Biological Properties and the Role of IL-25 in Disease Pathogenesis

The interleukin- (IL-) 17 superfamily, a T cell-derived cytokine, consists of 6 ligands (IL-17A–IL-17F) and 5 receptors (IL-17RA–IL-17RE). IL-17A, a prototype member of this family, is involved in the pathogenesis of allergies, autoimmune diseases, allograft transplantations, and malignancies. By contrast, IL-17B is reported to be closely related to certain diseases, particularly tumors such as breast cancer, gastric cancer, and pancreatic cancer. Recently, the biological function of IL-17E (also called IL-25) in disease, particularly airway diseases, has attracted the attention of researchers. However, studies on IL-25 are scant. In this review, we detail the structural characteristics, expression patterns, responder cells, biological properties, and role of IL-25 in disease pathogenesis

Data from: Heterogeneous and efficient transesterification of Jatropha curcas L. seed oil to produce biodiesel catalyzed by nano-sized SO42-/TiO2

Developing high-efficiency hetero-catalysts for transesterification reaction is of great importance in the production of biodiesel from Jatropha curcas L. seed oil (JO). Here, we synthesized a series of sulfated TiO2 by treating with varying H2SO4 concentration (xSO42-/TiO2) and TiO2 catalysts and applied to the transesterification of JO. Furthermore, these heterostructures were characterized by many characterization methods including XRD, FT–IR, N2–adsorption, SEM, TEM, TG, py-IR and NH3-TPD, and their catalytic performance were investigated under various operating conditions. The results reveal that both the Brønsted and Lewis acid sites are presented in the xSO42-/TiO2 catalysts, while only Lewis-type sites are observed in the TiO2 catalyst. And the acid intensity, surface area and mesoporous volume of catalysts are improved obviously after treating with sulfuric acid of TiO2. Then the xSO42-/TiO2 catalysts exhibit much higher catalytic activity than TiO2 catalyst, which is attributed to the larger surface area and mesoporous volume and stronger acidity. Furthermore, the reusability behavior of 1.5SO42-/TiO2 catalyst in transesterification of JO was also studied

Date-Heterogeneous and efficient transesterification of Jatropha curcas L. seed oil

Date-Heterogeneous and efficient transesterification of Jatropha curcas L. seed oi

Axially bound magnetic skyrmions: glueing topological strings across an interface

A major challenge in topological magnetism lies in the three-dimensional (3D) exploration of their magnetic textures. A recent focus has been the question of how 2D skyrmion sheets vertically stack to form distinct types of 3D topological strings. Being able to manipulate the vertical coupling should therefore provide a route to the engineering of topological states. Here, we present a new type of axially bound magnetic skyrmion string state in which the strings in two distinct materials are glued together across their interface. Using quasi-tomographic resonant elastic x-ray scattering, the 3D skyrmion profiles before and after their binding across the interface were unambiguously determined and compared. Their attractive binding is accompanied by repulsive twisting, i.e., the coupled skyrmions mutually affect each other via a compensating twisting. This state exists in chiral magnet-magnetic thin film heterostructures, providing a new arena for the engineering of 3D topological phases