110 research outputs found
Accurate proteome-wide protein quantification from high-resolution 15N mass spectra
In quantitative mass spectrometry-based proteomics, the metabolic incorporation of a single source of 15N-labeled nitrogen has many advantages over using stable isotope-labeled amino acids. However, the lack of a robust computational framework for analyzing the resulting spectra has impeded wide use of this approach. We have addressed this challenge by introducing a new computational methodology for analyzing 15N spectra in which quantification is integrated with identification. Application of this method to an Escherichia coli growth transition reveals significant improvement in quantification accuracy over previous methods
International Instrument on Permitted Uses in Copyright Law
Funder: Max Planck Institute for Innovation and Competition (IMPRS-CI, IP MPG) (2
Access to knowledge under the international copyright regime, the WIPO development agenda and the European Communities' new external trade and IP policy
The International Law Relation between TRIPs and Subsequent TRIPs-Plus Free Trade Agreements: Towards Safeguarding TRIPs Flexibilities
Protecting Intellectual Property through Trade and Investment Agreements: Concepts, Norm-setting, and Dispute Settlement
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