3,690 research outputs found
Osmotic force resisting chain insertion in a colloidal suspension
We consider the problem of inserting a stiff chain into a colloidal
suspension of particles that interact with it through excluded volume forces.
The free energy of insertion is associated with the work of creating a cavity
devoid of colloid and sufficiently large to accomodate the chain. The
corresponding work per unit length is the force that resists the entry of the
chain into the colloidal suspension. In the case of a hard sphere fluid, this
work can be calculated straightforwardly within the scaled particle theory; for
solutions of flexible polymers, on the other hand, we employ simple scaling
arguments. The forces computed in these ways are shown, for nanometer chain and
colloid diameters, to be of the order of tens of pN for solution volume
fraction for biophysical processes such as the ejection of DNA from viral
capsids into the cell cytoplasm.Comment: 16 pages,3 figures. Accepted for publication in European Physical
Journal
Development and application of a local linearization algorithm for the integration of quaternion rate equations in real-time flight simulation problems
High angular rates encountered in real-time flight simulation problems may require a more stable and accurate integration method than the classical methods normally used. A study was made to develop a general local linearization procedure of integrating dynamic system equations when using a digital computer in real-time. The procedure is specifically applied to the integration of the quaternion rate equations. For this application, results are compared to a classical second-order method. The local linearization approach is shown to have desirable stability characteristics and gives significant improvement in accuracy over the classical second-order integration methods
Personality factors in flight operations. Volume 1: Leader characteristics and crew performance in a full-mission air transport simulation
Crew effectiveness is a joint product of the piloting skills, attitudes, and personality characteristics of team members. As obvious as this point might seem, both traditional approaches to optimizing crew performance and more recent training development highlighting crew coordination have emphasized only the skill and attitudinal dimensions. This volume is the first in a series of papers on this simulation. A subsequent volume will focus on patterns of communication within crews. The results of a full-mission simulation research study assessing the impact of individual personality on crew performance is reported. Using a selection algorithm described in previous research, captains were classified as fitting one of three profiles along a battery of personality assessment scales. The performances of 23 crews led by captains fitting each profile were contrasted over a one-and-one-half-day simulated trip. Crews led by captains fitting a positive Instrumental-Expressive profile (high achievement motivation and interpersonal skill) were consistently effective and made fewer errors. Crews led by captains fitting a Negative Expressive profile (below average achievement motivation, negative expressive style, such as complaining) were consistently less effective and made more errors. Crews led by captains fitting a Negative Instrumental profile (high levels of competitiveness, verbal aggressiveness, and impatience and irritability) were less effective on the first day but equal to the best on the second day. These results underscore the importance of stable personality variables as predictors of team coordination and performance
The BetaCage, an ultra-sensitive screener for surface contamination
Material screening for identifying low-energy electron emitters and
alpha-decaying isotopes is now a prerequisite for rare-event searches (e.g.,
dark-matter direct detection and neutrinoless double-beta decay) for which
surface radiocontamination has become an increasingly important background. The
BetaCage, a gaseous neon time-projection chamber, is a proposed ultra-sensitive
(and nondestructive) screener for alpha- and beta-emitting surface contaminants
to which existing screening facilities are insufficiently sensitive.
Sensitivity goals are 0.1 betas per keV-m-day and 0.1 alphas per m-day,
with the former limited by Compton scattering of photons in the screening
samples and (thanks to tracking) the latter expected to be signal-limited;
radioassays and simulations indicate backgrounds from detector materials and
radon daughters should be subdominant. We report on details of the background
simulations and detector design that provide the discrimination, shielding, and
radiopurity necessary to reach our sensitivity goals for a chamber with a
9595 cm sample area positioned below a 40 cm drift region and
monitored by crisscrossed anode and cathode planes consisting of 151 wires
each.Comment: 5 pages, 3 figures, Proceedings of Low Radioactivity Techniques (LRT)
2013, Gran Sasso, Italy, April 10-12, 201
Test of classical nucleation theory on deeply supercooled high-pressure simulated silica
We test classical nucleation theory (CNT) in the case of simulations of
deeply supercooled, high density liquid silica, as modelled by the BKS
potential. We find that at density ~g/cm, spontaneous nucleation
of crystalline stishovite occurs in conventional molecular dynamics simulations
at temperature T=3000 K, and we evaluate the nucleation rate J directly at this
T via "brute force" sampling of nucleation events. We then use parallel,
constrained Monte Carlo simulations to evaluate , the free energy
to form a crystalline embryo containing n silicon atoms, at T=3000, 3100, 3200
