G1.9+0.3 – The New Kid on the Block

https://scholarworks.moreheadstate.edu/student_scholarship_posters/1149/thumbnail.jp

When Social Program Responsibilities Trickle Down: Impacts of Devolution on Local Human Services Provision

The Personal Responsibility and Work Opportunity Reconciliation Act of 1996 (PRWORA) shifted responsibility for public assistance from the federal government to the states. This study examined early impacts of this devolution and related program reductions on local service authorities in Illinois. Based on surveys from 101 large townships responsible for administering General Assistance, medical assistance, and emergency needs programs, we found that 60 percent of these localities experienced increased service demands. These demands not only placed pressure on limited local programming funds, but also transformed local service populations in subtle and unintended ways. Reports of bureaucratic mistreatment and confusion also were common as states implemented PRWORA changes. Local responses to increased service demands were variable, with many localities increasing expenditures but expressing reservations about longer term funding given local tax limits. Follow-up surveys with 40 township officials two years later found that a declining economy and impending Temporary Assistance for Needy Families (TANF) five-year time limits were intensifying township program concerns. The implications of these findings for the development and monitoring of state and local public assistance systems are discussed

Job Stability and Wage Progression Patterns among Early TANF Leavers

This article reports on first-year employment experiences of a randomly selected sample of 213 Illinois TANF leavers. Aggregate employment levels were 70 percent at exit, and leavers typically generated earnings from a single full-time job. However, employment often was unstable, so that only about one-fourth of leavers had the same job both at exit and when interviewed 10-11 months later. Employment instability resulted from the marginal or temporary nature of many jobs, as well as employment barriers such as health problems and lack of day care. Average wage levels easily exceeded the minimum wage and grew during the first year after exit, but nonetheless often were insufficient to provide incomes above the poverty level. The findings underscore the need to develop post-employment service strategies that assist persons in accessing work-related benefits such as child care and Medicaid, as well as improved income support strategies such as expansion of the Earned Income Tax Credit

Expression of complementary RNA from chloroplast transgenes affects editing efficiency of transgene and endogenous chloroplast transcripts

The expression of angiosperm chloroplast genes is modified by C-to-U RNA editing. The mechanism for recognition of the ∼30 C targets of editing is not understood. There is no single consensus sequence surrounding editing sites, though sites can be grouped into small ‘clusters’ of two to five sites exhibiting some sequence similarity. While complementary RNA that guides nucleotides for alteration has been detected in other RNA modification systems, it is not known whether complementary RNA is involved in chloroplast editing site recognition. We investigated the effect of expressing RNA antisense to the sequences −20 to +6 surrounding the RpoB-2 C target of editing, which is a member of a cluster that includes the PsbL-1 and Rps14-1 sites. Previous experiments had shown that chloroplast rpoB transgene transcripts carrying only these 27 nt were edited in vivo at the proper C. Though transcripts carrying sequences −31 to +60 surrounding the RpoB-2 sites were edited in chloroplast transgenic plants, transcripts carrying the −31 to +62 region followed by the 27 nt complementary region were not edited at all. In contrast, a similar construct, in which the C target as well as the preceding and subsequent nucleotides were mismatched within the 27 nt region, was efficiently edited. The presence of any of the four transgenes carrying RpoB-2 sequences in sense and/or antisense orientation resulted in reduced editing at the PsbL-1 site. Chloroplast transgenic plants expressing the three different antisense RNA constructs exhibited abnormal growth and development, though plants expressing the 92 nt sense transcripts were phenotypically normal

Death after smoking of fentanyl, 5F-ADB, 5F-MDMB-P7AICA and other synthetic cannabinoids with a bucket bong

Purpose: We report a case of a polydrug user who consumed various synthetic cannabinoids and fentanyl from a transdermal patch via a bucket bong. Toxicological results from postmortem matrices with special focus on synthetic cannabinoids are discussed in terms of their relevance to the death. Methods: The samples were analyzed by toxicological screening procedures involving immunoassays and gas chromatography–mass spectrometry (GC–MS) as well as quantitative analyses by means of GC–MS and high-performance liquid chromatography–tandem mass spectrometry (LC–MS/MS). Results: At the autopsy, coronary artery disease and signs of liver congestion were noted, in the absence of acute myocardial ischemic changes. Femoral blood concentrations of fentanyl and pregabalin were 14 ng/mL and 3,200 ng/mL, respectively. In addition, 2.7 ng/mL 5F-ADB and 13 ng/mL 5F-MDMB-P7AICA were detected together with relatively low amounts of 5 other synthetic cannabinoids in cardiac blood. A total number of up to 17 synthetic cannabinoids were detected in kidney, liver, urine and hair. Fentanyl and 5F-ADB were also detected in the water of the bucket bong. Conclusions: The cause of death could be attributed to an acute mixed intoxication by fentanyl and 5F-ADB (both Toxicological Significance Score (TSS) = 3) with a contribution of pregabalin and 5F-MDMB-P7AICA (TSS = 2), in a subject suffering from pre-existing heart damage. The most plausible mechanism of death consists in a respiratory depression. This case report demonstrates that use of opioids in combination with synthetic cannabinoids might be particularly dangerous

Comparison of Safety and Efficacy of Insulin Glargine and Neutral Protamine Hagedorn Insulin in Older Adults with Type 2 Diabetes Mellitus: Results from a Pooled Analysis

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90150/1/jgs3773.pd

Contaminated concrete surface layer removal

Equipment is being developed to economically remove contaminated concrete surfaces in nuclear facilities. To be effective this equipment should minimize personnel radiation exposure, minimize the volume of material removed, and perform the operation quickly with the least amount of energy. Several methods for removing concrete surfaces are evaluated for use in decontaminating such facilities. Two unique methods especially suited for decontamination are described: one, the water cannon, is a device that fires a high-velocity jet of fluid causing spallation of the concrete surface; the other, a concrete spaller, is a tool that exerts radial pressure agains the sides of a pre-dilled shallow cylindrical hole causing spallation to occur. Each method includes a means for containing airborne contamination. Results of tests show that these techniques can rapidly and economically remove surfaces, and leave minimal rubble for controlled disposal

The complete integral closure of monoids and domains II

Using geometrical methods we construct primary monoids whose complete integral closure is not completely integrally closed. Such monoids cannot be realized as multiplicative monoids of integral domains with finitely generated groups of divisibility. Complete integral closure, Primary monoids

Preparation of ultralow-friction surface films on vanadium diboride.

In this paper, we present a simple annealing procedure (which we refer to as ''flash-annealing'' because of short duration) that results in the formation of an ultralow friction surface film on vanadium diboride (VB{sub 2}) surfaces. This annealing is done in a box furnace at 800 C for a period of 5 min. During annealing, the exposed surface of the VB{sub 2} undergoes oxidation and forms a layer of boron oxide (B{sub 2}O{sub 3}). In open air, the B{sub 2}O{sub 3} layer reacts spontaneously with moisture and forms a boric acid (H{sub 3}BO{sub 3}) film. The friction coefficient of a 440C steel pin against this H{sub 3}BO{sub 3} film is {approx}0.05, compared to 0.8 against the as-received VB{sub 2}. Based on Raman spectroscopy and electron microscopy studies, we elucidate the ultralow friction mechanism of the flash-annealed VB{sub 2} surfaces