Synthesis, characterisation and biological activity of gold(III) catecholate and related complexes

The reactions of the cyclometallated gold(III) complexes [LAuCl₂] [L=2-(dimethylaminomethyl)phenyl, 2-benzylpyridyl or 2-anilinopyridyl] with catechol, tetrachlorocatechol, or the cyclic α,β-diketone SCH(CO2Et)C(O)C(O)CH(CO2Et) give stable complexes containing five-membered Au-O-C-C-O rings. These represent the first examples of well-characterised gold(III) catecholate complexes. Similarly, reactions with 2-acetamidophenol [HOC₆H₄NHC(O)CH₃] give complexes with the related Au---N---C---C---O ring. The complexes were characterised by NMR spectroscopy, electrospray ionisation mass spectrometry, elemental microanalysis, and in the case of the complex [(2-benzylpyridyl)Au{OC₆H₄NC(O)CH₃}] by an X-ray crystal structure determination. Several complexes show high activity towards P388 murine leukemia cells

Survival of microorganisms in desert soil exposed to five years of continuous very high vacuum

Microorganism survivability in desert algal soil crust under continuous very high vacuu

Migration of Ca II H bright points in the internetwork

The migration of magnetic bright point-like features (MBP) in the lower solar atmosphere reflects the dispersal of magnetic flux as well as the horizontal flows of the atmospheric layer they are embedded in. We analyse trajectories of the proper motion of intrinsically magnetic, isolated internetwork Ca II H MBPs (mean lifetime 461 +- 9 s) to obtain their diffusivity behaviour. We use seeing-free high spatial and temporal resolution image sequences of quiet-Sun, disc-centre observations obtained in the Ca II H 3968 {\AA} passband of the Sunrise Filter Imager (SuFI) onboard the Sunrise balloon-borne solar observatory. Small MBPs in the internetwork are automatically tracked. The trajectory of each MBP is then calculated and described by a diffusion index ({\gamma}) and a diffusion coefficient (D). We further explore the distribution of the diffusion indices with the help of a Monte Carlo simulation. We find {\gamma} = 1.69 +- 0.08 and D = 257 +- 32 km^2/s averaged over all MBPs. Trajectories of most MBPs are classified as super-diffusive, i.e., {\gamma} > 1, with the determined {\gamma} being to our knowledge the largest obtained so far. A direct correlation between D and time-scale ({\tau}) determined from trajectories of all MBPs is also obtained. We discuss a simple scenario to explain the diffusivity of the observed, relatively short-lived MBPs while they migrate within a small area in a supergranule (i.e., an internetwork area). We show that the scatter in the {\gamma} values obtained for individual MBPs is due to their limited lifetimes. The super-diffusive MBPs can be well-described as random walkers (due to granular evolution and intergranular turbu- lence) superposed on a large systematic (background) velocity, caused by granular, mesogranular and supergranular flows.Comment: 10 pages, 7 figures, 3 table

Emissions Trading with Profit-Neutral Permit Allocations

This paper examines the operation of an emissions trading scheme (ETS) in a Cournot oligopoly. We study the impact of the ETS on industry output, price, costs, emissions, and profits. In particular, we develop formulae for the number of emissions permits that have to be freely allocated to firms in order to neutralize any adverse impact the ETS may have on profits. These formulae tell us that the profit impact of the ETS is usually limited. Indeed, under quite general conditions, industry profits are preserved so long as firms are freely allocated a fraction of their total demand for permits, with this fraction being lower than the industry's Herfindahl index.Emissions trading, permit allocation, profit-neutrality, cost pass-through, abatement, grandfathering

WASP-1: A lithium- and metal-rich star with an oversized planet

In this paper we present our results of a comprehensive spectroscopicanalysis of WASP-1, the host star to the exoplanet WASP-1b. We derive T_eff = 6110 +/- 45 K, log g = 4.28 +/- 0.15, and [M/H] = 0.23 +/- 0.08, and also a high abundance of lithium, log n(Li) = 2.91 +/- 0.05. These parameters suggests an age for the system of 1-3 Gyr and a stellar mass of 1.25-1.35 M_sun. This means that WASP-1 has properties very similar to those of HD 149026, the host star for the highest density planet yet detected. Moreover, their planets orbit at comparable distances and receive comparable irradiating fluxes from their host stars. However, despite the similarity of WASP-1 with HD 149026, their planets have strongly different densities. This suggests that gas-giant planet density is not a simple function of host-star metallicity or of radiation environment at ages of ~2 Gyr.Comment: Accepted for publication in MNRAS. 6 pages, 4 figure

Thanks, but no thanks: women's avoidance of help-seeking in the context of a dependency-related stereotype

The stereotype that women are dependent on men is a commonly verbalized, potentially damaging aspect of benevolent sexism. We investigated how women may use behavioral disconfirmation of the personal applicability of the stereotype to negotiate such sexism. In an experiment (N = 86), we manipulated female college students’ awareness that women may be stereotyped by men as dependent. We then placed participants in a situation where they needed help. Women made aware of the dependency stereotype (compared to controls who were not) were less willing to seek help. They also displayed a stronger negative correlation between help-seeking and post help-seeking affect - such that the more help they sought, the worse they felt. We discuss the relevance of these findings for research concerning women’s help-seeking and their management of sexist stereotyping in everyday interaction. We also consider the implications of our results for those working in domains such as healthcare, teaching and counseling, where interaction with individuals in need and requiring help is common

The Success Story of Gold-Based Catalysts for Gas- and Liquid-Phase Reactions: A Brief Perspective and Beyond

Gold has long held the fascination of mankind. For millennia it has found use in art, cosmetic metallurgy and architecture; this element is seen as the ultimate statement of prosperity and beauty. This myriad of uses is made possible by the characteristic inertness of bulk gold; allowing it to appear long lasting and above the tarnishing experienced by other metals, in part providing its status as the most noble meta

Gate recess engineering of pseudomorphic In0.30GaAs/GaAs HEMTs

The authors report how the performance of 0.12 μm GaAs pHEMTs is improved by controlling both the gate recess width, using selective dry etching, and the gate position in the source drain gap, using electron beam lithography. pHEMTs with a transconductance of 600 mS/mm, off state breakdown voltages >2 V, fτ of 120 GHz, f max of 180 GHz and MAG of 13.5 dB at 60 GHz are reported

A large-scale analysis of mRNAs expressed by primary mesenchyme cells of the sea urchin embryo

The primary mesenchyme cells (PMCs) of the sea urchin embryo have been an important model system for the analysis of cell behavior during gastrulation. To gain an improved understanding of the molecular basis of PMC behavior, a set of 8293 expressed sequenced tags (ESTs) was derived from an enriched population of mid-gastrula stage PMCs. These ESTs represented approximately 1200 distinct proteins, or about 15% of the mRNAs expressed by the gastrula stage embryo. 655 proteins were similar (P<10-7 by BLAST comparisons) to other proteins in GenBank, for which some information is available concerning expression and/or function. Another 116 were similar to ESTs identified in other organisms, but not further characterized. We conservatively estimate that sequences encoding at least 435 additional proteins were included in the pool of ESTs that did not yield matches by BLAST analysis. The collection of newly identified proteins includes many candidate regulators of primary mesenchyme morphogenesis, including PMC-specific extracellular matrix proteins, cell surface proteins, spicule matrix proteins and transcription factors. This work provides a basis for linking specific molecular changes to specific cell behaviors during gastrulation. Our analysis has also led to the cloning of several key components of signaling pathways that play crucial roles in early sea urchin development