QTL Mapping of Seed Vigor of Backcross Inbred Lines Derived From Oryza longistaminata Under Artificial Aging

Seed vigor is an important character of seed quality that promotes rice to germinate rapidly from soil and developing to a strong seedling, especially in the current rice direct-sowing production system. However, previous studies for seed vigor mainly concentrate in cultivars, and less reports involving in wild rice. In this study, 152 backcross inbred lines (BILs) derived from wild rice Oryza longistaminata were genotyped with re-sequencing technology, and QTLs for seed vigor related traits under normal and artificial aging treatment were analyzed. Totally, 36 QTLs were detected, of which, eight for germination potential (GP), 10 for germination rate (GR), 9 for seedling length (SL), and 9 for root length (RL). Among these, 14 novel QTLs were identified from O. longistaminata. Of which, six QTLs were related to germination, and eight related to seedling growth under aging stress. What’s more, the major QTLs q9SL1.1, q6SL1.1, and q3SL1.1 for seedling length were fallen in the same locus and fine-mapped an interval about 90 Kb. The major QTLs q9GR8.1 and q9GP8.1 related with germination were fine-mapped to an interval about 90 Kb. This work will provide us basis for breeding of high seed vigor rice in rice breeding programs and further cloning of these genes

Testing the Symmetric Assumption of Complementary Relationship: A Comparison between the Linear and Nonlinear Advection-Aridity Models in a Large Ephemeral Lake

The accuracy of a complementary relationship (CR) evapotranspiration (ET) model depends on how to parameterize the relationship between apparent potential ET and actual ET as the land surface changes from wet to dry. Yet, the validity of its inherent symmetric assumption of the original CR framework, i.e., the B value equal to one, is controversial. In this study, we conduct a comparative study between a linear, symmetric version (B = 1) and a nonlinear, asymmetric version (B is not necessarily equal to 1) of the advection-aridity (AA) CR model in a large ephemeral lake, which experiences dramatic changes in surface/atmosphere humidity. The results show that B was typically 1.1 ± 1.4 when ET ≤ ETPT ≤ ETPM, where ETPM and ETPT are estimated using the Penman (PM) and Priestley–Taylor (PT) equations, respectively; the AA model performed reasonably well in this case. However, the value of B can be negative and deviate from 1 significantly if the inequality ET ≤ ETPT ≤ ETPM is violated, which is quite common in humid environments. Because the actual ET can be negatively (B > 0) or positively (B < 0) related to the evaporative demand of the air, the nonlinear AA model generally performs better than the AA model if ET ≤ ETPM is satisfied. Although B is not significantly correlated with the atmospheric relative humidity (RH), both models, especially the nonlinear AA model, resulted in negative biases when ET > ETPM, which generally occur at high RH conditions. Both the linear and the nonlinear AA models performed better under higher water level conditions, however, our study highlights the need for higher-order (≥3) polynomial functions when CR models are applied in humid environments

Synthesis and Antifungal Activity of Novel Triazole Compounds Containing Piperazine Moiety

Design and synthesis of triazole library antifungal agents having piperazine side chains, analogues to fluconazole were documented. The synthesis highlighted utilization of the click chemistry on the basis of the active site of the cytochrome P450 14α-demethylase (CYP51). Their structures were characterized by 1H-NMR, 13C-NMR, MS and IR. The influences of piperazine moiety on in vitro antifungal activities of all the target compounds were evaluated against eight human pathogenic fungi

Synthesis and Antifungal Activity of Novel Triazole Compounds Containing Piperazine Moiety

Design and synthesis of triazole library antifungal agents having piperazine side chains, analogues to fluconazole were documented. The synthesis highlighted utilization of the click chemistry on the basis of the active site of the cytochrome P450 14α-demethylase (CYP51). Their structures were characterized by 1H-NMR, 13C-NMR, MS and IR. The influences of piperazine moiety on in vitro antifungal activities of all the target compounds were evaluated against eight human pathogenic fungi

Skin erosion following deep brain stimulator implantation: A case report

Deep brain stimulation (DBS) is an established safe neurosurgical symptomatic therapy for Parkinson's disease (PD) in whom medical treatment fails to provide adequate symptom control. Skin-related complications, particularly skin erosion, may lead to exposure of the DBS device, compromising the effectiveness of the DBS device. We presented a patient who suffered from skin erosion over bilateral burr hole site. A Multidisciplinary Team (MDT) approach was used to provide staged surgical treatment for scalp reconstruction. Without the removal of the DBS system. No alteration of DBS system efficacy was observed and the bilateral wounds healed well during the follow-up period