Educating for Entrepreneurial Leadership: From Didacticism to Co-creation

Entrepreneurial leadership promotes organisational competitive advantage and innovation resulting in increased attention on entrepreneurial leadership development. Many higher education institutions (HEIs) claim to develop entrepreneurial leaders. However, knowledge of how to facilitate entrepreneurial leadership development is limited, the effectiveness of development practices is contestable, and current understanding of the phenomenon is mostly conceptual. We address this void by exploring educators’ perspectives of entrepreneurial leadership development and consider how the phenomenon is facilitated. We employ Interpretative Phenomenological Analysis (IPA) as our research methodology and analyse the data following IPA data analysis guidance. Findings signify the importance of placing strong emphasis on co-creating education experience with wider stakeholder involvement, thereby forming an entrepreneurial community which works collectively over the longer-term to facilitate entrepreneurial leadership development. The findings also reveal the pedagogic significance of facilitating supportive learning conditions and ‘handholding,’ a broader form of support which contradicts the established notion of ‘independent learners’ thereby challenging current ontologies around ‘student support’ when facilitating entrepreneurial leadership development

Coexistence of supravalvular aortic stenosis and osteogenesis imperfecta.

A 54 year old woman was admitted for cardiac catheterisation. She had-been attending the outpatient clinic since 1975, with regular review. She had diagnoses of type I osteogenesis imperfecta, and of supravalvular aortic stenosis. Osteogenesis imperfecta was diagnosed in early life on clinical grounds including the presence of blue sclerae and the occurrence of several bone fractures secondary to minimal trauma. A number of family members have been diagnosed with the same condition (figure 1-family pedigree). The supravalvular aortic stenosis was not diagnosed until later. She was initially referred to the cardiology clinic for further evaluation following the discovery of a systolic murmu

IDE spatio-temporal impact fluxes and high time-resolution studies of multi-impact events and long-lived debris clouds

The purpose of the Interplanetary Dust Experiment (IDE) on the Long Duration Exposure Facility (LDEF) was to sample the cosmic dust environment and to use the spatio-temporal aspect of the experiment to distinguish between the various components of the environment: zodiacal cloud, beta meteoroids, meteor streams, interstellar dust, and orbital debris. It was found that the introduction of precise time and even rudimentary directionality as co-lateral observables in sampling the particulate environment in near-Earth space produces an enormous qualitative improvement in the information content of the impact data. The orbital debris population is extremely clumpy, being dominated by persistent clouds in which the fluxes may rise orders of magnitude above the background. The IDE data suggest a strategy to minimize the damage to sensitive spacecraft components, using the observed characteristics of cloud encounters

Enhanced transport at high plasma β\beta and sub-threshold kinetic ballooning modes in Wendelstein 7-X

The effect of plasma pressure $\beta$ on ion-temperature-gradient-driven (ITG) turbulence is studied in the Wendelstein 7-X (W7-X) stellarator, showing that subdominant kinetic ballooning modes (KBMs) are unstable well below the ideal MHD threshold and get strongly excited in the quasi-stationary state. By zonal-flow erosion, these highly non-ideal KBMs affect ITG saturation and thereby enable higher heat fluxes. Controlling these KBMs will be essential in order to allow W7-X and future stellarators to achieve maximum performance.Comment: 16 pages, 5 figure

Living on the Margin in the Anthropocene: Engagement Arenas for Sustainability Research and Action at the Ocean-Land Interface

The advent of the Anthropocene underscores the need to develop and implement transformative governance strategies that safeguard the Earth\u27s life-support systems, most critically at the ocean-land interface - the Margin. The seaward realm of the Margin is the new frontier for resource exploitation and colonization to meet the needs of coastal nations and humanity overall. Here, we spotlight the pivotal role of the Margin for planetary resilience and sustainability, highlight priority issues, and outline a research strategy which aims to: (a) better understand Margin social-ecological systems; (b) guide sustainable development of Margin resources; (c) design governance regimes to reverse unsustainable practices; (d) facilitate equitable sharing of Margin resources; and (e) evaluate alternative research approaches and partnerships that address major Margin challenges. © 2015 The Authors

Dynamics of N removal over annual time periods in a suburban river network

Author Posting. © American Geophysical Union, 2008. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research 113 (2008): G03038, doi:10.1029/2007JG000660.River systems are dynamic, highly connected water transfer networks that integrate a wide range of physical and biological processes. We used a river network nitrogen (N) removal model with daily temporal resolution to evaluate how elevated N inputs, saturation of the denitrification and total nitrate removal processes, and hydrologic conditions interact to determine the amount, timing and distribution of N removal in the fifth-order river network of a suburban 400 km2 basin. Denitrification parameters were based on results from whole reach 15NO3 tracer additions. The model predicted that between 15 and 33% of dissolved inorganic nitrogen (DIN) inputs were denitrified annually by the river system. Removal approached 100% during low flow periods, even with the relatively low and saturating uptake velocities typical of surface water denitrification. Annual removal percentages were moderate because most N inputs occurred during high flow periods when hydraulic conditions and temperatures are less favorable for removal by channel processes. Nevertheless, the percentage of annual removal occurring during above average flow periods was similar to that during low flow periods. Predicted river network removal proportions are most sensitive to loading rates, spatial heterogeneity of inputs, and the form of the removal process equation during typical base flow conditions. However, comparison with observations indicates that removal by the river network is higher than predicted by the model at moderately high flows, suggesting additional removal processes are important at these times. Further increases in N input to the network will lead to disproportionate increases in N exports due to the limits imposed by process saturation.This work was funded by NSF-DEB- 0614282, NSF-OCE-9726921, NSF-DEB-0111410, and NSF-BCS- 0709685

Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 h fast provides evidence of effects on genes regulating inflammation, apoptosis and energy metabolism.

There is growing interest in the potential health benefits of diets that involve regular periods of fasting. While animal studies have provided compelling evidence that feeding patterns such as alternate-day fasting can increase longevity and reduce incidence of many chronic diseases, the evidence from human studies is much more limited and equivocal. Additionally, although several candidate processes have been proposed to contribute to the health benefits observed in animals, the precise molecular mechanisms responsible remain to be elucidated. The study described here examined the effects of an extended fast on gene transcript profiles in peripheral blood mononuclear cells from ten apparently healthy subjects, comparing transcript profiles after an overnight fast, sampled on four occasions at weekly intervals, with those observed on a single occasion after a further 24 h of fasting. Analysis of the overnight fasted data revealed marked inter-individual differences, some of which were associated with parameters such as gender and subject body mass. For example, a striking positive association between body mass index and the expression of genes regulated by type 1 interferon was observed. Relatively subtle changes were observed following the extended fast. Nonetheless, the pattern of changes was consistent with stimulation of fatty acid oxidation, alterations in cell cycling and apoptosis and decreased expression of key pro-inflammatory genes. Stimulation of fatty acid oxidation is an expected response, most likely in all tissues, to fasting. The other processes highlighted provide indications of potential mechanisms that could contribute to the putative beneficial effects of intermittent fasting in humans