9,056 research outputs found
Audio Features Affected by Music Expressiveness
Within a Music Information Retrieval perspective, the goal of the study
presented here is to investigate the impact on sound features of the musician's
affective intention, namely when trying to intentionally convey emotional
contents via expressiveness. A preliminary experiment has been performed
involving tuba players. The recordings have been analysed by extracting a
variety of features, which have been subsequently evaluated by combining both
classic and machine learning statistical techniques. Results are reported and
discussed.Comment: Submitted to ACM SIGIR Conference on Research and Development in
Information Retrieval (SIGIR 2016), Pisa, Italy, July 17-21, 201
Strong dust processing in circumstellar discs around 6 RV Tauri stars. Are dusty RV Tauri stars all binaries?
We present extended Spectral Energy Distributions (SEDs) of seven classical
RV Tauri stars, using newly obtained submillimetre continuum measurements and
Geneva optical photometry supplemented with literature data. The broad-band
SEDs show a large IR excess with a black-body slope at long wavelengths in six
of the seven stars, R Sct being the noticeable exception. This long wavelength
slope is best explained assuming the presence of a dust component of large
grains in the circumstellar material. We show that the most likely distribution
of the circumstellar dust around the six systems is that the dust resides in a
disc. Moreover, very small outflow velocities are needed to explain the
presence of dust near the sublimation temperature and we speculate that the
discs are Keplerian. The structure and evolution of these compact discs are as
yet not understood but a likely prerequisite for their formation is that the
dusty RV Tauri stars are binaries.Comment: 10 pages, will be published in A&
Matrix-free calcium in isolated chromaffin vesicles
Isolated secretory vesicles from bovine adrenal medulla contain 80 nmol of Ca2+ and 25 nmol
of Mg2+ per milligram of protein. As determined with a Ca2+-selective electrode, a further accumulation
of about 160 nmol of Ca2+/mg of protein can be attained upon addition of the Ca2+ ionophore A23187.
During this process protons are released from the vesicles, in exchange for Ca2+ ions, as indicated by the
decrease of the pH in the incubation medium or the release of 9-aminoacridine previously taken up by the
vesicles. Intravesicular Mg2+ is not released from the vesicles by A23 187, as determined by atomic emission
spectroscopy. In the presence of N H Q , which causes the collapse of the secretory vesicle transmembrane
proton gradient (ApH), Ca2+ uptake decreases. Under these conditions A23 187-mediated influx of Ca2+
and efflux of H+ cease at Ca2+ concentrations of about 4 pM. Below this concentration Ca2+ is even released
from the vesicles. At the Ca2+ concentration at which no net flux of ions occurs the intravesicular matrix
free Ca2+ equals the extravesicular free Ca2+. In the absence of NH4C1 we determined an intravesicular
pH of 6.2. Under these conditions the Ca2+ influx ceases around 0.15 pM. From this value and the known
pH across the vesicular membrane an intravesicular matrix free Ca2+ concentration of about 24 pM was
calculated. This is within the same order of magnitude as the concentration of free Ca2+ in the vesicles
determined in the presence of NH4C1. Calculation of the total Ca2+ present in the secretory vesicles gives
an apparent intravesicular Ca2+ concentration of 40 mM, which is a factor of lo4 higher than the free
intravesicular concentration of Ca2+. It can be concluded, therefore, that the concentration gradient of free
Ca2+ across the secretory vesicle membrane in the intact chromaffin cells is probably small, which implies
that less energy is required to accumulate and maintain Ca2+ within the vesicles than was previously
anticipated
Hard Instances of the Constrained Discrete Logarithm Problem
The discrete logarithm problem (DLP) generalizes to the constrained DLP,
where the secret exponent belongs to a set known to the attacker. The
complexity of generic algorithms for solving the constrained DLP depends on the
choice of the set. Motivated by cryptographic applications, we study sets with
succinct representation for which the constrained DLP is hard. We draw on
earlier results due to Erd\"os et al. and Schnorr, develop geometric tools such
as generalized Menelaus' theorem for proving lower bounds on the complexity of
the constrained DLP, and construct sets with succinct representation with
provable non-trivial lower bounds
Zeros of the i.i.d. Gaussian power series: a conformally invariant determinantal process
Consider the zero set of the random power series f(z)=sum a_n z^n with i.i.d.
complex Gaussian coefficients a_n. We show that these zeros form a
determinantal process: more precisely, their joint intensity can be written as
a minor of the Bergman kernel. We show that the number of zeros of f in a disk
of radius r about the origin has the same distribution as the sum of
independent {0,1}-valued random variables X_k, where P(X_k=1)=r^{2k}. Moreover,
the set of absolute values of the zeros of f has the same distribution as the
set {U_k^{1/2k}} where the U_k are i.i.d. random variables uniform in [0,1].
