1,139 research outputs found
Working memory learning method and astrocytes number in different subfields of rat's Hippocampus
The aim of this study was evaluation of the astrocytes number in different subfields of rat's Hippocampus after spatial learning with usage of Morris Water Maze technique and working memory method. In this study, between 2005-2006 years in Pasteur institute of Iran-Tehran and histological department of Gorgan University with usage of Morris Water Maze and working memory technique, we used 14 male albino wistar rats. Seventh rats were in control group and 7 rats in working memory group. After histological preparation, the slides were stained with PTAH staining for showing the Astrocytes. Present results showed significant difference in astrocytes number in CA1, CA2 and CA3 areas of hippocampus between control and reference memory group. The number of astrocytes is increased in working memory group. Then we divided the hippocampus to three parts: Anterior, middle and posterior and with compare of different area (CA1, CA2 and CA3) of hippocampus, we found that the differences between Anterior-middle and Middle-Posterior of CA1 and CA2 area of hippocampus were significant, whereas the difference between Anterior-Posterior parts was not significant in CA1 and CA2 areas. In CA3 area, the difference between Anterior-Middle and Anterior-Posterior parts was significant, whereas the difference between middle and posterior parts was not significant. We concluded that the number of astrocytes increased due to spatial learning and working memory technique. © 2008 Science Publications
Fluctuation dynamo and turbulent induction at low magnetic Prandtl numbers
This paper is a detailed report on a programme of simulations used to settle
a long-standing issue in the dynamo theory and demonstrate that the fluctuation
dynamo exists in the limit of large magnetic Reynolds number Rm>>1 and small
magnetic Prandtl number Pm<<1. The dependence of the critical Rm_c vs. the
hydrodynamic Reynolds number Re is obtained for 1<Re<6700. In the limit Pm<<1,
Rm_c is ~3 times larger than for Pm>1. The stability curve Rm_c(Re) (and, it is
argued, the nature of the dynamo) is substantially different from the case of
the simulations and liquid-metal experiments with a mean flow. It is not as yet
possible to determine numerically whether the growth rate is ~Rm^{1/2} in the
limit Re>>Rm>>1, as should be the case if the dynamo is driven by the
inertial-range motions. The magnetic-energy spectrum in the low-Pm regime is
qualitatively different from the Pm>1 case and appears to develop a negative
spectral slope, although current resolutions are insufficient to determine its
asymptotic form. At 1<Rm<Rm_c, the magnetic fluctuations induced via the
tangling by turbulence of a weak mean field are investigated and the
possibility of a k^{-1} spectrum above the resistive scale is examined. At low
Rm<1, the induced fluctuations are well described by the quasistatic
approximation; the k^{-11/3} spectrum is confirmed for the first time in direct
numerical simulations.Comment: IoP latex, 27 pages, 25 figures, 3 tables. Accepted by New J. Physic
Identification of fungal pathogens to control postharvest passion fruit (Passiflora edulis) decays and multi-omics comparative pathway analysis reveals purple is more resistant to pathogens than a yellow cultivar
Production of passion fruit (Passiflora edulis) is restricted by postharvest decay, which limits the storage period. We isolated, identified, and characterized fungal pathogens causing decay in two passion fruit cultivars during two fruit seasons in China. Morphological characteristics and nucleotide sequences of ITS-rDNA regions identified eighteen isolates, which were pathogenic on yellow and purple fruit. Fusarium kyushuense, Fusarium concentricum, Colletotrichum truncatum, and Alternaria alternata were the most aggressive species. Visible inspections and comparative analysis of the disease incidences demonstrated that wounded and non-wounded yellow fruit were more susceptible to the pathogens than the purple fruit. Purple cultivar showed higher expression levels of defense-related genes through expression and metabolic profiling, as well as significantly higher levels of their biosynthesis pathways. We also found fungi with potential beneficial features for the quality of fruits. Our transcriptomic and metabolomics data provide a basis to identify potential targets to improve the pathogen resistance of the susceptible yellow cultivar. The identified fungi and affected features of the fruit of both cultivars provide important information for the control of pathogens in passion fruit industry and postharvest storage
The Nexus of Political Violence and Economic Deprivation: Pakistani Migrants Disrupt the Refugee / Migrant Dichotomy
There have been discussions about how the labels “forced migrants,” related to political violence, and “voluntary migrants,” associated with economic factors, cannot be understood in categorical ways. However, there has been less focus on the specificities of the asylum-migrant nexus from the perspective of migrants. This essay discusses how such factors intersect as understood by Pakistani migrants residing in Germany. Through enacting a critical view of Pakistan, the migrants demonstrate how aspects of corruption, economic deprivation, and political violence come to intersect so that is becomes impossible to classify asylum seekers in binary/dichotomous ways