and 3300 K. We find that the prediction of CNT for the n-dependence of fits reasonably well to the data at all T studied, and at 3300 K yields a
chemical potential difference between liquid and stishovite that matches
independent calculation. We find that , the size of the critical nucleus,
is approximately 10 silicon atoms at T=3300 K. At 3000 K, decreases to
approximately 3, and at such small sizes methodological challenges arise in the
evaluation of when using standard techniques; indeed even the
thermodynamic stability of the supercooled liquid comes into question under
these conditions. We therefore present a modified approach that permits an
estimation of at 3000 K. Finally, we directly evaluate at T=3000
K the kinetic prefactors in the CNT expression for J, and find physically
reasonable values; e.g. the diffusion length that Si atoms must travel in order
to move from the liquid to the crystal embryo is approximately 0.2 nm. We are
thereby able to compare the results for J at 3000 K obtained both directly and
based on CNT, and find that they agree within an order of magnitude.Comment: corrected calculation, new figure, accepted in JC
Conditional strategies and the evolution of cooperation in spatial public goods games
The fact that individuals will most likely behave differently in different
situations begets the introduction of conditional strategies. Inspired by this,
we study the evolution of cooperation in the spatial public goods game, where
besides unconditional cooperators and defectors, also different types of
conditional cooperators compete for space. Conditional cooperators will
contribute to the public good only if other players within the group are likely
to cooperate as well, but will withhold their contribution otherwise. Depending
on the number of other cooperators that are required to elicit cooperation of a
conditional cooperator, the latter can be classified in as many types as there
are players within each group. We find that the most cautious cooperators, such
that require all other players within a group to be conditional cooperators,
are the undisputed victors of the evolutionary process, even at very low
synergy factors. We show that the remarkable promotion of cooperation is due
primarily to the spontaneous emergence of quarantining of defectors, which
become surrounded by conditional cooperators and are forced into isolated
convex "bubbles" from where they are unable to exploit the public good. This
phenomenon can be observed only in structured populations, thus adding to the
relevance of pattern formation for the successful evolution of cooperation.Comment: 7 two-column pages, 7 figures; accepted for publication in Physical
Review
Bivalirudin versus heparin in primary PCI: clinical outcomes and cost analysis.
Background: The evidence for benefits of bivalirudin over heparin has recently been challenged. We aimed to analyse the safety and cost-effectiveness following reintroduction of heparin instead of bivalirudin as the standard anticoagulation for primary percutaneous coronary intervention (PPCI) in a high-volume centre. Methods and results: This analysis was an open-label, prospective registry including all patients admitted to our centre for PPCI from April 2014 to April 2016. Heparin was reintroduced as standard anticoagulant in April 2015. During the 2 years, 1291 patients underwent a PPCI, 662 in the Bivalirudin protocol period (Cohort B) and 629 in the Heparin protocol period (Cohort H). Baseline and procedural characteristics were not significantly different, except for a higher use of thromboaspiration and femoral access in the earlier Cohort B. Glycoprotein 2b3a (Gp2b3a) antagonists were used in 24% of the patients in Cohort B versus 28% in Cohort H (P<0.01). We did not observe any differences in death at 180 days (11.03% in Cohort B vs 11.29% in Cohort H)(HR 95% CI 0.98 (0.72 to 1.33), P=0.88). The incidence of any bleeding complications at 30 days did not differ between the two periods (21.9% vs 21.9%, P=0.99). The cost related to the anticoagulants amounted to £246 236 in Cohort B versus £4483 in Cohort H (£324 406 vs £102 347 when adding Gp2b3a antagonists). Conclusion: We did not find clinically relevant changes in patient outcomes, including bleeding complications with reintroduction of heparin in our PPCI protocol. However, the use of heparin was associated with a major reduction in treatment costs
Ion acceleration and anomalous transport in the near wake of a plasma limiter
Ion acceleration and anomalous transport were studied experimentally in the near wake region of an electrically floating disk limiter immersed in two different types of collisionless, supersonically flowing, magnetized plasmas: the first initially quiescent, the second initially turbulent. Ion densities and velocity distributions were obtained using a nonperturbing laser induced fluorescence diagnostic. Large-amplitude, low-frequency turbulence was observed at the obstacle edge and in the wake. Rapid ion and electron configuration space transport and ion velocity space transport were observed. Configuration space and velocity space transport were similar for both quiescent and turbulent plasma-obstacle systems, suggesting that plasma-obstacle effects outweigh the effects of initial plasma turbulence levels
The Cosmic Ray Muon Flux at WIPP
In this work a measurement of the muon intensity at the Waste Isolation Pilot
Plant (WIPP) near Carlsbad, NM, USA is presented. WIPP is a salt mine with a
depth of 655 m. The vertical muon flux was measured with a two panels
scintillator coincidence setup to
Phi_{vert}=3.10(+0.05/-0.07)*10^(-7)s^(-1)cm^(-2)sr^(-1).Comment: 18 pages, p figure
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