732 research outputs found

    The effect of individual counseling, line follow-up, and free nicotine replacement therapy on smoking cessation in the samples of Iranian smokers: Examination of transtheoretical model

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    Background: According to transtheoretical model(TTM), Stage matched interventions are more effective in quitting. The objective of current study was to investigate the effect of individual counseling, line follow-up, and free nicotine replacement therapy(NRT) on smoking cessation in smokers who are in preparation stage of smoking. Materials and Methods: In a randomized clinical trial design, through sending the short message system, potential participants in preparation stage of smoking were recruited and divided into control(n=60)and treatment(n=50) groups. The treatment group received an in-person counseling, line follow-up, and free NRT. TTM variables trend; pros and cons of smoking, behavioral and experiential processes, temptation, were assessed at baseline, 3 and 6months follow-up along with point prevalence and continuous abstinence. Results: Continuous abstinence at 6-month follow-up were 3.3%(n=2) in control group and 46%(n=23) in the treatment group(x 2 = 34.041, P < 0.001). Time � group analyses indicated that except cons of smoking (P > 0.05), all TTM constructs had significantly changed; temptation(F=36.864, P<0.001), pros (F=12.172, P<0.001), experiential processes(F=3.377, P<0.001), and behavioral processes(F=11.131, P<0.001). Conclusion: Interventions based on TTM variables increased the quite rate in prepared and motivated people. Our findings suggest that interventions through individual counseling along with free NRT and line follow-up in people who prepare for quitting are beneficial for our country

    Hanging bladder calculi secondary to misplaced surgical suture

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    Bladder calculi, a rare condition in the pediatric population, occur most commonly as a result of either migration from the kidney or urinary stasis in the bladder. We report the case of a 3-year-old boy with recurrent urinary tract infections (UTI) secondary to bladder calculi formation on the sutures from a previous herniorrhaphy.A 3-year-old boy with previous history of herniorrhaphy presented with recurrent episodes of urinary tract infection, resistant to antibiotic therapy. Physical examination was unremarkable. Ultrasonography (US) showed an echogenic fixed intra-luminal lesion in the bladder. Cystoscopic evaluation was performed and confirmed presence of calculi forming around several permanent silk sutures fixed to the bladder wall. The patient undergone cystotomy and the calculi were resected. The stone analysis revealed 80 uric acid calculi. The final diagnosis was of bladder calculi due to remnant suture from past herniorrhaphy. © 2015, Tehran University of Medical Sciences and Iranian Society of Radiology

    Eigenstates Transition without Undergoing an Adiabatic Process

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    We introduce a class of non-Hermitian Hamiltonians that offers a dynamical approach to a shortcut to adiabaticity (DASA). In particular, in our proposed 2 × 2 Hamiltonians, one eigenvalue is absolutely real and the other one is complex. This specific form of eigenvalues helps us to exponentially decay the population in an undesired eigenfunction or amplify the population in the desired state while keeping the probability amplitude in the other eigenfunction conserved. This provides us with a powerful method to have a diabatic process with the same outcome as its corresponding adiabatic process. In contrast to standard shortcuts to adiabaticity, our Hamiltonians have a much simpler form with a lower thermodynamic cost. Furthermore, we show that DASA can be extended to higher dimensions using the parameters associated with our 2 × 2 Hamiltonians. Our proposed Hamiltonians not only have application in DASA but also can be used for tunable mode selection and filtering in acoustics, electronics, and optics

    Food irradiation: Applications, public acceptance and global trade

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    Food irradiation is the treatment of food products by a definite kind of energy. The process involves exposing the packed or bulked food to the rays of the sun. Food irradiation processing that entails combating post-harvest losses, curtailing food-borne disease and overcoming quarantine barriers has been pursued since the mid-50s. The scientific basis and technological adaptation of the process have been well established more than any other post-harvest food processing techniques. In 1981, the FAO/IAEA/WHO Joint Expert Committees on the wholesomeness of irradiated food (JECFI) concluded, “the irradiation of any food commodity up to an overall average dose of 10 KGy presents notoxicological hazard”. The benefits of irradiation technology in addressing post-harvest food problems are, in some cases, unique and can improve the quality of a number of food products by eliminating the risk of pathogenic contaminants. The potential of this technology has been well perceived in recent years in the wake of food-borne disease caused by pathogenic organisms. In fact, many parts of the world are considering food irradiation as a technological saviour in finding a suitable solution for the problems caused by pathogens in food. Irradiation can be regarded as a useful tool to attain food security in the 21st century. Many consumers have misconceptions about the technology and suppose that it makes food radioactive. But, when the method is explained to them they become normally more in favor of it. Over 50 countries have regulatory approvals in place for irradiation of one or more food products. 30 countries are practically applying this technology for a number of food items

