Targeting Escalation and Harm in Intimate Partner Violence: Evidence from Northern Territory Police, Australia

Research Question: Does analysis of intimate partner violence (IPV) among Aboriginal and non-Aboriginal couples in the Northern Territory (NT), Australia reveal any predictable escalation in frequency or severity of harm over a four-year observation period? Data: We examined all 61,796 incidents of IPV recorded by the NT Police for 23,104 unique couples (‘dyads’), over the five year period from 1 January 2010 to 31 December 2014. For purposes of analysing changes over time in frequency and harm, we used standardized observation periods (generally four years) from first incident to end of observations. Methods: Each IPV incident was re-classified by crime type using the penal code of England and Wales, in order to measure the severity of harm in NT with the Cambridge Crime Harm Index (CHI). The CHI scores were used to test for patterns of concentration and escalation, based on the total days of recommended imprisonment for each offence type, summed across all offences of that type for the entire sample. Findings: The findings were sharply split between Aboriginal and white dyads. While there was no evidence of escalation in either frequency or severity of IPV 2 incidents in the white dyads, there was substantial evidence of escalation among Aboriginal offenders with three or more incidents in a four year period. Less than 2% of white offenders (2 of 111) had three or more incidents in four years, compared to 32.4% of Aboriginals (N = 105 out of 355 offenders). For those couples of both races known by police to have two or more incidents, there was a strong pattern of escalation in the frequency and seriousness of offending for up to 20 incidents over four years. While 66% of couples had desisted by year 3 with no further reports that year or the next, among the 34% of couples (N= 3,621) persisting into year 3 the probability of a new incident by year 4 was 99.9%. Similarly, the time between incidents for these repeaters declined with each new incident, indicating an increase in frequency. Severity of harm also rose with repeated incidents, from 0.6 of expected Cambridge CHI value per dyad among couples with 1 to 5 incidents over four years to 3.82 times higher than expected value per dyad among those couples observed to have 16-20 incidents over four years—six times more harm among couples (almost entirely Aboriginals) with the highest frequency of incidents than among couples with the lowest frequency. Conclusions: This targeting analysis confirms other research that shows no escalation in frequency or severity of domestic abuse among predominantly white European populations. Yet it also provides the first systematic test of the escalation hypothesis about IPV reported to police among Australian Aboriginal dyads. That evidence provides a strong basis in evidence for developing a two-track policy for policing IPV in Australian areas with substantial Indigenous populations. Track 1 would serve dyads (of either race) presenting for the first or second time, for whom a light touch may generally be sufficient. Yet any couple known to have had two or more prior offences could receive a far more intensive 3 strategic investment, including the testing of new strategies for prevention of escalation in harm or frequency of IPV. Yet because this pattern of escalation is found only in a minority of Aboriginal dyads, it is important to base policy on evidence-based targeting of dyads with prior occurrences rather than race. KEY WORDS: Intimate Partner Violence/Domestic Abuse/ Aboriginal Offenders and Victims/ Police/ Evidence-Based Targetin

Negotiated Order:The Groundwork for a Theory of Offending Pathways

This article explores the role which formal and informal regulatory orders play in the development of offender identity. Drawing on quantitative and qualitative data from the Edinburgh Study of Youth Transitions and Crime, it argues that the cultural practices of formal orders (such as those imposed by schools and the police) and informal orders (such as the rules governing peer interactions) mirror each other in respect of their fundamental dynamics – animated primarily by an inclusionary–exclusionary imperative. Formal orders differentiate between categories of young people on the basis of class and suspiciousness. Informal orders differentiate between individuals on the basis of adherence to group norms, territorial sovereignty, and gender appropriate demeanour. Being excluded by either set of orders undermines the capacity of the individual to negotiate, limits autonomy and constrains choice. This renders the individual more likely to absorb identities ascribed to them with damaging consequences in terms of offending behaviour and the individual’s sense of self

Secular evolution versus hierarchical merging: galaxy evolution along the Hubble sequence, in the field and rich environments

