IdM@tI: Red de Innovación Docente en Materiales Interuniversitaria

IdM@ti es una red interuniversitaria formada por profesores de ciencia e ingeniería de materiales de varias universidades del estado español, comprometidos con la innovación docente. Se describe su origen, motivación y objetivos así como las actividades que ha realizado hasta el momento y los retos que se marca para el futuro

Microtubule Actin Crosslinking Factor 1 Regulates the Balbiani Body and Animal-Vegetal Polarity of the Zebrafish Oocyte

Although of fundamental importance in developmental biology, the genetic basis for the symmetry breaking events that polarize the vertebrate oocyte and egg are largely unknown. In vertebrates, the first morphological asymmetry in the oocyte is the Balbiani body, a highly conserved, transient structure found in vertebrates and invertebrates including Drosophila, Xenopus, human, and mouse. We report the identification of the zebrafish magellan (mgn) mutant, which exhibits a novel enlarged Balbiani body phenotype and a disruption of oocyte polarity. To determine the molecular identity of the mgn gene, we positionally cloned the gene, employing a novel DNA capture method to target region-specific genomic DNA of 600 kb for massively parallel sequencing. Using this technique, we were able to enrich for the genomic region linked to our mutation within one week and then identify the mutation in mgn using massively parallel sequencing. This is one of the first successful uses of genomic DNA enrichment combined with massively parallel sequencing to determine the molecular identity of a gene associated with a mutant phenotype. We anticipate that the combination of these technologies will have wide applicability for the efficient identification of mutant genes in all organisms. We identified the mutation in mgn as a deletion in the coding sequence of the zebrafish microtubule actin crosslinking factor 1 (macf1) gene. macf1 is a member of the highly conserved spectraplakin family of cytoskeletal linker proteins, which play diverse roles in polarized cells such as neurons, muscle cells, and epithelial cells. In mgn mutants, the oocyte nucleus is mislocalized; and the Balbiani body, localized mRNAs, and organelles are absent from the periphery of the oocyte, consistent with a function for macf1 in nuclear anchoring and cortical localization. These data provide the first evidence for a role for spectraplakins in polarization of the vertebrate oocyte and egg

El Aprendizaje Servicio en los grados de ingeniería: abriendo el entorno a la Universidad

El presente trabajo pretende mostrar cómo el Aprendizaje Servicio (APS) es una herramienta que permite trabajar la competencia de compromiso social en el marco de los estudios de Grado en Ingeniería. Además, se reflexiona sobre la posibilidad de implementar este tipo de actividades en asignaturas de grado. Para ello, presentamos dos proyectos que se han liderado desde la Universitat Jaume I (UJI) de Castellón durante el presente curso y se analiza la viabilidad de los mismos, así como los resultados obtenidos. El primero de los proyectos, es una experiencia de APS que se trabaja junto con la metodología del Aprendizaje Basado en Proyectos (ABP). En esta iniciativa se implican diferentes asignaturas del ámbito de la ciencia de los materiales de tres universidades públicas españolas y tres grados distintos. El segundo proyecto es una experiencia llevada a cabo por estudiantado de tres grados de Ingeniería diferentes pero de una misma facultad durante su Trabajo Fin de Grado, en el marco de un Proyecto de Cooperación Universitaria al Desarrollo entre la UJI y la Bahir Dar University en la región de Amhara, Etiopía. Los resultados muestran la gran satisfacción de todos los implicados en estas experiencias

Social media in undergraduate medical education: A systematic review.

INTRODUCTION: There are over 3.81 billion worldwide active social media (SoMe) users. SoMe are ubiquitous in medical education, with roles across undergraduate programmes, including professionalism, blended learning, well being and mentoring. Previous systematic reviews took place before recent explosions in SoMe popularity and revealed a paucity of high-quality empirical studies assessing its effectiveness in medical education. This review aimed to synthesise evidence regarding SoMe interventions in undergraduate medical education, to identify features associated with positive and negative outcomes. METHODS: Authors searched 31 key terms through seven databases, in addition to references, citation and hand searching, between 16 June and 16 July 2020. Studies describing SoMe interventions and research on exposure to existing SoMe were included. Title, abstract and full paper screening were undertaken independently by two reviewers. Included papers were assessed for methodological quality using the Medical Education Research Study Quality Instrument (MERSQI) and/or the Standards for Reporting Qualitative Research (SRQR) instrument. Extracted data were synthesised using narrative synthesis. RESULTS: 112 studies from 26 countries met inclusion criteria. Methodological quality of included studies had not significantly improved since 2013. Engagement and satisfaction with SoMe platforms in medical education are described. Students felt SoMe flattened hierarchies and improved communication with educators. SoMe use was associated with improvement in objective knowledge assessment scores and self-reported clinical and professional performance, however evidence for long term knowledge retention was limited. SoMe use was occasionally linked to adverse impacts upon mental and physical health. Professionalism was heavily investigated and considered important, though generally negative correlations between SoMe use and medical professionalism may exist. CONCLUSIONS: Social media is enjoyable for students who may improve short term knowledge retention and can aid communication between learners and educators. However, higher-quality study is required to identify longer-term impact upon knowledge and skills, provide clarification on professionalism standards and protect against harms

The oxidative dehydrogenation of propane over potassium-promoted molybdenum oxide/sol-gel zirconia catalysts

The effect of potassium loading on the structural and catalytic properties of MoOx/ZrO2 catalysts for oxidative dehydrogenation of propane was investigated. Catalysts have been prepared by modified sol-gel method, and they were characterized by nitrogen physisorption, XRD, FT-Raman spectroscopy, XPS and temperature-programmed reduction (TPR). Catalytic activity measurements have been carried out between 400 and 530degreesC under atmospheric pressure. It was observed that potassium addition prevented crystalline Zr(MoO4)(2) formation, suppressing the interaction of molybdenum oxide and zirconia phases, and it also favored the formation of three-dimensional molybdenum oxide and two-dimensional polymolybdates. Both propylene selectivity and yield were enhanced with a certain amount of potassium addition. (C) 2004 Elsevier B.V. All rights reserved