56 research outputs found
Influence of millimeter electromagnetic waves on the functional capabilities of the lower limb muscles in athletes - volleyball players
The authors, when observing 22 athletes - volleyball players of different volleyball specialization, assessed the effect of millimeter electromagnetic waves (EMW) on the functional state of the muscular system of the lower extremities. The electromagnetic effect was carried out using the "Complex SP 80" apparatus (frequencies 3900 - 4120 kHz were used). Electrodes were applied to the muscles of the thigh and lower leg, sinusoidal discharges were applied for 10 seconds during the strength training period. The results of observations showed that under the influence of EME, the height of the jump increases by 7%, due to the increase in the energy of the jump and its intensity. The release of the activity of the knee joint is also noted. The authors believe that under the influence of EME, the transmission of regulatory impulses in neuromuscular contact improves, which contributes to the synchronization and strength of contractions of the muscle fiber bundles. Also, under the influence of EMW, blood microcirculation in the muscle improves
Perspectiveness of correction of accompanying diseases in patients with autism by course of interior use of naturally low mineralized water
The article reviews the pathogenesis and the course of autism. Authors define autism as a psychosomatic disorder. A distinctive feature of mineral waters, as natural therapeutic factors of weak intensity, is their pronounced biological activity, the absence of side effects and the possibility of long-term use in combination with medication therapy. The paper presents data substantiating the possibility of using mineral water with an increased content of organic substances for the correction of the somatic component of autism (problems of the gastrointestinal tract, carbohydrate metabolism disorders, neurosis)
Comparative evaluation of the effectiveness of natural silicon mineral waters and their artificial analogics on the current experimental patiology of sleeve-surface tract
The article presents data on the effect of silicon-containing mineral waters (MW) and their artificial analogues with the corresponding content of metasilicic acid on the state of the stomach wall in the modeling of gastritis in white rats. It was established that the use of MW with different content of metasilicic acid has a unidirectional, positive effect on the course of gastritis. MW with greater mineralization, molarity and high content of methacrylic acid completely eliminate inflammation and moderately stimulate reparative processes.
In the application of MW with less mineralization, molarity and lower content of metasilicic acid, there were definitive inflammation manifestations, but the manifestations of reparative processes were more pronounced. The same trend was observed with the use of artificial analogues - model solutions on distilled water with the corresponding content of metasilicic acid. It is determined the same restorative in the direction, but much weaker corrective effect than the corresponding MW. The important component of the corrective action of these silicon MW when used in animals with gastritis is determined by the peculiarities of the macro component composition and the proportion of the main macro components - Na +, K +, Mg2 +, Ca2 +, НСО3, Cl-, SO42- and, to a lesser extent, silicon content
Study of the effect of external use of a brown algae product on the structural-functional continuum
Nasibullin B. A., Gushcha S. G., Dekhtyar Yu. N., Volyanska V. S. Study of the effect of external use of a brown algae product on the structural-functional continuum. Journal of Education, Health and Sport. 2023;47(1):75-83. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2023.47.01.007
https://apcz.umk.pl/JEHS/article/view/46248
https://zenodo.org/record/8364684
The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of 17.07.2023 No. 32318.
Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences).
Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 17.07.2023 Lp. 32318. Posiada Unikatowy Identyfikator Czasopisma: 201159.
Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu).
© The Authors 2023;
This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access.
This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited.
This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper.
Received: 29.07.2023. Revised:21.08.2023. Accepted: 28.08.2023. Published: 29.08.2023.