In the current galaxy formation scenarios, two physical phenomena are invoked to build disk galaxies: hierarchical mergers and more quiescent external gas accretion, coming from intergalactic filaments. Although both are thought to play a role, their relative importance is not known precisely. Here we consider the constraints on these scenarios brought by the observation-deduced star formation history on the one hand, and observed dynamics of galaxies on the other hand: the high frequency of bars and spirals, the high frequency of perturbations such as lopsidedness, warps, or polar rings. All these observations are not easily reproduced in simulations without important gas accretion. N-body simulations taking into account the mass exchange between stars and gas through star formation and feedback, can reproduce the data, only if galaxies double their mass in about 10 Gyr through gas accretion. Warped and polar ring systems are good tracers of this accretion, which occurs from cold gas which has not been virialised in the system's potential. The relative importance of these phenomena are compared between the field and rich clusters. The respective role of mergers and gas accretion vary considerably with environment.Comment: 18 pages, 8 figures, review paper to "Penetrating Bars through Masks of Cosmic Dust: the Hubble Tuning Fork Strikes a New Note", Pilanesberg, ed. D. Block et al., Kluwe

Preliminary effects and acceptability of a co-produced physical activity referral intervention

Objectives: To explore the preliminary effects and acceptability of a co-produced physical activity referral intervention. Study Design: Longitudinal design with data collected at baseline and post a 12-week physical activity referral intervention. Setting. Community leisure centre. Methods: 32 adults with controlled lifestyle-related health conditions took part in a physical activity referral intervention (co-produced by a multidisciplinary stakeholder group) comprising 12 weeks’ subsidised fitness centre access plus four behaviour change consultations. A complete case analysis (t-tests and magnitude-based inferences) was conducted to assess baseline-to-12-week change in physical activity, cardiometabolic, and psychological measures. Semi-structured interviews were conducted (n=12) to explore experiences of the intervention. Results: Mean improvements were observed in cardiorespiratory fitness-2 (3.6 ml.kg.-1min-1 (95% confidence interval 1.9 to 5.4) P<0.001) and moderate-to-vigorous physical activity (12.6 min.day (95% CI 4.3 to 29.6) P=0.013). Participants were positive about the support from exercise referral practitioners, but experienced some challenges in a busy and under staffed gym environment. Conclusions: A co-produced physical activity referral intervention elicited short-term improvements in physical activity and cardiometabolic health. Further refinements may be required, via ongoing feedback between stakeholders, researchers and service users, to achieve the intended holistic physical activity focus of the intervention, prior to a definitive trial

Chronic multifocal non-bacterial osteomyelitis in hypophosphatasia mimicking malignancy

BACKGROUND: Hypophosphatasia (HP) is characterized by a genetic defect in the tissue-nonspecific alkaline phosphatase (TNSALP) gene and predominantly an autosomal recessive trait. HP patients suffer from reduced bone mineralization. Biochemically, elevated concentrations of substrates of TNSALP, including pyridoxal-5'-phosphate and inorganic pyrophosphate occur in serum, tissues and urine. The latter has been associated with chronic inflammation and hyperprostaglandinism. CASE PRESENTATION: We report on 2 affected children presenting with multifocal inflammatory bone lesions mimicking malignancy: A 6 years old girl with short stature had been treated with human growth hormone since 6 months. Then she started to complain about a painful swelling of her left cheek. MRI suggested a malignant bone lesion. Bone biopsy, however, revealed chronic inflammation. A bone scan showed a second rib lesion. Since biopsy was sterile, the descriptive diagnosis of chronic non-bacterial osteomyelitis (CNO) was established. The diagnostic tests related to growth failure were repeated and subsequent analyses demonstrated a molecular defect in the TNSALP gene. The second girl (10 years old) complained about back pain after she had fallen from her bike. X rays of her spine revealed compressions of 2 thoracic vertebrae. At first these were considered trauma related, however a bone scan did show an additional lesion in the right 4(th )rib. A biopsy of this rib revealed a sterile lympho- plasmocytoid osteomyelitis suggesting multifocal CNO. Further analyses did show a decreased TNSALP in leukocytes and elevated pyridoxal phosphate in plasma, suggesting a heterozygous carrier status of HP. CONCLUSION: Chronic bone oedema in adult HP and chronic hyper-prostaglandinism in childhood HP do suggest that in some HP patients bone inflammation is present in conjunction with the metabolic defect. Sterile multifocal osteomyelitis could be demonstrated. Non-steroidal anti-inflammatory treatment achieved complete remission. These cases illustrate chronic inflammation of the bone as a new feature of HP

Pragmatic evaluation of a coproduced physical activity referral scheme:a UK quasi-experimental study