Combination of glycosphingosomes and liposomal doxorubicin shows increased activity against dimethyl-α-benzanthracene-induced fibrosarcoma in mice
A new hybrid multilevel thyristor-based DC-DC converter
The rapid growth in HVDC grids is becoming inevitable for long-distance power transmission. Therefore, the idea of interconnection between the point-to-point links becomes essential. However, these point-to-point connections face several challenges such as the requirement of DC fault blocking capability, interfacing of different grounding schemes, offering multi-vendor interoperability, and difficulty to achieve high DC voltage stepping. DC-DC converters are considered the optimum solution to tackle these challenges in DC grids interconnection. In this paper, a new hybrid modular DC-DC converter is proposed that achieves a low number of semiconductors, low losses, and cost in comparison to other DC-DC converters due to the utilization of thyristors. The new DC-DC converter consists of two hybrid MMC bridges connected through an isolating transformer. Each MMC bridge is comprised of half bridge submodules and bidirectional thyristors. Detailed mathematical analysis, design, and control are illustrated. A comparison is carried out between different topologies in terms of semiconductor count, power loss, and cost. Also, both simulation model and experimental test rig are built to validate the proposed hybrid modular DC-DC converter under different scenarios. Finally, another variant of the hybrid-thyristor based converter (version two) is proposed for multiport DC-Hub application to achieve DC fault blocking without turning off all connected bridges
Three dysregulated miRNAs control kallikrein 10 expression and cell proliferation in ovarian cancer
Bihelical Magnetic Relaxation and Large Scale Magnetic Field Growth
A unified, three-scale system of equations accommodating nonlinear velocity
driven helical dynamos, as well as time-dependent relaxation of magnetically
dominated unihelical or bihelical systems is derived and solved herein. When
opposite magnetic helicities of equal magnitude are injected on the
intermediate and small scales, the large scale magnetic helicity grows
kinematically (independent of the magnetic Reynolds number) to equal that on
the intermediate scale. For both free and driven relaxation large scale fields
are rapidly produced. Subsequently, a dissipation-limited dynamo, driven by
growth of small scale kinetic helicity, further amplifies the large scale
field. The results are important for astrophysical coronae fed with bihelical
structures by dynamos in their host rotators. The large scale for the rotator
corresponds to the intermediate scale for the corona. That bihelical magnetic
relaxation can produce global scale fields may help to explain the formation of
astrophysical coronal holes and magnetohydrodynamic outflows.Comment: LaTeX, 29 pages including figures, version in press, Physics of
Plasma
The Impact of ACE Gene Variants on Acute-Phase Reactants in Children with Rheumatic Heart Disease
Rheumatic heart disease (RHD) is the most important sequela of upper respiratory group A Streptococcus (GAS) infection. The role of the common angiotensin-converting enzyme (ACE) insertion/deletion (I/D) variant in the disease and its subtypes remains uncertain. The acute-phase reactants (APRs) C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) form part of the Jones criteria for diagnosing RHD, and genetic factors are known to influence baseline CRP and ESR levels. Therefore, here, we investigated the relationship between the ACE I/D polymorphism and APR levels in RHD. A total of 268 individuals were recruited, including 123 RHD patients and 198 healthy controls. There was a trend toward a higher D allele frequency in RHD patients. The ACE I/D polymorphism genotype frequency and DD+ID allelic carriage were significantly associated with a high APR level (p = 0.04 and p = 0.02, respectively). These results highlight the importance of ACE I/D polymorphisms in RHD for disease stratification, but not for disease predisposition. Further studies in larger cohorts and different populations are now required to confirm this association and to explore the mechanism of this effect.This publication was supported by Qatar University, internal grant nos. QUCP-CHS-2022-551 and QUST-1-CHS-2023-923. The findings presented herein are solely the responsibility of the authors.Scopu
Dynamics & Predictions in the Co-Event Interpretation
Sorkin has introduced a new, observer independent, interpretation of quantum
mechanics that can give a successful realist account of the 'quantum
microworld' as well as explaining how classicality emerges at the level of
observable events for a range of systems including single time 'Copenhagen
measurements'. This 'co-event interpretation' presents us with a new ontology,
in which a single 'co-event' is real. A new ontology necessitates a review of
the dynamical & predictive mechanism of a theory, and in this paper we begin
the process by exploring means of expressing the dynamical and predictive
content of histories theories in terms of co-events.Comment: 35 pages. Revised after refereein
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