638 research outputs found
Structural Trends Interpretation of the Metal-to-Semiconductor Transition in Deformed Carbon Nanotubes
Two mechanisms that drive metal-to-semiconductor transitions in single-walled
carbon nanotubes are theoretically analyzed through a simple tight-binding
model. By considering simple structural trends, the results demonstrate that
metal-to-semiconductor transitions can be induced more readily in metallic
zigzag nanotubes than in armchair nanotubes. Furthermore, it is shown that both
mechanisms have the effect of making the two originally equivalent sublattices
physically distinguishable.Comment: 4 pages, 4 figure
Information filtering based on transferring similarity
In this Brief Report, we propose a new index of user similarity, namely the
transferring similarity, which involves all high-order similarities between
users. Accordingly, we design a modified collaborative filtering algorithm,
which provides remarkably higher accurate predictions than the standard
collaborative filtering. More interestingly, we find that the algorithmic
performance will approach its optimal value when the parameter, contained in
the definition of transferring similarity, gets close to its critical value,
before which the series expansion of transferring similarity is convergent and
after which it is divergent. Our study is complementary to the one reported in
[E. A. Leicht, P. Holme, and M. E. J. Newman, Phys. Rev. E {\bf 73} 026120
(2006)], and is relevant to the missing link prediction problem.Comment: 4 pages, 4 figure
Development of Ultra-High Sensivity Silicon Carbide Detectors
A variety of silicon carbide (SiC) detectors have been developed to study the sensitivity of SiC ultraviolet (UV) detectors, including Schottky photodiodes, p-i-n photodiodes, avalanche photodiodes (APDs), and single photon-counting APDs. Due to the very wide bandgap and thus extremely low leakage current, Sic photo-detectors showed excellent sensitivity. The specific detectivity, D*, of SiC photodiodes are orders of magnitude higher than that of their competitors, such as Si photodiodes, and comparable to the D* of photomultiplier tubes (PMTs). To pursue the ultimate detection sensitivity, SiC APDs and single photon-counting avalanche diodes (SPADs) have also been fabricated. By operating the SiC APDs at a linear mode gain over 10(exp 6), SPADs in UV have been demonstrated. SiC UV detectors have great potential for use in solar blind UV detection and biosensing. Moreover, SiC detectors have excellent radiation hardness and high temperature tolerance which makes them ideal for extreme environment applications such as in space or on the surface of the Moon or Mars
Polymorphism in a Plasmodium falciparum Erythrocyte-binding Ligand Changes Its Receptor Specificity
Recognition of human erythrocytes by Plasmodium species depends in part on Region II of the Duffy binding-like family of parasite ligands, which includes BA erythrocyte binding ligand (BAEBL) of P. falciparum. In previous studies of BAEBL from two clones, Dd2/Nm from Vietnam and E12 from Papua New Guinea (PNG), it was found that BAEBL bound different erythrocyte receptors. Because of variation in binding specificity, we studied the sequence and erythrocyte binding specificity of Region II of BAEBL in P. falciparum clones from different parts of the world. We observed five nucleotide substitutions leading to five amino acid changes and five polymorphisms in Region II of BAEBL in parasites from both PNG and other parts of the world. We expressed four of the polymorphisms on COS cells and determined their binding to enzyme-treated erythrocytes and to Gerbich-negative erythrocytes. We also performed erythrocyte-binding assay using the native protein from radiolabeled culture supernatant. Both assays demonstrated that each of the four polymorphisms in the parasite ligand, BAEBL, bound to a different receptor on erythrocytes. These results suggest that P. falciparum has evolved multiple invasion pathways dependent on polymorphisms in the BAEBL ligand
Behaviors of susceptible-infected epidemics on scale-free networks with identical infectivity
In this article, we proposed a susceptible-infected model with identical
infectivity, in which, at every time step, each node can only contact a
constant number of neighbors. We implemented this model on scale-free networks,
and found that the infected population grows in an exponential form with the
time scale proportional to the spreading rate. Further more, by numerical
simulation, we demonstrated that the targeted immunization of the present model
is much less efficient than that of the standard susceptible-infected model.
Finally, we investigated a fast spreading strategy when only local information
is available. Different from the extensively studied path finding strategy, the
strategy preferring small-degree nodes is more efficient than that preferring
large-degree nodes. Our results indicate the existence of an essential
relationship between network traffic and network epidemic on scale-free
networks.Comment: 5 figures and 7 page
Observation of orbital ordering and origin of the nematic order in FeSe
To elucidate the origin of nematic order in FeSe, we performed
field-dependent 77Se-NMR measurements on single crystals of FeSe. We observed
orbital ordering from the splitting of the NMR spectra and Knight shift and a
suppression of it with magnetic field B0 up to 16 T applied parallel to the
Fe-planes. There is a significant change in the distribution and magnitude of
the internal magnetic field across the orbital ordering temperature Torb while
stripe-type antiferromagnetism is absent. Giant antiferromagnetic (AFM) spin
fluctuations measured by the NMR spin-lattice relaxation are gradually
developed starting at ~ 40 K, which is far below the nematic ordering
temperature Tnem. These results demonstrate that orbital ordering is the origin
of the nematic order, and the AFM spin fluctuation is the driving mechanism of
superconductivity in FeSe under the presence of the nematic order.Comment: 6 pages, 4 figure
DNA Methylation Signatures within the Human Brain
DNA methylation is a heritable modification of genomic DNA central to development, imprinting, transcriptional regulation, chromatin structure, and overall genomic stability. Aberrant DNA methylation of individual genes is a hallmark of cancer and has been shown to play an important role in neurological disorders such as Rett syndrome. Here, we asked whether normal DNA methylation might distinguish individual brain regions. We determined the quantitative DNA methylation levels of 1,505 CpG sites representing 807 genes with diverse functions, including proliferation and differentiation, previously shown to be implicated in human cancer. We initially analyzed 76 brain samples representing cerebral cortex (n=35), cerebellum (n=34), and pons (n=7), along with liver samples (n=3) from 43 individuals. Unsupervised hierarchical analysis showed clustering of 33 of 35 cerebra distinct from the clustering of 33 of 34 cerebella, 7 of 7 pons, and all 3 livers. By use of comparative marker selection and permutation testing, 156 loci representing 118 genes showed statistically significant differences—a ⩾17% absolute change in DNA methylation (P<.004)—among brain regions. These results were validated for all six genes tested in a replicate set of 57 samples. Our data suggest that DNA methylation signatures distinguish brain regions and may help account for region-specific functional specialization
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