    Molecular diversity of Symbiodinium spp. within six coral species in Larak Island, the Persian Gulf

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    Reef-building coral harbor communities of photosynthetic taxa of the genus Symbiodinium (zooxanthellae). The genus Symbiodinium is currently classified into nine genetic clades (A–I). Various corals harbor different Symbiodinium clades; some show specificity to a single strain. Coral and their zooxanthellae are sensitive to environmental stresses. In the Persian Gulf, coral reefs are subject to harsh environmental conditions including extreme temperatures and high salinity. This is the first study to use clade specific primers to clarify the diversity of Symbiodinium in each coral species of Larak Island. For this purpose six coral species were collected at two different locations in Larak Island. After DNA extraction, PCR amplification was performed using clade specific primers. The results showed that multiple Symbiodinium clades are hosted by most coral species. In addition, among thirteen obtained Symbiodinium sequences, the frequency of either tree [sic] clades, A, C and D was almost the same. Corals species may contain different clades of Symbiodinium depending on the region and on the tolerance characteristics of each clade. Thus, knowledge of zooxanthellae diversity associated with scleractinian can contribute to a better understanding of the sensitivity of corals to environmental conditions

    Evaluation of gamma irradiation effect and Pseudomonas flourescens against Penicillium expansum

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    Antagonistic effect of Pseudomonas fluorescens and influence of gamma irradiation on the development of Penicillium expansum, the causal agent of postharvest disease on apple fruit was studied. P. fluorescens was originally isolated from rhizosphere of the apple trees. Suspension of P. fluorescens and P. expansum were mixed in test tubes in proportions of 1:5, 2:5, 3:5 and 4:5 (V/V). The inhibitory effect depended on the proportion of the bacterium to the fungus in the mixture. The best inhibition was observed after 48 h at the ratio of 3:5. Gamma irradiation above 3 KGy completelyinhibited mycelial growth, while the highest dose around 600 Gy mostly killed P. expansum spores. Our experiment demonstrates that the combination of gamma irradiation and P. fluorescens was more effective in reducing P. expansum growth, than either treatment alone and that the integration of irradiation and antagonist treatments can be more effective. The results of this study show that improved control by irradiation at labeled dose in combination with antagonist could allow direct incorporation of the biocontrol agent. Thus, the combination of the P. fluorescens with gamma irradiation showed an impressive effect on increasing applied range of irradiation for postharvest control by decreasing of dose rate.Key words: Antagonist treatment, gamma irradiation, Penicillium expansum, Pseudomonas fluorescens, postharvest disease

    A dynamic and context-aware semantic mediation service for discovering and fusion of heterogeneous sensor data

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    Sensors play an increasingly critical role in capturing and distributing observations of phenomena in our environment. The vision of the semantic sensor web is to enable the interoperability of various applications that use sensor data provided by semantically heterogeneous sensor services. However, several challenges still need to be addressed to achieve this vision. More particularly, mechanisms that can support context-aware semantic mapping and that can adapt to the dynamic metadata of sensors are required. Semantic mapping for the sensor web is required to support sensor data fusion, sensor data discovery and retrieval, and automatic semantic annotation, to name only a few tasks. This paper presents a context-aware ontology-based semantic mediation service for heterogeneous sensor services. The semantic mediation service is context-aware and dynamic because it takes into account the real-time variability of thematic, spatial, and temporal elements that describe sensor data in different contexts. The semantic mediation service integrates rule-based reasoning to support the resolution of semantic heterogeneities. An application scenario is presented showing how the semantic mediation service can improve sensor data interpretation, reuse, and sharing in static and dynamic settings

