Successful management of ruptured ovarian ectopic pregnancy: a case report

Ovarian pregnancy is one of the rarest sites of non-tubal ectopic pregnancy. It has a prevalence of 0.5-3.5% in all ectopic pregnancies. It usually presents with rupture in the first trimester, a potential life-threatening condition. A preoperative diagnosis is difficult to make. Majority of the cases are diagnosed intraoperatively followed by confirmation on histopathology. We presented a case of 32-year-old woman with previous two normal deliveries at 7 weeks gestation who presented with abdominal pain and spotting. She was diagnosed with ruptured ovarian ectopic pregnancy on laparotomy and salpingo-oophorectomy was done. Later, ovarian pregnancy was confirmed on histopathology. The incidence of ovarian ectopic pregnancy is increasing and it should be considered as a differential diagnosis in women of childbearing age coming to emergency department with abdominal pain. It is important to keep a high index of suspicion for its diagnosis. High resolution transvaginal ultrasonography can help in earlier detection and preventing some of its complications like rupture, shock and maternal mortality

Are synthesis and folding of proteins overlapping functions of the ribosomal RNA?

A general protein folding activity has been detected in the large subunit of the ribosome. This activity seems to be located in the peptidyl transferase domain of the large RNA of this subunit. In contrast to the protein folding activity of the molecular chaperones, this activity is (a) present in the RNA and is (b) universal, not selective for any protein. The overlap of this active site with the peptidyl transferase centre on the ribosomal RNA suggests a functional overlap between protein synthesis and folding by ribosome in the cell

Survey of Vertical Handoff Decision Criteria in LTE Cellular Networks

Vertical handover advantage brilliant importance because of the upgrades in mobility fashions by way of the Fourth era (4G) technology. A handover desire scheme in LTE networks both based totally on unmarried or multiple criteria. The wide variety of standards is right away depending on the overall handover time. In addition, the time required for deciding on a target network at some point of handover is also extended with the growth in a number of parameters. Conventional handover choice Strategies are specifically based at the unmarried parameter. But, with the advent of heterogeneous Wi-Fi networks, the overall performance of those unmarried parameter choice schemes is highly decreased. Consequently, researchers introduce multirequirements handover selection schemes. those enhancements are restricted to specific situations and for this reason do now not offer help for mounted mobility. Further, numerous schemes are proposed

Vertical Handoff Decision Criteria with LTE Network

A handover decision scheme in LTE networks either based on single or multiple criteria. The number of criteria is directly depending on the totalhandovertime.A vertical handover decision algorithm based on the fuzzy control theory. The algorithm takes into consider the factors of Power Level, Cost and Bandwidth. After establishing the membership functions, membership degrees of corresponding factors can be determined, which are processed by the Weight Vector. Finally, the Fuzzy Vertical Handoff Decision Vector is derived and vertical handover decision can be made. It is shown through simulation that the algorithm realizes the optimized vertical handover by evaluating and analyzing various input parameters

Online meeting assistance

Online meetings sometimes offer a poor user experience to participants. Participants benefit from being able to access prior portions of an ongoing meeting, e.g., that they missed due to connectivity problems or because of interruptions. This disclosure describes a meeting helper that, with user permission, records and transcribes meeting content. The content is made available during and after the meeting. The meeting helper eliminates the need for participants to take notes during a meeting and offers improved user experience

Role of cytokine in malignant T-cell metabolism and subsequent alternation in T-cell tumor microenvironment

T cells are an important component of adaptive immunity and T-cell-derived lymphomas are very complex due to many functional sub-types and functional elasticity of T-cells. As with other tumors, tissues specific factors are crucial in the development of T-cell lymphomas. In addition to neoplastic cells, T- cell lymphomas consist of a tumor micro-environment composed of normal cells and stroma. Numerous studies established the qualitative and quantitative differences between the tumor microenvironment and normal cell surroundings. Interaction between the various component of the tumor microenvironment is crucial since tumor cells can change the microenvironment and vice versa. In normal T-cell development, T-cells must respond to various stimulants deferentially and during these courses of adaptation. T-cells undergo various metabolic alterations. From the stage of quiescence to attention of fully active form T-cells undergoes various stage in terms of metabolic activity. Predominantly quiescent T-cells have ATP-generating metabolism while during the proliferative stage, their metabolism tilted towards the growth-promoting pathways. In addition to this, a functionally different subset of T-cells requires to activate the different metabolic pathways, and consequently, this regulation of the metabolic pathway control activation and function of T-cells. So, it is obvious that dynamic, and well-regulated metabolic pathways are important for the normal functioning of T-cells and their interaction with the microenvironment. There are various cell signaling mechanisms of metabolism are involved in this regulation and more and more studies have suggested the involvement of additional signaling in the development of the overall metabolic phenotype of T cells. These important signaling mediators include cytokines and hormones. The impact and role of these mediators especially the cytokines on the interplay between T-cell metabolism and the interaction of T-cells with their micro-environments in the context of T-cells lymphomas are discussed in this review article

The use of Brazilian vegetable oils in nanoemulsions: an update on preparation and biological applications

ABSTRACT Vegetable oils present important pharmacological properties, which gained ground in the pharmaceutical field. Its encapsulation in nanoemulsions is considered a promising strategy to facilitate the applicability of these natural compounds and to potentiate the actions. These formulations offer several advantages for topical and systemic delivery of cosmetic and pharmaceutical agents including controlled droplet size, protection of the vegetable oil to photo, thermal and volatilization instability and ability to dissolve and stabilize lipophilic drugs. For these reasons, the aim of this review is to report on some characteristics, preparation methods, applications and especially analyze recent research available in the literature concerning the use of vegetable oils with therapeutic characteristics as lipid core in nanoemulsions, specially from Brazilian flora, such as babassu (Orbignya oleifera), aroeira (Schinus molle L.), andiroba (Carapa guaianiensis), casca-de-anta (Drimys brasiliensis Miers), sucupira (Pterodon emarginatus Vogel) and carqueja doce (Stenachaenium megapotamicum) oils

Microbial pollution in water and its effect on fish

A systematic study of microbial contamination of fish grown in ponds in and around Calcutta was initiated as part of the wetland management project in the city. Ponds were either sewage-fed or conventional (i.e., fed by rain and groundwater). Fish from these ponds are used for human consumption, and therefore a quantitative analysis of their microbial content is necessary. When concentrations of Escherichia coli, Salmonelleae (unidentified species), and Staphylococcus aureus in water and different organs of fish from sewage-fed and conventional ponds were compared, water and fish organs from conventional ponds contained about two orders of magnitude more bacterial cells. We tested for Salmonelleae and S. aureus, in addition to E. coli, because of persistent reports from Calcutta hospitals that most enteric and other infectious diseases in this region are caused by these bacteria. Significant linear correlations were found between concentrations of these bacteria in pond water and their recovery from several tissues of the fish

Variation and storage stability of juices extracted from potatoes and their influence on in-situ coloration of wool

In this study, juices from four different varieties of potatoes are extracted and then stored at 4˚C. Thereafter enzymes have been assayed at different periods and the juices are applied for the coloration of wool. Results reveal that potato juices demonstrate good storage stability. Though there are variations in the quantity of enzymes present in potatoes, the same is not reflected in the K/S values of the wool. The polymerization of catechol with potato juice results in coloured quinone derivatives which further react to form dimers, oligomers and polymers as confirmed by UV-Vis spectroscopy studies.