550 research outputs found
The Paradoxical Forces for the Classical Electromagnetic Lag Associated with the Aharonov-Bohm Phase Shift
The classical electromagnetic lag assocated with the Aharonov-Bohm phase
shift is obtained by using a Darwin-Lagrangian analysis similar to that given
by Coleman and Van Vleck to identify the puzzling forces of the Shockley-James
paradox. The classical forces cause changes in particle velocities and so
produce a relative lag leading to the same phase shift as predicted by Aharonov
and Bohm and observed in experiments. An experiment is proposed to test for
this lag aspect implied by the classical analysis but not present in the
currently-accepted quantum topological description of the phase shift.Comment: 8 pages, 3 figure
Effects of antenatal betamethasone on preterm human and mouse ductus arteriosus: comparison with baboon data.
BackgroundAlthough studies involving preterm infants â€34 weeks gestation report a decreased incidence of patent ductus arteriosus after antenatal betamethasone, studies involving younger gestation infants report conflicting results.MethodsWe used preterm baboons, mice, and humans (â€276/7 weeks gestation) to examine betamethasone's effects on ductus gene expression and constriction both in vitro and in vivo.ResultsIn mice, betamethasone increased the sensitivity of the premature ductus to the contractile effects of oxygen without altering the effects of other contractile or vasodilatory stimuli. Betamethasone's effects on oxygen sensitivity could be eliminated by inhibiting endogenous prostaglandin/nitric oxide signaling. In mice and baboons, betamethasone increased the expression of several developmentally regulated genes that mediate oxygen-induced constriction (K+ channels) and inhibit vasodilator signaling (phosphodiesterases). In human infants, betamethasone increased the rate of ductus constriction at all gestational ages. However, in infants born â€256/7 weeks gestation, betamethasone's contractile effects were only apparent when prostaglandin signaling was inhibited, whereas at 26-27 weeks gestation, betamethasone's contractile effects were apparent even in the absence of prostaglandin inhibitors.ConclusionsWe speculate that betamethasone's contractile effects may be mediated through genes that are developmentally regulated. This could explain why betamethasone's effects vary according to the infant's developmental age at birth
Exploration and exploitation in the presence of network externalities
This paper examines the conditions under which exploration of a new, incompatible technologyis
conducive to firm growth in the presence of network externalities. In particular,
this studyis motivated bythe divergent evolutions of the PC and the workstation markets in
response to a new technology: reduced instruction set computing (RISC). In the PC market,
Intel has developed new microprocessors bymaintaining compatibilitywith the established
architecture, whereas it was radicallyr eplaced byRISC in the workstation market. History
indicates that unlike the PC market, the workstation market consisted of a large number
of power users, who are less sensitive to compatibilitythan ordinaryusers. Our numerical
analysis indicates that the exploration of a new, incompatible technologyis more likelyto
increase the chance of firm growth when there are a substantial number of power users or
when a new technologyis introduced before an established technologytakes off.
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Private Copying and Fair Compensation: An Empirical Study of Copyright Levies in Europe
Distorted maternal mental representations and atypical behavior in a clinical sample of violence-exposed mothers and their toddlers
Objective: To determine whether maternal violence-related posttraumatic stress disorder (PTSD), reflective functioning (RF), and/or quality of mental representations of her child predicts maternal behavior within a referred sample of mothers exposed to interpersonal violence and their children (aged 8â50 months). Method: A total of 41 dyads completed 2 videotaped visits including measures of maternal mentalrepresentations and behavior. Results: Negative and distorted maternal mental representations predicted atypical behavior (Cohenâs d \u3e 1.0). Although maternal PTSD and RF impacted mental representations, no significant relationships were found between PTSD, RF, and overall atypical caregiving behavior. Severity of maternal PTSD was, however, positively correlated with the avoidant caregiving behaviorsubscale. Conclusions: Maternal mental representations of her child are useful risk indicators that mark dysregulation of trauma-associated emotions in the caregiver
Can filesharers be triggered by economic incentives? Results of an experiment
Illegal filesharing on the internet leads to considerable financial losses for artists and copyright owners as well as producers and sellers of music. Thus far, measures to contain this phenomenon have been rather restrictive. However, there are still a considerable number of illegal systems, and users are able to decide quite freely between legal and illegal downloads because the latter are still difficult to sanction. Recent economic approaches account for the improved bargaining position of users. They are based on the idea of revenue-splitting between professional sellers and peers. In order to test such an innovative business model, the study reported in this article carried out an experiment with 100 undergraduate students, forming five small peer-to-peer networks.The networks were confronted with different economic conditions.The results indicate that even experienced filesharers hold favourable attitudes towards revenue-splitting.They seem to be willing to adjust their behaviour to different economic conditions
