21,306 research outputs found
THE VERTICAL COORDINATION CONTINUUM AND THE DETERMINANTS OF FIRM-LEVEL COORDINATION STRATEGY
A number of past authors have argued that vertical coordination strategies lie along a continuum running from spot markets to vertical integration. However, the strategies that make up the middle of this continuum have remained ill defined and the sense in which the continuum is truly a continuum has not been made specific. This paper attempts to define the continuum and its "middle" strategies in such a manner that the continuum is truly a continuum has not been made specific. This paper attempts to define the continuum and its "middle" strategies in such a manner that the continuum becomes a useful means by which firm-level decision makers could examine their options for vertical coordination strategy.Industrial Organization,
STRATEGIC CHOICE ALONG THE VERTICAL COORDINATION CONTINUUM
Fundamental changes are underway in the U.S. agri-food system, changes that are altering traditional marketing relationships. Parts of the food system are becoming tightly integrated, such as the poultry subsector and, increasingly, the pork subsector. The tightening of vertical linkages has been characterized by movement from open markets to various forms of managed coordination, e.g. contracting, strategic alliances, and single ownership of multiple market stages. 1998 AAEA SymposiumIndustrial Organization,
Quantifying Strategic Choice Along the Vertical Coordination Continuum
The qualitative and quantitative results of a study undertaken to test a decision framework firms might consider in choosing a vertical coordination strategy are presented. The posited five-step decision making process tested that a change in coordination strategy would occur if and only if a "yes" decision was made at each step. The results reported as case-based frequencies and as a discriminate analysis function provide strong support for the study's research propositions. The ability of an alternative to reduce the costliness of a coordination error and the acceptability of the risk/return tradeoff were critical to the willingness of a sample of producers to change coordination strategy. Implementability was significant, but not to the same extent as costliness of a coordination error or acceptability of the risk/return tradeoff.vertical coordination, vertical coordination continuum, discriminate analysis, willingness to change, unwillingness to change, coordination error, programmability, implementability, risk/return tradeoff, Industrial Organization,
Optical Continuum and Emission-Line Variability of Seyfert 1 Galaxies
We present the light curves obtained during an eight-year program of optical
spectroscopic monitoring of nine Seyfert 1 galaxies: 3C 120, Akn 120, Mrk 79,
Mrk 110, Mrk 335, Mrk 509, Mrk 590, Mrk 704, and Mrk 817. All objects show
significant variability in both the continuum and emission-line fluxes. We use
cross-correlation analysis to derive the sizes of the broad Hbeta-emitting
regions based on emission-line time delays, or lags. We successfully measure
time delays for eight of the nine sources, and find values ranging from about
two weeks to a little over two months. Combining the measured lags and widths
of the variable parts of the emission lines allows us to make virial mass
estimates for the active nucleus in each galaxy. The virial masses are in the
range 10^{7-8} solar masses.Comment: 24 pages, 16 figures. Accepted for publication in Ap
Feasibility study for a scanning celestial attitude determination system SCADS on the IMP spacecraft Final report
System design analysis to establish feasibility of using electro-optical celestial scanning sensor on IMP spacecraft for determination of spacecraft attitude by star measurement
Zero-point energy of massless scalar fields in the presence of soft and semihard boundaries in D dimensions
The renormalized energy density of a massless scalar field defined in a
D-dimensional flat spacetime is computed in the presence of "soft" and
"semihard" boundaries, modeled by some smoothly increasing potential functions.
The sign of the renormalized energy densities for these different confining
situations is investigated. The dependence of this energy on for the cases
of "hard" and "soft/semihard" boundaries are compared.Comment: 36 pages, LaTeX, 4 figure
Integration of microarray analysis into the clinical diagnosis of hematological malignancies: How much can we improve cytogenetic testing?
PurposeTo evaluate the clinical utility, diagnostic yield and rationale of integrating microarray analysis in the clinical diagnosis of hematological malignancies in comparison with classical chromosome karyotyping/fluorescence in situ hybridization (FISH).MethodsG-banded chromosome analysis, FISH and microarray studies using customized CGH and CGH+SNP designs were performed on 27 samples from patients with hematological malignancies. A comprehensive comparison of the results obtained by three methods was conducted to evaluate benefits and limitations of these techniques for clinical diagnosis.ResultsOverall, 89.7% of chromosomal abnormalities identified by karyotyping/FISH studies were also detectable by microarray. Among 183 acquired copy number alterations (CNAs) identified by microarray, 94 were additional findings revealed in 14 cases (52%), and at least 30% of CNAs were in genomic regions of diagnostic/prognostic significance. Approximately 30% of novel alterations detected by microarray were >20 Mb in size. Balanced abnormalities were not detected by microarray; however, of the 19 apparently "balanced" rearrangements, 55% (6/11) of recurrent and 13% (1/8) of non-recurrent translocations had alterations at the breakpoints discovered by microarray.ConclusionMicroarray technology enables accurate, cost-effective and time-efficient whole-genome analysis at a resolution significantly higher than that of conventional karyotyping and FISH. Array-CGH showed advantage in identification of cryptic imbalances and detection of clonal aberrations in population of non-dividing cancer cells and samples with poor chromosome morphology. The integration of microarray analysis into the cytogenetic diagnosis of hematologic malignancies has the potential to improve patient management by providing clinicians with additional disease specific and potentially clinically actionable genomic alterations
Altered Fungal Morphogenesis During Early Stages of Ectomycorrhiza Formation in Eucalyptus Pilularis
Scanning electron microscopy (SEM) of Eucalyptus pilularis roots inoculated with Pisolithus tinctorius, under controlled conditions, revealed altered morphogenesis of fungal hyphae in contact with the root surface. These changes occurred prior to the formation of a full fungal mantle and resulted in the formation of a compact fungal layer as a consequence of fusion of proliferating, branching hyphae. Although similar growth patterns have been observed in the inner mantle of fully developed ectomycorrhizae using contrast interference microscopy, this is the first time this feature has been observed during early mantle formation using SEM. Changes in fungal morphology during early stages of colonization may be correlated with recognition between the symbionts, and the subsequent establishment of a symbiotic relationship between compatible partners
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