    Induced spermiation of rainbow trout, Oncorhynchus mykiss, using a GnRh analogue

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    In this study, the benefits of using the first Iranian made GnRHa[D-Ala6 des Gly10] mGnRH ethylamide, to induce spermiation in male rainbow trout, Oncorhynchus mykiss, were evaluated, In addition, its effect on acceleration and synchronization, quality and quantity of milt and the plasma Testosterone (T) fluctuations were examined. For these purposes, 40 non-spermiating male rainbow trouts were injected with a mammalian gonadotropin releasing hormone analog (GnRHa) preparations of 0 (control), 30, 40 and 80 μg/kg B.W. or vehicle (propylene glycol). Spermiation was very synchronous and accelerated in treated groups. Six days after first injection, the cumulative spermiation rates reached respectively 40, 49 and 79% in injected groups (i.e. 30 to 80 μg/kg B.W.) while none of the control fish was spermiated. GnRHa injections advanced spermiation and reduced the average time to spermiation from 16 3.67 days for control group to 14.3± 2.2, 9.2 ±0.75 and 6.6± 0.29 days for treated groups, respectively (p0.05). Circulating levels of testosterone (T) prior to the GnRHa treatment were relatively low in all groups. Treatment with GnRHa induced significant increase in plasma T after 12 h, increasing it to 43.43±5.82, 38.66±5.63, 39.72±5.07 ng/ml in groups 2 to 4, respectively, which were higher than T levels for control (i.e. 24.58±7.13 ng/ml) p<0.05. These levels remained high up until 48 h in treated groups; but after this time, T levels reduced to the basal levels of time 0, except in 4 which had received its second GnRHa injection at time 48

    Impact of Health Literacy, Self-efficacy, and Outcome Expectations on Adherence to Self-care Behaviors in Iranians with Type 2 Diabetes.

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    OBJECTIVES: Diabetic patients with higher health literacy (HL) may feel more confident in their ability to perform self-care behaviors and may have strong beliefs that diabetes-related behaviors will lead to specific outcomes. Our study aimed to document the relationships between HL, self-efficacy, outcome expectations, and diabetes self-care of patients with type 2 diabetes mellitus (T2DM) in Iran. METHODS: We conducted a cross-sectional observational study of 187 patients with T2DM. Participants completed the Functional Communicative and Critical Health Literacy scale, the Summary of Diabetes Self-Care Activities, the Diabetes Management Self-Efficacy Scale, Outcome Expectations Questionnaire, and a demographic questionnaire. RESULTS: Participants who received diabetes education (t = 5.79, p<0.001) and were married (F = 3.04, p<0.050) had better diabetes self-care behavior. There was a significant positive correlation between self-care behaviors and communicative HL (r = 0.455, p<0.010), critical HL (r = 0.297, p<0.010), self-efficacy (r = 0.512, p<0.010) and outcome expectations (r = 0.387, p<0.010). Diabetes education and marital status accounted for 16.9% of the variance in diabetes self-care. Self-efficacy, outcome expectations, communicative, and critical HL explained 28.0%, 1.5%, 3.7%, and 1.4% of the variance, respectively. CONCLUSIONS: This study revealed that the potential impact of self-efficacy, outcome expectations, communicative, and critical HL should be considered in the education program for patients with diabetes. We found self-efficacy to be the most important predictor of diabetes self-care. Therefore, the use of self-efficacy theory when designing patient education interventions could enhance diabetes self-care. It is essential that health care providers assess patient's HL levels to tailor health-related information specific to a domain of HL. This would fully inform patients and promote empowerment rather than simple compliance

    Entropic forces drive self-organization and membrane fusion by SNARE proteins

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    SNARE proteins are the core of the cell’s fusion machinery and mediate virtually all known intracellular membrane fusion reactions on which exocytosis and trafficking depend. Fusion is catalyzed when vesicle-associated v-SNAREs form trans-SNARE complexes (“SNAREpins”) with target membrane-associated t-SNAREs, a zippering-like process releasing ∼65 kT per SNAREpin. Fusion requires several SNAREpins, but how they cooperate is unknown and reports of the number required vary widely. To capture the collective behavior on the long timescales of fusion, we developed a highly coarse-grained model that retains key biophysical SNARE properties such as the zippering energy landscape and the surface charge distribution. In simulations the ∼65-kT zippering energy was almost entirely dissipated, with fully assembled SNARE motifs but uncomplexed linker domains. The SNAREpins self-organized into a circular cluster at the fusion site, driven by entropic forces that originate in steric–electrostatic interactions among SNAREpins and membranes. Cooperative entropic forces expanded the cluster and pulled the membranes together at the center point with high force. We find that there is no critical number of SNAREs required for fusion, but instead the fusion rate increases rapidly with the number of SNAREpins due to increasing entropic forces. We hypothesize that this principle finds physiological use to boost fusion rates to meet the demanding timescales of neurotransmission, exploiting the large number of v-SNAREs available in synaptic vesicles. Once in an unfettered cluster, we estimate ≥15 SNAREpins are required for fusion within the ∼1-ms timescale of neurotransmitter release
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