulp production. The results support our concern about the potential opportunity cost of introducing carbon-abatement technology, which leads to a decline in productivity growth. In addition, industrial production is not operating efficiently; on average it moves further away from the efficient production frontier over time

    Coronary angiography enhancement for visualization

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    High quality visualization on X-ray angiograms is of great significance both for the diagnosis of vessel abnormalities and for coronary interventions. Algorithms for improving the visualization of detailed vascular structures without significantly increasing image noise are currently demanded in the market. A new algorithm called stick-guided lateral inhibition (SGLI) is presented for increasing the visibility of coronary vascular structures. A validation study was set up to compare the SGLI algorithm with the conventional unsharp masking (UM) algorithm on 20 still frames of coronary angiographic images. Ten experienced QCA analysts and nine cardiologists from various centers participated in the validation. Sample scoring value (SSV) and observer agreement value (OAV) were defined to evaluate the validation result, in terms of enhancing performance and observer agreement, respectively. The mean of SSV was concluded to be 77.1 ± 11.9%, indicating that the SGLI algorithm performed significantly better than the UM algorithm (P-value < 0.001). The mean of the OAV was concluded to be 70.3%, indicating that the average agreement with respect to a senior cardiologist was 70.3%. In conclusion, this validation study clearly demonstrates the superiority of the SGLI algorithm in the visualization of coronary arteries from X-ray angiograms

    Dehydration of forward osmosis membranes in treating high salinity wastewaters: Performance and implications

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    © 2015 Elsevier B.V. Forward osmosis (FO) is a promising technique for desalinating high salinity wastewaters, and membrane performance is critical for its successful application. In this work, the dehydration of FO membranes was demonstrated for both commercial cellulose triacetate and tailor-made thin-film composite membranes. A significant loss of FO flux was observed after membrane dehydration, but the pure water permeability and rejection properties remained about the same. Dehydrated membrane showed opaque/white spots on the initially homogeneous membrane. Once dehydrated, a membrane with a much lower water flux will be resulting in. It was demonstrated that when the active skin layer was in contact with the saline solution before the support layer was brought into contact with an aqueous solution, membrane dehydration took place. The dehydration was ascribed to osmosis gradient across the active layer that caused water flow from membrane support layer to the active layer, resulting in support dehydration. The dehydrated membrane could be rewetted again by low surface tension liquid or reverse osmosis, illustrating that membrane dehydration is reversible. Precaution should be addressed when operating large FO system to prevent the membrane dehydration for high salinity water treatment

    Dynamical R-parity Breaking at the LHC

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    In a class of extensions of the minimal supersymmetric standard model with (B-L)/left-right symmetry that explains the neutrino masses, breaking R-parity symmetry is an essential and dynamical requirement for successful gauge symmetry breaking. Two consequences of these models are: (i) a new kind of R-parity breaking interaction that protects proton stability but adds new contributions to neutrinoless double beta decay and (ii) an upper bound on the extra gauge and parity symmetry breaking scale which is within the large hadron collider (LHC) energy range. We point out that an important prediction of such theories is a potentially large mixing between the right-handed charged lepton (ece^c) and the superpartner of the right-handed gauge boson (W~R+\widetilde W_R^+), which leads to a brand new class of R-parity violating interactions of type ÎŒc~†ΜΌcec\widetilde{\mu^c}^\dagger\nu_\mu^c e^c and \widetilde{d^c}^\dagger\u^c e^c. We analyze the relevant constraints on the sparticle mass spectrum and the LHC signatures for the case with smuon/stau NLSP and gravitino LSP. We note the "smoking gun" signals for such models to be lepton flavor/number violating processes: pp→Ό±Ό±e+e−jjpp\to \mu^\pm\mu^\pm e^+e^-jj (or τ±τ±e+e−jj\tau^\pm\tau^\pm e^+e^-jj) and pp→Ό±e±bbˉjjpp\to\mu^\pm e^\pm b \bar{b} jj (or τ±e±bbˉjj\tau^\pm e^\pm b \bar{b} jj) without significant missing energy. The predicted multi-lepton final states and the flavor structure make the model be distinguishable even in the early running of the LHC.Comment: 30 pages, 13 figures, 6 tables, reference adde

    Monolithic semiconductor lasers with dynamically tunable linear-to-circular polarization

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    The ability to control the polarization state of emission from semiconductor lasers is essential for many applications in spectroscopy, imaging, and communications, inter alia, with monolithic integration approaches being extremely beneficial. Although manipulating the output polarization of radiation from a laser can be achieved through a number of approaches, obtaining continuous dynamic control, e.g., from linear to circular, remains extremely challenging. In this paper, we demonstrate that the polarization of terahertz (THz) frequency radiation can be continuously tuned electronically from linear to circular polarization by monolithically integrating in-plane metasurfaces with two phase-locked semiconductor-based THz quantum cascade lasers. Moreover, the metasurfaces—metal antenna arrays in this case—also act as efficient beam collimators, yielding a collimated beam divergence of ∌10° × 10°. Our results, however, have broad applicability to a wide range of semiconductor lasers operating from the visible to THz regions of the electromagnetic spectrum
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