Study of the effect of external use of a brown algae product on the structural-functional continuum
B. A. Nasibullin, S. G. Gushcha, Yu. N. Dekhtyar, V. S. Volyanska
State Institution «Ukrainian Research Institute of Medical Rehabilitation and Resort Therapy of the Ministry of Health of Ukraine», Odesa, Ukraine
Boris Nasibullin: ORCID https://orcid.org/0000-0003-3963-2374; e-mail: [email protected]
Sergey Gushcha: ORCID https://orcid.org/0000-0003-3097-5258; e-mail: [email protected]
Veronika Volyanska: ORCID https://orcid.org/0000-0002-3019-7620; e-mail: [email protected]
Abstract
The authors, in a study on 25 outbred Wistar white rats weighing 180-200 g, determined the effect of Lamidana (a product from sea brown algae) on the structural-functional continuum, that is, the correlation of the functional activity of the liver parenchyma and its structural characteristics. Methods. The detoxifying function of the liver was studied by the duration of sleep of animals due to the action of anesthesia - intraperitoneal administration of sodium thiopental (estimate the rate of metabolism of thiopental, carried out by the cytochrome-P-450-dependent monooxygenase system of hepatocytes). The structural and functional state of the liver parenchyma was assessed according to the study of histological preparations. The results of the studies showed that under the influence of the external application of "Lamidin" in the test rats, the liver1s detoxification function is enhanced (significantly significant decrease in the duration of sleep of animals). At the same time, structural signs of increased functional activity of hepatocytes are determined in the parenchyma. Conclusions. The authors believe that "Lamidan", due to the peculiarities of its chemical composition, enhances the metabolic and functional activity of hepatocytes but does not damage the correlative relationships between the structure and function of hepatocytes.
Keywords: product from brown algae; liver; structural-functional continuum
Influence of mineral water on the structural and functional state of the rats kidneys with metabolic syndrome
In white rats in the setting of development of metabolic syndrome inhibition of
the urinary and excretory functions of the kidney, with impaired water-ion
balance (the kidneys excrete slightly hyperosmotic urine in a small amount) on
the background of structural signs of dystrophies. Daily diuresis is reduced by
37% due to a decrease in glomerular filtration rate (GFR) by 22% and an
increase in the percentage of tubular reabsorption (p <0.001), excretion of
creatinine, urea and chloride decreased by 22%, 15% and 56%. The excretion of potassium and sodium ions increases by 14% and 38%, respectively. The daily
urine is greatly delayed. Two-week internal course administration of lowmineralized sodium chloride water has a positive effect on impaired renal
function: the volume of diuresis is increased by 15% by accelerating GFR by
20% and restoring the value of tubular reabsorption. Creatinine excretion is
increased by 20% and urea by 32%. The excretion of potassium and sodium ions
is increased by 50% and 166%, respectively.
Excretion of chloride ions and urine pH is fully restored. Microscopically
determined residual manifestations of dystrophic processes in the kidneys,
which against the background of the recovery of processes of urination and
stimulation of ion-regulating and excretory functions of the kidneys, indicates
the ability of the applied sodium chloride MW to correct the structural and
functional disorders of the metabolic syndrome
Evaluation of the influence of Chloride Sodium rape on the external application on the structural and functional condition of red kidney on development
Much attention has been paid to the study of the numerous effects of chronic stress and the methods of their
correction, but some questions remain unanswered. Goal. To investigate the effect of highly mineralized sodium
chloride mineral water (brine) on the structural and functional state of rat kidneys with experimental distress.
