918 research outputs found

    A Data Quality Framework for Process Mining of Electronic Health Record Data

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    Reliable research demands data of known quality. This can be very challenging for electronic health record (EHR) based research where data quality issues can be complex and often unknown. Emerging technologies such as process mining can reveal insights into how to improve care pathways but only if technological advances are matched by strategies and methods to improve data quality. The aim of this work was to develop a care pathway data quality framework (CP-DQF) to identify, manage and mitigate EHR data quality in the context of process mining, using dental EHRs as an example. Objectives: To: 1) Design a framework implementable within our e-health record research environments; 2) Scale it to further dimensions and sources; 3) Run code to mark the data; 4) Mitigate issues and provide an audit trail. Methods: We reviewed the existing literature covering data quality frameworks for process mining and for data mining of EHRs and constructed a unified data quality framework that met the requirements of both. We applied the framework to a practical case study mining primary care dental pathways from an EHR covering 41 dental clinics and 231,760 patients in the Republic of Ireland. Results: Applying the framework helped identify many potential data quality issues and mark-up every data point affected. This enabled systematic assessment of the data quality issues relevant to mining care pathways. Conclusion: The complexity of data quality in an EHR-data research environment was addressed through a re-usable and comprehensible framework that met the needs of our case study. This structured approach saved time and brought rigor to the management and mitigation of data quality issues. The resulting metadata is being used within cohort selection, experiment and process mining software so that our research with this data is based on data of known quality. Our framework is a useful starting point for process mining researchers to address EHR data quality concerns

    Contrast-induced nephropathy.

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    Radiological procedures utilizing intravascular iodinated contrast media are being widely applied for both diagnostic and therapeutic purposes and represent one of the main causes of contrast-induced nephropathy (CIN) and hospital-acquired renal failure. Due to the lack of any effective treatment, prevention of this iatrogenic disease, which is associated with significant in-hospital and long-term morbidity and mortality and increased costs, is the key strategy. However, prevention of CIN continues to elude clinicians and is a major concern during percutaneous coronary interventions (PCI), as patients undergoing these procedures often have multiple comorbidities. The purpose of this article is to examine the pathophysiology, risk factors, and clinical course of CIN, as well as the most recent studies dealing with its prevention and potential therapeutic interventions, especially during PCI

    Toothbrushing rules: power dynamics and toothbrushing in children

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    Dental caries is a disease of childhood social disa dvantage being considered as a marker of family dep rivation and relative poverty. School-based programmes such as, ‘Winning Smiles’ (WS) have been used to promote toothbrushing with luoride toothpaste in children r esiding in areas of high social deprivation. Withou t a clear understanding of the underlying toothbrushing dynam ic how could WS achieve its deined aim to promote toothbrushing as a self-care practice in children r esiding in areas of greatest deprivation? The need to research the dynamics of childhood toothbrushing remained. T he aim of this qualitative exploration was twofold, irst to explore children’s views of toothbrushing and se condly, to relect, if possible, on the degree to wh ich the children’s views and experiences can aid an underst anding of the power dynamics of toothbrushing pract ices in childhood. In order to achieve these aims it was necessary to use a child-centred approach to glean the thoughts, values and opinions of the participating children. The children who participated were aged b e- tween 8-9-years-old and resided and attended school s in the most deprived parts of Dublin and Belfast. The data analysis was theoretically underpinned by the work of Foucault and Nettleton. The children had a series of toothbrushing rules which were a conglomerate of ‘do’s’ and ‘don’ts’. The rules relected an element of con - lict in the children’s behaviour since they describ ed what the children felt they ‘should’ do (‘toothb rushing rules’), as well as what they ‘actually’ did (‘toot hbrushing practices’). The toothbrushing rules were mainly based on their parental household rules which the c hildren incorporated into their toothbrushing pract ices. It is suggested that children incorporate informati on from parents, school-based programmes and the de ntist into their toothbrushing practices. This qualitativ e exploration has allowed the process of understand ing the power dynamics associated with children’s toothbrushing t o begin. In order to gain a greater understanding from the child’s perspective greater time is need t o appreciate how children incorporate what appears to be a rather mundane aspect of everyday life into their health repertoire

    Fluoride and oral health

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    The discovery during the first half of the 20th century of the link between natural fluoride, adjusted fluoride levels in drinking water and reduced dental caries prevalence proved to be a stimulus for worldwide on-going research into the role of fluoride in improving oral health. Epidemiological studies of fluoridation programmes have confirmed their safety and their effectiveness in controlling dental caries. Major advances in our knowledge of how fluoride impacts the caries process have led to the development, assessment of effectiveness and promotion of other fluoride vehicles including salt, milk, tablets, toothpaste, gels and varnishes. In 1993, the World Health Organization convened an Expert Committee to provide authoritative information on the role of fluorides in the promotion of oral health throughout the world (WHO TRS 846, 1994). This present publication is a revision of the original 1994 document, again using the expertise of researchers from the extensive fields of knowledge required to successfully implement complex interventions such as the use of fluorides to improve dental and oral health. Financial support for research into the development of these new fluoride strategies has come from many sources including government health departments as well as international and national grant agencies. In addition, the unique role which industry has played in the development, formulation, assessment of effectiveness and promotion of the various fluoride vehicles and strategies is noteworthy. This updated version of ‘Fluoride and Oral Health’ has adopted an evidence-based approach to its commentary on the different fluoride vehicles and strategies and also to its recommendations. In this regard, full account is taken of the many recent systematic reviews published in peer reviewed literature

    The dietary impact of the Norman Conquest: A multiproxy archaeological investigation of Oxford, UK