The repulsion between zeros can be studied via a dynamic version where the
coefficients perform Brownian motion; we show that this dynamics is conformally
invariant.Comment: 37 pages, 2 figures, updated proof
Exploring differential item functioning in the SF-36 by demographic, clinical, psychological and social factors in an osteoarthritis population
The SF-36 is a very commonly used generic measure of health outcome in osteoarthritis (OA). An important, but frequently overlooked, aspect of validating health outcome measures is to establish if items work in the same way across subgroup of a population. That is, if respondents have the same 'true' level of outcome, does the item give the same score in different subgroups or is it biased towards one subgroup or another. Differential item functioning (DIF) can identify items that may be biased for one group or another and has been applied to measuring patient reported outcomes. Items may show DIF for different conditions and between cultures, however the SF-36 has not been specifically examined in an osteoarthritis population nor in a UK population. Hence, the aim of the study was to apply the DIF method to the SF-36 for a UK OA population. The sample comprised a community sample of 763 people with OA who participated in the Somerset and Avon Survey of Health. The SF-36 was explored for DIF with respect to demographic, social, clinical and psychological factors. Well developed ordinal regression models were used to identify DIF items. Results: DIF items were found by age (6 items), employment status (6 items), social class (2 items), mood (2 items), hip v knee (2 items), social deprivation (1 item) and body mass index (1 item). Although the impact of the DIF items rarely had a significant effect on the conclusions of group comparisons, in most cases there was a significant change in effect size. Overall, the SF-36 performed well with only a small number of DIF items identified, a reassuring finding in view of the frequent use of the SF-36 in OA. Nevertheless, where DIF items were identified it would be advisable to analyse data taking account of DIF items, especially when age effects are the focus of interest
From one cell to the whole froth: a dynamical map
We investigate two and three-dimensional shell-structured-inflatable froths,
which can be constructed by a recursion procedure adding successive layers of
cells around a germ cell. We prove that any froth can be reduced into a system
of concentric shells. There is only a restricted set of local configurations
for which the recursive inflation transformation is not applicable. These
configurations are inclusions between successive layers and can be treated as
vertices and edges decorations of a shell-structure-inflatable skeleton. The
recursion procedure is described by a logistic map, which provides a natural
classification into Euclidean, hyperbolic and elliptic froths. Froths tiling
manifolds with different curvature can be classified simply by distinguishing
between those with a bounded or unbounded number of elements per shell, without
any a-priori knowledge on their curvature. A new result, associated with
maximal orientational entropy, is obtained on topological properties of natural
cellular systems. The topological characteristics of all experimentally known
tetrahedrally close-packed structures are retrieved.Comment: 20 Pages Tex, 11 Postscript figures, 1 Postscript tabl
Agonist-stimulated release of von Willebrand factor and procoagulant factor VIII in rats with and without risk factors for stroke [Research Report]
Lipopolysaccharidc (LPS)-induced (i.v. or i.c.v., 1.8 mg/kg) release of von Willebrand factor (vWF) ·was examined in spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto (WKY) rats. SHR rats releascd significantly (P < 0.05) more vWF than WKY rats in response to LPS. LPS also inhibited factor VIII procoagulant activity (FVIII: c) which may indicate an increase in thrombin activity. Cultured cerebrovascular endothelial cells (EC) derived from both SHR and WKY rats, as weil as human umbilical vein EC (HUVEC) cultures constitutively released vWF. Treatment with agonists including LPS, thrombin and tumor necrosis factor-a (TNFa) did not affect the in vitro secretion of vWF by cerebrovascular EC cultures but significantly upregulated vWF release by HUVEC cultur~s. Preincubation of cerebrovascular EC cultures with interleukin-1 OL-l) ± TNFa or co-culturing in the presence of LPS-activated syngeneic monocytes had no effect on vWF secretion. The findings demoostrate that conditions of hypertension may affect endothelial cells and make them more responsive to agonist Stimulation and thereby increase secretion of vWF, an important factqr in hemostasis as weil as thrombosis. The capacity of LPS to significantly affect the in vivo secretion of vWF in SHR and WKY rats but not cultured cerebrovascular EC indicates that observed elevations in plasma vWF were not derived from cerebrovascular EC. lt is suggested that hypertension may function as a risk factor for thrombotic stroke by influencing factors involved in coagulation processes, such as vWF and factor VIII : c
Quadratic optimal functional quantization of stochastic processes and numerical applications
In this paper, we present an overview of the recent developments of
functional quantization of stochastic processes, with an emphasis on the
quadratic case. Functional quantization is a way to approximate a process,
viewed as a Hilbert-valued random variable, using a nearest neighbour
projection on a finite codebook. A special emphasis is made on the
computational aspects and the numerical applications, in particular the pricing
of some path-dependent European options.Comment: 41 page
Analytical results for string propagation near a Kaluza-Klein black hole
This brief report presents analytical solutions to the equations of motion of
a null string. The background spacetime is a magnetically charged Kaluza-Klein
black hole. The string coordinates are expanded with the world-sheet velocity
of light as an expansion parameter. It is shown that the zeroth order solutions
can be expressed in terms of elementary functions in an appropriate large
distance approximation. In addition, a class of exact solutions corresponding
to the Pollard-Gross-Perry-Sorkin monopole case is also obtained.Comment: Revtex, 9 pages including two postscript figures, More detailed
discussion and new references adde
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