White female rats weighing 180 - 220 g were ranked into three groups: group I intact rats (control), group II rats
with a distress model (duration 30 days); group III - rats with a model of distress, who from 15 to 30 day of
experiment received a course of external procedures with rapes. In group II rats, the development of distress
caused dystrophic changes in the kidneys, which led to inhibition of their urinary, ion-regulating and excretory
functions. To correct the manifestations of distress rats received a course of external procedures with brine (5
procedures for 2 hours a day). Renal function restored: GFR exceeds group I data by 30%, resulting in complete
recovery of the diuresis. Urea excretion is restored, and creatinine excretion exceeds the control level by 30% (p
<0.001). The concentration of potassium ions is restored to the control level, their excretion is reduced by 20%,
and the urinary excretion of sodium and chloride ions is increased by — 90% and 57%. Microscopically — the
structure of nephrons and their components without visual changes, that is, does not differ from the first group of
rats. Conclusions. Studies have shown that with transdermal administration of sodium chloride brine has a
significant protective effect on the course of pathological changes in the function of the kidney of rats against the
background of the development of distress
Clinical and experimental substantiation of the use of bentonite suspension in the complex rehabilitation of patients with chronic viral hepatitis C with concomitant non-alcoholic fatty liver disease
One of the most severe diffuse liver diseases is chronic viral hepatitis C (CHC) combined with non-alcoholic fatty
liver disease (NAFLD). After completing the treatment of CHC with drugs of direct antiviral action, there remains a high risk of
further progression of liver fibrosis associated with the presence of comorbid pathology - NAFLD in patients. The above
circumstances initiated us to search for new non-drug technologies to treat this category of patients. Purpose of the work: to study
the effectiveness of use bentonite suspension in rats with a model of NAFLD and to substantiate the practicality of using bentonite
in the complex treatment of CHC patients with concomitant NAFLD. Methods: experimental, anamnestic and clinical, general
clinical, biochemical, determination of the HOMA index, leptin and adiponectin levels, ultrasonographic studies of the digestive
system, bacteriological examination of feces, statistical methods.Results: According to microscopic examination, bentonite
application in animals with the NAFLC model leads to a decrease in liver steatosis, restoration of bile formation and bile secretion,
and protein-synthesizing liver function. In the blood, there was a positive dynamics to the restoration of energy-dependent
transmembrane ion transport according to the activity of Na+/K+ -ATPase and Mg2+/Ca2+ -ATPase (in the liver tissue) and the
balance of the antioxidant system (to restrain malondialdehyde and catalase activity). We examined 40 patients with CHC with
concomitant NAFLD, who completed the course of antiviral therapy (AVT) and were divided into two groups. 1 (control) group (20
people) received a basic treatment complex (diet therapy, which corresponded to the Mediterranean diet, a regimen of dosed
physical exertion, patients of 2 groups (20 people, the main group) additionally received a preparation based on bentonite clay inside
- 10 days (1 dose three times a day) Evaluation of the effectiveness of treatment was carried out one month after the start of
treatment. Conclusion: The treatment carried out in both groups was accompanied by positive dynamics in most of the diseaseʹs
symptoms. But a significant advantage was observed in the second group, where the normalization of cholestatic and dyslipidemic
syndromes was established, that is, the effect on the pathogenetic links of the progression of NAFLD was proved. The results
obtained confirm the practicality of using the drug with bentonite in the complex treatment of CHC patients with concomitant
NAFLD
Experience with the use of oral probiotic Streptococcus salivarius K12 for the prevention of recurrence of pharyngotonsillar
Relevance. Pharyngotonsillitis (PhT) is one of the most common recurrent upper respiratory tract diseases. Viruses are the most common cause of disease (Respiratory viruses, Enterov iruses, Herpesviruses), 30% are of bacterial origin. The most serious types of PhT are associated with group of β-hemolytic streptococcus (GAS) - Streptococcus pyogenes, in which antibiotic therapy is the first choice of therapy. In order to reduce the use of antibiotics, to prevent relapses of pharyngotonsillar episodes, a specific probiotic therapy was carried out using Streptococcuss alivarius K12 (SsK12). K12 (SsK12) is a probiotic strain that inhibits the growth of Streptococcus pyogenes, Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis in vitro. Materials and methods. A study was conducted in 90 patients with recurrent pharyngotonsillitis (PhT) of bacterial origin, in whom Streptococcus pyogenes was isolated