Coxsackie B2 Virus Infection Causing Multiorgan Failure and Cardiogenic Shock in a 42-Year-Old Man

Infections from coxsackie B2 viruses often cause viral myocarditis and, only rarely, multisystem organ impairment. We present the unusual case of a 42-year-old man in whom coxsackie B2 virus infection caused multiorgan infection, necessitating distal pancreatectomy, splenectomy, renal dialysis, and venoarterial extracorporeal membrane oxygenation with mechanical ventilation. In addition, the patient had a rapid-eye-movement sleep-related conduction abnormality that caused frequent sinus pauses of longer than 10 s, presumably due to myocarditis from the coxsackievirus infection. He recovered after permanent pacemaker placement and was discharged from the hospital. We discuss our aggressive supportive care and the few other reports of multiorgan impairment from coxsackieviruses

InVitro-Q: A High-throughput Biosensor Used to Evaluate the Mechanism of Phagocytosis of Macrophages Using Different Particles

The method of phagocytosis of a particle can provide information on how macrophages respond to a detected particle. The response elicited varies based on the nature of the particle and in turn changes which receptor-mediated phagocytosis is initiated. We have developed a multi-well cell-based sensor that can monitor real-time biological changes in living cells, such as mass redistribution, and viscoelasticity. This system provides unique kinetic information regarding the phenotypic change in the cells post treatment. As a proof of principle study, we evaluate macrophage phagocytosis using three different particles: latex beads, Zymosan A, and Staphylococcus aureus. These studies show the InVitro-Q’s ability to distinguish and differentiate the unique physiological method of macrophage phagocytosis of an indigestible particle (latex beads), and digestible particles of different origins (Zymosan A (yeast cell wall) and S. aureus (wood bacteria). The real-time data generated illustrates the unique phenotypic signatures of macrophages in response to particle specific phagocytosis. The traces then dictate time points at which visualization will occur, and guides the elucidation of the mechanism of action

DFIG fault ride through improvement during VSC faults

The sensitivity of the doubly fed induction generator (DFIG) to external faults has motivated researchers to investigate the impact of various grid disturbances such as voltage sag and short circuit faults on the fault ride through (FRT) capability of the DFIG. However, no attention has been given to the impact of internal faults within voltage source converters (VSCs) that interface the DFIG with the grid, on the dynamic performance of the machine. This paper investigates the impact of various VSC faults on the dynamic performance and the FRT capability of the DFIG. Faults such as fire-through and flashover within the VSC switches are considered in this paper. Moreover, faults across the DC-link capacitor are included in this study as a common problem in the VSCs. The impact of these faults when they occur within the grid side converter (GSC) and rotor side converter (RSC) are investigated. A proper STATCOM controller to mitigate the effects of these faults on the FRT is proposed. The DFIG compliance with numerous and recently released FRT grid codes under these faults with and without the STATCOM are examined and compared. Furthermore, the capability of a proposed controller to bring the voltage profile at the point of common coupling (PCC) to the nominal steady-state level under five possible VSC faults cases is examined. The proposed controller is efficient, simple, and easy to implement

Estimation of general and specific combining abilities from a diallel cross of three inbred lines of Fayoumi chicks

International audienc

Heterosis in Fayoumi strain incrossing

International audienc

Effects of Light Scalar Mesons in η\to 3π Decay

We study the role of a possible nonet of light scalar mesons in the still interesting \eta \to 3\pi decay process, with the primary motivation of learning more about the scalars themselves. The framework is a conventional non-linear chiral Lagrangian of pseudoscalars and vectors, extended to include the scalars. The parameters involving the scalars were previously obtained to fit the s-wave \pi\pi and \piK scatterings in the region up to about 1 GeV as well as the strong decay \eta\u27 \to \eta \pi\pi. At first, one might expect a large enhancement from diagrams including a light \sigma(560). However there is an amusing cancellation mechanism which prevents this from occurring. In the simplest model there is an enhancement of about 13 per cent in the \e3p decay rate due to the scalars. In a more complicated model which includes derivative type symmetry breakers, the cancellation is modified and the scalars contribute about 30 percent of the total decay rate (although the total is not significantly changed). The vectors do not contribute much. Our model produces a reasonable estimate for the related a_0(980)-f_0(980) mixing strength, which has been a topic of current debate. Promising directions for future work along the present line are suggested

Modèle de régression optimale des traits de conformation et de la production laitière des troupeaux bovins de race kouri élevés à la station de Sayam du Niger.

Objectif : évaluer en station, la pertinence des traits de conformation traditionnellement privilégiés par les éleveurs kouri, pour l’identification des meilleures vaches laitières.Méthodologie et résultats : La production laitière et treize traits biométriques ont été évalués sur 54 vaches, de septembre 2015 à février 2016, au Centre de Multiplication de Bétail de Sayam, après six (6) mois de contrôle laitier. Il est constaté que la production laitière journalière était positivement corrélée aux traits de conformation du bassin (largeur aux ischions (r = 0.35**) et la largeur aux trochanters (r = 0.36**)), à la profondeur de poitrine (r = 0.27*), à la largeur aux poitrines (r = 0.29*) et au rapport de la largeur aux poitrines sur la largeur aux hanches (r = 0.28*). Le modèle de régression optimale de la production laitière qui s’est bien ajusté de façon hautement significative (p = 0.004) est un modèle utilisant la largeur-Trochanters et le rapport largeur- Poitrine/Largeur-hanche comme indices prévisionnels. La valeur du R carrée ajusté du modèle et de l’erreur standard des résidus étaient respectivement 0.16 et 0.43.Conclusion et perspectives : les traits biométriques intéressants, identifiés comme promoteurs dans cette étude, peuvent être inclus dans le développement de mécanismes de sélection qui peut encore être couplé à des techniques modernes de sélection. Le modèle ainsi obtenu, pourrait être utilisé pour prédire la production de lait des vaches kouri ou à des fins de sélection.Mots clés : Corrélation, modélisation, traits de conformation, production laitière, kour