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    Archaeology has yet to capitalise on the opportunities offered by bioarchaeological approaches to examine the impact of the 11th-century AD Norman Conquest of England. This study utilises an integrated multiproxy analytical approach to identify and explain changes and continuities in diet and foodways between the 10th and 13th centuries in the city of Oxford, UK. The integration of organic residue analysis of ceramics, carbon (δ13C) and nitrogen (δ15N) isotope analysis of human and animal bones, incremental analysis of δ13C and δ15N from human tooth dentine and palaeopathological analysis of human skeletal remains has revealed a broad pattern of increasing intensification and marketisation across various areas of economic practice, with a much lesser and more short-term impact of the Conquest on everyday lifestyles than is suggested by documentary sources. Nonetheless, isotope data indicate short-term periods of instability, particularly food insecurity, did impact individuals. Evidence of preferences for certain foodstuffs and cooking techniques documented among the elite classes were also observed among lower-status townspeople, suggesting that Anglo-Norman fashions could be adopted across the social spectrum. This study demonstrates the potential for future archaeological research to generate more nuanced understanding of the cultural impact of the Norman Conquest of England, while showcasing a method which can be used to elucidate the undocumented, everyday implications of other large-scale political events on non-elites

    School based health-education programmes, health-learning capacity and child oral health-related quality of life

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    Objective: To use a model of health learning to examine the role of health-learning capacity and the effect of a school-based oral health education intervention (Winning Smiles) on the health outcome, child oral health–related quality of life (COHRQoL). Setting: Primary schools, high social deprivation, Ireland/Northern Ireland. Design: Cluster randomised controlled trial. Method: A total of 383, 7- to 8-year-old children were invited to participate and randomly allocated into intervention and control conditions. Baseline and 12-month follow-up assessments of COHRQoL, self-esteem, toothbrushing–fluoride toothpaste knowledge and unstimulated saliva samples were made. An 18-hour post-brushing, saliva fluoride concentration was used to assess toothbrushing with fluoride toothpaste (behaviour). The data were entered onto SPSSv22. Structural equation modelling was applied using AMOSv22 to test for the role of health-learning capacity (baseline self-esteem and COHRQoL) and simultaneous effects of Winning Smiles upon knowledge, behaviour and COHRQoL (at follow-up). Results: A total of 238 children participated at baseline and follow-up. A partial latent hybrid model fitted the data reasonably well (χ2 = 65.6, df = 50, p = .07) as shown in addition by a Comparative Fit Index of .97 and a Root Mean Square Error of Approximation (RMSEA) value of .042 (90% confidence interval [CI]: .00, .06). The intervention had a significant effect on toothbrushing–fluoride toothpaste knowledge (p < .03) and an effect on COHRQoL at the 6% level (p < .06). Knowledge was strongly associated with saliva fluoride concentration (p < .002). Conclusion: The model of health-learning capacity assisted in explaining the effect of a school-based intervention upon knowledge, toothbrushing behaviour and tentatively on COHRQoL

    Prevalence of overweight and obesity on the island of Ireland: results from the North South Survey of Children's Height, Weight and Body Mass Index, 2002

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    <p>Abstract</p> <p>Background</p> <p>Childhood obesity is emerging as a major public health problem in developed and developing countries worldwide. The aim of this survey was to establish baseline data on the prevalence and correlates of overweight and obesity among children and adolescents in the Republic of Ireland (RoI) and Northern Ireland (NI).</p> <p>Methods</p> <p>The heights and weights of 19,617 school-going children and adolescents aged between 4 and 16 years in NI and RoI were measured using standardised and calibrated scales and measures. The participants were a representative cross-sectional sample of children randomly selected on the basis of age, gender and geographical location of the school attended. Overweight and obesity were classified according to standard IOTF criteria.</p> <p>Results</p> <p>Males were taller than females, children in RoI were taller than those in NI and the more affluent were taller than the less well off. The overall prevalence of overweight and obesity was higher among females than males in both jurisdictions. Overall, almost one in four boys (23% RoI and NI) and over one in four girls (28% RoI, 25% NI) were either overweight or obese. In RoI, the highest prevalence of overweight was among 13 year old girls (32%) and obesity among 7 year old girls (11%). In NI the highest prevalence of overweight and obesity were found among 11 and 8 year old girls respectively (33% and 13%).</p> <p>Conclusion</p> <p>These figures confirm the emergence of the obesity epidemic among children in Ireland, a wealthy country with the European Union. The results serve to underpin the urgency of implementing broad intersectoral measures to reduce calorie intake and increase levels of physical activity, particularly among children.</p

    Barriers and facilitators for prevention in Danish dental care

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    Objective: To explore barriers and facilitators to oral disease prevention in Danish dental care from a multi-stakeholder perspective. Methods: Eleven semi-structured focus groups and interviews about Danish oral healthcare were conducted with 27 stakeholders (general public, dental teams, dental policy makers) in Copenhagen. Transcripts were analyzed using deductive thematic analysis independently by KR and HL, supervised by JC and KVC. Results: Seven broad themes were identified, including both barriers and facilitators: Knowledge and attitudes, Education and training, Regulation, Incentivization, Multidisciplinary approach, Access to care and the Dental professional-patient relationship. Whilst all themes were relevant to each group of stakeholders, the salient driver within each theme was different for each group. Conclusions: Stakeholder perspectives on the Danish Oral health care system suggest the following are important features for a preventively focused system: (a) Involving all stakeholders in oral healthcare planning. (b) Securing sufficient and ongoing briefing regarding disease prevention for all stakeholders. (c) Regulatory support and creation of incentives to promote and facilitate implementation of disease prevention. (d) Appropriate prevention for disadvantaged groups within society which may be possible to a higher degree by means of multidisciplinary collaboration. (e) Personal relations between the patient and the professional based on mutual trust
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