during bacteriolog ical examination. The course of treatment for patients of all groups was 30 days. Patients of group 1 (30 people) were treated with standard methods. In 30 patients of group 2 (30 people), in addition to standard therapy, the respiratory probiotic "Bactoblis" was used for a course of 30 days. In 30 patients of group 3, standard therapy was carried out with the use of the respiratory probiotic drug "Bactoblis" and additional sanitation of the lacunae of the palatine tonsils by vacuum extraction. As a result, in patients of groups 2 and 3, the frequency of PhT episodes significantly decreased, and the use of antibiotics decreased too. The most persistent effect of treatment was in patients of group 3 - the quality of treatment and prevention increased, the number of exacerbations decreased, the severity of clinical manifestations, and the drug load decreased. Individual intolerance to the components of the drug has not been identified. However, 6 months after the observation was started, the clinical and laboratory parameters of the main groups began to deteriorate, approaching those of the control group, and more stable therapeutic effect was observed in patients of group 3. Conclusions. The authors consider it expedient to perform tonsil sanitation twice a year, with further use of the drug "Bactoblis" in patients suffering from PhT. All human studies were conducted in compliance with the rules of the Helsinki Declaration of the World Medical Association "Ethical principles of medical research with human participation as an object of study". Informed consent was obtained from all participants
Investigation of the influence of mineral water with increased content of organic on the development of metabolic syndrome in the experiment
Background: The World Health Organization describes the metabolic syndrome (MS) as a "21st
Century Pandemic." The pathogenesis of MS is complex and completely not studied, which justifies the
importance of conducting research in this field, including experimental ones. Recently, in order to treat
MS and its complications, along with drug therapy, non-pharmacological agents are used - natural
therapeutic resources, which include mineral water (MW). MW are widely used in medical practice,
due to the possibility of prolonged use, the combination of general non-specific effects on the processes
of body sanogenesis in general and local pathogenetic mechanisms.
Objective: To investigate the effect of MW with increased content of organic substances on its internal
application to the metabolic rate of experimental animals with the MS.
Materials and Methods: In the experiment, 40 white male rats weighing 230.0 – 250.0 g were used.
For reproduction of the MS model, the animals were kept for 60 days in a standard diet, while the rats
additionally received 30 grams of white bread crumbs per animal and consumed only 10% fructose
solution in distilled water (as a drinking liquid). MW was injected into the esophagus of animals with a
soft probe with olive, once a day for 12 consecutive days, at a dose of 1% of the body weight of the
animal.
Results: At day 60 of the experiment in rats with MS, blood glucose levels were increased by 3 mmol/l
(p < 0,01), cholesterol and triglycerides by 32 and 154% (p < 0.01). Weight of animals increased by
14% (p < 0,01), and the use of a solution of fructose by 100%. Under the influence of MW, the weight
of animals decreased by 8% (p < 0.01), the use of a solution of fructose by 50% (р < 0,01). The level of
glucose decreased by 2 mmol/l, the cholesterol content was completely restored (p > 0,5), and the
content of triglycerides remained elevated (p < 0,001).
Conclusion: MS is a serious and long-lasting pathology, its development causes serious rearrangements
in the body. Established corrective effect of MW with increased content of organic substances on
separate parts of pathogenesis of MS, although not carried out in full, but is of a stable nature
Assessment of the influence of natrium chloride water on the course of toxic liver damage in the experiment
The paper presents data on the evaluation of the effectiveness of the use of natural chloride natrium
mineralized water (MW) on the condition of the body of rats with alcohol intoxication (AI). Alcoholization lasted
30 days. From 15 to 30 days, the animals received MW. The use of MW in rats on the background of the
development of AI had a positive effect on the state of metabolism: the processes of reamination, protein
metabolism, energy-dependent transmembrane transport were restored, there was a decrease in the
manifestations of hypoxic nature; the activity of endogenous detoxification processes increased and the state in
the system of lipid peroxidation and antioxidant protection was restored. Microscopically, the liver parenchyma
has improved (lipid and hyaline inclusions disappear, blood circulation increases, dystrophy is reduced ). The
obtained data show that the use of sodium chloride MW has a protective effect on the structural and functional
state and metabolic parameters of the rats liver
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