432 research outputs found
Evaluación y transferencia de tecnología para el manejo integrado del cultivo de fríjol en el oriente antioqueño.
En el oriente Antioqueño, los productores de fríjol, a pesar de tener una trayectoria de muchos años en el cultivo, se ven enfrentados a serios problemas, entre los cuales se destacan la alta incidencia de enfermedades y plagas cuyo manejo es deficiente y trae consecuencias negativas como los altos costos de producción. Con el propósito de evaluar la participación delos agricultores los principales componentes del manejo integrado del cultivo de fríjol y hacer transferencia de tecnología y capacitación en este tema, se desarrolló un proyecto en los municipios de El Carmen de Viboral, El Peñón, Marinilla y San Vicente, entre 1999 y 2000. Se conformaron ocho grupos de agricultores en ocho veredas, donde se establecieron el mismo número de parcelas demostrativas par el manejo integrado del cultivo, utilizando variedades mejoradas resistentes a la antracnosis. Se ejecutaron numerosos eventos de transferencia de tecnología y capacitación sobre manejo integrado de fríjol en cada vereda. Se recogió y analizó la información agronómica y económica de cada una de las parcelas y se aplico una encuesta de evaluación de los resultados finales del proyecto.Fríjol-Phaseolus vulgari
Thermodynamic properties of binary HCP solution phases from special quasirandom structures
Three different special quasirandom structures (SQS) of the substitutional
hcp binary random solutions (, 0.5, and 0.75) are
presented. These structures are able to mimic the most important pair and
multi-site correlation functions corresponding to perfectly random hcp
solutions at those compositions. Due to the relatively small size of the
generated structures, they can be used to calculate the properties of random
hcp alloys via first-principles methods. The structures are relaxed in order to
find their lowest energy configurations at each composition. In some cases, it
was found that full relaxation resulted in complete loss of their parental
symmetry as hcp so geometry optimizations in which no local relaxations are
allowed were also performed. In general, the first-principles results for the
seven binary systems (Cd-Mg, Mg-Zr, Al-Mg, Mo-Ru, Hf-Ti, Hf-Zr, and Ti-Zr) show
good agreement with both formation enthalpy and lattice parameters measurements
from experiments. It is concluded that the SQS's presented in this work can be
widely used to study the behavior of random hcp solutions.Comment: 15 pages, 8 figure
Determinación experimental del coeficiente de fricción empleando sensores movimiento
El objetivo de este artículo es mostrar una alternativa en la medición del coeficiente de fricción estático y dinámico entre dos superficies sólidas cuando se emplea el método del plano inclinado. La medición es realizada por medio de sensores de movimiento, aplicando los circuitos de acondicionamiento de señal los cuales son necesarios en su implementación. Los resultados muestran que los instrumentos empleados pueden ser adecuados en el cálculo de estos coeficientes
a-1 Adrenergic receptor antagonist doxazosin reverses hepatic stellate cells activation via induction of senescence
BACKGROUND: Activated hepatic stellate cells (aHSCs) are the main effector cells during liver fibrogenesis. α-1 adrenergic antagonist doxazosin (DX) was shown to be anti-fibrotic in an in vivo model of liver fibrosis (LF), but the mechanism remains to be elucidated. Recent studies suggest that reversion of LF can be achieved by inducing cellular senescence characterized by irreversible cell-cycle arrest and acquisition of the senescence-associated secretory phenotype (SASP). AIM: To elucidate the mechanism of the anti-fibrotic effect of DX and determine whether it induces senescence. METHODS: Primary culture-activated rat HSCs were used. mRNA and protein expression were measured by qPCR and Western blot, respectively. Cell proliferation was assessed by BrdU incorporation and xCelligence analysis. TGF-β was used for maximal HSC activation. Norepinephrine (NE), PMA and m-3M3FBS were used to activate alpha-1 adrenergic signaling. RESULTS: Expression of Col1α1 was significantly decreased by DX (10 µmol/L) at mRNA (-30 %) and protein level (-50 %) in TGF-β treated aHSCs. DX significantly reduced aHSCs proliferation and increased expression of senescence and SASP markers. PMA and m-3M3FBS reversed the effect of DX on senescence markers. CONCLUSION: Doxazosin reverses the fibrogenic phenotype of aHSCs and induces the senescence phenotype
Diet restriction in migraine, based on IgG against foods: A clinical double-blind, randomised, cross-over trial
Introduction: It is well-known that specific foods trigger
migraine attacks in some patients. We aimed to investigate the effect of diet
restriction, based on IgG antibodies against food antigens on the course of
migraine attacks in this randomised, double blind, cross-over, headache-diary
based trial on 30 patients diagnosed with migraine without aura
NeuroSpeech
NeuroSpeech is a software for modeling pathological speech signals considering different speech dimensions: phonation, articulation, prosody, and intelligibility. Although it was developed to model dysarthric speech signals from Parkinson's patients, its structure allows other computer scientists or developers to include other pathologies and/or measures. Different tasks can be performed: (1) modeling of the signals considering the aforementioned speech dimensions, (2) automatic discrimination of Parkinson's vs. non-Parkinson's, and (3) prediction of the neurological state according to the Unified Parkinson's Disease Rating Scale (UPDRS) score. The prediction of the dysarthria level according to the Frenchay Dysarthria Assessment scale is also provided
Characterisation of voice quality of Parkinson’s disease using differential phonological posterior features
Change in voice quality (VQ) is one of the first precursors of Parkinson’s disease (PD). Specifically, impacted phonation and articulation causes the patient to have a breathy, husky-semiwhisper and hoarse voice. A goal of this paper is to characterise a VQ spectrum – the composition of non-modal phonations – of voice in PD. The paper relates non-modal healthy phonations: breathy, creaky, tense, falsetto and harsh, with disordered phonation in PD. First, statistics are learned to differentiate the modal and non-modal phonations. Statistics are computed using phonological posteriors, the probabilities of phonological features inferred from the speech signal using a deep learning approach. Second, statistics of disordered speech are learned from PD speech data comprising 50 patients and 50 healthy controls. Third, Euclidean distance is used to calculate similarity of non-modal and disordered statistics, and the inverse of the distances is used to obtain the composition of non-modal phonation in PD. Thus, pathological voice quality is characterised using healthy non-modal voice quality “base/eigenspace”. The obtained results are interpreted as the voice of an average patient with PD and can be characterised by the voice quality spectrum composed of 30% breathy voice, 23% creaky voice, 20% tense voice, 15% falsetto voice and 12% harsh voice. In addition, the proposed features were applied for prediction of the dysarthria level according to the Frenchay assessment score related to the larynx, and significant improvement is obtained for reading speech task. The proposed characterisation of VQ might also be applied to other kinds of pathological speech
Structural and transport properties of epitaxial NaxCoO2 thin films
We have studied structural and transport properties of epitaxial NaxCoO2 thin
films on (0001) sapphire substrate prepared by topotaxially converting an
epitaxial Co3O4 film to NaxCoO2 with annealing in Na vapor. The films are c
axis oriented and in-plane aligned with [10 1 0] NaxCoO2 rotated by 30 degrees
from [10 1 0] sapphire. Different Na vapor pressures during the annealing
resulted in films with different Na concentrations, which showed distinct
transport properties
- …