Contains fulltext : 226129.pdf (publisher's version ) (Open Access

GFI1 proteins regulate stem cell formation in the AGM

In vertebrates, the first haematopoietic stem cells (HSCs) with multi-lineage and long-term repopulating potential arise in the AGM (aorta-gonad-mesonephros) region. These HSCs are generated from a rare and transient subset of endothelial cells, called haemogenic endothelium (HE), through an endothelial-to-haematopoietic transition (EHT). Here, we establish the absolute requirement of the transcriptional repressors GFI1 and GFI1B (growth factor independence 1 and 1B) in this unique trans-differentiation process. We first demonstrate that Gfi1 expression specifically defines the rare population of HE that generates emerging HSCs. We further establish that in the absence of GFI1 proteins, HSCs and haematopoietic progenitor cells are not produced in the AGM, revealing the critical requirement for GFI1 proteins in intra-embryonic EHT. Finally, we demonstrate that GFI1 proteins recruit the chromatin-modifying protein LSD1, a member of the CoREST repressive complex, to epigenetically silence the endothelial program in HE and allow the emergence of blood cells.We thank the staff at the Advanced Imaging, animal facility, Molecular Biology Core facilities and Flow Cytometry of CRUK Manchester Institute for technical support and Michael Lie-A-Ling and Elli Marinopoulou for initiating the DamID-PIP bioinformatics project. We thank members of the Stem Cell Biology group, the Stem Cell Haematopoiesis groups and Martin Gering for valuable advice and critical reading of the manuscript. Work in our laboratory is supported by the Leukaemia and Lymphoma Research Foundation (LLR), Cancer Research UK (CRUK) and the Biotechnology and Biological Sciences Research Council (BBSRC). SC is the recipient of an MRC senior fellowship (MR/J009202/1).This is the author accepted manuscript. The final version is available from NPG via http://dx.doi.org/10.1038/ncb327

Hypophosphatasia

Hypophosphatasia is a rare inherited disorder characterized by defective bone and teeth mineralization, and deficiency of serum and bone alkaline phosphatase activity. The prevalence of severe forms of the disease has been estimated at 1/100 000

SLAM algorithm applied to robotics assistance for navigation in unknown environments

<p>Abstract</p> <p>Background</p> <p>The combination of robotic tools with assistance technology determines a slightly explored area of applications and advantages for disability or elder people in their daily tasks. Autonomous motorized wheelchair navigation inside an environment, behaviour based control of orthopaedic arms or user's preference learning from a friendly interface are some examples of this new field. In this paper, a Simultaneous Localization and Mapping (SLAM) algorithm is implemented to allow the environmental learning by a mobile robot while its navigation is governed by electromyographic signals. The entire system is part autonomous and part user-decision dependent (semi-autonomous). The environmental learning executed by the SLAM algorithm and the low level behaviour-based reactions of the mobile robot are robotic autonomous tasks, whereas the mobile robot navigation inside an environment is commanded by a Muscle-Computer Interface (MCI).</p> <p>Methods</p> <p>In this paper, a sequential Extended Kalman Filter (EKF) feature-based SLAM algorithm is implemented. The features correspond to lines and corners -concave and convex- of the environment. From the SLAM architecture, a global metric map of the environment is derived. The electromyographic signals that command the robot's movements can be adapted to the patient's disabilities. For mobile robot navigation purposes, five commands were obtained from the MCI: turn to the left, turn to the right, stop, start and exit. A kinematic controller to control the mobile robot was implemented. A low level behavior strategy was also implemented to avoid robot's collisions with the environment and moving agents.</p> <p>Results</p> <p>The entire system was tested in a population of seven volunteers: three elder, two below-elbow amputees and two young normally limbed patients. The experiments were performed within a closed low dynamic environment. Subjects took an average time of 35 minutes to navigate the environment and to learn how to use the MCI. The SLAM results have shown a consistent reconstruction of the environment. The obtained map was stored inside the Muscle-Computer Interface.</p> <p>Conclusions</p> <p>The integration of a highly demanding processing algorithm (SLAM) with a MCI and the communication between both in real time have shown to be consistent and successful. The metric map generated by the mobile robot would allow possible future autonomous navigation without direct control of the user, whose function could be relegated to choose robot destinations. Also, the mobile robot shares the same kinematic model of a motorized wheelchair. This advantage can be exploited for wheelchair autonomous navigation.</p