9,260 research outputs found
Solid Rocket Launch Vehicle Explosion Environments
Empirical explosion data from full scale solid rocket launch vehicle accidents and tests were collected from all available literature from the 1950s to the present. In general data included peak blast overpressure, blast impulse, fragment size, fragment speed, and fragment dispersion. Most propellants were 1.1 explosives but a few were 1.3. Oftentimes the data from a single accident was disjointed and/or missing key aspects. Despite this fact, once the data as a whole was digitized, categorized, and plotted clear trends appeared. Particular emphasis was placed on tests or accidents that would be applicable to scenarios from which a crew might need to escape. Therefore, such tests where a large quantity of high explosive was used to initiate the solid rocket explosion were differentiated. Also, high speed ground impacts or tests used to simulate such were also culled. It was found that the explosions from all accidents and applicable tests could be described using only the pressurized gas energy stored in the chamber at the time of failure. Additionally, fragmentation trends were produced. Only one accident mentioned the elusive "small" propellant fragments, but upon further analysis it was found that these were most likely produced as secondary fragments when larger primary fragments impacted the ground. Finally, a brief discussion of how this data is used in a new launch vehicle explosion model for improving crew/payload survival is presented
Patient-reported outcomes measures and patient preferences for minimally invasive glaucoma surgical devices.
BackgroundMany therapeutic options are available to glaucoma patients. One recent therapeutic option is minimally invasive glaucoma surgical (MIGS) devices. It is unclear how patients view different treatments and which patient-reported outcomes would be most relevant in patients with mild to moderate glaucoma. We developed a questionnaire for patients eligible for MIGS devices and a patient preference study to examine the value patients place on certain outcomes associated with glaucoma and its therapies.ObjectivesTo summarize the progress to date.MethodsQuestionnaire development: We drafted the questionnaire items based on input from one physician and four patient focus groups, and a review of the literature. We tested item clarity with six cognitive interviews. These items were further refined. Patient preference study: We identified important benefit and risk outcomes qualitatively using semi-structured, one-on-one interviews with patients who were eligible for MIGS devices. We then prioritized these outcomes quantitatively using best-worst scaling methods.ResultsQuestionnaire testing: Three concepts were deemed relevant for the questionnaire: functional limitations, symptoms, and psychosocial factors. We will evaluate the reliability and validity of the 52-item draft questionnaire in an upcoming field test. Patient preference study: We identified 13 outcomes that participants perceived as important. Outcomes with the largest relative importance weights were "adequate IOP control" and "drive a car during the day."ConclusionsPatients have the potential to steer clinical research towards outcomes that are important to them. Incorporating patients' perspectives into the MIGS device development and evaluation process may expedite innovation and availability of these devices
Configuration of the high‐latitude thermosphere neutral circulation for IMF B y negative and positive
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/94946/1/grl2864.pd
Positron Annihilation in the Galaxy
The 511 keV line from positron annihilation in the Galaxy was the first γ-ray line detected to originate from outside our solar system. Going into the fifth decade since the discovery, the source of positrons is still unconfirmed and remains one of the enduring mysteries in γ-ray astronomy. With a large flux of ∼10−3 γ/cm2/s, after 15 years in operation INTEGRAL/SPI has detected the 511 keV line at >50σ and has performed high-resolution spectral studies which conclude that Galactic positrons predominantly annihilate at low energies in warm phases of the interstellar medium. The results from imaging are less certain, but show a spatial distribution with a strong concentration in the center of the Galaxy. The observed emission from the Galactic disk has low surface brightness and the scale height is poorly constrained, therefore, the shear number of annihilating positrons in our Galaxy is still not well know. Positrons produced in β+-decay of nucleosynthesis products, such as 26Al, can account for some of the annihilation emission in the disk, but the observed spatial distribution, in particular the excess in the Galactic bulge, remains difficult to explain. Additionally, one of the largest uncertainties in these studies is the unknown distance that positrons propagate before annihilation. In this paper, we will summarize the current knowledge base of Galactic positrons, and discuss how next-generation instruments could finally provide the answers.Non peer reviewedFinal Accepted Versio
The Study of TeV Variability and Duty Cycle of Mrk 421 from 3 Years of Observations with the Milagro Observatory
TeV flaring activity with time scales as short as tens of minutes and an
orphan TeV flare have been observed from the blazar Markarian 421 (Mrk 421).