Kinematics and hydrodynamics of spinning particles
In the first part (Sections 1 and 2) of this paper --starting from the Pauli
current, in the ordinary tensorial language-- we obtain the decomposition of
the non-relativistic field velocity into two orthogonal parts: (i) the
"classical part, that is, the 3-velocity w = p/m OF the center-of-mass (CM),
and (ii) the so-called "quantum" part, that is, the 3-velocity V of the motion
IN the CM frame (namely, the internal "spin motion" or zitterbewegung). By
inserting such a complete, composite expression of the velocity into the
kinetic energy term of the non-relativistic classical (i.e., newtonian)
lagrangian, we straightforwardly get the appearance of the so-called "quantum
potential" associated, as it is known, with the Madelung fluid. This result
carries further evidence that the quantum behaviour of micro-systems can be
adirect consequence of the fundamental existence of spin. In the second part
(Sections 3 and 4), we fix our attention on the total 3-velocity v = w + V, it
being now necessary to pass to relativistic (classical) physics; and we show
that the proper time entering the definition of the four-velocity v^mu for
spinning particles has to be the proper time tau of the CM frame. Inserting the
correct Lorentz factor into the definition of v^mu leads to completely new
kinematical properties for v_mu v^mu. The important constraint p_mu v^mu = m,
identically true for scalar particles, but just assumed a priori in all
previous spinning particle theories, is herein derived in a self-consistent
way.Comment: LaTeX file; needs kapproc.st
Health Diplomacy the Adaptation of Global Health Interventions to Local Needs in sub-Saharan Africa and Thailand: Evaluating Findings from Project Accept (HPTN 043).
Study-based global health interventions, especially those that are conducted on an international or multi-site basis, frequently require site-specific adaptations in order to (1) respond to socio-cultural differences in risk determinants, (2) to make interventions more relevant to target population needs, and (3) in recognition of 'global health diplomacy' issues. We report on the adaptations development, approval and implementation process from the Project Accept voluntary counseling and testing, community mobilization and post-test support services intervention. We reviewed all relevant documentation collected during the study intervention period (e.g. monthly progress reports; bi-annual steering committee presentations) and conducted a series of semi-structured interviews with project directors and between 12 and 23 field staff at each study site in South Africa, Zimbabwe, Thailand and Tanzania during 2009. Respondents were asked to describe (1) the adaptations development and approval process and (2) the most successful site-specific adaptations from the perspective of facilitating intervention implementation. Across sites, proposed adaptations were identified by field staff and submitted to project directors for review on a formally planned basis. The cross-site intervention sub-committee then ensured fidelity to the study protocol before approval. Successfully-implemented adaptations included: intervention delivery adaptations (e.g. development of tailored counseling messages for immigrant labour groups in South Africa) political, environmental and infrastructural adaptations (e.g. use of local community centers as VCT venues in Zimbabwe); religious adaptations (e.g. dividing clients by gender in Muslim areas of Tanzania); economic adaptations (e.g. co-provision of income generating skills classes in Zimbabwe); epidemiological adaptations (e.g. provision of 'youth-friendly' services in South Africa, Zimbabwe and Tanzania), and social adaptations (e.g. modification of terminology to local dialects in Thailand: and adjustment of service delivery schedules to suit seasonal and daily work schedules across sites). Adaptation selection, development and approval during multi-site global health research studies should be a planned process that maintains fidelity to the study protocol. The successful implementation of appropriate site-specific adaptations may have important implications for intervention implementation, from both a service uptake and a global health diplomacy perspective
Un élément fini de poutre fissurée application à la dynamique des arbres tournants
International audienceDans ce travail on présente une méthode originale de construction d'un élément fini de poutre affectée de fissurations. La souplesse additionnelle due à la présence des fissures est identifiée à partir de calculs éléments finis tridimensionnels tenant compte des conditions de contact unilatéral entre les lÚvres. Cette souplesse est répartie sur toute la longueur de l'élément dont on se propose de construire la matrice de rigidité. La démarche permet un gain considérable en temps de calcul par rapport à la représentation nodale de la section fissurée lors de l'intégration temporelle de systÚmes différentiels en dynamique des structures
Espiral do conhecimento em frameworks de gestão do conhecimento: o caso de duas organizaçÔes em Portugal
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