Quantitative Determination of Natriuretic Peptides in Human Biological Samples with a Bioassay Using Cultured Cells

Peer Reviewe

Global irrigation water demand: Variability and uncertainties arising from agricultural and climate data sets

Agricultural water use accounts for around 70% of the total water that is withdrawn from surface water and groundwater. We use a new, gridded, global-scale water balance model to estimate interannual variability in global irrigation water demand arising from climate data sets and uncertainties arising from agricultural and climate data sets. We used contemporary maps of irrigation and crop distribution, and so do not account for variability or trends in irrigation area or cropping. We used two different global maps of irrigation and two different reconstructions of daily weather 1963–2002. Simulated global irrigation water demand varied by ∼30%, depending on irrigation map or weather data. The combined effect of irrigation map and weather data generated a global irrigation water use range of 2200 to 3800 km3 a−1. Weather driven variability in global irrigation was generally less than ±300 km3 a−1, globally (\u3c∼10%), but could be as large as ±70% at the national scale

The significance of local water resources captured in small reservoirs for crop production – A global-scale analysis

Rainwater harvesting, broadly defined as the collection and storage of surface runoff, has a long history in supplying water for agricultural purposes. Despite its significance, rainwater harvesting in small reservoirs has previously been overlooked in large-scale assessments of agricultural water supply and demand. We used a macroscale hydrological model, observed climate data and other physical datasets to explore the potential role of small, localized rainwater harvesting systems in supplying water for irrigated areas. We first estimated the potential contribution of local water harvesting to supply currently irrigated areas. We then explored the potential of supplemental irrigation applied to all cropland areas to increase crop evapotranspiration (or green water flow), using locally stored surface runoff in small reservoirs for different scenarios of installed reservoir capacity. The estimated increase in green water flow varied between 623 and 1122 km3 a1 . We assessed the implications of this increase in green water flows for cereal production by assuming a constant crop water productivity in areas where current levels of crop yield are below global averages. Globally, the supplemental irrigation of existing cropland areas could increase cereal production by 35% for a medium variant of reservoir capacity, with large potential increases in Africa and Asia. As small reservoirs can significantly impact the hydrological regime of river basins, we also assessed the impacts of small reservoirs on downstream river flow and quantified evaporation losses from small reservoirs

Influence of Food Intake on Concentrations of Plasma Catecholamines and Cortisol

Peer Reviewe

Berechnung der Parameter des Säure-Basen-Haushaltes mit Hilfe eines Kleincomputers

Peer Reviewe

Micrometre‐sized porous polymer beads as heterogeneous molecular catalysts

Porous polymers have great potential as versatile, chemically stable catalyst supports. Yet, shaping of the resulting powders remains a challenge. Here, we demonstrate the use of suspension polymerisation to design micrometre-sized porous polymers beads containing metal binding sites. The good accessibility of the binding sites ensures high catalytic activity, which is demonstrated for two model reactions: photochemical CO2 reduction and transfer hydrogenation of aromatic ketones. Importantly, the shaping of the host material does not affect the catalytic activity of the active site

Abhängigkeit der Konzentrationen von Kreatinin und Harnstoff im Serum von der Tageszeit bei normaler und eingeschränkter Nierenfunktion

Peer Reviewe

PCR-GLOBWB 2: a 5 arcmin global hydrological and water resources model

We present PCR-GLOBWB 2, a global hydrology and water resources model. Compared to previous versions of PCR-GLOBWB, this version fully integrates water use. Sector-specific water demand, groundwater and surface water withdrawal, water consumption, and return flows are dynamically calculated at every time step and interact directly with the simulated hydrology. PCR-GLOBWB 2 has been fully rewritten in Python and PCRaster Python and has a modular structure, allowing easier replacement, maintenance, and development of model components. PCR-GLOBWB 2 has been implemented at 5 arcmin resolution, but a version parameterized at 30 arcmin resolution is also available. Both versions are available as open-source codes on https://github.com/UU-Hydro/PCR-GLOBWB_model (Sutanudjaja et al., 2017a). PCR-GLOBWB 2 has its own routines for groundwater dynamics and surface water routing. These relatively simple routines can alternatively be replaced by dynamically coupling PCR-GLOBWB 2 to a global two-layer groundwater model and 1-D–2-D hydrodynamic models. Here, we describe the main components of the model, compare results of the 30 and 5 arcmin versions, and evaluate their model performance using Global Runoff Data Centre discharge data. Results show that model performance of the 5 arcmin version is notably better than that of the 30 arcmin version. Furthermore, we compare simulated time series of total water storage (TWS) of the 5 arcmin model with those observed with GRACE, showing similar negative trends in areas of prevalent groundwater depletion. Also, we find that simulated total water withdrawal matches reasonably well with reported water withdrawal from AQUASTAT, while water withdrawal by source and sector provide mixed results

Risks of pregnancy and birth in obese primiparous women: an analysis of German perinatal statistics

PURPOSE: To compare risks of pregnancy and birth in obese (body mass index, BMI ≥ 30) and normal weight women (BMI 18.5–24.99) giving birth to their first child. METHODS: We analysed data of 243,571 pregnancies in primiparous women from the German perinatal statistics of 1998–2000. We calculated odds ratios (ORs) with 95% confidence intervals (CIs) for selected pregnancy and birth risks. ORs were adjusted for the confounding factors age, smoking status, single mother status, and maternal education. RESULTS: Obesity during pregnancy is common in primiparous women (n = 19,130; 7.9% of all cases) and it is significantly associated with a number of risks of pregnancy and birth, including diabetes [OR 3.71 (95% CI 2.93; 4.71); p < 0.001], hypertension [OR 8.44 (7.91; 9.00); p < 0.001], preecalmpsia/eclampsia [OR 6.72 (6.30; 7.17); p < 0.001], intraamniotic infection [OR 2.33 (2.05; 2.64); p < 0.001], birth weight ≥4,000 g [OR 2.16 (2.05; 2.28); p < 0.001], and an increased rate of Caesarean section [OR 2.23 (2.15; 2.30); p < 0.001]. Some risks were less frequent in the obese such as cervical incompetence [OR 0.55 (0.48; 0.63); p < 0.001] and preterm labour [OR 0.47 (0.43; 0.51); p < 0.001]. CONCLUSIONS: Obesity during pregnancy is an important clinical problem in primiparous women because it is common and it is associated with a number of risks of pregnancy and birth. Because of these increased risks, obese women need special attention clinically during the course of their first pregnancy. Weight reduction before the first pregnancy is generally indicated in obese women to prevent the above-mentioned complications of pregnancy and birth

Ferromagnetic resonances in single-crystal yttrium iron garnet nanofilms fabricated by metal-organic decomposition

Tunable microwave and millimeter wave oscillators and bandpass filters with ultra-low phase noise play a critical role in electronic devices, including wireless communication, microelectronics, and quantum computing. Magnetic materials, such as yttrium iron garnet (YIG), possess ultra-low phase noise and a ferromagnetic resonance tunable up to tens of gigahertz. Here, we report structural and magnetic properties of single-crystal 60 and 130 nm-thick YIG films prepared by metal-organic decomposition epitaxy. These films, consisting of multiple homoepitaxially grown monolayers, are atomically flat and possess magnetic properties similar to those grown with liquid-phase epitaxy, pulsed laser deposition, and sputtering. Our approach does not involve expensive high-vacuum deposition systems and is a true low-cost alternative to current commercial techniques that have the potential to transform the industry