The TeV emission from Mrk 421 is believed to be produced by leptonic
synchrotron self-Compton (SSC) emission. In this scenario, correlations between
the X-ray and the TeV fluxes are expected, TeV orphan flares are hardly
explained and the activity (measured as duty cycle) of the source at TeV
energies is expected to be equal or less than that observed in X-rays if only
SSC is considered. To estimate the TeV duty cycle of Mrk 421 and to establish
limits on its variability at different time scales, we continuously observed
Mrk 421 with the Milagro observatory. Mrk 421 was detected by Milagro with a
statistical significance of 7.1 standard deviations between 2005 September 21
and 2008 March 15. The observed spectrum is consistent with previous
observations by VERITAS. We estimate the duty cycle of Mrk 421 for energies
above 1 TeV for different hypothesis of the baseline flux and for different
flare selections and we compare our results with the X-ray duty cycle estimated
by Resconi et al. 2009. The robustness of the results is discussed.Comment: 27 pages, 6 figures, ApJ accepte
The Study of TeV Variability and the Duty Cycle of Mrk 421 from 3 Yr of Observations with the Milagro Observatory
TeV-flaring activity with timescales as short as tens of minutes and an orphan TeV flare have been observed from the blazar Markarian 421 (Mrk 421). The TeV emission from Mrk 421 is believed to be produced by leptonic synchrotron self-Compton (SSC) emission. In this scenario, correlations between the X-ray and the TeV fluxes are expected, TeV orphan flares are hardly explained, and the activity (measured as duty cycle) of the source at TeV energies is expected to be equal to or less than that observed in X-rays if only SSC is considered. To estimate the TeV duty cycle of Mrk 421 and to establish limits on its variability at different timescales, we continuously observed Mrk 421 with the Milagro observatory. Mrk 421 was detected by Milagro with a statistical significance of 7.1 standard deviations between 2005 September 21 and 2008 March 15. The observed spectrum is consistent with previous observations by VERITAS. We estimate the duty cycle of Mrk 421 for energies above 1 TeV for different hypotheses of the baseline flux and for different flare selections and we compared our results with the X-ray duty cycle estimated by Resconi et al. The robustness of the results is discussed
Effects of a Community-based Lifestyle Intervention on Change in Physical Activity Among Economically Disadvantaged Adults With Prediabetes
Observation and Spectral Measurements of the Crab Nebula with Milagro
The Crab Nebula was detected with the Milagro experiment at a statistical
significance of 17 standard deviations over the lifetime of the experiment. The
experiment was sensitive to approximately 100 GeV - 100 TeV gamma ray air
showers by observing the particle footprint reaching the ground. The fraction
of detectors recording signals from photons at the ground is a suitable proxy
for the energy of the primary particle and has been used to measure the photon
energy spectrum of the Crab Nebula between ~1 and ~100 TeV. The TeV emission is
believed to be caused by inverse-Compton up-scattering scattering of ambient
photons by an energetic electron population. The location of a TeV steepening
or cutoff in the energy spectrum reveals important details about the underlying
electron population. We describe the experiment and the technique for
distinguishing gamma-ray events from the much more-abundant hadronic events. We
describe the calculation of the significance of the excess from the Crab and
how the energy spectrum is fit. The fit is consistent with values measured by
IACTs between 1 and 20 TeV. Fixing the spectral index to values that have been
measured below 1 TeV by IACT experiments (2.4 to 2.6), the fit to the Milagro
data suggests that Crab exhibits a spectral steepening or cutoff between about
20 to 40 TeV.Comment: Submitted to Astrophysical Journa
Edible crabs “Go West”: migrations and incubation cycle of Cancer pagurus revealed by electronic tags
Crustaceans are key components of marine ecosystems which, like other exploited marine taxa, show seasonable patterns of distribution and activity, with consequences for their availability to capture by targeted fisheries. Despite concerns over the sustainability of crab fisheries worldwide, difficulties in observing crabs’ behaviour over their annual cycles, and the timings and durations of reproduction, remain poorly understood. From the release of 128 mature female edible crabs tagged with electronic data storage tags (DSTs), we demonstrate predominantly westward migration in the English Channel. Eastern Channel crabs migrated further than western Channel crabs, while crabs released outside the Channel showed little or no migration. Individual migrations were punctuated by a 7-month hiatus, when crabs remained stationary, coincident with the main period of crab spawning and egg incubation. Incubation commenced earlier in the west, from late October onwards, and brooding locations, determined using tidal geolocation, occurred throughout the species range. With an overall return rate of 34%, our results demonstrate that previous reluctance to tag crabs with relatively high-cost DSTs for fear of loss following moulting is unfounded, and that DSTs can generate precise information with regards life-history metrics that would be unachievable using other conventional means
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